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protein-coding   GIFtS: 72
GCID: GC0XP043515

Monoamine Oxidase A

  See MAOA-related diseases

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Monoamine Oxidase A1 2
Monoamine Oxidase Type A2 3
MAO-A2 3
EC 8
Amine Oxidase [Flavin-Containing] A2
EC 1.4.38

External Ids:    HGNC: 68331   Entrez Gene: 41282   Ensembl: ENSG000001892217   OMIM: 3098505   UniProtKB: P213973   

Export aliases for MAOA gene to outside databases

Previous GC identifiers: GC0XP041545 GC0XP041794 GC0XP042360 GC0XP042636 GC0XP043271 GC0XP043400 GC0XP041246

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MAOA Gene:
This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the
oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results
in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including
antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
(provided by RefSeq, Jul 2012)

GeneCards Summary for MAOA Gene:
MAOA (monoamine oxidase A) is a protein-coding gene. Diseases associated with MAOA include brunner syndrome, and avoidant personality disorder. GO annotations related to this gene include primary amine oxidase activity. An important paralog of this gene is MAOB.

UniProtKB/Swiss-Prot: AOFA_HUMAN, P21397
Function: Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the
metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA
preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine

summary for MAOA Gene:
Monoamine Oxidases (MAO) catalyze the oxidation of monoamines such as dopamine, serotonin and adrenalin.
They are found bound to the outer membrane of mitochondria in most cell types in the body. Two subtypes of
monoamine oxidase have been identified: MAO-A and MAO-B. Both are found in neurons and astroglia, with MAO-A
also found in the liver, gastrointestinal tract and placenta and MAO-B in blood platelets. Abnormal
regulation of MAOs in the body has been associated with depression, substance abuse, attention deficit
disorder, and irregular sexual maturation.

Gene Wiki entry for MAOA (Monoamine oxidase A) Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence at NCBI GenBank:
NC_000023.10  NC_018934.2  NT_079573.5  
Regulatory elements:
   Regulatory transcription factor binding sites in the MAOA gene promoter:
         MEF-2A   c-Fos   AP-1   ATF-2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMAOA promoter sequence
   Search Chromatin IP Primers for MAOA

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MAOA

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp11.3   Ensembl cytogenetic band:  Xp11.3   HGNC cytogenetic band: Xp11.4-p11.3

MAOA Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MAOA gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP043515:  view genomic region     (about GC identifiers)

43,515,409 bp from pter      End:
43,606,068 bp from pter
90,660 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, antibodies-online, and/or GeneTex,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or GeneTex.)
About This Section

UniProtKB/Swiss-Prot: AOFA_HUMAN, P21397 (See protein sequence)
Recommended Name: Amine oxidase [flavin-containing] A  
Size: 527 amino acids; 59682 Da
Cofactor: FAD
Subunit: Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a
covalently bound flavin. Enzymatically active as monomer
Mass spectrometry: Mass=60512; Mass_error=6; Method=Electrospray; Range=1-527; Source=PubMed:11812236;
5 PDB 3D structures from and Proteopedia for MAOA:
1H8Q (3D)        2BXR (3D)        2BXS (3D)        2Z5X (3D)        2Z5Y (3D)    
Secondary accessions: B4DF46 Q16426
Alternative splicing: 2 isoforms:  P21397-1   P21397-2   

Explore the universe of human proteins at neXtProt for MAOA: NX_P21397

Explore proteomics data for MAOA at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys469
  • Modification sites at PhosphoSitePlus
  • Selected DME Specific Peptides for MAOA (P21397) (see all 22)

    See MAOA Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_000231.1  NP_001257387.1  

    ENSEMBL proteins: 
     ENSP00000340684   ENSP00000440846  
    Reactome Protein details: P21397

    MAOA Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for MAOA
    OriGene Custom MassSpec
    OriGene Custom Protein Services for MAOA
    GenScript Custom Purified and Recombinant Proteins Services for MAOA
    Novus Biologicals MAOA Protein
    Novus Biologicals MAOA Lysates
    Sino Biological Recombinant Protein for MAOA
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MAOA

    Search eBioscience for Proteins for MAOA 

    antibodies-online proteins for MAOA (10 products) 

    antibodies-online peptides for MAOA

    Search GeneTex for Proteins for MAOA 

    MAOA Antibody Products:

    EMD Millipore Mono- and Polyclonal Antibodies for the study of MAOA
    Browse R&D Systems for Antibodies
    OriGene Antibodies for MAOA
    OriGene Custom Antibody Services for MAOA
    Novus Biologicals MAOA Antibodies
    Abcam antibodies for MAOA (P21397, P27338)
    Cloud-Clone Corp. Antibodies for MAOA
    ThermoFisher Antibodies for MAOA
    antibodies-online antibodies for MAOA (54 products) 

    GeneTex Antibodies for MAOA:  
                        MAOA Antibodies

    MAOA Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for MAOA
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for MAOA
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for MAOA
    Cloud-Clone Corp. CLIAs for MAOA
    Search eBioscience for ELISAs for MAOA 
    antibodies-online kits for MAOA (26 products) 

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GenesLikeMe)
    About This Section

    2 InterPro protein domains:
     IPR001613 Flavin_amine_oxidase
     IPR002937 Amino_oxidase

    Graphical View of Domain Structure for InterPro Entry P21397

    ProtoNet protein and cluster: P21397

    1 Blocks protein domain: IPB001613 Flavin-containing amine oxidase signature

    UniProtKB/Swiss-Prot: AOFA_HUMAN, P21397
    Similarity: Belongs to the flavin monoamine oxidase family

    Find genes that share domains with MAOA           About GenesLikeMe

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway, and/or Taconic Biosciences, CRISPR knockouts from OriGene, transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Clones from OriGene, GenScript, Sino Biological, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: AOFA_HUMAN, P21397
    Function: Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the
    metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA
    preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine
    Catalytic activity: RCH(2)NHR' + H(2)O + O(2) = RCHO + R'NH(2) + H(2)O(2)

         Genatlas biochemistry entry for MAOA:
    monoamine oxidase A,overexpressed in female panic disorders

         Enzyme Numbers (IUBMB): EC 2 EC 1.4.32

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008131primary amine oxidase activity TAS--
    GO:0016491oxidoreductase activity ----
    GO:0050660flavin adenine dinucleotide binding ----
    Find genes that share ontologies with MAOA           About GenesLikeMe

         1 GenomeRNAi human phenotype for MAOA:
     Decreased viability 

         4 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Maoa):
     behavior/neurological  cardiovascular system  homeostasis/metabolism  nervous system 

    Find genes that share phenotypes with MAOA           About GenesLikeMe

    Animal Models:
         MGI mouse knock-out Maoatm1Shih for MAOA

       genOway: Develop your customized and physiologically relevant rodent model for MAOA

        Taconic Biosicences: Generate A Custom CRISPR Mouse Model For Your Study 

    CRISPR Knockouts: 
       OriGene CRISPR knockouts for MAOA

    miRTarBase miRNAs that target MAOA:
    hsa-mir-22-3p (MIRT005902)

    Block miRNA regulation of human, mouse, rat MAOA using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MAOA (see all 13):
    hsa-miR-3163 hsa-miR-495 hsa-miR-767-3p hsa-miR-7-2* hsa-miR-1324 hsa-miR-3065-5p hsa-miR-624* hsa-miR-29b-1*
    SwitchGear 3'UTR luciferase reporter plasmidMAOA 3' UTR sequence
    Inhib. RNA
    OriGene RNAi products in human, mouse, rat for MAOA
    Predesigned siRNA for gene silencing in human, mouse, rat MAOA

    OriGene clones in human, mouse for MAOA (see all 7)
    OriGene ORF clones in mouse, rat for MAOA
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MAOA (NM_000240)
    Sino Biological Human cDNA Clone for MAOA
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAOA

    Cell Line
    GenScript Custom overexpressing Cell Line Services for MAOA
    Browse ESI BIO Cell Lines and PureStem Progenitors for MAOA 
    In Situ Assay

    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAOA

    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
    About This Section

    Subcellular locations from UniProtKB/Swiss-Prot
    AOFA_HUMAN, P21397: Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side
    Subcellular locations from COMPARTMENTS: 

    plasma membrane1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--
    GO:0005741mitochondrial outer membrane TAS--
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with MAOA           About GenesLikeMe

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GenesLikeMe, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
    About This Section

    SuperPaths for MAOA About   (see all 25)  
    See pathways by source

    SuperPathContained pathways About
    1Serotonin clearance from the synaptic cleft
    Serotonin clearance from the synaptic cleft0.33
    Metabolism of serotonin0.00
    Enzymatic degradation of dopamine by COMT0.33
    Enzymatic degradation of Dopamine by monoamine oxidase0.00
    melatonin degradation II0.00
    2Phenylalanine metabolism
    Phenylalanine metabolism0.36
    noradrenaline and adrenaline degradation0.31
    Tyrosine metabolism0.36
    phenylalanine degradation IV0.00
    phenylalanine utilization0.33
    Metabolic pathways0.38
    4Transmission across Chemical Synapses
    Transmission across Chemical Synapses0.72
    Dopamine clearance from the synaptic cleft0.00
    Neuronal System0.68
    Neurotransmitter Clearance In The Synaptic Cleft0.00
    5tryptophan utilization II
    tryptophan utilization II0.71
    superpathway of melatonin degradation0.00
    tryptophan utilization I0.71
    serotonin degradation0.00

    Find genes that share SuperPaths with MAOA           About GenesLikeMe

    Pathways by source                                   See SuperPaths
    Show all pathways

    1 GeneGo (Thomson Reuters) Pathway for MAOA
        Tyrosine metabolism p.1 (dopamine)

    Selected BioSystems Pathways for MAOA (see all 15)
        Biogenic Amine Synthesis
    SIDS Susceptibility Pathways
    Oxidative Stress
    dopamine degradation
    serotonin degradation

    5 Reactome Pathways for MAOA
        Enzymatic degradation of dopamine by COMT
    Metabolism of serotonin
    Enzymatic degradation of Dopamine by monoamine oxidase
    Norepinephrine Neurotransmitter Release Cycle
    Monoamines are oxidized to aldehydes by MAOA and MAOB, producing NH3 and H2O2

    1 PharmGKB Pathway for MAOA
        Selective Serotonin Reuptake Inhibitor Pathway, Pharmacodynamics

    Selected Kegg Pathways  (Kegg details for MAOA) (see all 13):
        Glycine, serine and threonine metabolism
    Arginine and proline metabolism
    Histidine metabolism
    Tyrosine metabolism
    Phenylalanine metabolism

        Pathway & Disease-focused RT2 Profiler PCR Arrays including MAOA: 
              Amino Acid Metabolism II in human mouse rat
              Drug Metabolism: Phase I Enzymes in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat


        GeneGlobe Interaction Network for MAOA

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for MAOA (P213972, 3 ENSP000003406844) via UniProtKB, MINT, STRING, and/or I2D (see all 94)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    NDRG1Q925973, ENSP000003199774I2D: score=3 STRING: ENSP00000319977
    ATP6V1B2P212812, ENSP000002763904MINT-4054731 STRING: ENSP00000276390
    YWHABP319463I2D: score=1 
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006576cellular biogenic amine metabolic process TAS8211186
    GO:0006805xenobiotic metabolic process TAS--
    GO:0007268synaptic transmission TAS--
    GO:0007269neurotransmitter secretion TAS--
    GO:0007610behavior ----

    Find genes that share ontologies with MAOA           About GenesLikeMe

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, Sets of similar genes according to GenesLikeMe)
    About This Section

    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Compounds for MAOA available from Tocris Bioscience    About this table
    CompoundAction CAS #
    Rasagiline mesylate Selective, irreversible MAO-B inhibitor [161735-79-1]
    (R)-(-)-Deprenyl hydrochlorideMAO-B inhibitor[14611-52-0]
    MoclobemideReversible MAO-A inhibitor[71320-77-9]
    Lazabemide hydrochlorideSelective MAO-B inhibitor[103878-83-7]
    Bifemelane hydrochlorideMAO-A and MAO-B inhibitor[90293-01-9]

    Selected HMDB Compounds for MAOA (see all 43)    About this table
    CompoundSynonyms CAS #PubMed Ids
    1-Methylhistamine1-Methyl-1H-imidazole-4-ethanamine (see all 21)501-75-7--
    1-Phenylethylaminea-phenylethylamine (see all 17)98-84-0--
    3,4-Dihydroxymandelaldehyde3,4-Dihydroxyphenylglycolaldehyde (see all 4)13023-73-9--
    3,4-DihydroxyphenylacetaldehydeProtocatechuatealdehyde (see all 2)5707-55-1--
    3-Methoxy-4-hydroxyphenylglycolaldehydea,4-dihydroxy-3-methoxy-Benzeneacetaldehyde (see all 4)17592-23-3--
    3-Methoxytyramine3-Methoxy-4-hydroxyphenylethyl amine (see all 7)554-52-9--
    4,6-Dihydroxyquinoline4,6-Quinolinediol (see all 2)3517-61-1--
    5-Hydroxyindoleacetaldehyde(5-hydroxy-1H-indol-3-yl)acetaldehyde (see all 6)1892-21-3--
    5-Hydroxykynurenamine5-Hydroxykynuramine (see all 3)708-23-6--
    5-Methoxytryptamine2-(5-Methoxy-1H-indol-3-yl)ethanamine (see all 10)608-07-1--

    Selected DrugBank Compounds for MAOA (see all 37)    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Tranylcypromine-- 155-09-9targetinhibitor12504917 8749840 15351283 15276688 10548268 14574774 11752352 20655983 16495723 10027835 15049511 10494892 9829163
    Phenelzine-- 51-71-8targetantagonist17768678 17912044 14574774 11752352 7092487 19201819 16370964 18700056 9829163
    enzymesubstrate17768678 17912044 14574774 11752352 7092487 19201819 16370964 18700056 9829163 17768678
    PargylineBenzyl-methyl-2-propinylamin (see all 12)555-57-7targetinhibitor19300583 17823646 9564606 477738 16641841 17715422
    Phentermine-- 122-09-8targetantagonist11911838 11673765 10799660 10231134
    enzymeinhibitor11911838 11673765 10799660 10231134 11911838 10799660
    Moclobemide4-Chlor-N-(2-morpholinoethyl)benzamid (see all 11)71320-77-9targetinhibitor1705137 8875133 11752352
    enzymeinhibitor1705137 8875133 11752352 11752352
    SelegilineL-Deprenalin (see all 4)14611-51-9targetinhibitor19300583 17823646 16641841 17715422
    Almotriptan-- 181183-52-8enzymesubstrate12353056 12642466 15762767
    DopamineDopamin (see all 6)51-61-6enzymesubstrate15817751 18652859 20869994
    Flavin-Adenine Dinucleotide-- 146-14-5target--17139284 17016423 10592235
    FurazolidoneNitrofurazolidone (see all 3)67-45-8enzymeinhibitor12623758 2032659 10543364

    Selected Novoseek inferred chemical compound relationships for MAOA gene (see all 133)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    maoa 98.5 1084 17692293 (10), 19224413 (8), 11927135 (8), 15936529 (8) (see all 99)
    moclobemide 94.9 153 1546132 (5), 8612391 (3), 9663810 (3), 9174681 (3) (see all 99)
    clorgyline 91.8 98 1741773 (4), 9564606 (3), 1893487 (3), 8243537 (2) (see all 54)
    brofaromine 90.8 33 8430214 (4), 1967018 (2), 8313400 (2), 8313393 (2) (see all 22)
    befloxatone 90.4 36 8613928 (8), 12729662 (3), 7665725 (2), 9728902 (2) (see all 15)
    kynuramine 89.7 14 20504539 (1), 8990278 (1), 16139309 (1), 8443155 (1) (see all 12)
    toloxatone 88.5 10 1546145 (2), 1705137 (2), 1424410 (2), 8713690 (1) (see all 6)
    tyramine 85.5 68 17561096 (4), 8255365 (3), 8695909 (2), 7665725 (2) (see all 37)
    pirlindole 83.5 16 8953568 (3), 9564636 (2), 12781338 (2), 9272198 (2) (see all 7)
    1-phenylcyclopropylamine 81.4 3 15755651 (1), 15848762 (1)

    Find genes that share compounds with MAOA           About GenesLikeMe

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
    About This Section

    REFSEQ mRNAs for MAOA gene (2 alternative transcripts): 
    NM_000240.3  NM_001270458.1  

    Unigene Cluster for MAOA:

    Monoamine oxidase A
    Hs.183109  [show with all ESTs]
    Unigene Representative Sequence: NM_001270458
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000338702(uc004dfy.3 uc011mkw.2) ENST00000497485 ENST00000490604
    Block miRNA regulation of human, mouse, rat MAOA using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MAOA (see all 13):
    hsa-miR-3163 hsa-miR-495 hsa-miR-767-3p hsa-miR-7-2* hsa-miR-1324 hsa-miR-3065-5p hsa-miR-624* hsa-miR-29b-1*
    SwitchGear 3'UTR luciferase reporter plasmidMAOA 3' UTR sequence
    Inhib. RNA
    OriGene RNAi products in human, mouse, rat for MAOA
    Predesigned siRNA for gene silencing in human, mouse, rat MAOA
    OriGene clones in human, mouse for MAOA (see all 7)
    OriGene ORF clones in mouse, rat for MAOA
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: MAOA (NM_000240)
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAOA
    OriGene qPCR primer pairs and template standards for MAOA
    OriGene qSTAR qPCR primer pairs in human, mouse for MAOA
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MAOA
      QuantiTect SYBR Green Assays in human, mouse, rat MAOA
      QuantiFast Probe-based Assays in human, mouse, rat MAOA

    Additional mRNA sequence: 

    AK123241.1 AK223499.1 AK291769.1 AK293926.1 BC008064.2 BC044787.1 BT006651.1 M68840.1 

    11 DOTS entries:

    DT.95120451  DT.87015236  DT.101981844  DT.100025285  DT.100825058  DT.121278195  DT.100708824  DT.121278204 
    DT.95120454  DT.100718004  DT.70102839 

    Selected AceView cDNA sequences (see all 267):

    AI674356 AW511315 BU684121 R97085 CA444528 AA865791 BM923944 AA995668 
    F02245 AI076531 BQ717463 N29331 AW873998 BQ716421 AI890731 NM_000240 
    AW627528 BG534382 BF448960 N30236 H82430 CK818786 R86250 AI335934 

    GeneLoc Exon Structure

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GenesLikeMe, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MAOA expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    MAOA Expression
    About this image

    MAOA expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 13) fully expand
     Bone (Muscoskeletal System)    fully expand to see all 4 entries
             TGFbeta3+BMP7-induced chondrocytes
     Cartilage (Muscoskeletal System)    fully expand to see all 4 entries
             TGFbeta3+BMP7-induced chondrocytes
     Adipose (Muscoskeletal System)    fully expand to see all 3 entries
             White adipocyte-like cells
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebral Cortex
     Lung (Respiratory System)    fully expand to see all 2 entries
             Stem Bronchi
             Alveolar type II cells
    MAOA Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MAOA Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.183109

    UniProtKB/Swiss-Prot: AOFA_HUMAN, P21397
    Tissue specificity: Heart, liver, duodenum, blood vessels and kidney

        Pathway & Disease-focused RT2 Profiler PCR Arrays including MAOA: 
              Amino Acid Metabolism II in human mouse rat
              Drug Metabolism: Phase I Enzymes in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat

    OriGene qPCR primer pairs and template standards for MAOA
    OriGene qSTAR qPCR primer pairs in human, mouse for MAOA
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MAOA
    QuantiTect SYBR Green Assays in human, mouse, rat MAOA
    QuantiFast Probe-based Assays in human, mouse, rat MAOA
    In Situ
    Assay Products:

    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAOA

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for MAOA gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    Gene Description Human
    (Mus musculus)
    Mammalia Maoa1 , 5 monoamine oxidase A1, 5 85.19(n)1
      X (11.78 cM)5
    171611  NM_173740.31  NP_776101.31 
    (Gallus gallus)
    Aves MAOA6
    Gallus gallus monoamine oxidase A (MAOA), nuclear ...
    1 ↔ 1
    (Anolis carolinensis)
    Reptilia MAOA6
    monoamine oxidase A
    1 ↔ 1
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia LOC1004951981 amine oxidase [flavin-containing] A-like 68.62(n)
      100495198  XM_002932798.2  XP_002932844.2 
    (Danio rerio)
    Actinopterygii mao6
    monoamine oxidase
    1 → many
    9(34618751-34683759) ENSDARG00000023712

    ENSEMBL Gene Tree for MAOA (if available)
    TreeFam Gene Tree for MAOA (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to Build 68,Sets of similar genes according to GenesLikeMe)
    About This Section

    Paralogs for MAOA gene
    1 SIMAP similar gene for MAOA using alignment to 7 protein entries:     AOFA_HUMAN (see all proteins):

    Find genes that share paralogs with MAOA           About GenesLikeMe

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and 4UniProtKB, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    Polymorphic Variants from UniProtKB/Swiss-Prot
    AOFA_HUMAN, P21397: A polymorphism 1.2 kb upstream of the MAOA coding sequences consists of a 30-bp repeated sequence
    present in 3, 3.5, 4, or 5 copies. The polymorphism affect transcriptional activity of the MAOA gene promoter.
    Alleles with 3.5 or 4 copies of the repeat sequence are transcribed 2 to 10 times more efficiently than those
    with 3 or 5 copies of the repeat

    Selected SNPs for MAOA (see all 1109)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    Chr X posSequence#AA
    A breast cancer sample4--see VAR_0365452 D E mis40--------
    Cpathogenic143591031(+) TAATTC/TAGCGG 4 Q * stg10--------
    --43512260(+) AGGATC/TGAGGC 2 -- us2k10--------
    C,F--43512290(+) caGTCA/GGCCTC 2 -- us2k12Minor allele frequency- G:0.00WA CSA 3
    C,F--43512293(+) TCGGCT/CTCAGC 2 -- us2k12Minor allele frequency- C:0.00WA CSA 3
    C,F,A,H--43512302(+) GCAGCC/GTTGTC 2 -- us2k110Minor allele frequency- G:0.32NA WA CSA 19
    --43512369(+) TTTTTC/TCTACC 2 -- us2k10--------
    C,F--43512512(+) ACATTC/TGTCAG 2 -- us2k11Minor allele frequency- T:0.00CSA 1
    --43512744(+) GATTTC/TTTCAT 2 -- us2k10--------
    --43512882(+) CATATG/TTCTTT 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for MAOA (43515409 - 43606068 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for MAOA:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv21483CNV Gain19812545
    nsv517873CNV Gain19592680

    Human Gene Mutation Database (HGMD): MAOA
    Locus Specific Mutation Databases (LSDB): MAOA

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MAOA

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB, Sets of similar genes according to GenesLikeMe)
    About This Section

    OMIM gene information: 309850   
    OMIM disorders: 300615  
    UniProtKB/Swiss-Prot: AOFA_HUMAN, P21397
  • Brunner syndrome (BRUNS) [MIM:300615]: A form of X-linked non-dysmorphic mild mental retardation. Male
    patients are affected by borderline mental retardation and exhibit abnormal behavior, including disturbed
    regulation of impulsive aggression. Obligate female carriers have normal intelligence and behavior. Note=The
    disease is caused by mutations affecting the gene represented in this entry

  • Selected diseases for MAOA (see all 31):    
    About MalaCards
    brunner syndrome    avoidant personality disorder    social phobia    maoa-related behavior disorders
    antisocial personality disorder    substance abuse    personality disorder    paranoid schizophrenia
    serotonin syndrome    melancholia    postpartum depression    conduct disorder
    borderline personality disorder    norrie disease    agoraphobia    lesch-nyhan syndrome
    endogenous depression    pathological gambling    hepatic encephalopathy    oppositional defiant disorder

    13 inferred disease relationships from the University of Copenhagen DISEASES database for MAOA:
    Parkinson's disease     Anxiety disorder     Antisocial personality disorder     Conduct disorder
    Attention deficit hyperactivity disorder     Endogenous depression     Schizophrenia     Toxic encephalopathy
    Melancholia     Alcohol dependence     Avoidant personality disorder     Borderline personality disorder

    Find genes that share disorders with MAOA           About GenesLikeMe

    Selected Novoseek inferred disease relationships for MAOA gene (see all 76)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    antisocial behavior 75.8 57 17008143 (4), 18023041 (3), 19120058 (3), 10359483 (2) (see all 20)
    borderline mental retardation 74.5 3 8776592 (1), 9326944 (1), 8613523 (1)
    antisocial personality disorder 65.4 32 12824808 (5), 17007976 (3), 10049583 (2), 20175604 (2) (see all 10)
    major depression 64.7 65 18337637 (4), 10564737 (4), 17884271 (4), 9179504 (3) (see all 28)
    aggressive behavior 63 36 15817751 (3), 15211623 (2), 18996506 (2), 17657171 (2) (see all 22)
    crisis hypertensive 59.4 7 17554106 (1), 9829163 (1), 14697896 (1), 19527191 (1)
    attention-deficit hyperactivity disorder 55.8 15 17230031 (2), 8862874 (1), 12140786 (1), 19309535 (1) (see all 13)
    bipolar disorder 53.7 47 10402508 (4), 8776592 (3), 9342194 (3), 16958037 (3) (see all 21)
    phobia social 53.6 8 8313403 (2), 10361959 (1), 8619339 (1), 9534836 (1) (see all 5)
    parkinson disease 52.5 32 7593732 (3), 17044053 (2), 8358501 (2), 9579294 (2) (see all 22)

    Genetic Association Database (GAD): MAOA
    Human Genome Epidemiology (HuGE) Navigator: MAOA (290 documents)

    Export disorders for MAOA gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MAOA gene, integrated from 10 sources (see all 1107) (see top 10):
    (articles sorted by number of sources associating them with MAOA)

    1. A non-additive interaction of a functional MAO-A VNTR and testosterone predicts antisocial behavior. (PubMed id 17429405)1, 4, 7, 9 SjAPberg R.L....Goldman D. (Neuropsychopharmacology 2008)
    2. Early trauma and increased risk for physical aggression during adulthood: the moderating role of MAOA genotype. (PubMed id 17534436)1, 4, 9 Frazzetto G....Troisi A. (PLoS ONE 2007)
    3. A promoter polymorphism in the monoamine oxidase A gene is associated with the pineal MAOA activity in Alzheimer's disease patients. (PubMed id 17692293)1, 4, 9 Wu Y.H....Swaab D.F. (Brain Res. 2007)
    4. [Association study of the polymorphisms of monoamine oxidase A genes with schizophrenia]. (PubMed id 17680543)1, 4, 9 Shi Y.Z....Lou B.Y. (Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2007)
    5. Three-dimensional structure of human monoamine oxidase A (MAO A): relation to the structures of rat MAO A and human MAO B. (PubMed id 16129825)1, 2, 9 De Colibus L.... Mattevi A. (Proc. Natl. Acad. Sci. U.S.A. 2005)
    6. Analysis of monoamine oxidase A (MAOA) promoter polymorphism in Finnish male alcoholics. (PubMed id 11927135)1, 4, 9 Saito T....Tiihonen J. (Psychiatry Res 2002)
    7. Structure of human monoamine oxidase A at 2.2-A resolution: the control of opening the entry for substrates/inhibitors. (PubMed id 18391214)1, 2, 9 Son S.-Y.... Tsukihara T. (Proc. Natl. Acad. Sci. U.S.A. 2008)
    8. Effects of MAOA-genotype, alcohol consumption, and aging on violent behavior. (PubMed id 19120058)1, 4, 9 Tikkanen R....Virkkunen M. (Alcohol. Clin. Exp. Res. 2009)
    9. The development of peripartum depressive symptoms is associated with gene polymorphisms of MAOA, 5-HTT and COMT. (PubMed id 19625011)1, 4, 9 Doornbos B....Korf J. (amp 2009)
    10. MAOA gene polymorphisms and response to mirtazapine in major depression. (PubMed id 19382113)1, 4, 9 Tzeng D.S....Yang C.Y. (Hum Psychopharmacol 2009)
    11. Monoamine oxidase A genotype predicts human serotonin 1A receptor availability in vivo. (PubMed id 18971477)1, 4, 9 Mickey B.J....Zubieta J.K. (J. Neurosci. 2008)
    12. MAOA, maltreatment, and gene-environment interaction predicting children's mental health: new evidence and a meta-analysis. (PubMed id 16801953)1, 4, 9 Kim-Cohen J....Moffitt T.E. (Mol. Psychiatry 2006)
    13. MAOA promoter polymorphism and attention deficit hyperactivity disorder (ADHD) in indian children. (PubMed id 16856146)1, 4, 9 Das M....Mukhopadhyay K. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2006)
    14. Cluster B personality disorders are associated with allelic variation of monoamine oxidase A activity. (PubMed id 15870836)1, 4, 9 Jacob C.P....Lesch K.P. (Neuropsychopharmacology 2005)
    15. Telomeric length varies with age and polymorphisms of the MAOA gene promoter in peripheral blood cells obtained from a community in Taiwan. (PubMed id 15722955)1, 4, 9 Lung F.W....Shu B.C. (Psychiatr. Genet. 2005)
    16. Gene-gene interaction between MAOA and COMT in suicidal behavior. (PubMed id 15936529)1, 4, 9 De Luca V....Kennedy J.L. (Neurosci. Lett. 2005)
    17. Association of variations in monoamine oxidases A and B with Parkinson's disease subgroups. (PubMed id 14962671)1, 4, 9 Parsian A....Perlmutter J.S. (Genomics 2004)
    18. Analysis of monoamine oxidase A (MAO-A) promoter polymorphism in male heroin-dependent subjects: behavioural and personality correlates. (PubMed id 15088154)1, 4, 9 Gerra G....Donnini C. (J Neural Transm 2004)
    19. A regulatory monoamine oxidase a promoter polymorphism and personality traits. (PubMed id 12566936)1, 4, 9 Garpenstrand H....JAPnsson E.G. (Neuropsychobiology 2002)
    20. No association of the MAOA gene with alcoholism among Han Chinese males in Taiwan. (PubMed id 11999895)1, 4, 9 Lu R.B....Shih J.C. (amp 2002)
    21. Promoter organization and activity of human monoamine oxidase (MAO) A and B genes. (PubMed id 1432104)1, 2, 9 Zhu Q.S.... Shih J.C. (J. Neurosci. 1992)
    22. Structure of the human gene for monoamine oxidase type A. (PubMed id 1886775)1, 2, 9 Chen Z.-Y.... Hsu Y.-P.P. (Nucleic Acids Res. 1991)
    23. Monoamine oxidase A and childhood adversity as risk factors for conduct disorder in females. (PubMed id 18752729)1, 4, 9 Prom-Wormley E.C....Silberg J.L. (Psychol Med 2009)
    24. Association analysis of monoamine oxidase A gene and bipolar affective disorder in Han Chinese. (PubMed id 18501009)1, 4, 9 Lin Y.M....Sun H.S. (Behav Brain Funct 2008)
    25. Possible interaction between MAOA and DRD2 genes associated with antisocial alcoholism among Han Chinese men in Taiwan. (PubMed id 17007976)1, 4, 9 Wang T.J....Lu R.B. (amp 2007)
    26. The monoamine oxidase A (MAO-A) gene, family function and maltreatment as predictors of destructive behaviour during male adolescent alcohol consumption. (PubMed id 17298646)1, 4, 9 Nilsson K.W....Oreland L. (Addiction 2007)
    27. MAOA and the &quot;cycle of violence:&quot; childhood abuse and neglect, MAOA genotype, and risk for violent and antisocial behavior. (PubMed id 16814261)1, 4, 9 Widom C.S. and Brzustowicz L.M. (Biol. Psychiatry 2006)
    28. A functional polymorphism in the MAOA gene promoter (MAOA-LPR) predicts central dopamine function and body mass index. (PubMed id 16770335)1, 4, 9 Ducci F....Goldman D. (Mol. Psychiatry 2006)
    29. Monoamine oxidase A (MAOA) and antisocial behaviors in the presence of childhood and adolescent maltreatment. (PubMed id 15806601)1, 4, 9 Haberstick B.C....Hewitt J.K. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2005)
    30. Association analysis of monoamine oxidase A and attention deficit hyperactivity disorder. (PubMed id 12497620)1, 4, 9 Lawson D.C....Thapar A. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2003)
    31. Meta-analysis of the association between the monoamine oxidase-A gene and mood disorders. (PubMed id 20010318)1, 4, 9 Fan M....Zhang J. (Psychiatr. Genet. 2010)
    32. Association of VNTR polymorphisms in the MAOA promoter and DRD4 exon 3 with heroin dependence in male Chinese addicts. (PubMed id 20218801)1, 4, 9 Chien C.C....Lung F.W. (World J. Biol. Psychiatry 2010)
    33. Monoamine oxidase A gene (MAOA) predicts behavioral aggression following provocation. (PubMed id 19168625)1, 4, 9 McDermott R....Johnson D.D. (Proc. Natl. Acad. Sci. U.S.A. 2009)
    34. Association between monoamine oxidase (MAO)-A gene variants and schizophrenia in a Chinese population. (PubMed id 19573521)1, 4, 9 Qiu H.T....Zhang X.Y. (Brain Res. 2009)
    35. Neither single-marker nor haplotype analyses support an association between monoamine oxidase A gene and bipolar disorder. (PubMed id 18437281)1, 4, 9 Huang S.Y....Lu R.B. (Eur Arch Psychiatry Clin Neurosci 2008)
    36. Differential association between MAOA, ADHD and neuropsychological functioning in boys and girls. (PubMed id 18726986)1, 4, 9 Rommelse N.N....Franke B. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2008)
    37. Interaction between a functional MAOA locus and childhood sexual abuse predicts alcoholism and antisocial personality disorder in adult women. (PubMed id 17592478)1, 4, 9 Ducci F....Goldman D. (Mol. Psychiatry 2008)
    38. Sexually dimorphic effects of four genes (COMT, SLC6A2, MAOA, SLC6A4) in genetic associations of ADHD: a preliminary study. (PubMed id 18937309)1, 4, 9 Biederman J....Faraone S.V. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2008)
    39. Association of MAO-A variant with complicated grief in major depression. (PubMed id 18337637)1, 4, 9 Kersting A....Domschke K. (Neuropsychobiology 2007)
    40. Convergent genetic modulation of the endocrine stress response involves polymorphic variations of 5-HTT, COMT and MAOA. (PubMed id 17453062)1, 4, 9 Jabbi M....den Boer J.A. (Mol. Psychiatry 2007)
    41. The MAOA promoter polymorphism, disruptive behavior disorders, and early onset substance use disorder: gene-environment interaction. (PubMed id 18075472)1, 4, 9 Vanyukov M.M....Ferrell R.E. (Psychiatr. Genet. 2007)
    42. Childhood maltreatment, subsequent antisocial behavior, and the role of monoamine oxidase A genotype. (PubMed id 17008143)1, 4, 9 Huizinga D....Hewitt J.K. (Biol. Psychiatry 2006)
    43. No allele variation of the MAOA gene promoter in male Chinese subjects with attention deficit hyperactivity disorder. (PubMed id 17230031)1, 4, 9 Lung F.W....Kao W.T. (Neuropsychobiology 2006)
    44. [Association of functional genes polymorphisms of key enzymes in the metabolism of biogenic amines with paranoid schizophrenia susceptibility and the influence of these polymorphisms on PANSS results in antipsychotic treatment]. (PubMed id 17217235)1, 4, 9 Tybura P....Samochowiec J. (Psychiatr. Pol. 2006)
    45. Monoamine oxidases A and B gene polymorphisms in migraine patients. (PubMed id 15694196)1, 4, 9 Filic V....Jernej B. (J. Neurol. Sci. 2005)
    46. No association between monoamine oxidase A promoter polymorphism and personality traits in Japanese females. (PubMed id 16139427)1, 4, 9 Hakamata Y....Inada T. (Neurosci. Lett. 2005)
    47. Polymorphisms in the MAOA, MAOB, and COMT genes and aggressive behavior in schizophrenia. (PubMed id 15211623)1, 4, 9 Zammit S....Owen M.J. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2004)
    48. Neither antisocial personality disorder nor antisocial alcoholism is associated with the MAO-A gene in Han Chinese males. (PubMed id 12824808)1, 4, 9 Lu R.B....Shih J.C. (Alcohol. Clin. Exp. Res. 2003)
    49. Association analysis of MAOA and COMT with neuroticism assessed by peers. (PubMed id 12815746)1, 4, 9 Eley T.C....Craig I. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2003)
    50. Human monoamine oxidase A and B genes exhibit identical exon-intron organization. (PubMed id 2023912)1, 2, 9 Grimsby J.... Shih J.C. (Proc. Natl. Acad. Sci. U.S.A. 1991)
    51. MAOA is associated with methylphenidate improvement of oppositional symptoms in boys with attention deficit hyperactivity disorder. (PubMed id 19309535)1, 4, 9 GuimarALes A.P....Hutz M.H. (Int. J. Neuropsychopharmacol. 2009)
    52. Reduced amygdala-prefrontal coupling in major depression: association with MAOA genotype and illness severity. (PubMed id 18544183)1, 4, 9 Dannlowski U....Suslow T. (Int. J. Neuropsychopharmacol. 2009)
    53. Negative emotionality: monoamine oxidase B gene variants modulate personality traits in healthy humans. (PubMed id 19657584)1, 4, 9 Dlugos Wit H. (J Neural Transm 2009)
    54. Further evidence of MAO-A gene variants associated with bipolar disorder. (PubMed id 16958037)1, 4, 9 MA1ller D.J....Kennedy J.L. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2007)
    55. Monoamine oxidase-A polymorphisms might modify the association between the dopamine D2 receptor gene and alcohol dependence. (PubMed id 17476365)1, 4, 9 Huang S.Y....Lu R.B. (amp 2007)
    56. Polymorphisms of dopamine degradation enzyme (COMT and MAO) genes and tardive dyskinesia in patients with schizophrenia. (PubMed id 15261699)1, 4, 9 Matsumoto C....Nakamura J. (Psychiatry Res 2004)
    57. Association of a MAOA gene variant with generalized anxiety disorder, but not with panic disorder or major depression. (PubMed id 12555227)1, 4, 9 Tadic A....Dahmen N. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2003)
    58. Functional variation in promoter region of monoamine oxidase A and subtypes of alcoholism: haplotype analysis. (PubMed id 12555234)1, 4, 9 Parsian A....Zhang Z.H. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2003)
    59. No evidence of an association between a functional monoamine oxidase a gene polymorphism and completed suicides. (PubMed id 11920860)1, 4, 9 Ono H....Maeda K. (Am. J. Med. Genet. 2002)
    60. MAO-A and COMT polymorphisms and gene effects in narcolepsy. (PubMed id 11443519)1, 4, 9 Dauvilliers Y....Tafti M. (Mol. Psychiatry 2001)
    61. Serotonin genes and gene-gene interactions in borderline personality disorder in a matched case-control study. (PubMed id 19032968)1, 4, 9 Ni X....Kennedy J.L. (amp 2009)
    62. Psychopathy trait scores in adolescents with childhood ADHD: the contribution of genotypes affecting MAOA, 5HTT and COMT activity. (PubMed id 19829167)1, 4, 9 Fowler T....Thapar A. (Psychiatr. Genet. 2009)
    63. Serotonin transporter (5-HTTLPR) and monoamine oxidase (MAOA) promoter polymorphisms in women with severe alcoholism. (PubMed id 18827956)1, 4, 9 Gokturk C....Hallman J. (Arch Womens Ment Health 2008)
    64. The MAO-A gene, platelet MAO-B activity and psychosocial environment in adolescent female alcohol-related problem behaviour. (PubMed id 18029114)1, 4, 9 Nilsson K.W....Oreland L. (Drug Alcohol Depend 2008)
    65. A community-based study of cigarette smoking behavior in relation to variation in three genes involved in dopamine metabolism: Catechol-O-methyltransferase (COMT), dopamine beta-hydroxylase (DBH) and monoamine oxidase-A (MAO-A). (PubMed id 18486967)1, 4, 9 Shiels M.S....Alberg A.J. (Prev Med 2008)
    66. Meta-study on association between the monoamine oxidase A gene (MAOA) and schizophrenia. (PubMed id 17894408)1, 4, 9 Li D. and He L. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2008)
    67. Gene-gene interaction analysis of personality traits in a Japanese population using an electrochemical DNA array chip analysis. (PubMed id 17208375)1, 4, 9 Urata T....Inada T. (Neurosci. Lett. 2007)
    68. Combined analysis of association between personality traits and three functional polymorphisms in the tyrosine hydroxylase, monoamine oxidase A, and catechol-O-methyltransferase genes. (PubMed id 16360899)1, 4, 9 Tochigi M....Sasaki T. (Neurosci. Res. 2006)
    69. Obesity is associated with genetic variants that alter dopamine availability. (PubMed id 16674552)1, 4, 9 Need A.C....Goldstein D.B. (Ann. Hum. Genet. 2006)
    70. Family-based case-control study of MAOA and MAOB polymorphisms in Parkinson disease. (PubMed id 17044053)1, 4, 9 Kang S.J....Martin E.R. (Mov. Disord. 2006)
    71. Association between monoamine oxidase gene polymorphisms and smoking behaviour in Chinese males. (PubMed id 16207390)1, 4, 9 Jin Y....Li L. (Int. J. Neuropsychopharmacol. 2006)
    72. Serotonin transporter, tryptophan hydroxylase, and monoamine oxidase A gene polymorphisms in premenstrual dysphoric disorder. (PubMed id 17026953)1, 4, 9 Magnay J.L....O'Brien S. (Am. J. Obstet. Gynecol. 2006)
    73. Association of MAO A polymorphism and alcoholism in Brazilian females. (PubMed id 15900229)1, 4, 9 Guindalini C....Zatz M. (Psychiatr. Genet. 2005)
    74. Association analysis between a functional polymorphism in the monoamine oxidase A gene promoter and severe mood disorders. (PubMed id 15564894)1, 4, 9 GutiAcrrez B....FaA+anA!s L. (Psychiatr. Genet. 2004)
    75. MAO-A gene polymorphisms are associated with major depression and sleep disturbance in males. (PubMed id 15486489)1, 4, 9 Du L....Hrdina P.D. (Neuroreport 2004)
    76. Pharmacogenetics of lithium prophylaxis in mood disorders: analysis of COMT, MAO-A, and Gbeta3 variants. (PubMed id 11992559)1, 4, 9 Serretti A....Smeraldi E. (Am. J. Med. Genet. 2002)
    77. Additional evidence that genetic variation of MAO-A gene supports a gender subtype in obsessive-compulsive disorder. (PubMed id 11353450)1, 4, 9 Camarena B....Nicolini H. (Am. J. Med. Genet. 2001)
    78. Polymorphic MAO-A and 5-HT-transporter genes: analysis of interactions in panic disorder. (PubMed id 12607224)1, 4, 9 Sand P....Deckert J. (World J. Biol. Psychiatry 2000)
    79. Association study of the serotoninergic system in migraine in the Spanish population. (PubMed id 19455600)1, 4, 9 Corominas R....Cormand B. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2010)
    80. Gene-gene interaction between COMT and MAOA potentially predicts the intelligence of attention-deficit hyperactivity disorder boys in China. (PubMed id 19941049)1, 4, 9 Qian Q.J....Faraone S.V. (Behav. Genet. 2010)
    81. Frequencies of genetic polymorphisms related to triptans metabolism in chronic migraine. (PubMed id 20213484)1, 4, 9 Gentile G....Martelletti P. (J Headache Pain 2010)
    82. Associations between polymorphisms in dopamine neurotransmitter pathway genes and pain response in healthy humans. (PubMed id 19796878)1, 4, 9 Treister R....Eisenberg E. (Pain 2009)
    83. No evidence for association between an MAOA functional polymorphism and susceptibility to Parkinson's disease. (PubMed id 19267171)1, 4, 9 Williams-Gray C....Barker R.A. (J. Neurol. 2009)
    84. [Association study of intelligence of attention deficit hyperactivity disorder children in China]. (PubMed id 19727210)1, 4, 9 Qian Q.J....Liu L. (Beijing Da Xue Xue Bao 2009)
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    86. Resequencing of serotonin-related genes and association of tagging SNPs to citalopram response. (PubMed id 19077664)1, 4, 9 Peters E.J....Hamilton S.P. (Pharmacogenet. Genomics 2009)
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    89. MAOA-uVNTR polymorphism may modify the protective effect of ALDH2 gene against alcohol dependence in antisocial personality disorder. (PubMed id 19302089)1, 4, 9 Lee S.Y....Lu R.B. (Alcohol. Clin. Exp. Res. 2009)
    90. A polymorphism of the MAOA gene is associated with emotional brain markers and personality traits on an antisocial index. (PubMed id 19194374)1, 4, 9 Williams L.M....Gordon E. (Neuropsychopharmacology 2009)
    91. Candidate gene studies of ADHD: a meta-analytic review. (PubMed id 19506906)1, 4, 9 Gizer I.R....Waldman I.D. (Hum. Genet. 2009)
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    93. The interleukin-6, serotonin transporter, and monoamine oxidase A genes and endurance performance during the South African Ironman Triathlon. (PubMed id 19935847)1, 4, 9 de Milander L....Collins M. (Appl Physiol Nutr Metab 2009)
    94. Association of dopamine transporter and monoamine oxidase molecular polymorphisms with sudden infant death syndrome and stillbirth: new insights into the serotonin hypothesis. (PubMed id 18810510)1, 4, 9 Filonzi L....Marzano F.N. (Neurogenetics 2009)
    95. Interactions between genotype and depressive symptoms on obesity. (PubMed id 19337825)1, 4, 9 Fuemmeler B.F....Ashley-Koch A.E. (Behav. Genet. 2009)
    96. MAO-A and COMT genotypes as possible regulators of perinatal serotonergic symptoms after in utero exposure to SSRIs. (PubMed id 19223155)1, 4, 9 Hilli J....Laine K. (Eur Neuropsychopharmacol 2009)
    97. A common variant in DRD3 gene is associated with risperidone-induced extrapyramidal symptoms. (PubMed id 19506579)1, 4, 9 GassA^ P....Lafuente A. (Pharmacogenomics J. 2009)
    98. Brief report: aggression and stereotypic behavior in males with fragile X syndrome--moderating secondary genes in a &quot;single gene&quot; disorder. (PubMed id 17340199)1, 4, 9 Hessl D....Hagerman R.J. (J Autism Dev Disord 2008)
    99. Hyperserotonemia in autism: the potential role of 5HT-related gene variants. (PubMed id 18405062)1, 4, 9 HraniloviA8 D....Jernej B. (Coll Antropol 2008)
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    102. Interactions between genotype and retrospective ADHD symptoms predict lifetime smoking risk in a sample of young adults. (PubMed id 18188752)1, 4, 9 McClernon F.J....Ashley-Koch A.E. (amp 2008)
    103. Lipid levels are associated with a regulatory polymorphism of the monoamine oxidase-A gene promoter (MAOA-uVNTR). (PubMed id 18227761)1, 4, 9 Brummett B.H....Williams R.B. (Med. Sci. Monit. 2008)
    104. HPA axis function in male caregivers: effect of the monoamine oxidase-A gene promoter (MAOA-uVNTR). (PubMed id 18639608)1, 4, 9 Brummett B.H....Williams R.B. (Biol Psychol 2008)
    105. 5-HT2C receptor and MAO-A interaction analysis: no association with suicidal behaviour in bipolar patients. (PubMed id 18504633)1, 4, 9 De Luca V....Kennedy J.L. (Eur Arch Psychiatry Clin Neurosci 2008)
    106. Monoamine oxidase A-uVNTR genotype affects limbic brain activity in response to affective facial stimuli. (PubMed id 18388730)1, 4, 9 Lee B.T. and Ham B.J. (Neuroreport 2008)
    107. ADHD and Disruptive Behavior scores - associations with MAO-A and 5-HTT genes and with platelet MAO-B activity in adolescents. (PubMed id 18430257)1, 4, 9 Malmberg K....Larsson J.O. (BMC Psychiatry 2008)
    108. Association study of MAO-A and DRD4 genes in schizophrenic patients with aggressive behavior. (PubMed id 17657171)1, 4, 9 Fresan A....Nicolini H. (Neuropsychobiology 2007)
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    111. The MAOA T941G polymorphism and short-term treatment response to mirtazapine and paroxetine in major depression. (PubMed id 17192957)1, 4, 9 TadiA8 A....Szegedi A. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2007)
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    122. Genetic polymorphisms in monoamine neurotransmitter systems show only weak association with acute post-surgical pain in humans. (PubMed id 16848906)1, 4, 9 Kim H....Dionne R.A. (Mol Pain 2006)
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    127. Polymorphisms in genes regulating the HPA axis associated with empirically delineated classes of unexplained chronic fatigue. (PubMed id 16610949)1, 4, 9 Smith A.K....Rajeevan M.S. (Pharmacogenomics 2006)
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    129. Monoamine oxidase-a genetic variations influence brain activity associated with inhibitory control: new insight into the neural correlates of impulsivity. (PubMed id 16202396)1, 4, 9 Passamonti L....Quattrone A. (Biol. Psychiatry 2006)
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    351. MAOA promoter methylation and susceptibility to carotid atherosclerosis: role of familial factors in a monozygotic twin sample. (PubMed id 23116433)1 Zhao J....Vaccarino V. (BMC Med. Genet. 2012)
    352. Monoamine oxidase inhibitory activity in tobacco smoke varies with tobacco type. (PubMed id 21636610)7 Lewis A.J....Miller J.H. (Tob Control 2012)
    353. Working memory brain activity and capacity link MAOA polymorphism to aggressive behavior during development. (PubMed id 22832821)1 Ziermans T....Klingberg T. (Transl Psychiatry 2012)
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    357. Monoamine oxidase A down-regulation contributes to high metanephrine concentration in pheochromocytoma. (PubMed id 22569243)1 Grouzmann E....Abid K. (J. Clin. Endocrinol. Metab. 2012)
    358. Genetically based reduced MAOA and COMT functioning is associated with the cortisol stress response: a replication study. (PubMed id 21912392)1 Bouma E.M....Oldehinkel A.J. (Mol. Psychiatry 2012)
    359. The c.1460C&gt;T polymorphism of MAO-A is associated with the risk of depression in postmenopausal women. (PubMed id 22619623)1 SA8opieA8 R....JagodziA8ski P.P. (ScientificWorldJournal 2012)
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    363. Developmental changes in human dopamine neurotransmission: cortical receptors and terminators. (PubMed id 22336227)1 Rothmond D.A....Webster M.J. (BMC Neurosci 2012)
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    370. Association study between the dopamine-related candidate gene polymorphisms and ADHD among Saudi Arabia population via PCR technique. (PubMed id 23076524)1 El-Tarras A.E....Sabry A.M. (Mol. Biol. Rep. 2012)
    371. Evidence that the methylation state of the monoamine oxidase A (MAOA) gene predicts brain activity of MAO A enzyme in healthy men. (PubMed id 22948232)1 Shumay E....Fowler J.S. (Epigenetics 2012)
    372. Association between a functional polymorphism in the MAOA gene and sudden infant death syndrome. (PubMed id 22351881)1 Klintschar M. and Heimbold C. (Pediatrics 2012)
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    374. Serotonin transporter role in identifying similarities between SIDS and idiopathic ALTE. (PubMed id 22711722)1 Filonzi L....Nonnis Marzano F. (Pediatrics 2012)
    375. MAOA, MTHFR, and TNF-I^ genes polymorphisms and personality traits in the pathogenesis of migraine. (PubMed id 22193458)1 Ishii M....Kiuchi Y. (Mol. Cell. Biochem. 2012)
    376. The monoamine oxidase A gene promoter repeat and prostate cancer risk. (PubMed id 22473857)1 White T.A....Nelson P.S. (Prostate 2012)
    377. A^H kinetic isotope effects and pH dependence of catalysis as mechanistic probes of rat monoamine oxidase A: comparisons with the human enzyme. (PubMed id 21819071)1 Wang J. and Edmondson D.E. (Biochemistry 2011)
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    380. Serotonergic modulation in executive functioning: linking genetic variations to working memory performance. (PubMed id 21983350)1 Enge S....Strobel A. (Neuropsychologia 2011)
    381. Molecular-genetic correlates of self-harming behaviors in eating-disordered women: findings from a combined Canadian-German sample. (PubMed id 20869421)1 Steiger H....Bachetzky N. (amp 2011)
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    383. Parkin degrades estrogen-related receptors to limit the expression of monoamine oxidases. (PubMed id 21177257)1 Ren Y....Feng J. (Hum. Mol. Genet. 2011)
    384. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
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    391. Postpartum depression symptoms: a case-control study on monoaminergic functional polymorphisms and environmental stressors. (PubMed id 21099450)1 Comasco E....Skalkidou A. (Psychiatr. Genet. 2011)
    392. Confirmed association between monoamine oxidase A molecular polymorphisms and Sudden Infant Death Syndrome. (PubMed id 20820831)1 Filonzi L....Marzano F.N. (Neurogenetics 2011)
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    395. Valproic acid induces monoamine oxidase A via Akt/forkhead box O1 activation. (PubMed id 21775495)1 Wu J.B. and Shih J.C. (Mol. Pharmacol. 2011)
    396. Psychopathy, PCL-R, and MAOA genotype as predictors of violent reconvictions. (PubMed id 20850185)1 Tikkanen R....Virkkunen M. (Psychiatry Res 2011)
    397. Prefrontal cortex lesions and MAO-A modulate aggression in penetrating traumatic brain injury. (PubMed id 21422455)1 Pardini M....Grafman J. (Neurology 2011)
    398. Type A monoamine oxidase regulates life and death of neurons in neurodegeneration and neuroprotection. (PubMed id 21971004)1 Naoi M....Akao Y. (Int. Rev. Neurobiol. 2011)
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    400. Gene x disease interaction on orbitofrontal gray matter in cocaine addiction. (PubMed id 21383264)1 Alia-Klein N....Goldstein R.Z. (Arch. Gen. Psychiatry 2011)
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    403. Monoamine oxidase and semicarbazide-sensitive amine oxidase kinetic analysis in mesenteric arteries of patients with type 2 diabetes. (PubMed id 21114364)1 Nunes S.F....Caramona M.M. (Physiol Res 2011)
    404. Bimodal distribution of RNA expression levels in human skeletal muscle tissue. (PubMed id 21299892)1 Mason C.C....Bogardus C. (BMC Genomics 2011)
    405. Up-regulation of the isoenzymes MAO-A and MAO-B in the human basal ganglia and pons in Huntington's disease revealed by quantitative enzyme radioautography. (PubMed id 21075085)1 Richards G....Saura J. (Brain Res. 2011)
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    407. Genetic susceptibility for individual cooperation preferences: the role of monoamine oxidase A gene (MAOA) in the voluntary provision of public goods. (PubMed id 21698196)1 Mertins V....Meyer J. (PLoS ONE 2011)
    408. Monoamine oxidases (MAO) in the pathogenesis of heart failure and ischemia/reperfusion injury. (PubMed id 20869994)7 Kaludercic N....Paolocci N. (Biochim. Biophys. Acta 2011)
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    411. MAO A VNTR polymorphism and amygdala volume in healthy subjects. (PubMed id 21236646)1 Cerasa A....Spalletta G. (Psychiatry Res 2011)
    412. MAOA-L carriers are better at making optimal financial decisions under risk. (PubMed id 21147794)1 Frydman C....Rangel A. (Proc. Biol. Sci. 2011)
    413. MAOA, DBH, and SLC6A4 variants in CHARGE: a case-control study of autism spectrum disorders. (PubMed id 21538940)1 Tassone F....Hertz-Picciotto I. (Autism Res 2011)
    414. Cognitive effects of genetic variation in monoamine neurotransmitter systems: a population-based study of COMT, MAOA, and 5HTTLPR. (PubMed id 21302344)1 Barnett J.H....Jones P.B. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2011)
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    417. Search for association between suicide and 5-HTT, MAOA and DAT polymorphism in Polish males. (PubMed id 21516943)1 Linkowska K....Grzybowski T. (Arch Med Sadowej Kryminol 2010)
    418. Targeting monoamine oxidase A in advanced prostate cancer. (PubMed id 20204405)1 Flamand V....Peehl D.M. (J. Cancer Res. Clin. Oncol. 2010)
    419. Effects of age and MAOA genotype on the neural processing of social rejection. (PubMed id 20497231)1 Sebastian C.L....Blakemore S.J. (Genes Brain Behav. 2010)
    420. Deletion of MAOA and MAOB in a male patient causes severe developmental delay, intermittent hypotonia and stereotypical hand movements. (PubMed id 20485326)1 Whibley A....Raymond F.L. (Eur. J. Hum. Genet. 2010)
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    422. Genetic determinants of time perception mediated by the serotonergic system. (PubMed id 20862259)1 Sysoeva O.V....Wackermann J. (PLoS ONE 2010)
    423. Mirtazapine abolishes hyperthermia in an animal model of serotonin syndrome. (PubMed id 20655983)7 Shioda K....Kato S. (Neurosci. Lett. 2010)
    424. MAOA interacts with the ALDH2 gene in anxiety-depression alcohol dependence. (PubMed id 20477771)1 Lee S.Y....Lu R.B. (Alcohol. Clin. Exp. Res. 2010)
    425. A population-specific HTR2B stop codon predisposes to severe impulsivity. (PubMed id 21179162)2 Bevilacqua L.... Goldman D. (Nature 2010)
    426. Harsh discipline, childhood sexual assault, and MAOA genotype: an investigation of main and interactive effects on diverse clinical externalizing outcomes. (PubMed id 20364435)1 Derringer J....Iacono W.G. (Behav. Genet. 2010)
    427. Identification and characterization of putative methylation targets in the MAOA locus using bioinformatic approaches. (PubMed id 20421737)1 Shumay E. and Fowler J.S. (Epigenetics 2010)
    428. Zonisamide: a new drug for Parkinson's disease. (PubMed id 20502722)7 Murata M. (Drugs Today 2010)
    429. MAOA T941G polymorphism and the time course of emotional recovery following unpleasant pictures. (PubMed id 20374544)1 Larson C.L....Robinson J.S. (Psychophysiology 2010)
    430. Long-term administration of monoamine oxidase inhibitors alters the firing rate and pattern of dopamine neurons in the ventral tegmental area. (PubMed id 18700056)7 Chenu F....Blier P. (Int. J. Neuropsychopharmacol. 2009)
    431. Antidepressant phenelzine alters differentiation of cultured human and mouse preadipocytes. (PubMed id 19201819)7 Chiche F....FA"ve B. (Mol. Pharmacol. 2009)
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    434. A Bayesian approach to gene-gene and gene-environment interactions in chronic fatigue syndrome. (PubMed id 19102713)4 Lin E. and Hsu S.Y. (Pharmacogenomics 2009)
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    436. Monoamine oxidase A gene (MAOA) associated with attitude towards longshot risks. (PubMed id 20046877)1 Zhong S....Chew S.H. (PLoS ONE 2009)
    437. Biosocial influences on fraudulent behaviors. (PubMed id 19492728)1 Beaver K.M. and Holtfreter K. (J Genet Psychol 2009)
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    441. Which genotype of MAO gene that the patients have are likely to be most susceptible to the symptoms of fibromyalgia? (PubMed id 17885758)1 GA1rsoy S....Sahin G. (Rheumatol. Int. 2008)
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    448. The monoamine oxidase inhibitor phenelzine enhances the discriminative stimulus effect of nicotine in rats. (PubMed id 17912044)7 Wooters T.E. and Bardo M.T. (Behav Pharmacol 2007)
    449. Pharmacokinetics and absolute bioavailability of selegiline following treatment of healthy subjects with the selegiline transdermal system (6 mg/24 h): a comparison with oral selegiline capsules. (PubMed id 17715422)7 Azzaro A.J....VanDenBerg C. (J Clin Pharmacol 2007)
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    768. Metabolism of nomifensine to a dihydroisoquinolinium ion metabolite by human myeloperoxidase, hemoglobin, monoamine oxidase A, and cytochrome P450 enzymes. (PubMed id 16679384)9 Obach R.S. and Dalvie D.K. (Drug Metab. Dispos. 2006)
    769. Molecular mechanism of the relation of monoamine oxidase B and its inhibitors to Parkinson's disease: possible implications of glial cells. (PubMed id 17447416)9 Nagatsu T. and Sawada M. (J. Neural Transm. Suppl. 2006)
    770. Estrogen-related receptors-stimulated monoamine oxidase B promoter activity is down-regulated by estrogen receptors. (PubMed id 16484337)9 Zhang Z....Teng C.T. (Mol. Endocrinol. 2006)
    771. Monoamine oxidase: isoforms and inhibitors in Parkinson's disease and depressive illness. (PubMed id 16402116)9 Youdim M.B. and Bakhle Y.S. (Br. J. Pharmacol. 2006)
    772. Human monoamine oxidase enzyme inhibition by coffee and beta-carbolines norharman and harman isolated from coffee. (PubMed id 16139309)9 Herraiz T. and Chaparro C. (Life Sci. 2006)
    773. [Genetic background of ADHD: population studies, genes of the catecholamine system]. (PubMed id 16756025)9 SA8opiAcn A....Hauser J. (Psychiatr. Pol. 2006)
    774. Synthesis, biological evaluation and 3D-QSAR of 1,3,5-trisubstituted-4,5-dihydro-(1H)-pyrazole derivatives as potent and highly selective monoamine oxidase A inhibitors. (PubMed id 16719786)9 Chimenti F....Langer T. (Curr. Med. Chem. 2006)
    775. A molecular correlate to the Gleason grading system for prostate adenocarcinoma. (PubMed id 16829574)9 True L....Nelson P.S. (Proc. Natl. Acad. Sci. U.S.A. 2006)
    776. Functional role of the &quot;aromatic cage&quot; in human monoamine oxidase B: structures and catalytic properties of Tyr435 mutant proteins. (PubMed id 16605246)9 Li M....Edmondson D.E. (Biochemistry 2006)
    777. Involvement of type A monoamine oxidase in neurodegeneration: regulation of mitochondrial signaling leading to cell death or neuroprotection. (PubMed id 17447417)9 Naoi M....Yamaoka Y. (J. Neural Transm. Suppl. 2006)
    778. Design, synthesis, and biological evaluation of semicarbazide-sensitive amine oxidase (SSAO) inhibitors with anti-inflammatory activity. (PubMed id 16570912)9 Wang E.Y....Linnik M.D. (J. Med. Chem. 2006)
    779. Elevated monoamine oxidase a levels in the brain: an explanation for the monoamine imbalance of major depression. (PubMed id 17088501)9 Meyer J.H....Houle S. (Arch. Gen. Psychiatry 2006)
    780. Molecular genetics of bipolar disorder. (PubMed id 16436192)9 Hayden E.P. and Nurnberger J.I. (Genes Brain Behav. 2006)
    781. Genetic and environmental influences on the development of alcoholism: resilience vs. risk. (PubMed id 17347351)9 Enoch M.A. (Ann. N. Y. Acad. Sci. 2006)
    782. Moclobemide upregulated Bcl-2 expression and induced neural stem cell differentiation into serotoninergic neuron via extracellular-regulated kinase pathway. (PubMed id 16702990)9 Chiou S.H....Chang Y.L. (Br. J. Pharmacol. 2006)
    783. The imidazoline I2-site ligands BU 224 and 2-BFI inhibit MAO-A and MAO-B activities, hydrogen peroxide production, and lipolysis in rodent and human adipocytes. (PubMed id 17056035)9 Bour S....CarpAcnAc C. (Eur. J. Pharmacol. 2006)
    784. Pharmacotherapy of social anxiety disorder: what does the evidence tell us? (PubMed id 17092192)9 Davidson J.R. (J Clin Psychiatry 2006)
    785. Translational neuroimaging: positron emission tomography studies of monoamine oxidase. (PubMed id 16265597)9 Fowler J.S....Wang G.J. (Mol Imaging Biol 2005)
    786. Mechanistic pharmacokinetic and pharmacodynamic modeling of CHF3381 (2-[(2,3-dihydro-1H-inden-2-yl)amino]acetamide monohydrochloride), a novel N-methyl-D-aspartate antagonist and monoamine oxidase-A inhibitor in healthy subjects. (PubMed id 15671203)9 Csajka C....Verotta D. (J. Pharmacol. Exp. Ther. 2005)
    787. Orientation of oxazolidinones in the active site of monoamine oxidase. (PubMed id 15950194)9 Jones T.Z....Ramsay R.R. (Biochem. Pharmacol. 2005)
    788. Acute inhibition of cardiac monoamine oxidase A after tobacco smoke inhalation: validation study of [11C]befloxatone in rats followed by a positron emission tomography application in baboons. (PubMed id 15833896)9 Valette H....Syrota A. (J. Pharmacol. Exp. Ther. 2005)
    789. Effects of 3,4-methylenedioxymethamphetamine (MDMA, 'Ecstasy') and para-methoxyamphetamine on striatal 5-HT when co-administered with moclobemide. (PubMed id 15804499)9 Freezer A....Irvine R.J. (Brain Res. 2005)
    790. Mutation of surface cysteine 374 to alanine in monoamine oxidase A alters substrate turnover and inactivation by cyclopropylamines. (PubMed id 15848762)9 VintAcm A.P....Ramsay R.R. (amp 2005)
    791. Social anxiety disorder : current treatment recommendations. (PubMed id 15907150)9 Muller J.E....Stein D.J. (CNS Drugs 2005)
    792. Steady-state pharmacokinetics and pharmacodynamics of CHF3381, a novel antineuropathic pain agent, in healthy subjects. (PubMed id 15801935)9 Astruc B....Imbimbo B.P. (Br J Clin Pharmacol 2005)
    793. Interdependent serotonin transporter and receptor pathways regulate S100A4/Mts1, a gene associated with pulmonary vascular disease. (PubMed id 16002749)9 Lawrie A....Rabinovitch M. (Circ. Res. 2005)
    794. Serotonin and aggressive behavior in rodents and nonhuman primates: predispositions and plasticity. (PubMed id 16289029)9 Ferrari P.F....Miczek K.A. (Eur. J. Pharmacol. 2005)
    795. Fast and slow metabolizers of Hoasca. (PubMed id 16149329)9 Callaway J.C. (J Psychoactive Drugs 2005)
    796. Identification of 4-substituted 1,2,3-triazoles as novel oxazolidinone antibacterial agents with reduced activity against monoamine oxidase A. (PubMed id 15658863)9 Reck F....Gravestock M.B. (J. Med. Chem. 2005)
    797. Human monoamine oxidase is inhibited by tobacco smoke: beta-carboline alkaloids act as potent and reversible inhibitors. (PubMed id 15582589)9 Herraiz T. and Chaparro C. (Biochem. Biophys. Res. Commun. 2005)
    798. A genetic analysis of serotonergic biosynthetic and metabolic enzymes in migraine using a DNA pooling approach. (PubMed id 16200390)9 Johnson M.P. and Griffiths L.R. (J. Hum. Genet. 2005)
    799. Molecular characterization of monoamine oxidase in zebrafish (Danio rerio). (PubMed id 15621520)9 Setini A....Nicotra A. (amp 2005)
    800. Fluorinated phenylcyclopropylamines. Part 4: effects of aryl substituents and stereochemistry on the inhibition of monoamine oxidases by 1-aryl-2-fluoro-cyclopropylamines. (PubMed id 15755651)9 Ye S....Kirk K.L. (amp 2005)
    801. Synthesis of novel N-substituted imidazolecarboxylic acid hydrazides as monoamine oxidase inhibitors. (PubMed id 15784243)9 Hadizadeh F. and Ghodsi R. (Farmaco 2005)
    802. Association analysis of the monoamine oxidase A and B genes with attention deficit hyperactivity disorder (ADHD) in an Irish sample: preferential transmission of the MAO-A 941G allele to affected children. (PubMed id 15717295)9 Domschke K....Hawi Z. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2005)
    803. Demonstration of isoleucine 199 as a structural determinant for the selective inhibition of human monoamine oxidase B by specific reversible inhibitors. (PubMed id 15710600)9 Hubalek F....Edmondson D.E. (J. Biol. Chem. 2005)
    804. Genetic features of antidepressant induced mania and hypo-mania in bipolar disorder. (PubMed id 15248044)9 Serretti A....Catalano M. (Psychopharmacology (Berl.) 2004)
    805. Uptake and metabolism of serotonin by ependymal primary cultures. (PubMed id 15453270)9 Verleysdonk S....Wellard J. (Neurochem. Res. 2004)
    806. Calcitonin gene-related peptide facilitates serotonin release from guinea-pig colonic mucosa via myenteric neurons and tachykinin NK2/NK3 receptors. (PubMed id 14718265)9 Kojima S....Kamikawa Y. (Br. J. Pharmacol. 2004)
    807. Dopamine toxicity involves mitochondrial complex I inhibition: implications to dopamine-related neuropsychiatric disorders. (PubMed id 15130772)9 Ben-Shachar D....Ljubuncic P. (Biochem. Pharmacol. 2004)
    808. Gender in obsessive-compulsive disorder: clinical and genetic findings. (PubMed id 15013025)9 Lochner C....Stein D.J. (Eur Neuropsychopharmacol 2004)
    809. Clinical pharmacology of MAO inhibitors: safety and future. (PubMed id 14697896)9 Yamada M. and Yasuhara H. (Neurotoxicology 2004)
    810. Effect of oral linezolid on the pressor response to intravenous tyramine. (PubMed id 15521893)9 Cantarini M.V....Hughes A.M. (Br J Clin Pharmacol 2004)
    811. Therapeutic applications of selective and non-selective inhibitors of monoamine oxidase A and B that do not cause significant tyramine potentiation. (PubMed id 14697899)9 Youdim M.B. and Weinstock M. (Neurotoxicology 2004)
    812. Conserved elements of the cytochrome P-450 superfamily found in monoamine oxidase B. (PubMed id 14697882)9 Lewis D.A....Abell C.W. (Neurotoxicology 2004)
    813. HPLC-based bioactivity profiling of plant extracts: a kinetic assay for the identification of monoamine oxidase-A inhibitors using human recombinant monoamine oxidase-A. (PubMed id 15501256)9 Dittmann K....Hamburger M. (Phytochemistry 2004)
    814. Tribulin and endogenous MAO-inhibitory regulation in vivo. (PubMed id 14697893)9 Medvedev A.E. and Glover V. (Neurotoxicology 2004)
    815. Structure and mechanism of monoamine oxidase. (PubMed id 15279562)9 Edmondson D.E....HubA!lek F. (Curr. Med. Chem. 2004)
    816. [A search for psychobiological determinants of anxiety disorders]. (PubMed id 16529167)9 Hajduk A. (Ann Acad Med Stetin 2004)
    817. Corrigendum to &quot;gender in obsessive-compulsive disorder: clinical and genetic findings&quot; [Eur. Neuropsychopharmacol. 14 (2004) 105-113]. (PubMed id 15468463)9 Lochner C....Stein D.J. (Eur Neuropsychopharmacol 2004)
    818. Association of the functional V158M catechol-O-methyl-transferase polymorphism with panic disorder in women. (PubMed id 15009906)9 Domschke K....Deckert J. (Int. J. Neuropsychopharmacol. 2004)
    819. [Molecular pharmacogenetic studies of drug responses to obsessive-compulsive disorder and six functional genes]. (PubMed id 15476175)9 Zhang L....Collier D. (Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2004)
    820. Synthesis of 4-methyl-thio-phenyl-propylamine and the evaluation of its interaction with different amine oxidases. (PubMed id 14697793)9 Gallardo-Godoy A....Unzeta M. (amp 2004)
    821. Computer visualisation of the active site of monoamine oxidase-A by means of selective inhibitors. (PubMed id 15035815)9 Medvedev A.E....Veselovsky A.V. (Inflammopharmacology 2003)
    822. Simple, potent, and selective pyrrole inhibitors of monoamine oxidase types A and B. (PubMed id 12620068)9 Silvestri R....Turini P. (J. Med. Chem. 2003)
    823. Experimental gene interaction studies with SERT mutant mice as models for human polygenic and epistatic traits and disorders. (PubMed id 14653307)9 Murphy D.L....Lesch K.P. (Genes Brain Behav. 2003)
    824. Effects of human growth hormone (hrGH) treatment on amine metabolism in rats subjected to extensive small bowel resection. (PubMed id 12624735)9 Fogel W.A....Andrzejewski W. (Amino Acids 2003)
    825. Molecular genetics in the analysis of suicide. (PubMed id 12822741)9 Souery D....Mendlewicz J. (Ann. Med. 2003)
    826. Demonstration of high monoaminoxidase-A levels in neuroendocrine gastroenteropancreatic tumors in vitro and in vivo-tumor visualization using positron emission tomography with 11C-harmine. (PubMed id 12900293)9 Orlefors H....BergstrAPm M. (Nucl. Med. Biol. 2003)
    827. 1-methyl-2-undecyl-4(1H)-quinolone as an irreversible and selective inhibitor of type B monoamine oxidase. (PubMed id 12672993)9 Lee M.K....Ro J.S. (amp 2003)
    828. Activities of extract and constituents of Banisteriopsis caapi relevant to parkinsonism. (PubMed id 12895680)9 Schwarz M.J....Lees A.D. (Pharmacol. Biochem. Behav. 2003)
    829. Dosage-sensitive X-linked locus influences the development of amygdala and orbitofrontal cortex, and fear recognition in humans. (PubMed id 12958079)9 Good C.D....Skuse D.H. (Brain 2003)
    830. Moclobemide: therapeutic use and clinical studies. (PubMed id 12595913)9 Bonnet U. (CNS Drug Rev 2003)
    831. Interactions of D-amphetamine with the active site of monoamine oxidase-A. (PubMed id 15035814)9 Ramsay R.R. and Hunter D.J. (Inflammopharmacology 2003)
    832. Synthesis and in vivo imaging properties of [11C]befloxatone: a novel highly potent positron emission tomography ligand for mono-amine oxidase-A. (PubMed id 12729662)9 Dolle F....Bottlaender M. (amp 2003)
    833. Mapping the cerebral monoamine oxidase type A: positron emission tomography characterization of the reversible selective inhibitor [11C]befloxatone. (PubMed id 12606609)9 Bottlaender M....Valette H. (J. Pharmacol. Exp. Ther. 2003)
    834. Decreased methylation and transcription repressor Sp3 up-regulated human monoamine oxidase (MAO) B expression during Caco-2 differentiation. (PubMed id 12855685)9 Wong W.K....Shih J.C. (J. Biol. Chem. 2003)
    835. Pathogenesis of hepatic encephalopathy: update on molecular mechanisms. (PubMed id 15025246)9 Butterworth R.F. (Indian J Gastroenterol 2003)
    836. Expression profiling of osteosarcoma cells transfected with MDR1 and NEO genes: regulation of cell adhesion, apoptosis, and tumor suppression-related genes. (PubMed id 12695554)9 Sanchez-Carbayo M....Cordon-Cardo C. ( a journal of technical methods and pathology 2003)
    837. Clinical pharmacokinetics of linezolid, a novel oxazolidinone antibacterial. (PubMed id 14531724)9 Stalker D.J. and Jungbluth G.L. (Clin Pharmacokinet 2003)
    838. [Molecular genetics of mood disorders]. (PubMed id 12451683)9 Ikeda M....Ozaki N. (Nihon Shinkei Seishin Yakurigaku Zasshi 2002)
    839. Ovarian steroid regulation of monoamine oxidase-A and -B mRNAs in the macaque dorsal raphe and hypothalamic nuclei. (PubMed id 11889496)9 Gundlah C....Bethea C.L. (Psychopharmacology (Berl.) 2002)
    840. Assessing the molecular genetics of attention networks. (PubMed id 12366871)9 Fossella J....Posner M.I. (BMC Neurosci 2002)
    841. Treatment of comorbid opiate addiction and attention-deficit hyperactivity disorder (residual type) with moclobemide: a case report. (PubMed id 11999916)9 Vaiva G....Bailly D. (amp 2002)
    842. Monoamine oxidase: radiotracer development and human studies. (PubMed id 12183115)9 Fowler J.S....Ding Y.S. (Methods 2002)
    843. Monoamine oxidase inhibitors: a new generation. (PubMed id 12473970)9 Robinson D.S. (Psychopharmacol Bull 2002)
    844. Antisocial alcoholism and serotonin-related polymorphisms: association tests. (PubMed id 12218658)9 Hill E.M....Burmeister M. (Psychiatr. Genet. 2002)
    845. In vitro biotransformation of the selective serotonin reuptake inhibitor citalopram, its enantiomers and demethylated metabolites by monoamine oxidase in rat and human brain preparations. (PubMed id 11840311)9 Kosel M....Baumann P. (Mol. Psychiatry 2002)
    846. Pharmacotherapy of social anxiety disorder. (PubMed id 11801236)9 Blanco C....Liebowitz M.R. (Biol. Psychiatry 2002)
    847. Effect of TV3326, a novel monoamine-oxidase cholinesterase inhibitor, in rat models of anxiety and depression. (PubMed id 11889501)9 Weinstock M....Youdim M.B. (Psychopharmacology (Berl.) 2002)
    848. Novel dual inhibitors of AChE and MAO derived from hydroxy aminoindan and phenethylamine as potential treatment for Alzheimer's disease. (PubMed id 12431053)9 Sterling J....Weinstock M. (J. Med. Chem. 2002)
    849. The pharmacokinetics of sumatriptan when administered with clarithromycin in healthy volunteers. (PubMed id 12017403)9 Moore K.H....Sale M. (Clin Ther 2002)
    850. Moclobemide in the treatment of hot flashes in postmenopausal women. (PubMed id 12665046)9 Tarim E....Kuscu E. (Adv Ther 2002)
    851. Analysis of ten candidate genes in autism by association and linkage. (PubMed id 11857571)9 Philippe A....Leboyer M. (Am. J. Med. Genet. 2002)
    852. Monoamine oxidase A and B activities in embryonic chick hepatocytes: differential regulation by retinoic acid. (PubMed id 11979502)9 Nicotra A....Conti Devirgiliis L. (Cell Biochem. Funct. 2002)
    853. Serotonergic pathway genes and subtypes of alcoholism: association studies. (PubMed id 11525423)9 Parsian A. and Cloninger C.R. (Psychiatr. Genet. 2001)
    854. Molecular genetics of bipolar disorder. (PubMed id 11377748)9 Kato T. (Neurosci. Res. 2001)
    855. Efficacy and tolerability of moclobemide in bulimia nervosa: a placebo-controlled trial. (PubMed id 11195257)9 Carruba M.O....Nisoli E. (Int Clin Psychopharmacol 2001)
    856. Coumarins derivatives as dual inhibitors of acetylcholinesterase and monoamine oxidase. (PubMed id 11543689)9 BrA1hlmann C....Carotti A. (J. Med. Chem. 2001)
    857. Inhibition of MAO-A fails to alter cocaine-induced increases in extracellular dopamine and norepinephrine in rat nucleus accumbens. (PubMed id 11245920)9 Pepper J.P....Rothman R.B. (Brain Res. Mol. Brain Res. 2001)
    858. Effects of histamine H3-receptor ligands on brain monoamine oxidase in various mammalian species. (PubMed id 11430877)9 Sakurai E....Oreland L. (Brain Res. 2001)
    859. Examining for association between candidate gene polymorphisms in the dopamine pathway and attention-deficit hyperactivity disorder: a family-based study. (PubMed id 11449400)9 Payton A....Thapar A. (Am. J. Med. Genet. 2001)
    860. Combined treatment with corticosteroids and moclobemide favors normalization of hypothalamo-pituitary-adrenal axis dysregulation in relapsing-remitting multiple sclerosis: a randomized, double blind trial. (PubMed id 11297592)9 Then Bergh F....Trenkwalder C. (J. Clin. Endocrinol. Metab. 2001)
    861. Candidate gene studies of bipolar disorder. (PubMed id 11405546)9 Jones I. and Craddock N. (Ann. Med. 2001)
    862. Neurotransmitter dysfunction in hepatic encephalopathy: new approaches and new findings. (PubMed id 11726089)9 Butterworth R.F. (Metab Brain Dis 2001)
    863. Allelic variation of serotonin transporter expression is associated with depression in Parkinson's disease. (PubMed id 11326308)9 MAPssner R....Lesch K.P. (Mol. Psychiatry 2001)
    864. Cardiovascular sympathomimetic amine interactions in rats treated with monoamine oxidase inhibitors and the novel oxazolidinone antibiotic linezolid. (PubMed id 11336106)9 Humphrey S.J....Stryd R.P. (J. Cardiovasc. Pharmacol. 2001)
    865. Catecholamine monoamine oxidase a metabolite in adrenergic neurons is cytotoxic in vivo. (PubMed id 11164826)9 Burke W.J....Ruggiero D.A. (Brain Res. 2001)
    866. [A behavioral and neurochemical study on the mechanism of the anxiolytic effect of monoamine oxidase inhibitors]. (PubMed id 11481866)9 Maki Y. (Hokkaido Igaku Zasshi 2001)
    867. Spectrometric evidence for the flavin-1-phenylcyclopropylamine inactivator adduct with monoamine oxidase N. (PubMed id 11331009)9 Mitchell D.J....Silverman R.B. (Biochemistry 2001)
    868. Analysis of 4-methylthioamphetamine in clinical specimens. (PubMed id 11471875)9 Elliott S.P. (Ann. Clin. Biochem. 2001)
    869. Production and metabolism of serotonin (5-HT) by the human adrenal cortex: paracrine stimulation of aldosterone secretion by 5-HT. (PubMed id 11600577)9 Lefebvre H....Kuhn J.M. (J. Clin. Endocrinol. Metab. 2001)
    870. Association studies of bipolar disorder. (PubMed id 11843779)9 Craddock N....Greening J. (Bipolar Disord 2001)
    871. Effect of omeprazole on the pharmacokinetics of moclobemide according to the genetic polymorphism of CYP2C19. (PubMed id 11309556)9 Yu K.S....Shin S.G. (Clin. Pharmacol. Ther. 2001)
    872. Predictors of treatment response in patients with posttraumatic stress disorder. (PubMed id 11294480)9 Connor K.M....Davidson J.R. (amp 2001)
    873. Role of monoamine oxidase inhibition and monoamine depletion in fenfluramine-induced neurotoxicity and serotonin release. (PubMed id 11881977)9 Halladay A.K....Wagner G.C. (amp 2001)
    874. Non-MAO A binding of clorgyline in white matter in human brain. (PubMed id 11739617)9 Fowler J.S....Zhu W. (J. Neurochem. 2001)
    875. Clinically significant drug interactions with agents specific for migraine attacks. (PubMed id 11460889)9 Eadie M.J. (CNS Drugs 2001)
    876. Mild learning difficulties and offending behaviour--is there a link with monoamine oxidase A deficiency? (PubMed id 11702062)9 Stamps V.R....Gurling H.M. (Psychiatr. Genet. 2001)
    877. Characterization of a major form of human isatin reductase and the reduced metabolite. (PubMed id 11722560)9 Usami N....Hara A. (Eur. J. Biochem. 2001)
    878. The covalent FAD of monoamine oxidase: structural and functional role and mechanism of the flavinylation reaction. (PubMed id 11761328)9 Edmondson D.E. and Newton-Vinson P. (amp 2001)
    879. Molecular determinants of MAO selectivity in a series of indolylmethylamine derivatives: biological activities, 3D-QSAR/CoMFA analysis, and computational simulation of ligand recognition. (PubMed id 10794685)9 MorA^n J.A....Pardo L. (J. Med. Chem. 2000)
    880. A promoter polymorphism in the monoamine oxidase A gene and its relationships to monoamine metabolite concentrations in CSF of healthy volunteers. (PubMed id 10867119)9 JAPnsson E.G....Sedvall G.C. (J Psychiatr Res 2000)
    881. Inhibition of monoamine oxidases by functionalized coumarin derivatives: biological activities, QSARs, and 3D-QSARs. (PubMed id 11123983)9 Gnerre C....Testa B. (J. Med. Chem. 2000)
    882. Adrenergic and noradrenergic plasma levels in Lesch-Nyhan disease. (PubMed id 10693160)9 Ernst M....Cohen R.M. (Neuropsychopharmacology 2000)
    883. Use of PET in neuroendocrine tumors. In vivo applications and in vitro studies. (PubMed id 10932603)9 Eriksson B....LAYngstrAPm B. (Q J Nucl Med 2000)
    884. Comparison of moclobemide with selective serotonin reuptake inhibitors (SSRIs) on sexual function in depressed adults. The Australian and German Study Groups. (PubMed id 10974600)9 Philipp M....Kohnen R. (Eur Neuropsychopharmacol 2000)
    885. A randomized, double-blind placebo-controlled trial of moclobemide in patients with chronic fatigue syndrome. (PubMed id 11030484)9 Hickie I.B....Lloyd A.R. (J Clin Psychiatry 2000)
    886. The FAD binding sites of human liver monoamine oxidases A and B: investigation of the role of flavin ribityl side chain hydroxyl groups in the covalent flavinylation reaction and catalytic activities. (PubMed id 10606764)9 Miller J.R....Edmondson D.E. (Biochim. Biophys. Acta 2000)
    887. [The influence of genes on the development of personality]. (PubMed id 10853361)9 Samochowiec J....Horodnicki J. (Psychiatr. Pol. 2000)
    888. An association between a polymorphism of the tryptophan hydroxylase gene and aggression in schizophrenia and schizoaffective disorder. (PubMed id 11204346)9 Nolan K.A....Saito T. (Psychiatr. Genet. 2000)
    889. Transport and metabolism of serotonin in the human placenta from normal and severely pre-eclamptic pregnancies. (PubMed id 10729753)9 Carrasco G....GonzA!lez C. (Gynecol. Obstet. Invest. 2000)
    890. [Seasonal characteristics of the monoaminergic regulation of the behavior of hibernating animals]. (PubMed id 11081224)9 Semenova T.P....Kolaeva S.G. (Ross Fiziol Zh Im I M Sechenova 2000)
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    892. Variability and validity of polymorphism association studies in Parkinson's disease. (PubMed id 10953187)9 Tan E.K....Ashizawa T. (Neurology 2000)
    893. Genetic associations with clinical characteristics in bipolar affective disorder and recurrent unipolar depressive disorder. (PubMed id 10686549)9 Ho L.W....Rubinsztein D.C. (Am. J. Med. Genet. 2000)
    894. Complications of cirrhosis III. Hepatic encephalopathy. (PubMed id 10728803)9 Butterworth R.F. (J. Hepatol. 2000)
    895. Rasagiline, a monoamine oxidase-B inhibitor, protects NGF-differentiated PC12 cells against oxygen-glucose deprivation. (PubMed id 10518120)9 Abu-Raya S....Lazarovici P. (J. Neurosci. Res. 1999)
    896. Moclobemide treatment in multiple sclerosis patients with comorbid depression: an open-label safety trial. (PubMed id 10334000)9 Barak Y....Achiron A. (J Neuropsychiatry Clin Neurosci 1999)
    897. Monoamine oxidase: from genes to behavior. (PubMed id 10202537)9 Shih J.C....Ridd M.J. (Annu. Rev. Neurosci. 1999)
    898. Sixth World Congress of Psychiatric Genetics X Chromosome Workshop. (PubMed id 10374746)9 Paterson A.D. (Am. J. Med. Genet. 1999)
    899. Social anxiety disorder: designing a pharmacologic treatment strategy. (PubMed id 10335676)9 Pollack M.H. (J Clin Psychiatry 1999)
    900. Regulation of heme oxygenase-1 expression by dopamine in cultured C6 glioma and primary astrocytes. (PubMed id 10581397)9 Schmidt J....Morgan J.I. (Brain Res. Mol. Brain Res. 1999)
    901. Benzylamine analog binding studies as probes of the substrate sites of monoamine oxidases A and B. (PubMed id 10065374)9 Edmondson D.E. (Drug Metab. Rev. 1999)
    902. Structure-activity relationships in the oxidation of para-substituted benzylamine analogues by recombinant human liver monoamine oxidase A. (PubMed id 10521274)9 Miller J.R. and Edmondson D.E. (Biochemistry 1999)
    903. Species-dependent differences in monoamine oxidase A and B-catalyzed oxidation of various C4 substituted 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridinyl derivatives. (PubMed id 10525109)9 Inoue H....Castagnoli N. (J. Pharmacol. Exp. Ther. 1999)
    904. Social phobia: diagnosis, severity and implications for treatment. (PubMed id 10361959)9 Montgomery S.A. (Eur Arch Psychiatry Clin Neurosci 1999)
    905. Pharmacokinetics of Hoasca alkaloids in healthy humans. (PubMed id 10404423)9 Callaway J.C....Mash D.C. (J Ethnopharmacol 1999)
    906. Befloxatone (Synthelabo). (PubMed id 16160936)9 Emilien G. (IDrugs 1999)
    907. Switching to moclobemide to reverse fluoxetine-induced sexual dysfunction in patients with depression. (PubMed id 9987207)9 Ramasubbu R. (amp 1999)
    908. Moclobemide in patients with dementia and depression. (PubMed id 10410765)9 Amrein R....Cameron A.M. (Adv Neurol 1999)
    909. Inversion of selectivity of N-substituted propargylamine monoamine oxidase inhibitors following structural modifications to quaternary salts. (PubMed id 10641793)9 Yu P.H. and Davis B.A. (amp 1999)
    910. Dysthymia: clinical picture, extent of overlap with chronic fatigue syndrome, neuropharmacological considerations, and new therapeutic vistas. (PubMed id 10357046)9 Brunello N....Wessely S. (J Affect Disord 1999)
    911. Imaging the neurochemistry of nicotine actions: studies with positron emission tomography. (PubMed id 11768169)9 Volkow N.D....Gatley S.J. (amp 1999)
    912. Hepatic encephalopathy: An update of pathophysiologic mechanisms. (PubMed id 10564534)9 Hazell A.S. and Butterworth R.F. (Proc. Soc. Exp. Biol. Med. 1999)
    913. A reversible monoamine oxidase A inhibitor, befloxatone: structural approach of its mechanism of action. (PubMed id 10482460)9 Wouters J....Durant F. (amp 1999)
    914. Unified approach to the analysis of genetic variation in serotonergic pathways. (PubMed id 10581480)9 Marshall S.E.... Welsh K.I. (Am. J. Med. Genet. 1999)
    915. MAO-A and -B gene knock-out mice exhibit distinctly different behavior. (PubMed id 10591056)9 Shih J.C. and Chen K. (Neurobiology (Bp) 1999)
    916. Inhibition of monoamine oxidase by pirlindole analogues: 3D-QSAR analysis. (PubMed id 10591049)9 Medvedev A.E....Axenova L.N. (Neurobiology (Bp) 1999)
    917. In vivo and in vitro evidence for hydrogen peroxide (H2O2) accumulation in the epidermis of patients with vitiligo and its successful removal by a UVB-activated pseudocatalase. (PubMed id 10537016)9 Schallreuter K.U....Hibberts N.A. (J. Investig. Dermatol. Symp. Proc. 1999)
    918. Effects of aging and glucocorticoid treatment on monoamine oxidase subtypes in rat cerebral cortex: therapeutic implications. (PubMed id 9886786)9 Slotkin T.A....Ritchie J.C. (Brain Res. Bull. 1998)
    919. The monoamine oxidase-A gene and major psychosis in Japanese subjects. (PubMed id 9807650)9 Sasaki T....Nanko S. (Biol. Psychiatry 1998)
    920. Allelic association between dinucleotide repeats at the monoamine oxidase loci and schizophrenia. (PubMed id 19698656)9 Wei J. and Hammings G. (Eur. Psychiatry 1998)
    921. Serotonin syndrome: history and risk. (PubMed id 9794145)9 Gillman P.K. (amp 1998)
    922. Monoamine oxidase activities in human cystic and colonic arteries--influence of age. (PubMed id 9564621)9 Figueiredo I.V....Callingham B.A. (J. Neural Transm. Suppl. 1998)
    923. A higher frequency of a low activity-related allele of the MAO-A gene in females with obsessive-compulsive disorder. (PubMed id 9861646)9 Camarena B....Nicolini H. (Psychiatr. Genet. 1998)
    924. Experience with tranylcypromine in early Parkinson's disease. (PubMed id 9564607)9 Fahn S. and Chouinard S. (J. Neural Transm. Suppl. 1998)
    925. Comparison of the effects of moclobemide and selegiline on tyramine-evoked mydriasis in man. (PubMed id 9663810)9 Bitsios P....Bradshaw C.M. (Br J Clin Pharmacol 1998)
    926. Norepinephrine transmitter metabolite generates free radicals and activates mitochondrial permeability transition: a mechanism for DOPEGAL-induced apoptosis. (PubMed id 9518674)9 Burke W.J....Lin T.S. (Brain Res. 1998)
    927. Detection and analysis of four polymorphic markers at the human monoamine oxidase (MAO) gene in Japanese controls and patients with Parkinson's disease. (PubMed id 9642149)9 Nakatome M....Honda K. (Biochem. Biophys. Res. Commun. 1998)
    928. Placebo-controlled trial of moclobemide in social phobia. (PubMed id 9534836)9 Schneier F.R....Liebowitz M.R. (Br J Psychiatry 1998)
    929. Clinical pharmacology of befloxatone: a brief review. (PubMed id 10333984)9 Rosenzweig P....Legangneux E. (J Affect Disord 1998)
    930. Selective inhibitors of monoamine oxidase (MAO). 5. 1-Substituted phenoxathiin inhibitors containing no nitrogen that inhibit MAO A by binding it to a hydrophobic site. (PubMed id 9622553)9 Harfenist M....White H.L. (J. Med. Chem. 1998)
    931. Type B monoamine oxidase activity in human brain malignant tumors. (PubMed id 10072212)9 Marcozzi G....MondovA- B. (Cancer Biochem. Biophys. 1998)
    932. [Change of tryptophan hydroxylase and monoamine oxidase A activities in experimental depression induced by social confrontation]. (PubMed id 9891212)9 Avgustinovich D.F....Kudriavtseva N.N. (Dokl. Akad. Nauk. 1998)
    933. The influence of the antidepressant pirlindole and its dehydro-derivative on the activity of monoamine oxidase A and GABAA receptor binding. (PubMed id 9564636)9 Medvedev A.E....Squires R.F. (J. Neural Transm. Suppl. 1998)
    934. Evaluation of efficacies of different classes of antidepressants in the forced swimming test in mice at different ages. (PubMed id 9608606)9 Bourin M....Baker G.B. (amp 1998)
    935. Regional and molecular separation of the four bioactivities of 'tribulin'. (PubMed id 9488167)9 Hucklebridge F....Clow A. (Neurosci. Lett. 1998)
    936. Alterations of neurotransmitter-related gene expression in human and experimental portal-systemic encephalopathy. (PubMed id 10206825)9 Butterworth R.F. (Metab Brain Dis 1998)
    937. Inhibition of monoamine oxidase by pirlindole analogues: 3D-QSAR and CoMFA analysis. (PubMed id 9845968)9 Medvedev A.E....Ivanov A.S. (J Chem Inf Comput Sci 1998)
    938. Role of monoamine oxidase type A and B on the dopamine metabolism in discrete regions of the primate brain. (PubMed id 9704592)9 Lakshmana M.K....Raju T.R. (Neurochem. Res. 1998)
    939. An open trial of moclobemide in the treatment of post-traumatic stress disorder. (PubMed id 9347385)9 Neal L.A....Fox C. (Int Clin Psychopharmacol 1997)
    940. [Poisoning with a reversible and selective monoaminooxidase inhibitor]. (PubMed id 9273760)9 Pall M....Eriksen N.D. (Ugeskr. Laeg. 1997)
    941. Increased stress response and beta-phenylethylamine in MAOB-deficient mice. (PubMed id 9326944)9 Grimsby J....Shih J.C. (Nat. Genet. 1997)
    942. The olfactory bulbectomized rat as a model of depression: an update. (PubMed id 9352586)9 Kelly J.P....Leonard B.E. (amp 1997)
    943. Quantitation of low abundance mRNAs in glial cells using different polymerase chain reaction (PCR)-based methods. (PubMed id 9385056)9 Santagati S....Maggi A. (Brain Res. Brain Res. Protoc. 1997)
    944. Serotonin syndrome and drug combinations: focus on MAOI and RIMA. (PubMed id 9224903)9 Hilton S.E....MAPller H.J. (Eur Arch Psychiatry Clin Neurosci 1997)
    945. Brofaromine versus imipramine in in-patients with major depression--a controlled trial. (PubMed id 9241569)9 Volz H.P....MAPller H.J. (J Affect Disord 1997)
    946. Pressor response to tyramine after single 24-hour application of a selegiline transdermal system in healthy males. (PubMed id 9089426)9 Barrett J.S....DiSanto A.R. (J Clin Pharmacol 1997)
    947. Moclobemide and imipramine in chronic depression (dysthymia): an international double-blind, placebo-controlled trial. International Collaborative Study Group. (PubMed id 9347378)9 Versiani M....Stabl M. (Int Clin Psychopharmacol 1997)
    948. Moclobemide for anxiety disorders: a focus on moclobemide for panic disorder. (PubMed id 9466172)9 Tiller J.W....Behnke K. (Int Clin Psychopharmacol 1997)
    949. [Inhibitory monoamine oxidases of the new generation]. (PubMed id 9432289)9 Nowakowska E. and Chodera A. (Pol. Merkur. Lekarski 1997)
    950. [Preventive treatment of migraine and chronic tension headache with moclobemide]. (PubMed id 9324719)9 Meienberg O. and Amsler F. (Praxis (Bern 1994) 1997)
    951. Inhibition of monoamine oxidase A by beta-carboline derivatives. (PubMed id 8990278)9 Kim H....Ramsay R.R. (Arch. Biochem. Biophys. 1997)
    952. Clonality analysis in tumours of women by PCR amplification of X-linked genes. (PubMed id 9120730)9 Peng H....Pan L. (J. Pathol. 1997)
    953. A fatality due to moclobemide. (PubMed id 9304853)9 Camaris C. and Little D. (J. Forensic Sci. 1997)
    954. Synthesis, conformational analysis and antidepressant activity of moclobemide new analogues. (PubMed id 9112832)9 Ghanbarpour A....Rashidi-Ranjbar P. (Pharm Acta Helv 1997)
    955. Increased density of catalytic sites and expression of brain monoamine oxidase A in humans with hepatic encephalopathy. (PubMed id 9048767)9 Mousseau D.D....Butterworth R.F. (J. Neurochem. 1997)
    956. Antidepressant use in the elderly. Current status of nefazodone, venlafaxine and moclobemide. (PubMed id 9259175)9 Goldberg R.J. (amp 1997)
    957. Monoamine oxidase genes polymorphisms and mood disorder. (PubMed id 9342198)9 Muramatsu T....Asai M. (Am. J. Med. Genet. 1997)
    958. [Monoamine oxidase inhibitors and pressor response to dietary amines]. (PubMed id 9503566)9 Tipton K.F. (Vopr. Med. Khim. 1997)
    959. Altered catecholamine synthesis and degradation in the epidermis of patients with atopic eczema. (PubMed id 9452885)9 Schallreuter K.U....BA1ttner G. (Arch. Dermatol. Res. 1997)
    960. Treatment of depression in Parkinson's disease with moclobemide: A pilot open-label study. (PubMed id 18591080)9 GimAcnez-RoldA!n S....Mateo D. (amp 1997)
    961. Formation of formaldehyde from adrenaline in vivo; a potential risk factor for stress-related angiopathy. (PubMed id 9131641)9 Yu P.H....Zuo D.M. (Neurochem. Res. 1997)
    962. Effects of past history of major depression on smoking characteristics, monoamine oxidase-A and -B activities and withdrawal symptoms in dependent smokers. (PubMed id 9179504)9 Berlin I....Launay J.M. (Drug Alcohol Depend 1997)
    963. Evaluation of four candidate genes encoding proteins of the dopamine pathway in familial and sporadic Parkinson's disease: evidence for association of a DRD2 allele. (PubMed id 9191771)9 PlantAc-Bordeneuve V....Harding A.E. (Neurology 1997)
    964. Increased monoamine oxidase A activity in the epidermis of patients with vitiligo. (PubMed id 8750929)9 Schallreuter K.U....Ehrke C. (Arch. Dermatol. Res. 1996)
    965. Epidural anaesthesia, ephedrine and phenylephrine in a patient taking moclobemide, a new monoamine oxidase inhibitor. (PubMed id 9038453)9 Martyr J.W. and Orlikowski C.E. (Anaesthesia 1996)
    966. Pharmacodynamics and pharmacokinetics of two dose regimens of befloxatone, a new reversible and selective monoamine oxidase inhibitor, at steady state in healthy volunteers. (PubMed id 8690815)9 Patat A....Rosenzweig P. (J Clin Pharmacol 1996)
    967. [Tribulin--a novel endogenous monoaminoxidase inhibitor (dedicated to the memory of Merton Sandler)]. (PubMed id 9148606)9 Medvedev A.R. (Vopr. Med. Khim. 1996)
    968. Human anti-mitochondria autoantibodies appearing in iproniazid-induced immunoallergic hepatitis recognize human liver monoamine oxidase B. (PubMed id 8573115)9 Pons C....Mansuy D. (Biochem. Biophys. Res. Commun. 1996)
    969. Direct analysis of candidate genes in impulsive behaviours. (PubMed id 8862874)9 Goldman D....Ozaki N. (Ciba Found. Symp. 1996)
    970. Functional characterization of 5-HT1D autoreceptors on the modulation of 5-HT release in guinea-pig mesencephalic raphe, hippocampus and frontal cortex. (PubMed id 8762094)9 el Mansari M. and Blier P. (Br. J. Pharmacol. 1996)
    971. Monoamine oxidase inhibitors. An update on drug interactions. (PubMed id 8713690)9 Livingston M.G. and Livingston H.M. (Drug Saf 1996)
    972. A double-blind randomized placebo-controlled study of the efficacy and safety of pirlindole, a reversible monoamine oxidase A inhibitor, in the treatment of depression. (PubMed id 9020990)9 De Wilde J.E....GAcczy J. (Acta Psychiatr Scand 1996)
    973. Moclobemide versus fluoxetine for double depression: a randomized double-blind study. (PubMed id 9023788)9 Duarte A....Delini-Stula A. (J Psychiatr Res 1996)
    974. The pharmacotherapy of social phobia. (PubMed id 8923113)9 Pollack M.H. and Gould R.A. (Int Clin Psychopharmacol 1996)
    975. Drug treatment of depression in the 1990s. An overview of achievements and future possibilities. (PubMed id 9118813)9 MAPller H.J. and Volz H.P. (Drugs 1996)
    976. Influence of age, frailty and liver function on the pharmacokinetics of brofaromine. (PubMed id 8866634)9 Zeeh J....Platt D. (Eur. J. Clin. Pharmacol. 1996)
    977. No evidence of linkage between schizophrenia and D2 dopamine receptor gene locus in Italian pedigrees. (PubMed id 8710185)9 Grassi E....Sorbi S. (Neurosci. Lett. 1996)
    978. Tyramine pharmacodynamics during combined administration of lazabemide and moclobemide. (PubMed id 8861736)9 Dingemanse J....Korn A. (Int J Clin Pharmacol Ther 1996)
    979. The role of cytochrome P450 2D6 in the metabolism of moclobemide. (PubMed id 8880082)9 HAortter S....Hiemke C. (Eur Neuropsychopharmacol 1996)
    980. Genetic elevation of monoamine oxidase levels in dopaminergic PC12 cells results in increased free radical damage and sensitivity to MPTP. (PubMed id 8978500)9 Wei Q....Andersen J.K. (J. Neurosci. Res. 1996)
    981. Monoamine oxidase-dependent metabolism of dopamine in the striatum and substantia nigra of L-DOPA-treated monkeys. (PubMed id 8949927)9 Di Monte D.A....Langston J.W. (Brain Res. 1996)
    982. [Serotonin syndrome in acute poisoning with antidepressive agents]. (PubMed id 9033760)9 Robert P....Cathala B. (Ann Fr Anesth Reanim 1996)
    983. A study of monoamine oxidase activity in fetal membranes. (PubMed id 8677764)9 Sekizawa A....Oguchi K. (Acta Obstet Gynecol Scand 1996)
    984. Brofaromine--a review of its pharmacological properties and therapeutic use. (PubMed id 9026374)9 Volz H.P....MAPller H.J. (J Neural Transm 1996)
    985. Different modes of data processing and statistical testing applied to the same set of pharmaco-EEG recordings: effects on the evaluation of a selective and reversible MAO A inhibitor (brofaromine). (PubMed id 8776746)9 Reimann I.W....Herrmann W.M. (Neuropsychobiology 1996)
    986. Moclobemide in the treatment of social phobia. (PubMed id 8923114)9 Nutt D. and Montgomery S.A. (Int Clin Psychopharmacol 1996)
    987. Species differences in the interactions of the anticonvulsant milacemide and some analogues with monoamine oxidase-B. (PubMed id 7646533)9 O'Brien E.M....Tipton K.F. (Biochem. Pharmacol. 1995)
    988. Serotonin receptors. Genetic insights into serotonin function. (PubMed id 8542294)9 Heath M.J. and Hen R. (Curr. Biol. 1995)
    989. Effect of aging on lazabemide binding, monoamine oxidase activity and monoamine metabolites in human frontal cortex. (PubMed id 8695059)9 Galva M.D....Picotti G.B. (J. Neural Transm. Gen. Sect. 1995)
    990. A reversible monoamine oxidase A inhibitor (moclobemide) facilitates smoking cessation and abstinence in heavy, dependent smokers. (PubMed id 7586937)9 Berlin I....Puech A.J. (Clin. Pharmacol. Ther. 1995)
    991. Reversible and selective inhibitors of monoamine oxidase A in mental and other disorders. (PubMed id 7717094)9 Priest R.G....Steinert J. (Acta Psychiatr Scand Suppl 1995)
    992. A risk-benefit assessment of moclobemide in the treatment of depressive disorders. (PubMed id 7741983)9 Norman T.R. and Burrows G.D. (Drug Saf 1995)
    993. A controlled double-blind trial of moclobemide and imipramine in the treatment of depression. (PubMed id 7570133)9 Kok L.P. and Tsoi W.F. (Singapore Med J 1995)
    994. Dopaminergic and serotonergic neurotransmitters in bone marrow transplant patients. (PubMed id 7544403)9 Davis D.G. and Sparks D.L. (J. Neurol. Sci. 1995)
    995. Recent advances in geriatric psychopharmacology. (PubMed id 8535049)9 Naranjo C.A....Bremner K.E. (amp 1995)
    996. Moclobemide safety: monitoring a newly developed product in the 1990s. (PubMed id 7593735)9 Hilton S....Ruch R. (J Clin Psychopharmacol 1995)
    997. Social phobia: the clinical efficacy and tolerability of the monoamine oxidase -A and serotonin uptake inhibitor brofaromine. A double-blind placebo-controlled study. (PubMed id 8619339)9 FahlAcn T....Pauli U. (Acta Psychiatr Scand 1995)
    998. Inhibition of mitochondrial complexes I and IV by 6-hydroxydopamine. (PubMed id 7796873)9 Glinka Y.Y. and Youdim M.B. (Eur. J. Pharmacol. 1995)
    999. Moclobemide versus clomipramine in nonmelancholic, nonpsychotic major depression. A Study group. (PubMed id 8848950)9 Lecrubier Y....Stabl M. (Acta Psychiatr Scand 1995)
    1000. Redox properties of the flavin cofactor of monoamine oxidases A and B and their relationship to the kinetic mechanism. (PubMed id 8584669)9 Ramsay R.R....Singer T.P. (Prog. Brain Res. 1995)
    1001. Studies of reversible and selective inhibitors of monoamine oxidase A in dysthymia. (PubMed id 7717093)9 PActursson H. (Acta Psychiatr Scand Suppl 1995)
    1002. Relevance of reversible inhibitors of monoamine oxidase type A and of reuptake inhibition for noradrenaline turnover. (PubMed id 7717090)9 Hartmann D....Amrein R. (Acta Psychiatr Scand Suppl 1995)
    1003. Effect of initial treatment with antidepressants as a predictor of outcome after 8 weeks. (PubMed id 8570762)9 Volz H.P....MAPller H.J. (Psychiatry Res 1995)
    1004. Moclobemide in chronic neuropathic pain: preliminary case reports. (PubMed id 7549169)9 Menkes D.B....Jones D. (Clin J Pain 1995)
    1005. L-dopa cytotoxicity to PC12 cells in culture is via its autoxidation. (PubMed id 7830076)9 Basma A.N....Geller H.M. (J. Neurochem. 1995)
    1006. Platelet and brain GABA-transaminase and monoamine oxidase activities in patients with complex partial seizures. (PubMed id 7750512)9 Kumlien E....Oreland L. (Epilepsy Res. 1995)
    1007. Treatment of vitiligo with a topical application of pseudocatalase and calcium in combination with short-term UVB exposure: a case study on 33 patients. (PubMed id 7599386)9 Schallreuter K.U....Levenig C. (Dermatology (Basel) 1995)
    1008. Monoamine oxidase A and B activities in heavy smokers. (PubMed id 8580230)9 Berlin I....Puech A.J. (Biol. Psychiatry 1995)
    1009. Clinical efficacy of reversible and selective inhibitors of monoamine oxidase A in major depression. (PubMed id 7717091)9 Paykel E.S. (Acta Psychiatr Scand Suppl 1995)
    1010. Norrie disease and MAO genes: nearest neighbors. (PubMed id 8541872)9 Chen Z.Y....Breakefield X.O. (Hum. Mol. Genet. 1995)
    1011. [The effect of pyrazidole on monoamine level in hypobaric hypoxia]. (PubMed id 8122400)9 Goroshinskaia I.A....Sorokina I.V. (Vopr. Med. Khim. 1994)
    1012. Characterization of the enzyme responsible for the metabolism of sumatriptan in human liver. (PubMed id 8161354)9 Dixon C.M....Tarbit M.H. (Biochem. Pharmacol. 1994)
    1013. Multicenter double-blind study of moclobemide and maprotiline. (PubMed id 7954483)9 Vaz-Serra A....Pestana L.C. (Clin Neuropharmacol 1994)
    1014. A cross-study comparison of the effects of moclobemide and brofaromine on actual driving performance and estimated sleep. (PubMed id 7954488)9 Ramaekers J.G....O'Hanlon J.F. (Clin Neuropharmacol 1994)
    1015. In vivo effects of the monoamine oxidase inhibitors Ro 41-1049 and Ro 19-6327 on the production and fate of renal dopamine. (PubMed id 7931252)9 Vieira-Coelho M.A....Soares-da-Silva P. (J. Neural Transm. Suppl. 1994)
    1016. Selective MAO-A and B inhibitors, radical scavengers and nitric oxide synthase inhibitors in Parkinson's disease. (PubMed id 7527888)9 Youdim M.B. and Lavie L. (Life Sci. 1994)
    1017. Brofaromine in non-endogenous major depressed inpatients--results of a preliminary dose-finding trial versus tranylcypromine. (PubMed id 7972347)9 Volz H.P....MAPller H.J. (Pharmacopsychiatry 1994)
    1018. Correlations of plasma and urinary phenylacetic acid and phenylethylamine concentrations with eating behavior and mood rating scores in brofaromine-treated women with bulimia nervosa. (PubMed id 7918350)9 Davis B.A....Boulton A.A. (amp 1994)
    1019. Experimental and theoretical study of reversible monoamine oxidase inhibitors: structural approach of the active site of the enzyme. (PubMed id 7931244)9 Wouters J....Jarreau F.X. (J. Neural Transm. Suppl. 1994)
    1020. Modulation of 5-HT release in the guinea-pig brain following long-term administration of antidepressant drugs. (PubMed id 7834200)9 Blier P. and Bouchard C. (Br. J. Pharmacol. 1994)
    1021. Biogenic amine metabolite patterns in the urine of monoamine oxidase A-deficient patients. A possible tool for diagnosis. (PubMed id 7807947)9 Abeling N.G....Brunner H.G. (J. Inherit. Metab. Dis. 1994)
    1022. Moclobemide for depression. (PubMed id 7635005)9 (Drug Ther Bull 1994)
    1023. Effects of monoamine oxidase A inhibition on plasma biogenic amine metabolites in depressed patients. (PubMed id 7527564)9 Markianos M....Stefanis C. (Psychiatry Res 1994)
    1024. Interaction of tetrahydrostilbazoles with monoamine oxidase A and B. (PubMed id 8289189)9 Sablin S.O....Tkachenko S.E. (J. Med. Chem. 1994)
    1025. Monoamine oxidase inhibitors, cognitive functions and neurodegenerative diseases. (PubMed id 7931235)9 Delumeau J.C....Allain H. (J. Neural Transm. Suppl. 1994)
    1026. Novel 4-(aryloxy)tetrahydropyridine analogs of MPTP as monoamine oxidase A and B substrates. (PubMed id 8151621)9 Kalgutkar A.S....Castagnoli N. (J. Med. Chem. 1994)
    1027. Inhibition of monoamine oxidase by clorgyline analogues. (PubMed id 7931241)9 O'Brien E.M....Dostert P. (J. Neural Transm. Suppl. 1994)
    1028. Comparison of the efficacy and tolerability of moclobemide and maprotiline in depressed patients treated by general practitioners. (PubMed id 7954482)9 Gachoud J.P....KAPhler M. (Clin Neuropharmacol 1994)
    1029. Identification of human monoamine oxidase (MAO) A and B gene promoters. (PubMed id 7931237)9 Shih J.C....Chen K. (J. Neural Transm. Suppl. 1994)
    1030. Moclobemide (Aurorix) in primary major depression. (PubMed id 8208985)9 Rihmer Z....GA!bor A. (amp 1994)
    1031. (-)-Deprenyl reduces PC12 cell apoptosis by inducing new protein synthesis. (PubMed id 7931312)9 Tatton W.G....Kwan M. (J. Neurochem. 1994)
    1032. Modulation of capsaicin induced airway reflexes in humans: effect of monoamine oxidase inhibition. (PubMed id 8443037)9 Choudry N.B....Fuller R.W. (Br J Clin Pharmacol 1993)
    1033. Is there a role for selective monoamine oxidase inhibitor therapy in bulimia nervosa? A placebo-controlled trial of brofaromine. (PubMed id 8120155)9 Kennedy S.H....Lofchy J. (J Clin Psychopharmacol 1993)
    1034. [An increase in the radioprotective effect of O-methyltyramine and mezaton by monoamine oxidase inhibitors]. (PubMed id 8469735)9 KulinskiA- V.I....Rumiantseva N.P. (Radiobiologiia 1993)
    1035. Integrative transporter-mediated release from cytoplasmic and vesicular 5-hydroxytryptamine stores in cultured neurons. (PubMed id 8100196)9 Gu X.F. and Azmitia E.C. (Eur. J. Pharmacol. 1993)
    1036. Double-blind comparison of moclobemide and tranylcypromine in depression. (PubMed id 8127928)9 Heinze G....Allen S.R. (Pharmacopsychiatry 1993)
    1037. Drug interactions with reversible monoamine oxidase-A inhibitors. (PubMed id 8313396)9 Callingham B.A. (Clin Neuropharmacol 1993)
    1038. Reversible monoamine oxidase-A inhibitors in resistant major depression. (PubMed id 8313400)9 Nolen W.A....Haffmans P.M. (Clin Neuropharmacol 1993)
    1039. Increased activities of MAOA and MAOB in autopsied brain tissue from cirrhotic patients with hepatic encephalopathy. (PubMed id 8242348)9 Rao V.L....Butterworth R.F. (Brain Res. 1993)
    1040. The effect of side chain substitution at positions 2 and 3 of the heterocyclic ring of N-acetylenic analogues of tryptamine as monoamine oxidase inhibitors. (PubMed id 8517863)9 Avila M....Unzeta M. (Biochem. Pharmacol. 1993)
    1041. Substrate-specific enhancement of the oxidative half-reaction of monoamine oxidase. (PubMed id 8443155)9 Tan A.K. and Ramsay R.R. (Biochemistry 1993)
    1042. Serotonin uptake inhibition by the monoamine oxidase inhibitor brofaromine. (PubMed id 8471696)9 Waldmeier P.C....Howald H. (Biol. Psychiatry 1993)
    1043. Reversible monoamine oxidase-A inhibitors in panic disorder. (PubMed id 8313401)9 Bakish D....D'Souza J. (Clin Neuropharmacol 1993)
    1044. In vitro hepatic biotransformation of moclobemide (Ro 11-1163) in man and rat. (PubMed id 8259692)9 VallA"s B....Rahmani R. ( the fate of foreign compounds in biological systems 1993)
    1045. Differential increases in catecholamine metabolizing enzymes in amyotrophic lateral sclerosis. (PubMed id 8405291)9 Ekblom J....Jossan S.S. (Exp. Neurol. 1993)
    1046. Brofaromine in depression: a Canadian multicenter placebo trial and a review of standard drug comparative studies. (PubMed id 8313397)9 Chouinard G....Kukha-Mohamad S.A. (Clin Neuropharmacol 1993)
    1047. An update of recent moclobemide interaction data. (PubMed id 8468439)9 Dingemanse J. (Int Clin Psychopharmacol 1993)
    1048. Synthesis and characterization of 11C-labeled fluoroclorgyline: a monoamine oxidase A specific inhibitor for positron emission tomography. (PubMed id 8293522)9 Ohmomo Y....Yokoyama A. (amp 1993)
    1049. Estrogen modulation of catecholamine synthesis and monoamine oxidase A activity in the human neuroblastoma cell line SK-ER3. (PubMed id 7903862)9 Ma Z.Q....Maggi A. (J. Steroid Biochem. Mol. Biol. 1993)
    1050. [Brain monoamine oxidase in aging wild Norway rats, chosen for lack of aggressive behavior toward humans]. (PubMed id 8511882)9 VoA-tenko N.N. (Vopr. Med. Khim. 1993)
    1051. Cytotoxicity of dopamine-derived 6,7-dihydroxy-1,2,3,4-tetrahydroisoquinolines. (PubMed id 8093579)9 Maruyama W....Naoi M. (Adv Neurol 1993)
    1052. Dopamine metabolism and neurotransmission in primate brain in relationship to monoamine oxidase A and B inhibition. (PubMed id 8390270)9 Youdim M.B. and Riederer P. (J. Neural Transm. Gen. Sect. 1993)
    1053. Clinical overview on moclobemide. (PubMed id 8255982)9 Tiller J.W. (amp 1993)
    1054. Newer aspects of the reversible inhibitor of MAO-A and serotonin reuptake, brofaromine. (PubMed id 8430214)9 Waldmeier P.C. (amp 1993)
    1055. Safety of moclobemide in clinical use. (PubMed id 8313399)9 Chen D.T. and Ruch R. (Clin Neuropharmacol 1993)
    1056. Reversible monoamine oxidase-A inhibitors in resistant major depression. (PubMed id 1498903)9 Nolen W.A....Haffmans P.M. (Clin Neuropharmacol 1992)
    1057. The new generation of monoamine oxidase inhibitors. (PubMed id 1609114)9 Cesura A.M. and Pletscher A. (Prog Drug Res 1992)
    1058. Biochemistry and pharmacology of moclobemide, a prototype RIMA. (PubMed id 1546143)9 Haefely W....Da Prada M. (Psychopharmacology (Berl.) 1992)
    1059. Brofaromine in panic disorder: a pilot study with a new reversible inhibitor of monoamine oxidase-A. (PubMed id 1494591)9 Garcia-Borreguero D....Krieg J.C. (Pharmacopsychiatry 1992)
    1060. RIMA: a safe concept in the treatment of depression with moclobemide. (PubMed id 1394030)9 Amrein R....Schmid-Burgk W. (Can J Psychiatry 1992)
    1061. Biochemical effects of high single doses of moclobemide in man: correlation with plasma concentrations. (PubMed id 1347659)9 Dingemanse J....GA1ntert T.W. (Psychopharmacology (Berl.) 1992)
    1062. Safety of moclobemide taken in overdose for attempted suicide. (PubMed id 1546127)9 Hetzel W. (Psychopharmacology (Berl.) 1992)
    1063. Deprenyl alters behavior and caudate dopamine through an amphetamine-like action. (PubMed id 1475291)9 Okuda C....Kuczenski R. (Pharmacol. Biochem. Behav. 1992)
    1064. Efficacy of moclobemide in different patient groups: a meta-analysis of studies. (PubMed id 1347658)9 Angst J. and Stabl M. (Psychopharmacology (Berl.) 1992)
    1065. New pharmacological approaches to the management of depression: from theory to clinical practice. (PubMed id 1580888)9 Norman T.R....Burrows G.D. (Aust N Z J Psychiatry 1992)
    1066. An Australian multicentre study of moclobemide versus amitriptyline in the treatment of depression. (PubMed id 1417632)9 Evans L....Adena M. (Aust N Z J Psychiatry 1992)
    1067. Brain gamma-aminobutyrate aminotransferase (GABA-T) and monoamine oxidase (MAO) in patients with Alzheimer's disease. (PubMed id 1627256)9 Sherif F....Oreland L. (J Neural Transm Park Dis Dement Sect 1992)
    1068. Antidepressants and cognition: comparative effects of moclobemide, viloxazine and maprotiline. (PubMed id 1546142)9 Allain H....Gandon J.M. (Psychopharmacology (Berl.) 1992)
    1069. Monoamine oxidase inhibitors phenelzine and brofaromine increase plasma serotonin and decrease 5-hydroxyindoleacetic acid in patients with major depression: relationship to clinical improvement. (PubMed id 1282522)9 Celada P....Artigas F. (J Clin Psychopharmacol 1992)

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    Entrez Gene: 4128 HGNC: 6833 AceView: MAOA Ensembl:ENSG00000189221 euGenes: HUgn4128
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