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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MAP1LC3B Gene

protein-coding   GIFtS: 54
GCID: GC16P087425

microtubule-associated protein 1 light chain 3 beta

 Explore 11 diseases affiliated with
MAP1LC3B via our new
 Human Malady Compendium 
Biological research products
for MAP1LC3B
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Microtubule-Associated Protein 1 Light Chain 3 Beta1 2 3     LC3B2
ATG8F1 2     MAP1A/1BLC32
Autophagy-Related Ubiquitin-Like Modifier LC3 B2 3     MAP1LC3B-A1
MAP1 Light Chain 3-Like Protein 22 3     Microtubule-Associated Proteins 1A/1B Light Chain 3B2
MAP1A/MAP1B LC3 B2 3     MAP1ALC33
MAP1A/MAP1B Light Chain 3 B2 3     Autophagy-Related Protein LC3 B3

External Ids:    HGNC: 133521   Entrez Gene: 816312   Ensembl: ENSG000001409417   OMIM: 6096045   UniProtKB: Q9GZQ83   

Export aliases for MAP1LC3B gene to outside databases

Previous GC identifers: GC16P078763 GC16P088456 GC16P087166 GC16P087206 GC16P087207 GC16P085982 GC16P073168


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MAP1LC3B:
The product of this gene is a subunit of neuronal microtubule-associated MAP1A and MAP1B proteins, which are involved
in microtubule assembly and important for neurogenesis. Studies on the rat homolog implicate a role for this gene in
autophagy, a process that involves the bulk degradation of cytoplasmic component. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: MLP3B_HUMAN, Q9GZQ8
Function: Involved in formation of autophagosomal vacuoles (autophagosomes)

Gene Wiki entry for MAP1LC3B


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000016.9  NC_018927.1  NT_010498.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MAP1LC3B gene promoter:
         AhR   RP58   Pax-2   Pax-2a   Arnt   C/EBPalpha   AREB6   MEF-2A   aMEF-2   LyF-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMAP1LC3B promoter sequence
   Search SABiosciences Chromatin IP Primers for MAP1LC3B

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAP1LC3B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q24.2   Ensembl cytogenetic band:  16q24.2   HGNC cytogenetic band: 16q24.2

MAP1LC3B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MAP1LC3B gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16P087425:  view genomic region     (about GC identifiers)

Start:
87,417,601 bp from pter      End:
87,438,385 bp from pter
Size:
20,785 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MLP3B_HUMAN, Q9GZQ8 (See protein sequence)
Recommended Name: Microtubule-associated proteins 1A/1B light chain 3B precursor  
Size: 125 amino acids; 14688 Da
Subunit: 3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins (By similarity).
Interacts at microtubules with CABP1 (via EF-hands 1 and 2) but not with calmodulin. Interacts with FYCO1 (via
C-terminus). Interacts with TP53INP1 and TP53INP2. Interacts with TBC1D25. Directly interacts with SQSTM1; this
interaction leads to MAP1LC3B recruitment to inclusion bodies containing polyubiquitinated protein aggregates and to
inclusion body degradation by autophagy
Subcellular location: Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome
membrane; Lipid-anchor. Note=LC3-II binds to the autophagic membranes
Caution: PubMed:12740394 has shown that the protein is cleaved at Lys-122 but PubMed:15355958 has shown that the
cleavage site is at Gly-120 as in other mammalian orthologs
2 PDB 3D structures from and Proteopedia for MAP1LC3B:
1V49 (3D)        2ZJD (3D)    
Secondary accessions: Q6NW02

Explore the universe of human proteins at neXtProt for MAP1LC3B: NX_Q9GZQ8

Post-translational modifications:

  • The precursor molecule is cleaved by APG4B/ATG4B to form LC3-I. This is activated by APG7L/ATG7, transferred to ATG3
  • and conjugated to phospholipid to form LC3-II1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9GZQ8

  • MAP1LC3B Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_073729.1  
    ENSEMBL proteins: 
     ENSP00000268607   ENSP00000457141   ENSP00000457225   ENSP00000454293   ENSP00000441125  

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    Browse Proteins at Uscn

    Gene Ontology (GO): 5/14 cellular component terms (GO ID links to tree view) (see all 14):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000421autophagic vacuole membrane IEA--
    GO:0005622intracellular IDA--
    GO:0005625soluble fraction ----
    GO:0005626insoluble fraction ----
    GO:0005737cytoplasm ----


    MAP1LC3B for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    MAP1LC3B for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR004241 Atg8_ubiquitin-like

    Graphical View of Domain Structure for InterPro Entry Q9GZQ8

    ProtoNet protein and cluster: Q9GZQ8

    1 Blocks protein family: IPB004241 Light chain 3 (LC3)

    UniProtKB/Swiss-Prot: MLP3B_HUMAN, Q9GZQ8
    Similarity: Belongs to the MAP1 LC3 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: MLP3B_HUMAN, Q9GZQ8
    Function: Involved in formation of autophagosomal vacuoles (autophagosomes)

    miRNA
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    hsa-miR-320a hsa-miR-600 hsa-miR-4328 hsa-miR-188-5p hsa-miR-196a* hsa-miR-320d hsa-miR-3653 hsa-miR-548l
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    Inhib. RNA
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    Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0008017microtubule binding ----
    GO:0015631tubulin binding ----
    GO:0019904protein domain specific binding ----


    MAP1LC3B for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-out Map1lc3btm1Mrab for MAP1LC3B
         1 MGI mutant phenotype (inferred from 1 allele(MGI details for Map1lc3b):
     normal 

    MAP1LC3B for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Protein Stability
    Protein Stability1.00
    2Apoptosis and Autophagy
    Apoptosis and Autophagy1.00
    3Senescence and Autophagy
    Senescence and Autophagy1.00
    4Glucose / Energy Metabolism
    Glucose / Energy Metabolism1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    3 Cell Signaling Technology (CST) Pathways for MAP1LC3B
        Apoptosis and Autophagy
    Glucose / Energy Metabolism
    Protein Stability

    1 BioSystems Pathway for MAP1LC3B 
        Senescence and Autophagy



    MAP1LC3B for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MAP1LC3B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/475 Interacting proteins for MAP1LC3B (Q9GZQ81, 2, 3 ENSP000002686074) via UniProtKB, MINT, STRING, and/or I2D (see all 475)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HIST1H4AP628053I2D: score=1 
    HIST1H4BP628053I2D: score=1 
    HIST1H4CP628053I2D: score=1 
    HIST1H4DP628053I2D: score=1 
    HIST1H4EP628053I2D: score=1 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006914autophagy IEA--
    GO:0032092positive regulation of protein binding ----


    MAP1LC3B for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MAP1LC3B
    Search CenterWatch for drugs/clinical trials and news about MAP1LC3B / MLP3B 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MAP1LC3B gene: 
    NM_022818.4  

    Unigene Cluster for MAP1LC3B:

    Microtubule-associated protein 1 light chain 3 beta
    Hs.356061  [show with all ESTs]
    Unigene Representative Sequence: BC041874
    9 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000561823 ENST00000562778 ENST00000563720 ENST00000268607(uc002fjx.3 uc010chs.3)
    ENST00000570189 ENST00000565788 ENST00000564844 ENST00000564638 ENST00000534986


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    8/17 QIAGEN miScript miRNA Assays for microRNAs that regulate MAP1LC3B (see all 17):
    hsa-miR-320a hsa-miR-600 hsa-miR-4328 hsa-miR-188-5p hsa-miR-196a* hsa-miR-320d hsa-miR-3653 hsa-miR-548l
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    Additional cDNA sequence: 

    AF087871.1 AF183417.1 AF303888.1 AK024571.1 AK025556.1 AK290956.1 AK310224.1 AK310335.1 
    AL834298.1 BC018634.2 BC041874.1 BC045759.1 BC048009.1 BC067797.1 JN663879.1 

    21 DOTS entries:

    DT.95221181  DT.100704332  DT.449196  DT.100726656  DT.120672878  DT.91993419  DT.91771666  DT.120672783 
    DT.120672855  DT.120672788  DT.100828078  DT.120371  DT.100828076  DT.120672874  DT.99952187  DT.120672807 
    DT.120672842  DT.120672896  DT.95154591  DT.99971773  DT.95107000 

    24/601 AceView cDNA sequences (see all 601):

    BQ614147 AI201397 AI222181 BX397339 BU631087 AI066413 BQ576020 CA443956 
    BM875333 CA306495 CR611354 AW005744 BU675477 AI754734 AA808234 W31938 
    AI937122 BU620381 N59726 CR614938 CA309688 W25645 BU675430 BU783930 

    GeneLoc Exon Structure

    2 Alternative Splicing Database (ASD) splice patterns (SP) for MAP1LC3B    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b
    SP1:                                    
    SP2:                                    


    ECgene alternative splicing isoforms for MAP1LC3B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MAP1LC3B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TGAGTGGTCA

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See MAP1LC3B Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MAP1LC3B

    SOURCE GeneReport for Unigene cluster: Hs.356061

    UniProtKB/Swiss-Prot: MLP3B_HUMAN, Q9GZQ8
    Tissue specificity: Most abundant in heart, brain, skeletal muscle and testis. Little expression observed in liver

        SABiosciences Expression via Pathway-Focused PCR Array including MAP1LC3B: 
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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for MAP1LC3B gene from 8/24 species (see all 24)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves MAP1LC3B1 microtubule-associated protein 1 light chain 3 beta 83.47(n)
    95.2(a)
      427559  NM_001031461.1  NP_001026632.1 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    74(a)
    1 → many
    GL343957.1(75975-79008)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC687442 hypothetical protein MGC68744 79.78(n)    BC060359.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufb60g112 wufb60g11 76.22(n)   322425  BC049313.1 
    honey bee
    (Apis mellifera)
    Insecta --
    --
    62(a)
    1 → many
    Group2.12(671918-672669)
    worm
    (Caenorhabditis elegans)
    Secernentea lgg-26
    Protein lgg-2
    52(a)
    1 → many
    IV(10934170-10935884)
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons ATATG8E6
    ATG8F6
    (see all 7)
    autophagy-related protein 8f
    (see all 7)
    37(a)
    36(a)
    (see all 7)
    possible ortholog
    possible ortholog
    (see all 7)
    2(18624264-18625717)
    4(9306663-9308462)
    rice
    (Oryza sativa)
    Liliopsida --
    --
    (see all 3)
    autophagy-related protein, putative, expressed
    (see all 3)
    37(a)
    35(a)
    (see all 3)
    possible ortholog
    possible ortholog
    (see all 3)
    8(5363352-5365506)
    4(31531261-31534066)


    ENSEMBL Gene Tree for MAP1LC3B (if available)
    TreeFam Gene Tree for MAP1LC3B (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MAP1LC3B gene
    GABARAPL22  MAP1LC3C2  GABARAP2  MAP1LC3A2  GABARAPL32  MAP1LC3B22  GABARAPL12  
    8 SIMAP similar genes for MAP1LC3B using alignment to 6 protein entries:     MLP3B_HUMAN (see all proteins):
    DKFZp762B153    MAP1LC3B2    MAP1LC3A    MAP1LC3C    GABARAPL2    GABARAPL3
    GABARAP    GABARAPL1

    MAP1LC3B for paralogs           About GeneDecksing


    5/9 Pseudogenes.org Pseudogenes for MAP1LC3B (see all 9)
    PGOHUM00000239518 PGOHUM00000239883 PGOHUM00000239936 PGOHUM00000235068 PGOHUM00000244369


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/252 NCBI SNPs in MAP1LC3B are shown (see all 252    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1854840341,2
    --87427797(+) CTCCCA/CTTTAA 1 -- int10--------
    rs1470989921,2
    --87427831(+) TAGAAA/TTGTGT 1 -- int10--------
    rs1165803121,2
    F,--87427844(+) AATATC/GTTAAC 1 -- int11Minor allele frequency- G:0.02WA 118
    rs796421221,2
    --87427870(+) TTGCTC/TCTGAT 1 -- int10--------
    rs616780211,2
    C--87427886(+) AAAAAA/-TCTTT 1 -- int11Minor allele frequency- -:0.00NA 2
    rs1907882651,2
    --87427933(+) TGATCA/GTGAGT 1 -- int10--------
    rs1435601491,2
    --87427946(+) TGACAA/GTTTTC 1 -- int10--------
    rs1131379781,2
    C,F,--87428012(+) TGGAGC/TCTAAG 1 -- int11Minor allele frequency- T:0.03NA 120
    rs1817081831,2
    --87428066(+) AGTGAA/GTTTAA 1 -- int10--------
    rs1119644751,2
    --87428295(+) CATCAC/TTTCCA 1 -- int12Minor allele frequency- T:0.00CSA 2

    HapMap Linkage Disequilibrium report for MAP1LC3B (87417601 - 87438385 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 1 variation for MAP1LC3B
         1 CNV: 4970

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    MAP1LC3B for disorders           About GeneDecksing

    OMIM gene information: 609604    OMIM disorders: --

    11 diseases for MAP1LC3B:    About MalaCards
    renal tubular acidosis    nephrocalcinosis    neuronitis    pulmonary hypertension
    pheochromocytoma    hypertension    breast carcinoma    lung cancer
    hypoxia    carcinoma    malaria


    Export disorders for MAP1LC3B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MAP1LC3B gene, integrated from 9 sources (see all 52):
    (articles sorted by number of sources associating them with MAP1LC3B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Human light chain 3/MAP1LC3B is cleaved at its carboxyl-terminal Met121 to expose Gly120 for lipidation and targeting to autophagosomal membranes. (PubMed id 15355958)1, 2, 9 Tanida I.... Kominami E. (2004)
    2. OATL1, a novel autophagosome-resident Rab33B-GAP, reg ulates autophagosomal maturation. (PubMed id 21383079)1, 2 Itoh T....Fukuda M. (2011)
    3. LC3 conjugation system in mammalian autophagy. (PubMed id 15325588)1, 2 Tanida I.... Kominami E. (2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates. (PubMed id 15187094)1, 2 Tanida I....Kominami E. (2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Gene expression profiles in human non-small and small-cell lung cancers. (PubMed id 12932674)1, 2 Difilippantonio S....Petersen I. (2003)
    8. Post-translational modifications of three members of the human MAP1LC3 family and detection of a novel type of modification for MAP1LC3B. (PubMed id 12740394)1, 2 He H.... Yu L. (2003)
    9. The gene expression profiling of sporadic pheochromocytoma and novel full-length cDNAs cloning. (PubMed id 14713272)1, 2 Yang Y.-S.... Chen J.-L. (2003)
    10. The unfolded protein response protects human tumor ce lls during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5. (PubMed id 20038797)1, 9 Rouschop K.M....Wouters B.G. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 81631 HGNC: 13352 AceView: MAP1LC3B Ensembl:ENSG00000140941 euGenes: HUgn81631
    ECgene: MAP1LC3B H-InvDB: MAP1LC3B

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MAP1LC3B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MAP1LC3B gene:
    Search GeneIP for patents involving MAP1LC3B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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