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MAP1S Gene

protein-coding   GIFtS: 51
GCID: GC19P017932

Microtubule-Associated Protein 1S

(Previous names: chromosome 19 open reading frame 5, VCY2 interacting protein...)
(Previous symbols: C19orf5, VCY2IP1, BPY2IP1)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Microtubule-Associated Protein 1S1 2     MAP-1S2 3
BPY2IP11 2 3 5     MAP82 3
VCY2IP11 2 3 5     VCY2IP-12 3
C19orf51 2 3     BPY2-Interacting Protein 12 3
BPY2 Interacting Protein 11 2     VCY2-Interacting Protein 12 3
VCY2 Interacting Protein 11 2     Chromosome 19 Open Reading Frame 51
Microtubule-Associated Protein 82 3     C19ORF55
Variable Charge Y Chromosome 2-Interacting Protein 12 3     

External Ids:    HGNC: 157151   Entrez Gene: 552012   Ensembl: ENSG000001304797   OMIM: 6075735   UniProtKB: Q66K743   

Export aliases for MAP1S gene to outside databases

Previous GC identifers: GC19P017694 GC19P017832 GC19P017396


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MAP1S Gene:
MAP1S (microtubule-associated protein 1S) is a protein-coding gene. GO annotations related to this gene include actin filament binding and identical protein binding. An important paralog of this gene is MAP1B.

UniProtKB/Swiss-Prot: MAP1S_HUMAN, Q66K74
Function: Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and
genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds
to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity)

Gene Wiki entry for MAP1S Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000019.9  NC_018930.2  NT_011295.12  
Regulatory elements:
   Regulatory transcription factor binding sites in the MAP1S gene promoter:
         ER-alpha   NRSF form 1   AP-2alpha isoform 2   NRSF form 2   Arnt   YY1   Max   ZIC2/Zic2   AP-2alpha   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMAP1S promoter sequence
   Search Chromatin IP Primers for MAP1S

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MAP1S


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.11   Ensembl cytogenetic band:  19p13.11   HGNC cytogenetic band: 19p13.12

MAP1S Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MAP1S gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P017932:  view genomic region     (about GC identifiers)

Start:
17,830,051 bp from pter      End:
17,845,325 bp from pter
Size:
15,275 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: MAP1S_HUMAN, Q66K74 (See protein sequence)
Recommended Name: Microtubule-associated protein 1S  
Size: 1059 amino acids; 112211 Da
Subunit: Heterodimer of a heavy and a light chain. Interacts with microtubules and actin. Both MAP1S heavy and
light chains interact with microtubules. MAP1S light chain interacts with actin. Interacts (via C-terminus) with
GAN (via Kelch domains) (By similarity). Interacts with ESR1, LRPPRC, RASSF1 isoform A and isoform C,
microtubules and VCY2. Interacts with WDR47 (via N-terminus of light chain)
Miscellaneous: Depletion of MAP1S by RNAi causes mitotic abnormalities that consist of failure to form a stable
metaphase plate, premature sister chromatid separation, lagging chromosomes, and multipolar spindles
Sequence caution: Sequence=AAH07253.1; Type=Erroneous initiation; Sequence=AAH07253.1; Type=Miscellaneous
discrepancy; Note=Contaminating sequence. At the N-terminus; Sequence=AAH67115.1; Type=Erroneous initiation;
Sequence=BAA91743.1; Type=Erroneous initiation; Sequence=BAB14415.1; Type=Erroneous initiation;
Sequence=BAB55242.1; Type=Frameshift; Positions=851; Sequence=BAB93493.1; Type=Erroneous initiation;
Sequence=CAD38911.1; Type=Erroneous initiation;
Secondary accessions: Q27QB1 Q6NXF1 Q8N3L8 Q8N3W5 Q8NI88 Q96H94 Q96IT4 Q96SP8 Q9BRC6 Q9H928
Q9NVK7

Explore the universe of human proteins at neXtProt for MAP1S: NX_Q66K74

Explore proteomics data for MAP1S at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys73, Lys380, Lys1000
  • Modification sites at PhosphoSitePlus

  • See MAP1S Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_060644.4  
    ENSEMBL proteins: 
     ENSP00000469571   ENSP00000325313   ENSP00000470306   ENSP00000471903   ENSP00000469123  
     ENSP00000469321   ENSP00000439243   ENSP00000469232   ENSP00000468878   ENSP00000469854  
     ENSP00000471994  

    MAP1S Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for MAP1S

     
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    antibodies-online proteins for MAP1S (6 products) 

     
    antibodies-online peptides for MAP1S

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    antibodies-online antibodies for MAP1S (27 products) 

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR026074 MAP1
     IPR001279 Beta-lactamas-like
     IPR027322 MAP1S

    Graphical View of Domain Structure for InterPro Entry Q66K74

    ProtoNet protein and cluster: Q66K74

    UniProtKB/Swiss-Prot: MAP1S_HUMAN, Q66K74
    Domain: The N-terminus of the heavy chain associates with the C-terminus of the light chain to form the
    heterodimer complex (By similarity). Its C-terminal part of the heavy chain interacts with ESR1
    Similarity: Belongs to the MAP1 family


    Find genes that share domains with MAP1S           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MAP1S_HUMAN, Q66K74
    Function: Microtubule-associated protein that mediates aggregation of mitochondria resulting in cell death and
    genomic destruction (MAGD). Plays a role in anchoring the microtubule organizing center to the centrosomes. Binds
    to DNA. Plays a role in apoptosis. Involved in the formation of microtubule bundles (By similarity)

         Gene Ontology (GO): Selected molecular function terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding IDA15907802
    GO:0004536NOT deoxyribonuclease activity IDA15907802
    GO:0005515protein binding IPI12762840
    GO:0008017microtubule binding TAS12762840
    GO:0015631tubulin binding IDA15528209
         
    Find genes that share ontologies with MAP1S           About GenesLikeMe


    Phenotypes:
         7 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Map1s):
     behavior/neurological  cardiovascular system  cellular  mortality/aging  muscle 
     no phenotypic analysis  reproductive system 

    Find genes that share phenotypes with MAP1S           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Map1stm1.1Lliu for MAP1S

       genOway: Develop your customized and physiologically relevant rodent model for MAP1S

    miRNA
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    miRTarBase miRNAs that target MAP1S:
    hsa-mir-296-3p (MIRT038459), hsa-mir-505-3p (MIRT041005), hsa-mir-339-5p (MIRT042810)

    Block miRNA regulation of human, mouse, rat MAP1S using miScript Target Protectors
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    Predesigned siRNA for gene silencing in human, mouse, rat MAP1S

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MAP1S_HUMAN, Q66K74: Nucleus. Cytoplasm, cytosol. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, spindle.
    Note=Detected in filopodia-like protrusions and synapses (By similarity). Detected in perinuclear punctate
    network corresponding to mitochondrial aggregates and in the nucleus in cells exhibiting apoptosis. Associated
    specifically with microtubules stabilized by paclitaxel and colocalizes with RASSF1 isoform A. In interphase
    cells, shows a diffuse cytoplasmic staining with partial localization to the microtubules. During the different
    stages of mitosis detected at the spindle microtubules
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytoskeleton5
    cytosol5
    nucleus5
    endoplasmic reticulum1
    mitochondrion1
    plasma membrane1
    vacuole1

    Gene Ontology (GO): Selected cellular component terms (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730nucleolus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005819spindle IEA--
    GO:0005829cytosol IDA12762840

    Find genes that share ontologies with MAP1S           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MAP1S
    Interactions:

        GeneGlobe Interaction Network for MAP1S

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for MAP1S (Q66K741, 2, 3 ENSP000003253134) via UniProtKB, MINT, STRING, and/or I2D (see all 118)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    BPY2O145991, 3, ENSP000003291064EBI-2133734,EBI-2133713 I2D: score=4 STRING: ENSP00000329106
    BPY2CO145991, 3, ENSP000003717244EBI-2133734,EBI-2133713 I2D: score=4 STRING: ENSP00000371724
    BPY2BO145991, 3EBI-2133734,EBI-2133713 I2D: score=4 
    SOCS3O145431, 2, 3, ENSP000003303414EBI-2133734,EBI-714146 MINT-6796936 MINT-6796894 MINT-6796909 MINT-6796957 MINT-6796979 MINT-6796875 I2D: score=2 STRING: ENSP00000330341
    RASSF5Q8WWW03, ENSP000003474434I2D: score=3 STRING: ENSP00000347443
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000226microtubule cytoskeleton organization ----
    GO:0001578microtubule bundle formation IMP15528209
    GO:0006309apoptotic DNA fragmentation TAS12762840
    GO:0006915apoptotic process ----
    GO:0007399nervous system development ISS16297881

    Find genes that share ontologies with MAP1S           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MAP1S



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for MAP1S gene: 
    NM_018174.4  

    Unigene Cluster for MAP1S:

    Microtubule-associated protein 1S
    Hs.66048  [show with all ESTs]
    Unigene Representative Sequence: BC067115
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 21):
    ENST00000594625 ENST00000324096(uc010eaz.2 uc002nhe.1) ENST00000600608
    ENST00000600186 ENST00000594212 ENST00000597735 ENST00000601544 ENST00000597681
    ENST00000594340 ENST00000597067 ENST00000599494 ENST00000544059(uc010xpv.1)
    ENST00000594365 ENST00000593593 ENST00000596637 ENST00000595338 ENST00000598769
    ENST00000598916
    miRNA
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      QuantiFast Probe-based Assays in human, mouse, rat MAP1S

    Additional mRNA sequence: 

    AB062430.1 AJ440784.1 AK001531.1 AK023118.1 AK027623.1 AK292555.1 AK294936.1 AK308975.1 
    AL834233.1 BC006358.2 BC007253.1 BC008806.2 BC067115.1 BC080547.1 BC113952.1 DQ387861.1 

    20 DOTS entries:

    DT.451566  DT.92431725  DT.100712123  DT.100697759  DT.92431727  DT.95081136  DT.97805423  DT.92431723 
    DT.95081148  DT.121431836  DT.91873454  DT.100734938  DT.100840448  DT.121431759  DT.121431824  DT.121431976 
    DT.121432215  DT.92431726  DT.99980073  DT.95081151 

    Selected AceView cDNA sequences (see all 214):

    F13449 BF812713 AL537972 CR593726 BC006358 AL834233 BC080547 AK001531 
    BX433575 CR610661 BM671685 BE893719 BC067115 CF132175 BC008806 BG111266 
    BM708467 BQ435181 CR620607 BQ431950 CO402032 CO246799 BG024834 BM689329 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for MAP1S    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c · 6d ^ 7 ^ 8
    SP1:              -                       -                                             
    SP2:              -     -                 -                                             
    SP3:              -                                                                     
    SP4:                                      -                                             
    SP5:                                                                                    


    ECgene alternative splicing isoforms for MAP1S

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MAP1S expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGGATGACG
    MAP1S Expression
    About this image

    MAP1S Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MAP1S Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.66048

    UniProtKB/Swiss-Prot: MAP1S_HUMAN, Q66K74
    Tissue specificity: Expressed in neurons (at protein level). Expressed in spermatocytes, spermatids and
    spermatozoa. Expressed in the cerebral cortex. Highly expressed in testis. Moderately expressed in the brain,
    colon, heart, kidney, liver, lung, placenta, small intestine, spleen and stomach. Weakly expressed in muscle

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAP1S

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for MAP1S gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Map1s1 , 5 microtubule-associated protein 1S1, 5 70.82(n)1
    72.3(a)1
      8 (34.41 cM)5
    2700581  NM_173013.31  NP_766601.21 
     709059745 
    chicken
    (Gallus gallus)
    Aves MAP1S6
    microtubule-associated protein 1S
    47(a)
    1 ↔ 1
    28(3199763-3203679)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia BX706226.12   -- 73.58(n)    BX706226.1 
    zebrafish
    (Danio rerio)
    Actinopterygii MAP1S (2 of 2)6
    MAP1S (1 of 2)6
    microtubule-associated protein 1S
    35(a)
    32(a)
    1 ↔ many
    1 ↔ many
    22(39677218-39711647) ENSDARG00000060805
    2(36641517-36653086) ENSDARG00000060326
    fruit fly
    (Drosophila melanogaster)
    Insecta futsch6
    dp6
    dumpy
    5(a)
    1(a)
    many ↔ many
    many ↔ many
    X(1303102-1345400)
    2L(4477462-4595054)


    ENSEMBL Gene Tree for MAP1S (if available)
    TreeFam Gene Tree for MAP1S (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MAP1S gene
    MAP1B2  MAP1A2  
    2 SIMAP similar genes for MAP1S using alignment to 11 protein entries:     MAP1S_HUMAN (see all proteins):
    MAP1B    MAP1A

    Find genes that share paralogs with MAP1S           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MAP1S (see all 489)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1503127341,2
    --17759597(+) AATAAA/CAGAAG 1 -- us2k10--------
    rs1858235911,2
    --17828346(+) GGAAGA/GATGCC 1 -- us2k10--------
    rs1386335571,2
    C--17828416(+) GGCTG-/TTACAC
    ACTGGCCA
    GGGAG
    1 -- us2k10--------
    rs1129480521,2
    C--17828474(+) AGCGGA/GAGGCT 1 -- us2k11Minor allele frequency- G:0.00CSA 1
    rs1160931991,2
    F--17828534(+) ACTCCC/TGGAGA 1 -- us2k11Minor allele frequency- T:0.05WA 118
    rs1162717771,2
    C,F--17828535(+) CTCCCG/AGAGAC 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs353966521,2
    C,F--17828600(+) TCCAGA/CAGTTC 1 -- us2k15Minor allele frequency- C:0.18NA EA 246
    rs1382803601,2
    --17828668(+) AGGCGC/TGGCGG 1 -- us2k10--------
    rs1496071201,2
    --17828671(+) CGCGGC/TGGCTC 1 -- us2k10--------
    rs1467182501,2
    C--17828683(+) CGCCTA/GTAATC 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for MAP1S (17830051 - 17845325 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 8 variations for MAP1S:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1349147CNV Insertion17803354
    dgv3764n71CNV Loss21882294
    dgv50n68CNV Loss17160897
    dgv3763n71CNV Loss21882294
    nsv911208CNV Loss21882294
    nsv911214CNV Loss21882294
    nsv911209CNV Loss21882294
    dgv3765n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MAP1S
    DNA2.0 Custom Variant and Variant Library Synthesis for MAP1S

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 607573    OMIM disorders: --


    Find genes that share disorders with MAP1S           About GenesLikeMe


    Export disorders for MAP1S gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MAP1S gene, integrated from 10 sources (see all 46):
    (articles sorted by number of sources associating them with MAP1S)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of a VCY2 interacting protein-1; VCY2IP-1, a MAP-like protein. (PubMed id 14627543)1, 2, 3, 9 Wong E.Y.... Yeung W.S. (Biol. Reprod. 2004)
    2. Microtubule-associated protein 8 contains two microtubule binding sites. (PubMed id 16297881)1, 2, 3 Ding J....Yang Y. (Biochem. Biophys. Res. Commun. 2006)
    3. Sequence analysis of LRPPRC and its SEC1 domain interaction partners suggests roles in cytoskeletal organization, vesicular trafficking, nucleocytosolic shuttling, and chromosome activity. (PubMed id 11827465)1, 2, 3 Liu L. and McKeehan W.L. (Genomics 2002)
    4. Putative tumor suppressor RASSF1 interactive protein and cell death inducer C19ORF5 is a DNA binding protein. (PubMed id 15907802)1, 2, 9 Liu L.... McKeehan W.L. (Biochem. Biophys. Res. Commun. 2005)
    5. Microtubule-associated protein 1S, a short and ubiquitously expressed member of the microtubule-associated protein 1 family. (PubMed id 15528209)1, 3, 9 OrbA!n-NAcmeth Z....Propst F. (J. Biol. Chem. 2005)
    6. The NMDAR subunit NR3A interacts with microtubule-associated protein 1S in the brain. (PubMed id 17658481)1, 2 Eriksson M.... Sundstroem E. (Biochem. Biophys. Res. Commun. 2007)
    7. Specificity of the methylation-suppressed A isoform of candidate tumor suppressor RASSF1 for microtubule hyperstabilization is determined by cell death inducer C19ORF5. (PubMed id 15753381)1, 2 Liu L.... McKeehan W.L. (Cancer Res. 2005)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    9. RASSF1A interacts with microtubule-associated proteins and modulates microtubule dynamics. (PubMed id 15205320)1, 2 Dallol A.... Latif F. (Cancer Res. 2004)
    10. Novel complex integrating mitochondria and the microtubular cytoskeleton with chromosome remodeling and tumor suppressor RASSF1 deduced by in silico homology analysis, interaction cloning in yeast, and colocalization in cultured cells. (PubMed id 12762840)1, 2 Liu L.... McKeehan W.L. (In Vitro Cell. Dev. Biol. Anim. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55201 HGNC: 15715 AceView: BPY2IP1 Ensembl:ENSG00000130479 euGenes: HUgn55201
    ECgene: MAP1S H-InvDB: MAP1S

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MAP1S Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for MAP1S gene:
    Search GeneIP for patents involving MAP1S

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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