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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MAOA Gene

protein-coding   GIFtS: 72
GCID: GC0XP043515

Monoamine Oxidase A

Microbiology & Infectious Diseases Congress
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Monoamine Oxidase A1 2
Monoamine Oxidase Type A2 3
MAO-A2 3
EC 1.4.3.43 8
Amine Oxidase [Flavin-Containing] A2
EC 1.4.38

External Ids:    HGNC: 68331   Entrez Gene: 41282   Ensembl: ENSG000001892217   OMIM: 3098505   UniProtKB: P213973   

Export aliases for MAOA gene to outside databases

Previous GC identifers: GC0XP041545 GC0XP041794 GC0XP042360 GC0XP042636 GC0XP043271 GC0XP043400 GC0XP041246


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MAOA Gene:
This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the
oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results
in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including
antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
(provided by RefSeq, Jul 2012)

GeneCards Summary for MAOA Gene: 
MAOA (monoamine oxidase A) is a protein-coding gene. Diseases associated with MAOA include social phobia, and antisocial personality disorder, and among its related super-pathways are Polyamines are oxidized to amines, aldehydes and H2O2 by PAOs and Metabolic pathways. GO annotations related to this gene include primary amine oxidase activity. An important paralog of this gene is MAOB.

UniProtKB/Swiss-Prot: AOFA_HUMAN, P21397
Function: Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the
metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA
preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine

summary for MAOA Gene:
Monoamine Oxidases (MAO) catalyze the oxidation of monoamines such as dopamine, serotonin and adrenalin.
They are found bound to the outer membrane of mitochondria in most cell types in the body. Two subtypes of
monoamine oxidase have been identified: MAO-A and MAO-B. Both are found in neurons and astroglia, with MAO-A
also found in the liver, gastrointestinal tract and placenta and MAO-B in blood platelets. Abnormal
regulation of MAOs in the body has been associated with depression, substance abuse, attention deficit
disorder, and irregular sexual maturation.

Gene Wiki entry for MAOA (Monoamine oxidase A) Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.2  NT_079573.4  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MAOA gene promoter:
         MEF-2A   c-Fos   AP-1   ATF-2   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMAOA promoter sequence
   Search SABiosciences Chromatin IP Primers for MAOA

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAOA


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp11.3   Ensembl cytogenetic band:  Xp11.3   HGNC cytogenetic band: Xp11.4-p11.3

MAOA Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MAOA gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP043515:  view genomic region     (about GC identifiers)

Start:
43,515,409 bp from pter      End:
43,606,068 bp from pter
Size:
90,660 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: AOFA_HUMAN, P21397 (See protein sequence)
Recommended Name: Amine oxidase [flavin-containing] A  
Size: 527 amino acids; 59682 Da
Cofactor: FAD
Subunit: Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a
covalently bound flavin. Enzymatically active as monomer
Subcellular location: Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side
Mass spectrometry: Mass=60512; Mass_error=6; Method=Electrospray; Range=1-527; Source=PubMed:11812236;
5 PDB 3D structures from and Proteopedia for MAOA:
1H8Q (3D)        2BXR (3D)        2BXS (3D)        2Z5X (3D)        2Z5Y (3D)    
Secondary accessions: B4DF46 Q16426
Alternative splicing: 2 isoforms:  P21397-1   P21397-2   

Explore the universe of human proteins at neXtProt for MAOA: NX_P21397

Explore proteomics data for MAOA at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P21397

  • 4/22 DME Specific Peptides for MAOA (P21397) (see all 22)
     RQPVGRI  DYNNLWR  ERNLPSV  FPPVWNP 

    MAOA Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MAOA Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_000231.1  NP_001257387.1  

    ENSEMBL proteins: 
     ENSP00000340684   ENSP00000440846  
    Reactome Protein details: P21397
    Human Recombinant Protein Products for MAOA: 
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    Novus Biologicals MAOA Protein
    Novus Biologicals MAOA Lysates
    Sino Biological Recombinant Protein for MAOA
    Sino Biological Cell Lysate for MAOA 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MAOA 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005741mitochondrial outer membrane TAS--
    GO:0016021integral to membrane IEA--

    MAOA for ontologies           About GeneDecksing



    MAOA Antibody Products: 
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    Cloud-Clone Corp. CLIAs for MAOA


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR001613 Flavin_amine_oxidase
     IPR002937 Amino_oxidase

    Graphical View of Domain Structure for InterPro Entry P21397

    ProtoNet protein and cluster: P21397

    1 Blocks protein domain: IPB001613 Flavin-containing amine oxidase signature

    UniProtKB/Swiss-Prot: AOFA_HUMAN, P21397
    Similarity: Belongs to the flavin monoamine oxidase family


    MAOA for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: AOFA_HUMAN, P21397
    Function: Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the
    metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA
    preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine
    Catalytic activity: RCH(2)NHR' + H(2)O + O(2) = RCHO + R'NH(2) + H(2)O(2)

         Genatlas biochemistry entry for MAOA:
    monoamine oxidase A,overexpressed in female panic disorders

         Enzyme Numbers (IUBMB): EC 1.4.3.41 2 EC 1.4.32

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008131primary amine oxidase activity TAS--
    GO:0016491oxidoreductase activity ----
    GO:0050660flavin adenine dinucleotide binding ----
         
    MAOA for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for MAOA:
     Decreased viability 

         4 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Maoa):
     behavior/neurological  cardiovascular system  homeostasis/metabolism  nervous system 

    MAOA for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Maoatm1Shih for MAOA

       inGenious Targeting Laboratory - Custom generated mouse model solutions for MAOA 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MAOA

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MAOA 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MAOA 

    miRNA
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    miRTarBase miRNAs that target MAOA:
    hsa-mir-22 (MIRT005902)

    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MAOA
    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate MAOA (see all 13):
    hsa-miR-3163 hsa-miR-495 hsa-miR-767-3p hsa-miR-7-2* hsa-miR-1324 hsa-miR-3065-5p hsa-miR-624* hsa-miR-29b-1*
    SwitchGear 3'UTR luciferase reporter plasmidMAOA 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
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    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector: MAOA (NM_000240)
    Sino Biological Human cDNA Clone for MAOA
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MAOA
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAOA
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAOA


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for MAOA About   (see all 25)                                                                                              See pathways by source

    SuperPathContained pathways About
    1melatonin degradation II
    Metabolism of serotonin0.50
    melatonin degradation II0.50
    Monoamines are oxidized to aldehydes by MAOA and MAOB, producing NH3 and H2O20.50
    Amine Oxidase reactions0.50
    Serotonin clearance from the synaptic cleft0.50
    dopamine degradation0.33
    2Metabolism
    Metabolism0.40
    Metabolic pathways0.40
    3phenylalanine utilization
    phenylalanine degradation IV (mammalian, via side chain)0.70
    putrescine degradation III0.33
    phenylalanine utilization0.70
    noradrenaline and adrenaline degradation0.31
    4Enzymatic degradation of dopamine by COMT
    Enzymatic degradation of dopamine by COMT0.67
    Enzymatic degradation of Dopamine by monoamine oxidase0.67
    Dopamine clearance from the synaptic cleft0.67
    Neurotransmitter Clearance In The Synaptic Cleft0.43
    5tryptophan utilization II
    tryptophan utilization II0.70
    serotonin degradation0.36
    tryptophan utilization I0.70

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 EMD Millipore Pathway for MAOA
        Tyrosine metabolism p.1 (dopamine)


    1 GeneGo (Thomson Reuters) Pathway for MAOA
        Tyrosine metabolism p.1 (dopamine)

    5/13 BioSystems Pathways for MAOA (see all 13)
        Biogenic Amine Synthesis
    SIDS Susceptibility Pathways
    Oxidative Stress
    dopamine degradation
    noradrenaline and adrenaline degradation


    5/15        Reactome Pathways for MAOA (see all 15)
        Enzymatic degradation of dopamine by COMT
    Metabolism of serotonin
    Serotonin clearance from the synaptic cleft
    Enzymatic degradation of Dopamine by monoamine oxidase
    Transmission across Chemical Synapses

    1 PharmGKB Pathway for MAOA
        Selective Serotonin Reuptake Inhibitor Pathway, Pharmacodynamics

    5/13         Kegg Pathways  (Kegg details for MAOA) (see all 13):
        Glycine, serine and threonine metabolism
    Arginine and proline metabolism
    Histidine metabolism
    Tyrosine metabolism
    Phenylalanine metabolism


    MAOA for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MAOA

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/79 Interacting proteins for MAOA (P213972, 3 ENSP000003406844) via UniProtKB, MINT, STRING, and/or I2D (see all 79)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    NDRG1Q925973, ENSP000003199774I2D: score=3 STRING: ENSP00000319977
    ATP6V1B2P212812, ENSP000002763904MINT-4054731 STRING: ENSP00000276390
    YWHABP319463I2D: score=1 
    A2MP010232MINT-4054731
    About this table

    Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006576cellular biogenic amine metabolic process TAS8211186
    GO:0006805xenobiotic metabolic process TAS--
    GO:0007268synaptic transmission TAS--
    GO:0007269neurotransmitter secretion TAS--
    GO:0007610behavior TAS8211186

    MAOA for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    MAOA for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Compounds for MAOA available from Tocris Bioscience    About this table
    CompoundAction CAS #
    Rasagiline mesylate Selective, irreversible MAO-B inhibitor [161735-79-1]
    (R)-(-)-Deprenyl hydrochlorideMAO-B inhibitor[14611-52-0]
    MoclobemideReversible MAO-A inhibitor[71320-77-9]
    Lazabemide hydrochlorideSelective MAO-B inhibitor[103878-83-7]
    Bifemelane hydrochlorideMAO-A and MAO-B inhibitor[90293-01-9]

    10/43 HMDB Compounds for MAOA (see all 43)    About this table
    CompoundSynonyms CAS #PubMed Ids
    1-Methylhistamine1-Methyl-1H-imidazole-4-ethanamine (see all 21)501-75-7--
    1-Phenylethylaminea-phenylethylamine (see all 17)98-84-0--
    3,4-Dihydroxymandelaldehyde3,4-Dihydroxyphenylglycolaldehyde (see all 4)13023-73-9--
    3,4-DihydroxyphenylacetaldehydeProtocatechuatealdehyde (see all 2)5707-55-1--
    3-Methoxy-4-hydroxyphenylglycolaldehydea,4-dihydroxy-3-methoxy-Benzeneacetaldehyde (see all 4)17592-23-3--
    3-Methoxytyramine3-Methoxy-4-hydroxyphenylethyl amine (see all 7)554-52-9--
    4,6-Dihydroxyquinoline4,6-Quinolinediol (see all 2)3517-61-1--
    5-Hydroxyindoleacetaldehyde(5-hydroxy-1H-indol-3-yl)acetaldehyde (see all 6)1892-21-3--
    5-Hydroxykynurenamine5-Hydroxykynuramine (see all 3)708-23-6--
    5-Methoxytryptamine2-(5-Methoxy-1H-indol-3-yl)ethanamine (see all 10)608-07-1--

    10/37 DrugBank Compounds for MAOA (see all 37)    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Tranylcypromine-- 155-09-9targetinhibitor12504917 8749840 15351283 15276688 10548268 14574774 11752352 20655983 16495723 10027835 15049511 10494892 9829163
    Phenelzine-- 51-71-8targetantagonist17768678 17912044 14574774 11752352 7092487 19201819 16370964 18700056 9829163
    enzymesubstrate17768678 17912044 14574774 11752352 7092487 19201819 16370964 18700056 9829163 17768678
    PargylineBenzyl-methyl-2-propinylamin (see all 12)555-57-7targetinhibitor19300583 17823646 9564606 477738 16641841 17715422
    Phentermine-- 122-09-8targetantagonist11911838 11673765 10799660 10231134
    enzymeinhibitor11911838 11673765 10799660 10231134 11911838 10799660
    Moclobemide4-Chlor-N-(2-morpholinoethyl)benzamid (see all 11)71320-77-9targetinhibitor1705137 8875133 11752352
    enzymeinhibitor1705137 8875133 11752352 11752352
    SelegilineL-Deprenalin (see all 4)14611-51-9targetinhibitor19300583 17823646 16641841 17715422
    Almotriptan-- 181183-52-8enzymesubstrate12353056 12642466 15762767
    DopamineDopamin (see all 6)51-61-6enzymesubstrate15817751 18652859 20869994
    Flavin-Adenine Dinucleotide-- 146-14-5target--17139284 17016423 10592235
    FurazolidoneNitrofurazolidone (see all 3)67-45-8enzymeinhibitor12623758 2032659 10543364

    10/133 Novoseek inferred chemical compound relationships for MAOA gene (see all 133)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    maoa 98.5 1084 17692293 (10), 19224413 (8), 11927135 (8), 15936529 (8) (see all 99)
    moclobemide 94.9 153 1546132 (5), 8612391 (3), 9663810 (3), 9174681 (3) (see all 99)
    clorgyline 91.8 98 1741773 (4), 9564606 (3), 1893487 (3), 8243537 (2) (see all 54)
    brofaromine 90.8 33 8430214 (4), 1967018 (2), 8313400 (2), 8313393 (2) (see all 22)
    befloxatone 90.4 36 8613928 (8), 12729662 (3), 7665725 (2), 9728902 (2) (see all 15)
    kynuramine 89.7 14 20504539 (1), 8990278 (1), 16139309 (1), 8443155 (1) (see all 12)
    toloxatone 88.5 10 1546145 (2), 1705137 (2), 1424410 (2), 8713690 (1) (see all 6)
    tyramine 85.5 68 17561096 (4), 8255365 (3), 8695909 (2), 7665725 (2) (see all 37)
    pirlindole 83.5 16 8953568 (3), 9564636 (2), 12781338 (2), 9272198 (2) (see all 7)
    1-phenylcyclopropylamine 81.4 3 15755651 (1), 15848762 (1)

    Search CenterWatch for drugs/clinical trials and news about MAOA / AOFA

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MAOA gene (2 alternative transcripts): 
    NM_000240.3  NM_001270458.1  

    Unigene Cluster for MAOA:

    Monoamine oxidase A
    Hs.183109  [show with all ESTs]
    Unigene Representative Sequence: NM_001270458
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000338702(uc004dfy.3 uc011mkw.2) ENST00000497485 ENST00000490604
    ENST00000542639
    Congresses - knowledge worth sharing:  
    European Congress of Clinical Microbiology and Infectious Diseases (ECCMID) 10 - 13 May 2014

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MAOA
    8/13 QIAGEN miScript miRNA Assays for microRNAs that regulate MAOA (see all 13):
    hsa-miR-3163 hsa-miR-495 hsa-miR-767-3p hsa-miR-7-2* hsa-miR-1324 hsa-miR-3065-5p hsa-miR-624* hsa-miR-29b-1*
    SwitchGear 3'UTR luciferase reporter plasmidMAOA 3' UTR sequence
    Inhib. RNA
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    Clone
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    OriGene clones in human, mouse for MAOA (see all 7)
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    GenScript: all cDNA clones in your preferred vector: MAOA (NM_000240)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MAOA
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAOA
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAOA

    Additional mRNA sequence: 

    AK123241.1 AK223499.1 AK291769.1 AK293926.1 BC008064.2 BC044787.1 BT006651.1 M68840.1 
    X17192.1 

    11 DOTS entries:

    DT.95120451  DT.87015236  DT.101981844  DT.100025285  DT.100825058  DT.121278195  DT.100708824  DT.121278204 
    DT.95120454  DT.100718004  DT.70102839 

    24/267 AceView cDNA sequences (see all 267):

    AA659255 BM923944 AI915791 BX952460 CB162010 AI674356 AI088940 AI335934 
    CA444528 AI890731 R10233 AI159812 H82430 BM669916 NM_000240 R97085 
    AI313440 AI624415 CD671543 AW630749 N29331 BQ720697 BQ027513 F02245 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MAOA expression in normal human tissues (normalized intensities)      MAOA embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCTGAAGTTT
    MAOA Expression
    About this image


    MAOA expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/46 selected tissues (see all 46) fully expand
     
     Brain (Nervous System)    fully expand to see all 9 entries
             Cerebral Cortex
             ganglion/cranial/vagus X   
     
     Lung (Respiratory System)    fully expand to see all 7 entries
             Stem Bronchi
             lung ; pneumocytes   
     
     Epithelium
             vagina ; squamous epithelial cells   
     
     Bone (Muscoskeletal System)    fully expand to see all 6 entries
             TGFbeta3+BMP7-induced chondrocytes
             sensory organ/ear/inner ear   
     
     Adipose (Muscoskeletal System)    fully expand to see all 6 entries
             HyStem+BMP4-induced E15 cells
             Human Preadipocyte-visceral (HPA-v)   

    See MAOA Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MAOA

    SOURCE GeneReport for Unigene cluster: Hs.183109

    UniProtKB/Swiss-Prot: AOFA_HUMAN, P21397
    Tissue specificity: Heart, liver, duodenum, blood vessels and kidney

        SABiosciences Expression via Pathway-Focused PCR Arrays including MAOA: 
              Amino Acid Metabolism II in human mouse rat
              Drug Metabolism: Phase I Enzymes in human mouse rat
              Molecular Toxicology PathwayFinder 384HT in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for MAOA
    OriGene qSTAR qPCR primer pairs in human, mouse for MAOA
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MAOA
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAOA
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAOA
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAOA

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for MAOA gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Maoa1 , 5 monoamine oxidase A1, 5 85.19(n)1
    88.12(a)1
      X (11.78 cM)5
    171611  NM_173740.31  NP_776101.31 
     166196985 
    chicken
    (Gallus gallus)
    Aves MAOA6
    monoamine oxidase A
    72(a)
    1 ↔ 1
    1(110613430-110658911)
    lizard
    (Anolis carolinensis)
    Reptilia MAOA6
    monoamine oxidase A
    72(a)
    1 ↔ 1
    3(135069134-135125415)
    zebrafish
    (Danio rerio)
    Actinopterygii mao6
    si:ch211-127i16.26
    si:ch211-127i16.2
    69(a)
    32(a)
    1 ↔ many
    possible ortholog
    9(34618751-34683759)
    10(19461623-19528134)


    ENSEMBL Gene Tree for MAOA (if available)
    TreeFam Gene Tree for MAOA (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MAOA gene
    MAOB2  
    1 SIMAP similar gene for MAOA using alignment to 7 protein entries:     AOFA_HUMAN (see all proteins):
    MAOB

    MAOA for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    UniProtKB/Swiss-Prot: AOFA_HUMAN, P21397
    Polymorphism: A polymorphism 1.2 kb upstream of the MAOA coding sequences consists of a 30-bp repeated sequence
    present in 3, 3.5, 4, or 5 copies. The polymorphism affect transcriptional activity of the MAOA gene promoter.
    Alleles with 3.5 or 4 copies of the repeat sequence are transcribed 2 to 10 times more efficiently than those
    with 3 or 5 copies of the repeat


    10/1109 SNPs in MAOA are shown (see all 1109)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0365454
    A breast cancer sample4--see VAR_0365452 D E mis40--------
    rs725546321,2
    Cpathogenic143591031(+) TAATTC/TAGCGG 4 Q * stg10--------
    rs1923952121,2
    --43512260(+) AGGATC/TGAGGC 2 -- us2k10--------
    rs66518041,2
    C,F--43512290(+) caGTCA/GGCCTC 2 -- us2k12Minor allele frequency- G:0.00WA CSA 3
    rs66518051,2
    C,F--43512293(+) TCGGCT/CTCAGC 2 -- us2k12Minor allele frequency- C:0.00WA CSA 3
    rs48246571,2
    C,F,A,H--43512302(+) GCAGCC/GTTGTC 2 -- us2k110Minor allele frequency- G:0.32NA WA CSA 19
    rs1904159451,2
    --43512369(+) TTTTTC/TCTACC 2 -- us2k10--------
    rs1118209341,2
    C,F--43512512(+) ACATTC/TGTCAG 2 -- us2k11Minor allele frequency- T:0.00CSA 1
    rs1816096531,2
    --43512744(+) GATTTC/TTTCAT 2 -- us2k10--------
    rs1843172791,2
    --43512882(+) CATATG/TTCTTT 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for MAOA (43515409 - 43606068 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for MAOA:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv21483CNV Gain19812545
    nsv517873CNV Gain19592680


    Human Gene Mutation Database (HGMD): MAOA

    Locus Specific Mutation Databases (LSDB): MAOA
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing MAOA
    DNA2.0 Custom Variant and Variant Library Synthesis for MAOA

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 309850   
    OMIM disorders: 300615  
    UniProtKB/Swiss-Prot: AOFA_HUMAN, P21397
  • Brunner syndrome (BRUNS) [MIM:300615]: A form of X-linked non-dysmorphic mild mental retardation. Male
    patients are affected by borderline mental retardation and exhibit abnormal behavior, including disturbed
    regulation of impulsive aggression. Obligate female carriers have normal intelligence and behavior. Note=The
    disease is caused by mutations affecting the gene represented in this entry

  • 20/107 diseases for MAOA (see all 107):    About MalaCards
    social phobia    antisocial personality disorder    postpartum depression    substance abuse
    avoidant personality disorder    maoa-related behavior disorders    brunner syndrome    personality disorder
    conduct disorder    paranoid schizophrenia    serotonin syndrome    borderline personality disorder
    melancholia    hepatic encephalopathy    novelty seeking personality    post-traumatic stress disorder
    exhibitionism    severe pre-eclampsia    specific phobia    anxiety disorder

    13 diseases from the University of Copenhagen DISEASES database for MAOA:
    Parkinson's disease     Anxiety disorder     Antisocial personality disorder     Conduct disorder
    Attention deficit hyperactivity disorder     Endogenous depression     Schizophrenia     Toxic encephalopathy
    Melancholia     Alcohol dependence     Avoidant personality disorder     Borderline personality disorder
    Migraine

    MAOA for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    10/76 Novoseek inferred disease relationships for MAOA gene (see all 76)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    antisocial behavior 75.8 57 17008143 (4), 18023041 (3), 19120058 (3), 10359483 (2) (see all 20)
    borderline mental retardation 74.5 3 8776592 (1), 9326944 (1), 8613523 (1)
    antisocial personality disorder 65.4 32 12824808 (5), 17007976 (3), 10049583 (2), 20175604 (2) (see all 10)
    major depression 64.7 65 18337637 (4), 10564737 (4), 17884271 (4), 9179504 (3) (see all 28)
    aggressive behavior 63 36 15817751 (3), 15211623 (2), 18996506 (2), 17657171 (2) (see all 22)
    crisis hypertensive 59.4 7 17554106 (1), 9829163 (1), 14697896 (1), 19527191 (1)
    attention-deficit hyperactivity disorder 55.8 15 17230031 (2), 8862874 (1), 12140786 (1), 19309535 (1) (see all 13)
    bipolar disorder 53.7 47 10402508 (4), 8776592 (3), 9342194 (3), 16958037 (3) (see all 21)
    phobia social 53.6 8 8313403 (2), 10361959 (1), 8619339 (1), 9534836 (1) (see all 5)
    parkinson disease 52.5 32 7593732 (3), 17044053 (2), 8358501 (2), 9579294 (2) (see all 22)

    Genetic Association Database (GAD): MAOA
    Human Genome Epidemiology (HuGE) Navigator: MAOA (290 documents)

    Export disorders for MAOA gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MAOA gene, integrated from 9 sources (see all 1095) (see top 10):
    (articles sorted by number of sources associating them with MAOA)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A non-additive interaction of a functional MAO-A VNTR and testosterone predicts antisocial behavior. (PubMed id 17429405)1, 4, 7, 9 Sjoberg R.L....Goldman D. (2008)
    2. Early trauma and increased risk for physical aggression during adulthood: the moderating role of MAOA genotype. (PubMed id 17534436)1, 4, 9 Frazzetto G....Troisi A. (2007)
    3. A promoter polymorphism in the monoamine oxidase A gene is associated with the pineal MAOA activity in Alzheimer's disease patients. (PubMed id 17692293)1, 4, 9 Wu Y.H....Swaab D.F. (2007)
    4. [Association study of the polymorphisms of monoamine oxidase A genes with schizophrenia] (PubMed id 17680543)1, 4, 9 Shi Y.Z....Lou B.Y. (2007)
    5. Three-dimensional structure of human monoamine oxidase A (MAO A): relation to the structures of rat MAO A and human MAO B. (PubMed id 16129825)1, 2, 9 De Colibus L.... Mattevi A. (2005)
    6. Analysis of monoamine oxidase A (MAOA) promoter polymorphism in Finnish male alcoholics. (PubMed id 11927135)1, 4, 9 Saito T....Tiihonen J. (2002)
    7. Structure of human monoamine oxidase A at 2.2-A resolution: the control of opening the entry for substrates/inhibitors. (PubMed id 18391214)1, 2, 9 Son S.-Y.... Tsukihara T. (2008)
    8. Effects of MAOA-genotype, alcohol consumption, and aging on violent behavior. (PubMed id 19120058)1, 4, 9 Tikkanen R....Virkkunen M. (2009)
    9. The development of peripartum depressive symptoms is associated with gene polymorphisms of MAOA, 5-HTT and COMT. (PubMed id 19625011)1, 4, 9 Doornbos B....Korf J. (2009)
    10. MAOA gene polymorphisms and response to mirtazapine in major depression. (PubMed id 19382113)1, 4, 9 Tzeng D.S....Yang C.Y. (2009)
    11. Monoamine oxidase A genotype predicts human serotonin 1A receptor availability in vivo. (PubMed id 18971477)1, 4, 9 Mickey B.J....Zubieta J.K. (2008)
    12. MAOA, maltreatment, and gene-environment interaction predicting children's mental health: new evidence and a meta-analysis. (PubMed id 16801953)1, 4, 9 Kim-Cohen J....Moffitt T.E. (2006)
    13. MAOA promoter polymorphism and attention deficit hyperactivity disorder (ADHD) in indian children. (PubMed id 16856146)1, 4, 9 Das M....Mukhopadhyay K. (2006)
    14. Cluster B personality disorders are associated with allelic variation of monoamine oxidase A activity. (PubMed id 15870836)1, 4, 9 Jacob C.P....Lesch K.P. (2005)
    15. Telomeric length varies with age and polymorphisms of the MAOA gene promoter in peripheral blood cells obtained from a community in Taiwan. (PubMed id 15722955)1, 4, 9 Lung F.W....Shu B.C. (2005)
    16. Gene-gene interaction between MAOA and COMT in suicidal behavior. (PubMed id 15936529)1, 4, 9 De Luca V....Kennedy J.L. (2005)
    17. Association of variations in monoamine oxidases A and B with Parkinson's disease subgroups. (PubMed id 14962671)1, 4, 9 Parsian A....Perlmutter J.S. (2004)
    18. Analysis of monoamine oxidase A (MAO-A) promoter polymorphism in male heroin-dependent subjects: behavioural and personality correlates. (PubMed id 15088154)1, 4, 9 Gerra G....Donnini C. (2004)
    19. A regulatory monoamine oxidase a promoter polymorphism and personality traits. (PubMed id 12566936)1, 4, 9 Garpenstrand H....Jonsson E.G. (2002)
    20. No association of the MAOA gene with alcoholism among Han Chinese males in Taiwan. (PubMed id 11999895)1, 4, 9 Lu R.B....Shih J.C. (2002)
    21. Promoter organization and activity of human monoamine oxidase (MAO) A and B genes. (PubMed id 1432104)1, 2, 9 Zhu Q.S.... Shih J.C. (1992)
    22. Structure of the human gene for monoamine oxidase type A. (PubMed id 1886775)1, 2, 9 Chen Z.-Y.... Hsu Y.-P.P. (1991)
    23. Monoamine oxidase A and childhood adversity as risk factors for conduct disorder in females. (PubMed id 18752729)1, 4, 9 Prom-Wormley E.C....Silberg J.L. (2008)
    24. Association analysis of monoamine oxidase A gene and bipolar affective disorder in Han Chinese. (PubMed id 18501009)1, 4, 9 Lin Y.M....Sun H.S. (2008)
    25. Possible interaction between MAOA and DRD2 genes associated with antisocial alcoholism among Han Chinese men in Taiwan. (PubMed id 17007976)1, 4, 9 Wang T.J....Lu R.B. (2007)
    26. The monoamine oxidase A (MAO-A) gene, family function and maltreatment as predictors of destructive behaviour during male adolescent alcohol consumption. (PubMed id 17298646)1, 4, 9 Nilsson K.W....Oreland L. (2007)
    27. MAOA and the 'cycle of violence:' childhood abuse and neglect, MAOA genotype, and risk for violent and antisocial behavior. (PubMed id 16814261)1, 4, 9 Widom C.S. and Brzustowicz L.M. (2006)
    28. A functional polymorphism in the MAOA gene promoter (MAOA-LPR) predicts central dopamine function and body mass index. (PubMed id 16770335)1, 4, 9 Ducci F....Goldman D. (2006)
    29. Monoamine oxidase A (MAOA) and antisocial behaviors in the presence of childhood and adolescent maltreatment. (PubMed id 15806601)1, 4, 9 Haberstick B.C....Hewitt J.K. (2005)
    30. Association analysis of monoamine oxidase A and attention deficit hyperactivity disorder. (PubMed id 12497620)1, 4, 9 Lawson D.C....Thapar A. (2003)
    31. Meta-analysis of the association between the monoamin e oxidase-A gene and mood disorders. (PubMed id 20010318)1, 4, 9 Fan M....Zhang J. (2010)
    32. Association of VNTR polymorphisms in the MAOA promote r and DRD4 exon 3 with heroin dependence in male Chinese addicts. (PubMed id 20218801)1, 4, 9 Chien C.C....Lung F.W. (2010)
    33. Monoamine oxidase A gene (MAOA) predicts behavioral aggression following provocation. (PubMed id 19168625)1, 4, 9 McDermott R....Johnson D.D. (2009)
    34. Association between monoamine oxidase (MAO)-A gene va riants and schizophrenia in a Chinese population. (PubMed id 19573521)1, 4, 9 Qiu H.T....Zhang X.Y. (2009)
    35. Neither single-marker nor haplotype analyses support an association between monoamine oxidase A gene and bipolar disorder. (PubMed id 18437281)1, 4, 9 Huang S.Y....Lu R.B. (2008)
    36. Differential association between MAOA, ADHD and neuropsychological functioning in boys and girls. (PubMed id 18726986)1, 4, 9 Rommelse N.N....Franke B. (2008)
    37. Interaction between a functional MAOA locus and childhood sexual abuse predicts alcoholism and antisocial personality disorder in adult women. (PubMed id 17592478)1, 4, 9 Ducci F....Goldman D. (2008)
    38. Sexually dimorphic effects of four genes (COMT, SLC6A2, MAOA, SLC6A4) in genetic associations of ADHD: a preliminary study. (PubMed id 18937309)1, 4, 9 Biederman J....Faraone S.V. (2008)
    39. Association of MAO-A variant with complicated grief in major depression. (PubMed id 18337637)1, 4, 9 Kersting A....Domschke K. (2007)
    40. Convergent genetic modulation of the endocrine stress response involves polymorphic variations of 5-HTT, COMT and MAOA. (PubMed id 17453062)1, 4, 9 Jabbi M....den Boer J.A. (2007)
    41. The MAOA promoter polymorphism, disruptive behavior disorders, and early onset substance use disorder: gene-environment interaction. (PubMed id 18075472)1, 4, 9 Vanyukov M.M....Ferrell R.E. (2007)
    42. Childhood maltreatment, subsequent antisocial behavior, and the role of monoamine oxidase A genotype. (PubMed id 17008143)1, 4, 9 Huizinga D....Hewitt J.K. (2006)
    43. No allele variation of the MAOA gene promoter in male Chinese subjects with attention deficit hyperactivity disorder. (PubMed id 17230031)1, 4, 9 Lung F.W....Kao W.T. (2006)
    44. [Association of functional genes polymorphisms of key enzymes in the metabolism of biogenic amines with paranoid schizophrenia susceptibility and the influence of these polymorphisms on PANSS results in antipsychotic treatment] (PubMed id 17217235)1, 4, 9 Tybura P....Samochowiec J. (2006)
    45. Monoamine oxidases A and B gene polymorphisms in migraine patients. (PubMed id 15694196)1, 4, 9 Filic V....Jernej B. (2005)
    46. No association between monoamine oxidase A promoter polymorphism and personality traits in Japanese females. (PubMed id 16139427)1, 4, 9 Hakamata Y....Inada T. (2005)
    47. Polymorphisms in the MAOA, MAOB, and COMT genes and aggressive behavior in schizophrenia. (PubMed id 15211623)1, 4, 9 Zammit S....Owen M.J. (2004)
    48. Neither antisocial personality disorder nor antisocial alcoholism is associated with the MAO-A gene in Han Chinese males. (PubMed id 12824808)1, 4, 9 Lu R.B....Shih J.C. (2003)
    49. Association analysis of MAOA and COMT with neuroticism assessed by peers. (PubMed id 12815746)1, 4, 9 Eley T.C....Craig I. (2003)
    50. Human monoamine oxidase A and B genes exhibit identical exon-intron organization. (PubMed id 2023912)1, 2, 9 Grimsby J.... Shih J.C. (1991)
    51. MAOA is associated with methylphenidate improvement of oppositional symptoms in boys with attention deficit hyperactivity disorder. (PubMed id 19309535)1, 4, 9 GuimarALes A.P....Hutz M.H. (2009)
    52. Negative emotionality: monoamine oxidase B gene varia nts modulate personality traits in healthy humans. (PubMed id 19657584)1, 4, 9 Dlugos A.M....de Wit H. (2009)
    53. Reduced amygdala-prefrontal coupling in major depression: association with MAOA genotype and illness severity. (PubMed id 18544183)1, 4, 9 Dannlowski U....Suslow T. (2008)
    54. Further evidence of MAO-A gene variants associated with bipolar disorder. (PubMed id 16958037)1, 4, 9 Muller D.J....Kennedy J.L. (2007)
    55. Monoamine oxidase-A polymorphisms might modify the association between the dopamine D2 receptor gene and alcohol dependence. (PubMed id 17476365)1, 4, 9 Huang S.Y....Lu R.B. (2007)
    56. Polymorphisms of dopamine degradation enzyme (COMT and MAO) genes and tardive dyskinesia in patients with schizophrenia. (PubMed id 15261699)1, 4, 9 Matsumoto C....Nakamura J. (2004)
    57. Association of a MAOA gene variant with generalized anxiety disorder, but not with panic disorder or major depression. (PubMed id 12555227)1, 4, 9 Tadic A....Dahmen N. (2003)
    58. Functional variation in promoter region of monoamine oxidase A and subtypes of alcoholism: haplotype analysis. (PubMed id 12555234)1, 4, 9 Parsian A....Zhang Z.H. (2003)
    59. No evidence of an association between a functional monoamine oxidase a gene polymorphism and completed suicides. (PubMed id 11920860)1, 4, 9 Ono H....Maeda K. (2002)
    60. MAO-A and COMT polymorphisms and gene effects in narcolepsy. (PubMed id 11443519)1, 4, 9 Dauvilliers Y....Tafti M. (2001)
    61. Psychopathy trait scores in adolescents with childhoo d ADHD: the contribution of genotypes affecting MAOA, 5HTT and COMT activity. (PubMed id 19829167)1, 4, 9 Fowler T....Thapar A. (2009)
    62. Serotonin genes and gene-gene interactions in borderline personality disorder in a matched case-control study. (PubMed id 19032968)1, 4, 9 Ni X....Kennedy J.L. (2008)
    63. Serotonin transporter (5-HTTLPR) and monoamine oxidase (MAOA) promoter polymorphisms in women with severe alcoholism. (PubMed id 18827956)1, 4, 9 Gokturk C....Hallman J. (2008)
    64. The MAO-A gene, platelet MAO-B activity and psychosocial environment in adolescent female alcohol-related problem behaviour. (PubMed id 18029114)1, 4, 9 Nilsson K.W....Oreland L. (2008)
    65. A community-based study of cigarette smoking behavior in relation to variation in three genes involved in dopamine metabolism: Catechol-O-methyltransferase (COMT), dopamine beta-hydroxylase (DBH) and monoamine oxidase-A (MAO-A). (PubMed id 18486967)1, 4, 9 Shiels M.S....Alberg A.J. (2008)
    66. Meta-study on association between the monoamine oxidase A gene (MAOA) and schizophrenia. (PubMed id 17894408)1, 4, 9 Li D. and He L. (2008)
    67. Gene-gene interaction analysis of personality traits in a Japanese population using an electrochemical DNA array chip analysis. (PubMed id 17208375)1, 4, 9 Urata T....Inada T. (2007)
    68. Combined analysis of association between personality traits and three functional polymorphisms in the tyrosine hydroxylase, monoamine oxidase A, and catechol-O-methyltransferase genes. (PubMed id 16360899)1, 4, 9 Tochigi M....Sasaki T. (2006)
    69. Obesity is associated with genetic variants that alter dopamine availability. (PubMed id 16674552)1, 4, 9 Need A.C....Goldstein D.B. (2006)
    70. Family-based case-control study of MAOA and MAOB polymorphisms in Parkinson disease. (PubMed id 17044053)1, 4, 9 Kang S.J....Martin E.R. (2006)
    71. Association between monoamine oxidase gene polymorphisms and smoking behaviour in Chinese males. (PubMed id 16207390)1, 4, 9 Jin Y....Li L. (2006)
    72. Serotonin transporter, tryptophan hydroxylase, and monoamine oxidase A gene polymorphisms in premenstrual dysphoric disorder. (PubMed id 17026953)1, 4, 9 Magnay J.L....O'Brien S. (2006)
    73. Association of MAO A polymorphism and alcoholism in Brazilian females. (PubMed id 15900229)1, 4, 9 Guindalini C....Zatz M. (2005)
    74. Association analysis between a functional polymorphism in the monoamine oxidase A gene promoter and severe mood disorders. (PubMed id 15564894)1, 4, 9 Gutierrez B....Fananas L. (2004)
    75. MAO-A gene polymorphisms are associated with major depression and sleep disturbance in males. (PubMed id 15486489)1, 4, 9 Du L....Hrdina P.D. (2004)
    76. Pharmacogenetics of lithium prophylaxis in mood disorders: analysis of COMT, MAO-A, and Gbeta3 variants. (PubMed id 11992559)1, 4, 9 Serretti A....Smeraldi E. (2002)
    77. Additional evidence that genetic variation of MAO-A gene supports a gender subtype in obsessive-compulsive disorder. (PubMed id 11353450)1, 4, 9 Camarena B....Nicolini H. (2001)
    78. Polymorphic MAO-A and 5-HT-transporter genes: analysis of interactions in panic disorder. (PubMed id 12607224)1, 4, 9 Sand P....Deckert J. (2000)
    79. Association study of the serotoninergic system in mig raine in the Spanish population. (PubMed id 19455600)1, 4, 9 Corominas R....Cormand B. (2010)
    80. Gene-gene interaction between COMT and MAOA potential ly predicts the intelligence of attention-deficit hyperactivity disorder boys i n China. (PubMed id 19941049)1, 4, 9 Qian Q.J....Faraone S.V. (2010)
    81. Frequencies of genetic polymorphisms related to tript ans metabolism in chronic migraine. (PubMed id 20213484)1, 4, 9 Gentile G....Martelletti P. (2010)
    82. Associations between polymorphisms in dopamine neurot ransmitter pathway genes and pain response in healthy humans. (PubMed id 19796878)1, 4, 9 Treister R....Eisenberg E. (2009)
    83. No evidence for association between an MAOA functional polymorphism and susceptibility to Parkinson's disease. (PubMed id 19267171)1, 4, 9 Williams-Gray C....Barker R.A. (2009)
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    86. Resequencing of serotonin-related genes and association of tagging SNPs to citalopram response. (PubMed id 19077664)1, 4, 9 Peters E.J....Hamilton S.P. (2009)
    87. Single nucleotide polymorphisms in obesity-related ge nes and all-cause and cause-specific mortality: a prospective cohort study. (PubMed id 19818126)1, 4, 9 Gallicchio L....Helzlsouer K.J. (2009)
    88. MAOA-uVNTR polymorphism may modify the protective effect of ALDH2 gene against alcohol dependence in antisocial personality disorder. (PubMed id 19302089)1, 4, 9 Lee S.Y....Lu R.B. (2009)
    89. A polymorphism of the MAOA gene is associated with emotional brain markers and personality traits on an antisocial index. (PubMed id 19194374)1, 4, 9 Williams L.M....Gordon E. (2009)
    90. Candidate gene studies of ADHD: a meta-analytic revie w. (PubMed id 19506906)1, 4, 9 Gizer I.R....Waldman I.D. (2009)
    91. Association of MAOA gene functional promoter polymorphism with CSF dopamine turnover and atypical depression. (PubMed id 19214141)1, 4, 9 Aklillu E....Agren H. (2009)
    92. The interleukin-6, serotonin transporter, and monoami ne oxidase A genes and endurance performance during the South African Ironman T riathlon. (PubMed id 19935847)1, 4, 9 de Milander L....Collins M. (2009)
    93. Interactions between genotype and depressive symptoms on obesity. (PubMed id 19337825)1, 4, 9 Fuemmeler B.F....Ashley-Koch A.E. (2009)
    94. MAO-A and COMT genotypes as possible regulators of perinatal serotonergic symptoms after in utero exposure to SSRIs. (PubMed id 19223155)1, 4, 9 Hilli J....Laine K. (2009)
    95. A common variant in DRD3 gene is associated with risp eridone-induced extrapyramidal symptoms. (PubMed id 19506579)1, 4, 9 GassA^ P....Lafuente A. (2009)
    96. Brief report: aggression and stereotypic behavior in males with fragile X syndrome--moderating secondary genes in a 'single gene' disorder. (PubMed id 17340199)1, 4, 9 Hessl D....Hagerman R.J. (2008)
    97. Hyperserotonemia in autism: the potential role of 5HT-related gene variants. (PubMed id 18405062)1, 4, 9 Hranilovic D....Jernej B. (2008)
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    99. Cortical enlargement in autism is associated with a functional VNTR in the monoamine oxidase A gene. (PubMed id 18361446)1, 4, 9 Davis L.K....Wassink T.H. (2008)
    100. Interactions between genotype and retrospective ADHD symptoms predict lifetime smoking risk in a sample of young adults. (PubMed id 18188752)1, 4, 9 McClernon F.J....Ashley-Koch A.E. (2008)
    101. Lipid levels are associated with a regulatory polymorphism of the monoamine oxidase-A gene promoter (MAOA-uVNTR). (PubMed id 18227761)1, 4, 9 Brummett B.H....Williams R.B. (2008)
    102. HPA axis function in male caregivers: effect of the monoamine oxidase-A gene promoter (MAOA-uVNTR). (PubMed id 18639608)1, 4, 9 Brummett B.H....Williams R.B. (2008)
    103. The Genetics of Alzheimer's Disease in Brazil: 10 Years of Analysis in a Unique Population. (PubMed id 18607773)1, 4, 9 Oliveira J.R....Zatz M. (2008)
    104. 5-ht2c receptor and mao-a interaction analysis: no association with suicidal behaviour in bipolar patients. (PubMed id 18504633)1, 4, 9 De Luca V....Kennedy J.L. (2008)
    105. Monoamine oxidase A-uVNTR genotype affects limbic brain activity in response to affective facial stimuli. (PubMed id 18388730)1, 4, 9 Lee B.T. and Ham B.J. (2008)
    106. Association of dopamine transporter and monoamine oxidase molecular polymorphisms with sudden infant death syndrome and stillbirth: new insights into the serotonin hypothesis. (PubMed id 18810510)1, 4, 9 Filonzi L....Nonnis Marzano F. (2008)
    107. ADHD and Disruptive Behavior scores - associations with MAO-A and 5-HTT genes and with platelet MAO-B activity in adolescents. (PubMed id 18430257)1, 4, 9 Malmberg K....Larsson J.O. (2008)
    108. Association study of MAO-A and DRD4 genes in schizophrenic patients with aggressive behavior. (PubMed id 17657171)1, 4, 9 Fresan A....Nicolini H. (2007)
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    110. Gene-lifecourse interaction for alcohol consumption in adolescence and young adulthood: five monoamine genes. (PubMed id 17440951)1, 4, 9 Guo G....Hamilton N. (2007)
    111. The MAOA T941G polymorphism and short-term treatment response to mirtazapine and paroxetine in major depression. (PubMed id 17192957)1, 4, 9 Tadic A....Szegedi A. (2007)
    112. Association study between the monoamine oxidase A gene and attention deficit hyperactivity disorder in Taiwanese samples. (PubMed id 17328795)1, 4, 9 Xu X....Asherson P. (2007)
    113. Gene-environment interactions in parkinsonism and Parkinson's disease: the Geoparkinson study. (PubMed id 17449559)1, 4, 9 Dick F.D....Felice A. (2007)
    114. Association analysis of 15 polymorphisms within 10 candidate genes for antisocial behavioural traits. (PubMed id 17728669)1, 4, 9 Prichard Z.M....Easteal S. (2007)
    115. A linkage and family-based association analysis of a potential neurocognitive endophenotype of bipolar disorder. (PubMed id 17627031)1, 4, 9 Savitz J....Ramesar R. (2007)
    116. Association study between clinical response to rizatriptan and some candidate genes. (PubMed id 17563839)1, 4, 9 Asuni C....Stochino M.E. (2007)
    117. Associations of a regulatory polymorphism of monoamine oxidase-A gene promoter (MAOA-uVNTR) with symptoms of depression and sleep quality. (PubMed id 17585061)1, 4, 9 Brummett B.H....Williams R.B. (2007)
    118. Genetically increased risk of sleep disruption in Alzheimer's disease. (PubMed id 16944667)1, 4, 9 Craig D....Passmore A.P. (2006)
    119. An association study of catechol-O-methyltransferase and monoamine oxidase A polymorphisms and personality traits in Koreans. (PubMed id 16584839)1, 4, 9 Kim S.J....Kim C.H. (2006)
    120. The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: association signals in DRD4, DAT1 and 16 other genes. (PubMed id 16894395)1, 4, 9 Brookes K....Asherson P. (2006)
    121. A genetic association study of dopamine metabolism-related genes and chronic headache with drug abuse. (PubMed id 16930369)1, 4, 9 Cevoli S....Montagna P. (2006)
    122. Genetic polymorphisms in monoamine neurotransmitter systems show only weak association with acute post-surgical pain in humans. (PubMed id 16848906)1, 4, 9 Kim H....Dionne R.A. (2006)
    123. Monoamine oxidase A gene promoter polymorphism affects novelty seeking and reward dependence in healthy study participants. (PubMed id 16538181)1, 4, 9 Shiraishi H....Otani K. (2006)
    124. Gene-gene interaction between MAOA and COMT in suicidal behavior: analysis in schizophrenia. (PubMed id 16725119)1, 4, 9 De Luca V....Kennedy J.L. (2006)
    125. Temperament and character in mood disorders: influence of DRD4, SERTPR, TPH and MAO-A polymorphisms. (PubMed id 16319504)1, 4, 9 Serretti A....Cloninger C.R. (2006)
    126. The association of DNA sequence variation at the MAOA genetic locus with quantitative behavioural traits in normal males. (PubMed id 16896926)1, 4, 9 Rosenberg S....Skorecki K. (2006)
    127. Polymorphisms in genes regulating the HPA axis associated with empirically delineated classes of unexplained chronic fatigue. (PubMed id 16610949)1, 4, 9 Smith A.K....Rajeevan M.S. (2006)
    128. Interaction between MAO-A genotype and maltreatment in the risk for conduct disorder: failure to confirm in adolescent patients. (PubMed id 16741202)1, 4, 9 Young S.E....Crowley T.J. (2006)
    129. Monoamine oxidase-a genetic variations influence brain activity associated with inhibitory control: new insight into the neural correlates of impulsivity. (PubMed id 16202396)1, 4, 9 Passamonti L....Quattrone A. (2006)
    130. Associations between serotonin-related gene polymorphisms and panic disorder. (PubMed id 15670397)1, 4, 9 Maron E....Shlik J. (2005)
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    132. Association study of a monoamine oxidase a gene promoter polymorphism with major depressive disorder and antidepressant response. (PubMed id 15956990)1, 4, 9 Yu Y.W....Yang C.W. (2005)
    133. MAOA haplotypes associated with thrombocyte-MAO activity. (PubMed id 16174289)1, 4, 9 Jansson M....Pedersen N.L. (2005)
    134. Monoamine oxidase a polymorphism in Brazilian patients: risk factor for late-onset Alzheimer's disease? (PubMed id 16186632)1, 4, 9 Nishimura A.L....Zatz M. (2005)
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    136. Association study of a functional MAOA-uVNTR gene polymorphism and cognitive function in healthy females. (PubMed id 15990460)1, 4, 9 Yu Y.W....Chen T.J. (2005)
    137. Association analysis of the functional monoamine oxidase A gene promotor polymorphism in migraine. (PubMed id 15088153)1, 4, 9 Marziniak M....Sommer C. (2004)
    138. Association between serotonin-related genetic polymorphisms and CCK-4-induced panic attacks with or without 5-hydroxytryptophan pretreatment in healthy volunteers. (PubMed id 15346539)1, 4, 9 Maron E....Shlik J. (2004)
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    141. Association studies of MAO-A, COMT, and 5-HTT genes polymorphisms in patients with anxiety disorders of the phobic spectrum. (PubMed id 15450911)1, 4, 9 Samochowiec J....Kucharska-Mazur J. (2004)
    142. An association between a functional polymorphism in the monoamine oxidase a gene promoter, impulsive traits and early abuse experiences. (PubMed id 15150530)1, 4, 9 Huang Y.Y....Mann J.J. (2004)
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    149. Deliberate self-harm is associated with allelic variation in the tryptophan hydroxylase gene (TPH A779C), but not with polymorphisms in five other serotonergic genes. (PubMed id 12877392)1, 4, 9 Pooley E.C....Harrison P.J. (2003)
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    188. Polymorphisms in innate immunity genes and lung cancer risk in Xuanwei, China. (PubMed id 19170196)1, 4 Shen M....Lan Q. (2009)
    189. Neural mechanisms of anger regulation as a function o f genetic risk for violence. (PubMed id 19485616)1, 4 Alia-Klein N....Volkow N.D. (2009)
    190. A common variant in DRD3 receptor is associated with autism spectrum disorder. (PubMed id 19058789)1, 4 de Krom M....van Ree J.M. (2009)
    191. Gene-gene interactions of CYP2A6 and MAOA polymorphisms on smoking behavior in Chinese male population. (PubMed id 19415821)1, 4 Tang X....Chen D. (2009)
    192. Monoamine oxidase a promoter gene associated with pro blem behavior in adults with intellectual/developmental disabilities. (PubMed id 19642709)1, 4 May M.E....Kennedy C.H. (2009)
    193. Family- and population-based association studies of monoamine oxidase A and autism spectrum disorders in Korean. (PubMed id 19100789)1, 4 Yoo H.J....Kim S.A. (2009)
    194. MAOA-uVNTR and early physical discipline interact to influence delinquent behavior. (PubMed id 19951362)1, 4 Edwards A.C....Dick D.M. (2009)
    195. Parental care moderates the influence of MAOA-uVNTR genotype and childhood stressors on trait impulsivity and aggression in adult women. (PubMed id 19357553)1, 4 Kinnally E.L....Mann J.J. (2009)
    196. Interaction of prenatal exposure to cigarettes and MAOA genotype in pathways to youth antisocial behavior. (PubMed id 19255579)1, 4 Wakschlag L.S....Cook E.H. (2009)
    197. An association study of monoamine oxidase A (MAOA) gene polymorphism in methamphetamine psychosis. (PubMed id 19368859)1, 4 Nakamura K....Mori N. (2009)
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    200. Financial and psychological risk attitudes associated with two single nucleotide polymorphisms in the nicotine receptor (CHRNA4) gen e. (PubMed id 19693267)1, 4 Roe B.E....Papp A.C. (2009)
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    209. High-activity variants of the uMAOA polymorphism increase the risk for depression in a large primary care sample. (PubMed id 18626920)1, 4 Rivera M....Cervilla J.A. (2008)
    210. Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway. (PubMed id 18676680)1, 4 Hosgood H.D....Lan Q. (2008)
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    379. Psychopathy, PCL-R, and MAOA genotype as predictors o f violent reconvictions. (PubMed id 20850185)1 Tikkanen R....Virkkunen M. (2011)
    380. Prefrontal cortex lesions and MAO-A modulate aggressi on in penetrating traumatic brain injury. (PubMed id 21422455)1 Pardini M....Grafman J. (2011)
    381. Type A monoamine oxidase regulates life and death of n eurons in neurodegeneration and neuroprotection. (PubMed id 21971004)1 Naoi M....Akao Y. (2011)
    382. Association of the MAOA promoter uVNTR polymorphism w ith suicide attempts in patients with major depressive disorder. (PubMed id 21605465)1 Lung F.W....Lee M.B. (2011)
    383. Gene x disease interaction on orbitofrontal gray matt er in cocaine addiction. (PubMed id 21383264)1 Alia-Klein N....Goldstein R.Z. (2011)
    384. Transcriptional regulation and multiple functions of M AO genes. (PubMed id 21359973)1 Shih J.C....Chen K. (2011)
    385. Deviant peer affiliation and antisocial behavior: int eraction with Monoamine Oxidase A (MAOA) genotype. (PubMed id 21152968)1 Lee S.S. (2011)
    386. Monoamine oxidase and semicarbazide-sensitive amine o xidase kinetic analysis in mesenteric arteries of patients with type 2 diabetes . (PubMed id 21114364)1 Nunes S.F....Caramona M.M. (2011)
    387. Bimodal distribution of RNA expression levels in huma n skeletal muscle tissue. (PubMed id 21299892)1 Mason C.C....Bogardus C. (2011)
    388. Up-regulation of the isoenzymes MAO-A and MAO-B in th e human basal ganglia and pons in Huntington's disease revealed by quantitative enzyme radioautography. (PubMed id 21075085)1 Richards G....Saura J. (2011)
    389. Genetic susceptibility for individual cooperation pre ferences: the role of monoamine oxidase A gene (MAOA) in the voluntary provisio n of public goods. (PubMed id 21698196)1 Mertins V....Meyer J. (2011)
    390. Monoamine oxidases (MAO) in the pathogenesis of heart failure and ischemia/reperfusion injury. (PubMed id 20869994)7 Kaludercic N....Paolocci N. (2011)
    391. Association study of monoamine oxidase A/B genes and schizophrenia in Han Chinese. (PubMed id 21978760)1 Wei Y.L....Hu L. (2011)
    392. Structural properties of human monoamine oxidases A an d B. (PubMed id 21971000)1 Binda C....Edmondson D.E. (2011)
    393. MAO A VNTR polymorphism and amygdala volume in health y subjects. (PubMed id 21236646)1 Cerasa A....Spalletta G. (2011)
    394. MAOA-L carriers are better at making optimal financia l decisions under risk. (PubMed id 21147794)1 Frydman C....Rangel A. (2011)
    395. MAOA, DBH, and SLC6A4 variants in CHARGE: a case-cont rol study of autism spectrum disorders. (PubMed id 21538940)1 Tassone F....Hertz-Picciotto I. (2011)
    396. Cognitive effects of genetic variation in monoamine n eurotransmitter systems: a population-based study of COMT, MAOA, and 5HTTLPR. (PubMed id 21302344)1 Barnett J.H....Jones P.B. (2011)
    397. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    398. Association analysis between 12 genetic variants of t en genes and personality traits in a young chinese han population. (PubMed id 20464528)1 Gong P....Zhang F. (2010)
    399. Aggression, Digit Ratio and Variation in Androgen Rec eptor and Monoamine Oxidase A Genes in Men. (PubMed id 20967566)1 Hurd P.L....Dinsdale N.L. (2010)
    400. Search for association between suicide and 5-HTT, MAO A and DAT polymorphism in Polish males. (PubMed id 21516943)1 Linkowska K....Grzybowski T. (2010)
    401. MAOA genotype, family relations and sexual abuse in r elation to adolescent alcohol consumption. (PubMed id 20731636)1 Nilsson K.W....Oreland L. (2010)
    402. Targeting monoamine oxidase A in advanced prostate ca ncer. (PubMed id 20204405)1 Flamand V....Peehl D.M. (2010)
    403. Effects of age and MAOA genotype on the neural proces sing of social rejection. (PubMed id 20497231)1 Sebastian C.L....Blakemore S.J. (2010)
    404. Autism severity is associated with child and maternal MAOA genotypes. (PubMed id 20573161)1 Cohen I....Holden J. (2010)
    405. Poor replication of candidate genes for major depress ive disorder using genome-wide association data. (PubMed id 20351714)1 Bosker F.J....Nolen W.A. (2010)
    406. Deletion of MAOA and MAOB in a male patient causes se vere developmental delay, intermittent hypotonia and stereotypical hand movemen ts. (PubMed id 20485326)1 Whibley A....Raymond F.L. (2010)
    407. Cumulative-genetic plasticity, parenting and adolesce nt self-regulation. (PubMed id 21039487)1 Belsky J. and Beaver K.M. (2010)
    408. MAO-A promoter polymorphism and idiopathic pulmonary arterial hypertension. (PubMed id 21273708)1 Vadapalli S....Nallari P. (2010)
    409. Genetic determinants of time perception mediated by t he serotonergic system. (PubMed id 20862259)1 Sysoeva O.V....Wackermann J. (2010)
    410. Maltreatment, MAOA, and Delinquency: Sex Differences in Gene-Environment Interaction in a Large Population-Based Cohort of Adolescen ts. (PubMed id 20734127)1 Aslund C....Nilsson K.W. (2010)
    411. Mirtazapine abolishes hyperthermia in an animal model of serotonin syndrome. (PubMed id 20655983)7 Shioda K....Kato S. (2010)
    412. MAOA interacts with the ALDH2 gene in anxiety-depress ion alcohol dependence. (PubMed id 20477771)1 Lee S.Y....Lu R.B. (2010)
    413. A population-specific HTR2B stop codon predisposes to severe impulsivity. (PubMed id 21179162)2 Bevilacqua L.... Goldman D. (2010)
    414. Harsh discipline, childhood sexual assault, and MAOA genotype: an investigation of main and interactive effects on diverse clinical externalizing outcomes. (PubMed id 20364435)1 Derringer J....Iacono W.G. (2010)
    415. Identification and characterization of putative methy lation targets in the MAOA locus using bioinformatic approaches. (PubMed id 20421737)1 Shumay E. and Fowler J.S. (2010)
    416. Zonisamide: a new drug for Parkinson's disease. (PubMed id 20502722)7 Murata M. (2010)
    417. MAOA T941G polymorphism and the time course of emotio nal recovery following unpleasant pictures. (PubMed id 20374544)1 Larson C.L....Robinson J.S. (2010)
    418. Long-term administration of monoamine oxidase inhibit ors alters the firing rate and pattern of dopamine neurons in the ventral tegme ntal area. (PubMed id 18700056)7 Chenu F....Blier P. (2009)
    419. Antidepressant phenelzine alters differentiation of c ultured human and mouse preadipocytes. (PubMed id 19201819)7 Chiche F....FA"ve B. (2009)
    420. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (2009)
    421. Neighborhoods and genes and everything in between: un derstanding adolescent aggression in social and biological contexts. (PubMed id 19583892)1 Hart D. and Marmorstein N.R. (2009)
    422. A Bayesian approach to gene-gene and gene-environment interactions in chronic fatigue syndrome. (PubMed id 19102713)4 Lin E. and Hsu S.Y. (2009)
    423. Serotonin produces monoamine oxidase-dependent oxidat ive stress in human heart valves. (PubMed id 19666839)1 PeA+a-Silva R.A....Heistad D.D. (2009)
    424. Monoamine oxidase A gene (MAOA) associated with attit ude towards longshot risks. (PubMed id 20046877)1 Zhong S....Chew S.H. (2009)
    425. Biosocial influences on fraudulent behaviors. (PubMed id 19492728)1 Beaver K.M. and Holtfreter K. (2009)
    426. Cerebral monoamine oxidase A inhibition in tobacco sm okers confirmed with PET and [11C]befloxatone. (PubMed id 19142115)7 Leroy C....Trichard C. (2009)
    427. Association between monoamine oxidase A (MAOA) and personality traits in Japanese individuals. (PubMed id 18845200)1 Tsuchimine S....Kaneko S. (2008)
    428. MAOA and the neurogenetic architecture of human aggression. (PubMed id 18258310)1 Buckholtz J.W. and Meyer-Lindenberg A. (2008)
    429. Which genotype of MAO gene that the patients have are likely to be most susceptible to the symptoms of fibromyalgia? (PubMed id 17885758)1 Gursoy S....Sahin G. (2008)
    430. Phenelzine causes an increase in brain ornithine that is prevented by prior monoamine oxidase inhibition. (PubMed id 17768678)7 MacKenzie E.M....Wood P.L. (2008)
    431. Reduced activity of monoamine oxidase in the rat brai n following repeated nandrolone decanoate administration. (PubMed id 18539264)7 Birgner C....BergstrAPm L. (2008)
    432. Monoamine oxidase inactivation: from pathophysiology to therapeutics. (PubMed id 18652859)7 Bortolato M....Shih J.C. (2008)
    433. Comparison of the structural properties of the active site cavities of human and rat monoamine oxidase A and B in their soluble and membrane-bound forms. (PubMed id 18092818)1 Upadhyay A.K....Edmondson D.E. (2008)
    434. Proteomics analysis of the interactome of N-myc downstream regulated gene 1 and its interactions with the androgen response program in prostate cancer cells. (PubMed id 17220478)1 Tu L.C....Lin B. (2007)
    435. [Genetic polymorphism of a MAO in mental disorders] (PubMed id 18046979)1 Tylec A....Kucharska-Pietura K. (2007)
    436. The monoamine oxidase inhibitor phenelzine enhances t he discriminative stimulus effect of nicotine in rats. (PubMed id 17912044)7 Wooters T.E. and Bardo M.T. (2007)
    437. Pharmacokinetics and absolute bioavailability of sele giline following treatment of healthy subjects with the selegiline transdermal system (6 mg/24 h): a comparison with oral selegiline capsules. (PubMed id 17715422)7 Azzaro A.J....VanDenBerg C. (2007)
    438. A link between monoamine oxidase-A and apoptosis in serum deprived human SH-SY5Y neuroblastoma cells. (PubMed id 17393061)1 Fitzgerald J.C....Billett E.E. (2007)
    439. Calcium-sensitive regulation of monoamine oxidase-A contributes to the production of peroxyradicals in hippocampal cultures: implications for Alzheimer disease-related pathology. (PubMed id 17868476)1 Cao X....Mousseau D.D. (2007)
    440. Analysis of monoamine oxidase A promoter polymorphism in mentally retarded individuals. (PubMed id 17167335)1 Das Bhowmik A....Mukhopadhyay K. (2007)
    441. Amine oxidases and their inhibitors: what can they te ll us about neuroprotection and the development of drugs for neuropsychiatric d isorders? (PubMed id 17823646)7 Baker G.B....Todd K.G. (2007)
    442. Association between monoamine oxidase A polymorphisms and anger-related personality traits in Korean women. (PubMed id 17943028)1 Yang J.W....Ham B.J. (2007)
    443. The effect of antidepressants on glucose homeostasis and insulin sensitivity: synthesis and mechanisms. (PubMed id 16370964)7 McIntyre R.S....Kennedy S.H. (2006)
    444. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
    445. Linezolid and serotonergic drug interactions: a retro spective survey. (PubMed id 16779744)7 Taylor J.J....Estes L.L. (2006)
    446. How many drug targets are there? (PubMed id 17139284)7 Overington J.P....Hopkins A.L. (2006)
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    448. Monoallelic expression of MAOA in skin fibroblasts. (PubMed id 16890910)1 Nordquist N. and Oreland L. (2006)
    449. Effects of monoamine oxidase inhibitors on cocaine di scrimination in rats. (PubMed id 16495723)7 Gatch M.B....Forster M.J. (2006)
    450. Monoamine oxidase A and repressor R1 are involved in apoptotic signaling pathway. (PubMed id 16829576)1 Ou X.-M.... Shih J.C. (2006)
    451. Allelic mRNA expression of X-linked monoamine oxidase a (MAOA) in human brain: dissection of epigenetic and genetic factors. (PubMed id 16893905)1 Pinsonneault J.K....Sadee W. (2006)
    452. Parkin suppresses the expression of monoamine oxidases. (PubMed id 16455660)1 Jiang H....Feng J. (2006)
    453. Mechanisms of neurotransmitter release by amphetamine s: a review. (PubMed id 15955613)7 Sulzer D....Galli A. (2005)
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    455. The DNA sequence of the human X chromosome. (PubMed id 15772651)2 Ross M.T.... Bentley D.R. (2005)
    456. A review of linezolid: the first oxazolidinone antibi otic. (PubMed id 15482171)7 Stevens D.L....Madaras-Kelly K. (2004)
    457. Extracellular serotonin, dopamine and glutamate level s are elevated in the hypothalamus in a serotonin syndrome animal model induced by tranylcypromine and fluoxetine. (PubMed id 15276688)7 Shioda K....Kato S. (2004)
    458. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    459. Inhibitory effects of the monoamine oxidase inhibitor tranylcypromine on the cytochrome P450 enzymes CYP2C19, CYP2C9, and CYP2D6. (PubMed id 15049511)7 Salsali M....Baker G.B. (2004)
    460. Positive selection in MAOA gene is human exclusive: determination of the putative amino acid change selected in the human lineage. (PubMed id 15349769)1 Andres A.M....Bertranpetit J. (2004)
    461. Liquid chromatographic and tandem mass spectrometric assay for evaluation of in vivo inhibition of rat brain monoamine oxidases (MAO ) A and B following a single dose of MAO inhibitors: application of biomarkers in drug discovery. (PubMed id 15351283)7 Lang W....Rafferty B.M. (2004)
    462. MAOA and persistent, pervasive childhood aggression. (PubMed id 15024395)1 Beitchman J.H....Kennedy J.L. (2004)
    463. Identification of a furazolidone metabolite responsib le for the inhibition of amino oxidases. (PubMed id 12623758)7 Timperio A.M....Zolla L. (2003)
    464. Elucidating the role of genetic factors in smoking behavior and nicotine dependence. (PubMed id 12627466)4 Lerman C. and Berrettini W. (2003)
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    466. An in vitro interethnic comparison of monoamine oxida se activities between Japanese and Caucasian livers using rizatriptan, a seroto nin receptor 1B/1D agonist, as a model drug. (PubMed id 14651728)7 Iwasa T....Ishizaki T. (2003)
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    470. Clinical pharmacokinetics of intranasal sumatriptan. (PubMed id 12190330)7 Fuseau E....Ibbotson T. (2002)
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    476. Monoamine oxidase inhibition is unlikely to be releva nt to the risks associated with phentermine and fenfluramine: a comparison with their abilities to evoke monoamine release. (PubMed id 11673765)7 Kilpatrick I.C....Heal D.J. (2001)
    477. Characterization of phentermine and related compounds as monoamine oxidase (MAO) inhibitors. (PubMed id 10799660)7 Ulus I.H....Wurtman R.J. (2000)
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    479. No genetic linkage or association between a functional promoter polymorphism in the monoamine oxidase-A gene and panic disorder. (PubMed id 11032378)4 Hamilton S.P....Knowles J.A. (2000)
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    723. X-LRT: a likelihood approach to estimate genetic risks and test association with X-linked markers using a case-parents design. (PubMed id 18278816)9 Zhang L....Morris R.W. (2008)
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    728. Structural and mechanistic studies of arylalkylhydrazine inhibition of human monoamine oxidases A and B. (PubMed id 18426226)9 Binda C....Edmondson D.E. (2008)
    729. Serotonin metabolism is dysregulated in cholangiocarcinoma, which has implications for tumor growth. (PubMed id 19010890)9 Alpini G....DeMorrow S. (2008)
    730. Synthesis, structure-activity relationships and molecular modeling studies of new indole inhibitors of monoamine oxidases A and B. (PubMed id 18951803)9 La Regina G....Agostinelli E. (2008)
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    736. Identification of genes with correlated patterns of variations in DNA copy number and gene expression level in gastric cancer. (PubMed id 17229543)9 Yang S....Chung H.C. (2007)
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    738. Selegiline transdermal system: in the treatment of ma jor depressive disorder. (PubMed id 17284087)9 Frampton J.E. and Plosker G.L. (2007)
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    742. Serotonin mediates oxidative stress and mitochondrial toxicity in a murine model of nonalcoholic steatohepatitis. (PubMed id 17681180)9 Nocito A....Clavien P.A. (2007)
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    744. Factors affecting the relative importance of amine ox idases and monooxygenases in the in vivo metabolism of xenobiotic amines in hum ans. (PubMed id 17401530)9 Strolin Benedetti M....Baltes E. (2007)
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    746. Interactions of imidazoline ligands with the active site of purified monoamine oxidase A. (PubMed id 17480205)9 Jones T.Z....Ramsay R.R. (2007)
    747. Characterization of the covalently bound anionic flavin radical in monoamine oxidase a by electron paramagnetic resonance. (PubMed id 18044898)9 Kay C.W....Ramsay R.R. (2007)
    748. Renal albumin excretion: twin studies identify influences of heredity, environment, and adrenergic pathway polymorphism. (PubMed id 17353515)9 Rao F....O'Connor D.T. (2007)
    749. Bad nature, bad nurture, and testimony regarding MAOA and SLC6A4 genotyping at murder trials. (PubMed id 17944904)9 Bernet W....Montgomery S.A. (2007)
    750. Variations in activity and inhibition with pH: the protonated amine is the substrate for monoamine oxidase, but uncharged inhibitors bind better. (PubMed id 17401535)9 Jones T.Z....Ramsay R.R. (2007)
    751. Effects of a tyramine-enriched meal on blood pressure response in healthy male volunteers treated with selegiline transdermal system 6 mg/24 hour. (PubMed id 17192761)9 Blob L.F....Azzaro A.J. (2007)
    752. Structural insights into the mechanism of amine oxidation by monoamine oxidases A and B. (PubMed id 17573034)9 Edmondson D.E....Mattevi A. (2007)
    753. Evaluation of the potential for pharmacodynamic and pharmacokinetic drug interactions between selegiline transdermal system and two sympathomimetic agents (pseudoephedrine and phenylpropanolamine) in healthy volunteers. (PubMed id 17554106)9 Azzaro A.J....Campbell B.J. (2007)
    754. Nature and nurture predispose to violent behavior: serotonergic genes and adverse childhood environment. (PubMed id 17342170)9 Reif A....Retz W. (2007)
    755. Structural insights into monoamine oxidase inhibitory potency and selectivity of 7-substituted coumarins from ligand- and target-bas ed approaches. (PubMed id 16884303)9 Catto M....Carotti A. (2006)
    756. Metabolism of nomifensine to a dihydroisoquinolinium ion metabolite by human myeloperoxidase, hemoglobin, monoamine oxidase A, and c ytochrome P450 enzymes. (PubMed id 16679384)9 Obach R.S. and Dalvie D.K. (2006)
    757. Molecular mechanism of the relation of monoamine oxidase B and its inhibitors to Parkinson's disease: possible implications of glial cells. (PubMed id 17447416)9 Nagatsu T. and Sawada M. (2006)
    758. Estrogen-related receptors-stimulated monoamine oxidase B promoter activity is down-regulated by estrogen receptors. (PubMed id 16484337)9 Zhang Z....Teng C.T. (2006)
    759. Monoamine oxidase: isoforms and inhibitors in Parkinson's disease and depressive illness. (PubMed id 16402116)9 Youdim M.B. and Bakhle Y.S. (2006)
    760. Human monoamine oxidase enzyme inhibition by coffee and beta-carbolines norharman and harman isolated from coffee. (PubMed id 16139309)9 Herraiz T. and Chaparro C. (2006)
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    763. A molecular correlate to the Gleason grading system for prostate adenocarcinoma. (PubMed id 16829574)9 True L....Nelson P.S. (2006)
    764. Functional role of the 'aromatic cage' in human monoamine oxidase B: structures and catalytic properties of Tyr435 mutant proteins. (PubMed id 16605246)9 Li M....Edmondson D.E. (2006)
    765. Involvement of type A monoamine oxidase in neurodegeneration: regulation of mitochondrial signaling leading to cell death or neuroprotection. (PubMed id 17447417)9 Naoi M....Yamaoka Y. (2006)
    766. Design, synthesis, and biological evaluation of semicarbazide-sensitive amine oxidase (SSAO) inhibitors with anti-inflammatory activity. (PubMed id 16570912)9 Wang E.Y....Linnik M.D. (2006)
    767. Elevated monoamine oxidase a levels in the brain: an explanation for the monoamine imbalance of major depression. (PubMed id 17088501)9 Meyer J.H....Houle S. (2006)
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    771. The imidazoline I2-site ligands BU 224 and 2-BFI inhi bit MAO-A and MAO-B activities, hydrogen peroxide production, and lipolysis in rodent and human adipocytes. (PubMed id 17056035)9 Bour S....CarpAcnAc C. (2006)
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    774. Mechanistic pharmacokinetic and pharmacodynamic modeling of CHF3381 (2-[(2,3-dihydro-1H-inden-2-yl)amino]acetamide monohydrochloride), a novel N-methyl-D-aspartate antagonist and monoamine oxidase-A inhibitor in healthy subjects. (PubMed id 15671203)9 Csajka C....Verotta D. (2005)
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    776. Acute inhibition of cardiac monoamine oxidase A after tobacco smoke inhalation: validation study of [11C]befloxatone in rats followed by a positron emission tomography application in baboons. (PubMed id 15833896)9 Valette H....Syrota A. (2005)
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    781. Interdependent serotonin transporter and receptor pathways regulate S100A4/Mts1, a gene associated with pulmonary vascular disease. (PubMed id 16002749)9 Lawrie A....Rabinovitch M. (2005)
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    785. Human monoamine oxidase is inhibited by tobacco smoke: beta-carboline alkaloids act as potent and reversible inhibitors. (PubMed id 15582589)9 Herraiz T. and Chaparro C. (2005)
    786. A genetic analysis of serotonergic biosynthetic and metabolic enzymes in migraine using a DNA pooling approach. (PubMed id 16200390)9 Johnson M.P. and Griffiths L.R. (2005)
    787. Molecular characterization of monoamine oxidase in ze brafish (Danio rerio). (PubMed id 15621520)9 Setini A....Nicotra A. (2005)
    788. Fluorinated phenylcyclopropylamines. Part 4: effects of aryl substituents and stereochemistry on the inhibition of monoamine oxidases by 1-aryl-2-fluoro-cyclopropylamines. (PubMed id 15755651)9 Ye S....Kirk K.L. (2005)
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    790. Association analysis of the monoamine oxidase A and B genes with attention deficit hyperactivity disorder (ADHD) in an Irish sample: preferential transmission of the MAO-A 941G allele to affected children. (PubMed id 15717295)9 Domschke K....Hawi Z. (2005)
    791. Demonstration of isoleucine 199 as a structural determinant for the selective inhibition of human monoamine oxidase B by specific reversible inhibitors. (PubMed id 15710600)9 Hubalek F....Edmondson D.E. (2005)
    792. Genetic features of antidepressant induced mania and hypo-mania in bipolar disorder. (PubMed id 15248044)9 Serretti A....Catalano M. (2004)
    793. Uptake and metabolism of serotonin by ependymal primary cultures. (PubMed id 15453270)9 Verleysdonk S....Wellard J. (2004)
    794. Calcitonin gene-related peptide facilitates serotonin release from guinea-pig colonic mucosa via myenteric neurons and tachykinin NK2/NK3 receptors. (PubMed id 14718265)9 Kojima S....Kamikawa Y. (2004)
    795. Dopamine toxicity involves mitochondrial complex I inhibition: implications to dopamine-related neuropsychiatric disorders. (PubMed id 15130772)9 Ben-Shachar D....Ljubuncic P. (2004)
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    798. Effect of oral linezolid on the pressor response to i ntravenous tyramine. (PubMed id 15521893)9 Cantarini M.V....Hughes A.M. (2004)
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    800. Conserved elements of the cytochrome P-450 superfamily found in monoamine oxidase B. (PubMed id 14697882)9 Lewis D.A....Abell C.W. (2004)
    801. HPLC-based bioactivity profiling of plant extracts: a kinetic assay for the identification of monoamine oxidase-A inhibitors using human recombinant monoamine oxidase-A. (PubMed id 15501256)9 Dittmann K....Hamburger M. (2004)
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    810. Simple, potent, and selective pyrrole inhibitors of monoamine oxidase types A and B. (PubMed id 12620068)9 Silvestri R....Turini P. (2003)
    811. Experimental gene interaction studies with SERT mutant mice as models for human polygenic and epistatic traits and disorders. (PubMed id 14653307)9 Murphy D.L....Lesch K.P. (2003)
    812. Effects of human growth hormone (hrGH) treatment on amine metabolism in rats subjected to extensive small bowel resection. (PubMed id 12624735)9 Fogel W.A....Andrzejewski W. (2003)
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    814. Demonstration of high monoaminoxidase-A levels in neuroendocrine gastroenteropancreatic tumors in vitro and in vivo-tumor visualization using positron emission tomography with 11C-harmine. (PubMed id 12900293)9 Orlefors H....BergstrAPm M. (2003)
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    816. Activities of extract and constituents of Banisteriop sis caapi relevant to parkinsonism. (PubMed id 12895680)9 Schwarz M.J....Lees A.D. (2003)
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    820. Synthesis and in vivo imaging properties of [11C]befloxatone: a novel highly potent positron emission tomography ligand for mono-amine oxidase-A. (PubMed id 12729662)9 Dolle F....Bottlaender M. (2003)
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    833. In vitro biotransformation of the selective serotonin reuptake inhibitor citalopram, its enantiomers and demethylated metabolites by monoamine oxidase in rat and human brain preparations. (PubMed id 11840311)9 Kosel M....Baumann P. (2002)
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    835. Effect of TV3326, a novel monoamine-oxidase cholinesterase inhibitor, in rat models of anxiety and depression. (PubMed id 11889501)9 Weinstock M....Youdim M.B. (2002)
    836. Novel dual inhibitors of AChE and MAO derived from hydroxy aminoindan and phenethylamine as potential treatment for Alzheimer's disease. (PubMed id 12431053)9 Sterling J....Weinstock M. (2002)
    837. The pharmacokinetics of sumatriptan when administered with clarithromycin in healthy volunteers. (PubMed id 12017403)9 Moore K.H....Sale M. (2002)
    838. Moclobemide in the treatment of hot flashes in postme nopausal women. (PubMed id 12665046)9 Tarim E....Kuscu E. (2002)
    839. Analysis of ten candidate genes in autism by association and linkage. (PubMed id 11857571)9 Philippe A....Leboyer M. (2002)
    840. Monoamine oxidase A and B activities in embryonic chick hepatocytes: differential regulation by retinoic acid. (PubMed id 11979502)9 Nicotra A....Conti Devirgiliis L. (2002)
    841. Serotonergic pathway genes and subtypes of alcoholism: association studies. (PubMed id 11525423)9 Parsian A. and Cloninger C.R. (2001)
    842. Molecular genetics of bipolar disorder. (PubMed id 11377748)9 Kato T. (2001)
    843. Efficacy and tolerability of moclobemide in bulimia nervosa: a placebo-controlled trial. (PubMed id 11195257)9 Carruba M.O....Nisoli E. (2001)
    844. Coumarins derivatives as dual inhibitors of acetylcholinesterase and monoamine oxidase. (PubMed id 11543689)9 BrA1hlmann C....Carotti A. (2001)
    845. Inhibition of MAO-A fails to alter cocaine-induced increases in extracellular dopamine and norepinephrine in rat nucleus accumbens. (PubMed id 11245920)9 Pepper J.P....Rothman R.B. (2001)
    846. Effects of histamine H3-receptor ligands on brain monoamine oxidase in various mammalian species. (PubMed id 11430877)9 Sakurai E....Oreland L. (2001)
    847. Examining for association between candidate gene polymorphisms in the dopamine pathway and attention-deficit hyperactivity disorder: a family-based study. (PubMed id 11449400)9 Payton A....Thapar A. (2001)
    848. Combined treatment with corticosteroids and moclobemide favors normalization of hypothalamo-pituitary-adrenal axis dysregulation in relapsing-remitting multiple sclerosis: a randomized, double blind trial. (PubMed id 11297592)9 Then Bergh F....Trenkwalder C. (2001)
    849. Candidate gene studies of bipolar disorder. (PubMed id 11405546)9 Jones I. and Craddock N. (2001)
    850. Neurotransmitter dysfunction in hepatic encephalopathy: new approaches and new findings. (PubMed id 11726089)9 Butterworth R.F. (2001)
    851. Allelic variation of serotonin transporter expression is associated with depression in Parkinson's disease. (PubMed id 11326308)9 Mossner R....Lesch K.P. (2001)
    852. Cardiovascular sympathomimetic amine interactions in rats treated with monoamine oxidase inhibitors and the novel oxazolidinone antibiotic linezolid. (PubMed id 11336106)9 Humphrey S.J....Stryd R.P. (2001)
    853. Catecholamine monoamine oxidase a metabolite in adrenergic neurons is cytotoxic in vivo. (PubMed id 11164826)9 Burke W.J....Ruggiero D.A. (2001)
    854. [A behavioral and neurochemical study on the mechanis m of the anxiolytic effect of monoamine oxidase inhibitors] (PubMed id 11481866)9 Maki Y. (2001)
    855. Spectrometric evidence for the flavin-1-phenylcyclopropylamine inactivator adduct with monoamine oxidase N. (PubMed id 11331009)9 Mitchell D.J....Silverman R.B. (2001)
    856. Analysis of 4-methylthioamphetamine in clinical speci mens. (PubMed id 11471875)9 Elliott S.P. (2001)
    857. Production and metabolism of serotonin (5-HT) by the human adrenal cortex: paracrine stimulation of aldosterone secretion by 5-HT. (PubMed id 11600577)9 Lefebvre H....Kuhn J.M. (2001)
    858. Association studies of bipolar disorder. (PubMed id 11843779)9 Craddock N....Greening J. (2001)
    859. Effect of omeprazole on the pharmacokinetics of moclo bemide according to the genetic polymorphism of CYP2C19. (PubMed id 11309556)9 Yu K.S....Shin S.G. (2001)
    860. Predictors of treatment response in patients with posttraumatic stress disorder. (PubMed id 11294480)9 Connor K.M....Davidson J.R. (2001)
    861. Role of monoamine oxidase inhibition and monoamine de pletion in fenfluramine-induced neurotoxicity and serotonin release. (PubMed id 11881977)9 Halladay A.K....Wagner G.C. (2001)
    862. Non-MAO A binding of clorgyline in white matter in human brain. (PubMed id 11739617)9 Fowler J.S....Zhu W. (2001)
    863. Clinically significant drug interactions with agents specific for migraine attacks. (PubMed id 11460889)9 Eadie M.J. (2001)
    864. Mild learning difficulties and offending behaviour--is there a link with monoamine oxidase A deficiency? (PubMed id 11702062)9 Stamps V.R....Gurling H.M. (2001)
    865. Characterization of a major form of human isatin redu ctase and the reduced metabolite. (PubMed id 11722560)9 Usami N....Hara A. (2001)
    866. The covalent FAD of monoamine oxidase: structural and functional role and mechanism of the flavinylation reaction. (PubMed id 11761328)9 Edmondson D.E. and Newton-Vinson P. (2001)
    867. Molecular determinants of MAO selectivity in a series of indolylmethylamine derivatives: biological activities, 3D-QSAR/CoMFA analysis, and computational simulation of ligand recognition. (PubMed id 10794685)9 MorA^n J.A....Pardo L. (2000)
    868. A promoter polymorphism in the monoamine oxidase A gene and its relationships to monoamine metabolite concentrations in CSF of healthy volunteers. (PubMed id 10867119)9 JAPnsson E.G....Sedvall G.C. (2000)
    869. Inhibition of monoamine oxidases by functionalized coumarin derivatives: biological activities, QSARs, and 3D-QSARs. (PubMed id 11123983)9 Gnerre C....Testa B. (2000)
    870. Adrenergic and noradrenergic plasma levels in Lesch-Nyhan disease. (PubMed id 10693160)9 Ernst M....Cohen R.M. (2000)
    871. Use of PET in neuroendocrine tumors. In vivo applicat ions and in vitro studies. (PubMed id 10932603)9 Eriksson B....LAYngstrAPm B. (2000)
    872. Comparison of moclobemide with selective serotonin re uptake inhibitors (SSRIs) on sexual function in depressed adults. The Australia n and German Study Groups. (PubMed id 10974600)9 Philipp M....Kohnen R. (2000)
    873. A randomized, double-blind placebo-controlled trial of moclobemide in patients with chronic fatigue syndrome. (PubMed id 11030484)9 Hickie I.B....Lloyd A.R. (2000)
    874. The FAD binding sites of human liver monoamine oxidases A and B: investigation of the role of flavin ribityl side chain hydroxyl groups in the covalent flavinylation reaction and catalytic activities. (PubMed id 10606764)9 Miller J.R....Edmondson D.E. (2000)
    875. [The influence of genes on the development of personality] (PubMed id 10853361)9 Samochowiec J....Horodnicki J. (2000)
    876. An association between a polymorphism of the tryptophan hydroxylase gene and aggression in schizophrenia and schizoaffective disorder. (PubMed id 11204346)9 Nolan K.A....Saito T. (2000)
    877. Transport and metabolism of serotonin in the human placenta from normal and severely pre-eclamptic pregnancies. (PubMed id 10729753)9 Carrasco G....GonzA!lez C. (2000)
    878. [Seasonal characteristics of the monoaminergic regula tion of the behavior of hibernating animals] (PubMed id 11081224)9 Semenova T.P....Kolaeva S.G. (2000)
    879. [Study on molecular mechanism of ganyang shangkang syndrome in hypertension] (PubMed id 11783321)9 Jin Y....Yan D. (2000)
    880. Variability and validity of polymorphism association studies in Parkinson's disease. (PubMed id 10953187)9 Tan E.K....Ashizawa T. (2000)
    881. Genetic associations with clinical characteristics in bipolar affective disorder and recurrent unipolar depressive disorder. (PubMed id 10686549)9 Ho L.W....Rubinsztein D.C. (2000)
    882. Complications of cirrhosis III. Hepatic encephalopathy. (PubMed id 10728803)9 Butterworth R.F. (2000)
    883. Rasagiline, a monoamine oxidase-B inhibitor, protects NGF-differentiated PC12 cells against oxygen-glucose deprivation. (PubMed id 10518120)9 Abu-Raya S....Lazarovici P. (1999)
    884. Moclobemide treatment in multiple sclerosis patients with comorbid depression: an open-label safety trial. (PubMed id 10334000)9 Barak Y....Achiron A. (1999)
    885. Monoamine oxidase: from genes to behavior. (PubMed id 10202537)9 Shih J.C....Ridd M.J. (1999)
    886. Sixth World Congress of Psychiatric Genetics X Chromosome Workshop. (PubMed id 10374746)9 Paterson A.D. (1999)
    887. Social anxiety disorder: designing a pharmacologic treatment strategy. (PubMed id 10335676)9 Pollack M.H. (1999)
    888. Regulation of heme oxygenase-1 expression by dopamine in cultured C6 glioma and primary astrocytes. (PubMed id 10581397)9 Schmidt J....Morgan J.I. (1999)
    889. Benzylamine analog binding studies as probes of the substrate sites of monoamine oxidases A and B. (PubMed id 10065374)9 Edmondson D.E. (1999)
    890. Structure-activity relationships in the oxidation of para-substituted benzylamine analogues by recombinant human liver monoamine oxidase A. (PubMed id 10521274)9 Miller J.R. and Edmondson D.E. (1999)
    891. Species-dependent differences in monoamine oxidase A and B-catalyzed oxidation of various C4 substituted 1-methyl-4-phenyl-1,2,3, 6- tetrahydropyridinyl derivatives. (PubMed id 10525109)9 Inoue H....Castagnoli N. (1999)
    892. Social phobia: diagnosis, severity and implications for treatment. (PubMed id 10361959)9 Montgomery S.A. (1999)
    893. Pharmacokinetics of Hoasca alkaloids in healthy human s. (PubMed id 10404423)9 Callaway J.C....Mash D.C. (1999)
    894. Befloxatone (Synthelabo). (PubMed id 16160936)9 Emilien G. (1999)
    895. Switching to moclobemide to reverse fluoxetine-induce d sexual dysfunction in patients with depression. (PubMed id 9987207)9 Ramasubbu R. (1999)
    896. Moclobemide in patients with dementia and depression. (PubMed id 10410765)9 Amrein R....Cameron A.M. (1999)
    897. Inversion of selectivity of N-substituted propargylamine monoamine oxidase inhibitors following structural modifications to quaternary salts. (PubMed id 10641793)9 Yu P.H. and Davis B.A. (1999)
    898. Dysthymia: clinical picture, extent of overlap with chronic fatigue syndrome, neuropharmacological considerations, and new therapeutic vistas. (PubMed id 10357046)9 Brunello N....Wessely S. (1999)
    899. Imaging the neurochemistry of nicotine actions: studi es with positron emission tomography. (PubMed id 11768169)9 Volkow N.D....Gatley S.J. (1999)
    900. Hepatic encephalopathy: An update of pathophysiologic mechanisms. (PubMed id 10564534)9 Hazell A.S. and Butterworth R.F. (1999)
    901. A reversible monoamine oxidase A inhibitor, befloxatone: structural approach of its mechanism of action. (PubMed id 10482460)9 Wouters J....Durant F. (1999)
    902. Unified approach to the analysis of genetic variation in serotonergic pathways. (PubMed id 10581480)9 Marshall S.E.... Welsh K.I. (1999)
    903. MAO-A and -B gene knock-out mice exhibit distinctly different behavior. (PubMed id 10591056)9 Shih J.C. and Chen K. (1999)
    904. Inhibition of monoamine oxidase by pirlindole analogu es: 3D-QSAR analysis. (PubMed id 10591049)9 Medvedev A.E....Axenova L.N. (1999)
    905. In vivo and in vitro evidence for hydrogen peroxide (H2O2) accumulation in the epidermis of patients with vitiligo and its successful removal by a UVB-activated pseudocatalase. (PubMed id 10537016)9 Schallreuter K.U....Hibberts N.A. (1999)
    906. Effects of aging and glucocorticoid treatment on mono amine oxidase subtypes in rat cerebral cortex: therapeutic implications. (PubMed id 9886786)9 Slotkin T.A....Ritchie J.C. (1998)
    907. The monoamine oxidase-A gene and major psychosis in Japanese subjects. (PubMed id 9807650)9 Sasaki T....Nanko S. (1998)
    908. Allelic association between dinucleotide repeats at t he monoamine oxidase loci and schizophrenia. (PubMed id 19698656)9 Wei J. and Hammings G. (1998)
    909. Serotonin syndrome: history and risk. (PubMed id 9794145)9 Gillman P.K. (1998)
    910. Monoamine oxidase activities in human cystic and colonic arteries--influence of age. (PubMed id 9564621)9 Figueiredo I.V....Callingham B.A. (1998)
    911. A higher frequency of a low activity-related allele of the MAO-A gene in females with obsessive-compulsive disorder. (PubMed id 9861646)9 Camarena B....Nicolini H. (1998)
    912. Experience with tranylcypromine in early Parkinson's disease. (PubMed id 9564607)9 Fahn S. and Chouinard S. (1998)
    913. Comparison of the effects of moclobemide and selegiline on tyramine-evoked mydriasis in man. (PubMed id 9663810)9 Bitsios P....Bradshaw C.M. (1998)
    914. Norepinephrine transmitter metabolite generates free radicals and activates mitochondrial permeability transition: a mechanism for DOPEGAL-induced apoptosis. (PubMed id 9518674)9 Burke W.J....Lin T.S. (1998)
    915. Detection and analysis of four polymorphic markers at the human monoamine oxidase (MAO) gene in Japanese controls and patients with Parkinson's disease. (PubMed id 9642149)9 Nakatome M....Honda K. (1998)
    916. Placebo-controlled trial of moclobemide in social phobia. (PubMed id 9534836)9 Schneier F.R....Liebowitz M.R. (1998)
    917. Clinical pharmacology of befloxatone: a brief review. (PubMed id 10333984)9 Rosenzweig P....Legangneux E. (1998)
    918. Selective inhibitors of monoamine oxidase (MAO). 5. 1 -Substituted phenoxathiin inhibitors containing no nitrogen that inhibit MAO A by binding it to a hydrophobic site. (PubMed id 9622553)9 Harfenist M....White H.L. (1998)
    919. Type B monoamine oxidase activity in human brain malignant tumors. (PubMed id 10072212)9 Marcozzi G....MondovA- B. (1998)
    920. [Change of tryptophan hydroxylase and monoamine oxidase A activities in experimental depression induced by social confrontation] (PubMed id 9891212)9 Avgustinovich D.F....Kudriavtseva N.N. (1998)
    921. The influence of the antidepressant pirlindole and its dehydro-derivative on the activity of monoamine oxidase A and GABAA receptor binding. (PubMed id 9564636)9 Medvedev A.E....Squires R.F. (1998)
    922. Evaluation of efficacies of different classes of anti depressants in the forced swimming test in mice at different ages. (PubMed id 9608606)9 Bourin M....Baker G.B. (1998)
    923. Regional and molecular separation of the four bioactivities of 'tribulin'. (PubMed id 9488167)9 Hucklebridge F....Clow A. (1998)
    924. Alterations of neurotransmitter-related gene expression in human and experimental portal-systemic encephalopathy. (PubMed id 10206825)9 Butterworth R.F. (1998)
    925. Inhibition of monoamine oxidase by pirlindole analogues: 3D-QSAR and CoMFA analysis. (PubMed id 9845968)9 Medvedev A.E....Ivanov A.S. (1998)
    926. Role of monoamine oxidase type A and B on the dopamin e metabolism in discrete regions of the primate brain. (PubMed id 9704592)9 Lakshmana M.K....Raju T.R. (1998)
    927. An open trial of moclobemide in the treatment of post-traumatic stress disorder. (PubMed id 9347385)9 Neal L.A....Fox C. (1997)
    928. [Poisoning with a reversible and selective monoaminoo xidase inhibitor] (PubMed id 9273760)9 Pall M....Eriksen N.D. (1997)
    929. Increased stress response and beta-phenylethylamine i n MAOB-deficient mice. (PubMed id 9326944)9 Grimsby J....Shih J.C. (1997)
    930. The olfactory bulbectomized rat as a model of depress ion: an update. (PubMed id 9352586)9 Kelly J.P....Leonard B.E. (1997)
    931. Quantitation of low abundance mRNAs in glial cells us ing different polymerase chain reaction (PCR)-based methods. (PubMed id 9385056)9 Santagati S....Maggi A. (1997)
    932. Serotonin syndrome and drug combinations: focus on MAOI and RIMA. (PubMed id 9224903)9 Hilton S.E....MAPller H.J. (1997)
    933. Brofaromine versus imipramine in in-patients with maj or depression--a controlled trial. (PubMed id 9241569)9 Volz H.P....MAPller H.J. (1997)
    934. Pressor response to tyramine after single 24-hour application of a selegiline transdermal system in healthy males. (PubMed id 9089426)9 Barrett J.S....DiSanto A.R. (1997)
    935. Moclobemide and imipramine in chronic depression (dysthymia): an international double-blind, placebo-controlled trial. International Collaborative Study Group. (PubMed id 9347378)9 Versiani M....Stabl M. (1997)
    936. Moclobemide for anxiety disorders: a focus on moclobe mide for panic disorder. (PubMed id 9466172)9 Tiller J.W....Behnke K. (1997)
    937. [Inhibitory monoamine oxidases of the new generation] (PubMed id 9432289)9 Nowakowska E. and Chodera A. (1997)
    938. [Preventive treatment of migraine and chronic tension headache with moclobemide] (PubMed id 9324719)9 Meienberg O. and Amsler F. (1997)
    939. Inhibition of monoamine oxidase A by beta-carboline derivatives. (PubMed id 8990278)9 Kim H....Ramsay R.R. (1997)
    940. Clonality analysis in tumours of women by PCR amplifi cation of X-linked genes. (PubMed id 9120730)9 Peng H....Pan L. (1997)
    941. A fatality due to moclobemide. (PubMed id 9304853)9 Camaris C. and Little D. (1997)
    942. Synthesis, conformational analysis and antidepressant activity of moclobemide new analogues. (PubMed id 9112832)9 Ghanbarpour A....Rashidi-Ranjbar P. (1997)
    943. Increased density of catalytic sites and expression of brain monoamine oxidase A in humans with hepatic encephalopathy. (PubMed id 9048767)9 Mousseau D.D....Butterworth R.F. (1997)
    944. Antidepressant use in the elderly. Current status of nefazodone, venlafaxine and moclobemide. (PubMed id 9259175)9 Goldberg R.J. (1997)
    945. Monoamine oxidase genes polymorphisms and mood disorder. (PubMed id 9342198)9 Muramatsu T....Asai M. (1997)
    946. [Monoamine oxidase inhibitors and pressor response to dietary amines] (PubMed id 9503566)9 Tipton K.F. (1997)
    947. Altered catecholamine synthesis and degradation in the epidermis of patients with atopic eczema. (PubMed id 9452885)9 Schallreuter K.U....BA1ttner G. (1997)
    948. Treatment of depression in Parkinson's disease with moclobemide: A pilot open-label study. (PubMed id 18591080)9 GimAcnez-RoldA!n S....Mateo D. (1997)
    949. Formation of formaldehyde from adrenaline in vivo; a potential risk factor for stress-related angiopathy. (PubMed id 9131641)9 Yu P.H....Zuo D.M. (1997)
    950. Effects of past history of major depression on smoking characteristics, monoamine oxidase-A and -B activities and withdrawal symptoms in dependent smokers. (PubMed id 9179504)9 Berlin I....Launay J.M. (1997)
    951. Evaluation of four candidate genes encoding proteins of the dopamine pathway in familial and sporadic Parkinson's disease: evidence for association of a DRD2 allele. (PubMed id 9191771)9 Plante-Bordeneuve V....Harding A.E. (1997)
    952. Increased monoamine oxidase A activity in the epidermis of patients with vitiligo. (PubMed id 8750929)9 Schallreuter K.U....Ehrke C. (1996)
    953. Epidural anaesthesia, ephedrine and phenylephrine in a patient taking moclobemide, a new monoamine oxidase inhibitor. (PubMed id 9038453)9 Martyr J.W. and Orlikowski C.E. (1996)
    954. Pharmacodynamics and pharmacokinetics of two dose regimens of befloxatone, a new reversible and selective monoamine oxidase inhibitor, at steady state in healthy volunteers. (PubMed id 8690815)9 Patat A....Rosenzweig P. (1996)
    955. [Tribulin--a novel endogenous monoaminoxidase inhibit or (dedicated to the memory of Merton Sandler)] (PubMed id 9148606)9 Medvedev A.R. (1996)
    956. Human anti-mitochondria autoantibodies appearing in i proniazid-induced immunoallergic hepatitis recognize human liver monoamine oxid ase B. (PubMed id 8573115)9 Pons C....Mansuy D. (1996)
    957. Direct analysis of candidate genes in impulsive behaviours. (PubMed id 8862874)9 Goldman D....Ozaki N. (1996)
    958. Functional characterization of 5-HT1D autoreceptors on the modulation of 5-HT release in guinea-pig mesencephalic raphe, hippocampus and frontal cortex. (PubMed id 8762094)9 el Mansari M. and Blier P. (1996)
    959. Monoamine oxidase inhibitors. An update on drug inter actions. (PubMed id 8713690)9 Livingston M.G. and Livingston H.M. (1996)
    960. A double-blind randomized placebo-controlled study of the efficacy and safety of pirlindole, a reversible monoamine oxidase A inhibitor, in the treatment of depression. (PubMed id 9020990)9 De Wilde J.E....GAcczy J. (1996)
    961. Moclobemide versus fluoxetine for double depression: a randomized double-blind study. (PubMed id 9023788)9 Duarte A....Delini-Stula A. (1996)
    962. The pharmacotherapy of social phobia. (PubMed id 8923113)9 Pollack M.H. and Gould R.A. (1996)
    963. Drug treatment of depression in the 1990s. An overvie w of achievements and future possibilities. (PubMed id 9118813)9 MAPller H.J. and Volz H.P. (1996)
    964. Influence of age, frailty and liver function on the p harmacokinetics of brofaromine. (PubMed id 8866634)9 Zeeh J....Platt D. (1996)
    965. No evidence of linkage between schizophrenia and D2 dopamine receptor gene locus in Italian pedigrees. (PubMed id 8710185)9 Grassi E....Sorbi S. (1996)
    966. Tyramine pharmacodynamics during combined administrat ion of lazabemide and moclobemide. (PubMed id 8861736)9 Dingemanse J....Korn A. (1996)
    967. The role of cytochrome P450 2D6 in the metabolism of moclobemide. (PubMed id 8880082)9 HAortter S....Hiemke C. (1996)
    968. Genetic elevation of monoamine oxidase levels in dopa minergic PC12 cells results in increased free radical damage and sensitivity to MPTP. (PubMed id 8978500)9 Wei Q....Andersen J.K. (1996)
    969. Monoamine oxidase-dependent metabolism of dopamine in the striatum and substantia nigra of L-DOPA-treated monkeys. (PubMed id 8949927)9 Di Monte D.A....Langston J.W. (1996)
    970. [Serotonin syndrome in acute poisoning with antidepressive agents] (PubMed id 9033760)9 Robert P....Cathala B. (1996)
    971. A study of monoamine oxidase activity in fetal membra nes. (PubMed id 8677764)9 Sekizawa A....Oguchi K. (1996)
    972. Brofaromine--a review of its pharmacological properti es and therapeutic use. (PubMed id 9026374)9 Volz H.P....MAPller H.J. (1996)
    973. Different modes of data processing and statistical te sting applied to the same set of pharmaco-EEG recordings: effects on the evalua tion of a selective and reversible MAO A inhibitor (brofaromine). (PubMed id 8776746)9 Reimann I.W....Herrmann W.M. (1996)
    974. Moclobemide in the treatment of social phobia. (PubMed id 8923114)9 Nutt D. and Montgomery S.A. (1996)
    975. Species differences in the interactions of the anticonvulsant milacemide and some analogues with monoamine oxidase-B. (PubMed id 7646533)9 O'Brien E.M....Tipton K.F. (1995)
    976. Serotonin receptors. Genetic insights into serotonin function. (PubMed id 8542294)9 Heath M.J. and Hen R. (1995)
    977. Effect of aging on lazabemide binding, monoamine oxidase activity and monoamine metabolites in human frontal cortex. (PubMed id 8695059)9 Galva M.D....Picotti G.B. (1995)
    978. A reversible monoamine oxidase A inhibitor (moclobemi de) facilitates smoking cessation and abstinence in heavy, dependent smokers. (PubMed id 7586937)9 Berlin I....Puech A.J. (1995)
    979. Reversible and selective inhibitors of monoamine oxid ase A in mental and other disorders. (PubMed id 7717094)9 Priest R.G....Steinert J. (1995)
    980. A risk-benefit assessment of moclobemide in the treatment of depressive disorders. (PubMed id 7741983)9 Norman T.R. and Burrows G.D. (1995)
    981. A controlled double-blind trial of moclobemide and im ipramine in the treatment of depression. (PubMed id 7570133)9 Kok L.P. and Tsoi W.F. (1995)
    982. Dopaminergic and serotonergic neurotransmitters in bone marrow transplant patients. (PubMed id 7544403)9 Davis D.G. and Sparks D.L. (1995)
    983. Recent advances in geriatric psychopharmacology. (PubMed id 8535049)9 Naranjo C.A....Bremner K.E. (1995)
    984. Moclobemide safety: monitoring a newly developed prod uct in the 1990s. (PubMed id 7593735)9 Hilton S....Ruch R. (1995)
    985. Social phobia: the clinical efficacy and tolerability of the monoamine oxidase -A and serotonin uptake inhibitor brofaromine. A double-blind placebo-controlled study. (PubMed id 8619339)9 FahlAcn T....Pauli U. (1995)
    986. Inhibition of mitochondrial complexes I and IV by 6-hydroxydopamine. (PubMed id 7796873)9 Glinka Y.Y. and Youdim M.B. (1995)
    987. Moclobemide versus clomipramine in nonmelancholic, nonpsychotic major depression. A Study group. (PubMed id 8848950)9 Lecrubier Y....Stabl M. (1995)
    988. Redox properties of the flavin cofactor of monoamine oxidases A and B and their relationship to the kinetic mechanism. (PubMed id 8584669)9 Ramsay R.R....Singer T.P. (1995)
    989. Studies of reversible and selective inhibitors of monoamine oxidase A in dysthymia. (PubMed id 7717093)9 PActursson H. (1995)
    990. Relevance of reversible inhibitors of monoamine oxida se type A and of reuptake inhibition for noradrenaline turnover. (PubMed id 7717090)9 Hartmann D....Amrein R. (1995)
    991. Effect of initial treatment with antidepressants as a predictor of outcome after 8 weeks. (PubMed id 8570762)9 Volz H.P....MAPller H.J. (1995)
    992. Moclobemide in chronic neuropathic pain: preliminary case reports. (PubMed id 7549169)9 Menkes D.B....Jones D. (1995)
    993. L-dopa cytotoxicity to PC12 cells in culture is via i ts autoxidation. (PubMed id 7830076)9 Basma A.N....Geller H.M. (1995)
    994. Platelet and brain GABA-transaminase and monoamine oxidase activities in patients with complex partial seizures. (PubMed id 7750512)9 Kumlien E....Oreland L. (1995)
    995. Treatment of vitiligo with a topical application of p seudocatalase and calcium in combination with short-term UVB exposure: a case s tudy on 33 patients. (PubMed id 7599386)9 Schallreuter K.U....Levenig C. (1995)
    996. Monoamine oxidase A and B activities in heavy smokers. (PubMed id 8580230)9 Berlin I....Puech A.J. (1995)
    997. Clinical efficacy of reversible and selective inhibitors of monoamine oxidase A in major depression. (PubMed id 7717091)9 Paykel E.S. (1995)
    998. Norrie disease and MAO genes: nearest neighbors. (PubMed id 8541872)9 Chen Z.Y....Breakefield X.O. (1995)
    999. [The effect of pyrazidole on monoamine level in hypobaric hypoxia] (PubMed id 8122400)9 Goroshinskaia I.A....Sorokina I.V. (1994)
    1000. Characterization of the enzyme responsible for the me tabolism of sumatriptan in human liver. (PubMed id 8161354)9 Dixon C.M....Tarbit M.H. (1994)
    1001. Multicenter double-blind study of moclobemide and map rotiline. (PubMed id 7954483)9 Vaz-Serra A....Pestana L.C. (1994)
    1002. A cross-study comparison of the effects of moclobemid e and brofaromine on actual driving performance and estimated sleep. (PubMed id 7954488)9 Ramaekers J.G....O'Hanlon J.F. (1994)
    1003. In vivo effects of the monoamine oxidase inhibitors Ro 41-1049 and Ro 19-6327 on the production and fate of renal dopamine. (PubMed id 7931252)9 Vieira-Coelho M.A....Soares-da-Silva P. (1994)
    1004. Selective MAO-A and B inhibitors, radical scavengers and nitric oxide synthase inhibitors in Parkinson's disease. (PubMed id 7527888)9 Youdim M.B. and Lavie L. (1994)
    1005. Brofaromine in non-endogenous major depressed inpatie nts--results of a preliminary dose-finding trial versus tranylcypromine. (PubMed id 7972347)9 Volz H.P....MAPller H.J. (1994)
    1006. Correlations of plasma and urinary phenylacetic acid and phenylethylamine concentrations with eating behavior and mood rating scores in brofaromine-treated women with bulimia nervosa. (PubMed id 7918350)9 Davis B.A....Boulton A.A. (1994)
    1007. Experimental and theoretical study of reversible monoamine oxidase inhibitors: structural approach of the active site of the enzyme. (PubMed id 7931244)9 Wouters J....Jarreau F.X. (1994)
    1008. Modulation of 5-HT release in the guinea-pig brain following long-term administration of antidepressant drugs. (PubMed id 7834200)9 Blier P. and Bouchard C. (1994)
    1009. Biogenic amine metabolite patterns in the urine of mo noamine oxidase A-deficient patients. A possible tool for diagnosis. (PubMed id 7807947)9 Abeling N.G....Brunner H.G. (1994)
    1010. Moclobemide for depression. (PubMed id 7635005)9 (1994)
    1011. Effects of monoamine oxidase A inhibition on plasma biogenic amine metabolites in depressed patients. (PubMed id 7527564)9 Markianos M....Stefanis C. (1994)
    1012. Interaction of tetrahydrostilbazoles with monoamine o xidase A and B. (PubMed id 8289189)9 Sablin S.O....Tkachenko S.E. (1994)
    1013. Monoamine oxidase inhibitors, cognitive functions and neurodegenerative diseases. (PubMed id 7931235)9 Delumeau J.C....Allain H. (1994)
    1014. Novel 4-(aryloxy)tetrahydropyridine analogs of MPTP a s monoamine oxidase A and B substrates. (PubMed id 8151621)9 Kalgutkar A.S....Castagnoli N. (1994)
    1015. Inhibition of monoamine oxidase by clorgyline analogues. (PubMed id 7931241)9 O'Brien E.M....Dostert P. (1994)
    1016. Comparison of the efficacy and tolerability of moclob emide and maprotiline in depressed patients treated by general practitioners. (PubMed id 7954482)9 Gachoud J.P....KAPhler M. (1994)
    1017. Identification of human monoamine oxidase (MAO) A and B gene promoters. (PubMed id 7931237)9 Shih J.C....Chen K. (1994)
    1018. Moclobemide (Aurorix) in primary major depression. (PubMed id 8208985)9 Rihmer Z....GA!bor A. (1994)
    1019. (-)-Deprenyl reduces PC12 cell apoptosis by inducing new protein synthesis. (PubMed id 7931312)9 Tatton W.G....Kwan M. (1994)
    1020. Modulation of capsaicin induced airway reflexes in hu mans: effect of monoamine oxidase inhibition. (PubMed id 8443037)9 Choudry N.B....Fuller R.W. (1993)
    1021. Is there a role for selective monoamine oxidase inhib itor therapy in bulimia nervosa? A placebo-controlled trial of brofaromine. (PubMed id 8120155)9 Kennedy S.H....Lofchy J. (1993)
    1022. [An increase in the radioprotective effect of O-methyltyramine and mezaton by monoamine oxidase inhibitors] (PubMed id 8469735)9 KulinskiA- V.I....Rumiantseva N.P. (1993)
    1023. Integrative transporter-mediated release from cytopla smic and vesicular 5-hydroxytryptamine stores in cultured neurons. (PubMed id 8100196)9 Gu X.F. and Azmitia E.C. (1993)
    1024. Double-blind comparison of moclobemide and tranylcypr omine in depression. (PubMed id 8127928)9 Heinze G....Allen S.R. (1993)
    1025. Drug interactions with reversible monoamine oxidase-A inhibitors. (PubMed id 8313396)9 Callingham B.A. (1993)
    1026. Reversible monoamine oxidase-A inhibitors in resistant major depression. (PubMed id 8313400)9 Nolen W.A....Haffmans P.M. (1993)
    1027. Increased activities of MAOA and MAOB in autopsied brain tissue from cirrhotic patients with hepatic encephalopathy. (PubMed id 8242348)9 Rao V.L....Butterworth R.F. (1993)
    1028. The effect of side chain substitution at positions 2 and 3 of the heterocyclic ring of N-acetylenic analogues of tryptamine as monoamine oxidase inhibitors. (PubMed id 8517863)9 Avila M....Unzeta M. (1993)
    1029. Substrate-specific enhancement of the oxidative half-reaction of monoamine oxidase. (PubMed id 8443155)9 Tan A.K. and Ramsay R.R. (1993)
    1030. Serotonin uptake inhibition by the monoamine oxidase inhibitor brofaromine. (PubMed id 8471696)9 Waldmeier P.C....Howald H. (1993)
    1031. Reversible monoamine oxidase-A inhibitors in panic disorder. (PubMed id 8313401)9 Bakish D....D'Souza J. (1993)
    1032. In vitro hepatic biotransformation of moclobemide (Ro 11-1163) in man and rat. (PubMed id 8259692)9 VallA"s B....Rahmani R. (1993)
    1033. Differential increases in catecholamine metabolizing enzymes in amyotrophic lateral sclerosis. (PubMed id 8405291)9 Ekblom J....Jossan S.S. (1993)
    1034. Brofaromine in depression: a Canadian multicenter pla cebo trial and a review of standard drug comparative studies. (PubMed id 8313397)9 Chouinard G....Kukha-Mohamad S.A. (1993)
    1035. An update of recent moclobemide interaction data. (PubMed id 8468439)9 Dingemanse J. (1993)
    1036. Synthesis and characterization of 11C-labeled fluoroc lorgyline: a monoamine oxidase A specific inhibitor for positron emission tomog raphy. (PubMed id 8293522)9 Ohmomo Y....Yokoyama A. (1993)
    1037. Estrogen modulation of catecholamine synthesis and monoamine oxidase A activity in the human neuroblastoma cell line SK-ER3. (PubMed id 7903862)9 Ma Z.Q....Maggi A. (1993)
    1038. [Brain monoamine oxidase in aging wild Norway rats, chosen for lack of aggressive behavior toward humans] (PubMed id 8511882)9 VoA-tenko N.N. (1993)
    1039. Cytotoxicity of dopamine-derived 6,7-dihydroxy-1,2,3, 4-tetrahydroisoquinolines. (PubMed id 8093579)9 Maruyama W....Naoi M. (1993)
    1040. Dopamine metabolism and neurotransmission in primate brain in relationship to monoamine oxidase A and B inhibition. (PubMed id 8390270)9 Youdim M.B. and Riederer P. (1993)
    1041. Clinical overview on moclobemide. (PubMed id 8255982)9 Tiller J.W. (1993)
    1042. Newer aspects of the reversible inhibitor of MAO-A an d serotonin reuptake, brofaromine. (PubMed id 8430214)9 Waldmeier P.C. (1993)
    1043. Safety of moclobemide in clinical use. (PubMed id 8313399)9 Chen D.T. and Ruch R. (1993)
    1044. Reversible monoamine oxidase-A inhibitors in resistant major depression. (PubMed id 1498903)9 Nolen W.A....Haffmans P.M. (1992)
    1045. The new generation of monoamine oxidase inhibitors. (PubMed id 1609114)9 Cesura A.M. and Pletscher A. (1992)
    1046. Biochemistry and pharmacology of moclobemide, a prototype RIMA. (PubMed id 1546143)9 Haefely W....Da Prada M. (1992)
    1047. Brofaromine in panic disorder: a pilot study with a new reversible inhibitor of monoamine oxidase-A. (PubMed id 1494591)9 Garcia-Borreguero D....Krieg J.C. (1992)
    1048. RIMA: a safe concept in the treatment of depression w ith moclobemide. (PubMed id 1394030)9 Amrein R....Schmid-Burgk W. (1992)
    1049. Biochemical effects of high single doses of moclobemi de in man: correlation with plasma concentrations. (PubMed id 1347659)9 Dingemanse J....GA1ntert T.W. (1992)
    1050. Safety of moclobemide taken in overdose for attempted suicide. (PubMed id 1546127)9 Hetzel W. (1992)
    1051. Deprenyl alters behavior and caudate dopamine through an amphetamine-like action. (PubMed id 1475291)9 Okuda C....Kuczenski R. (1992)
    1052. Efficacy of moclobemide in different patient groups: a meta-analysis of studies. (PubMed id 1347658)9 Angst J. and Stabl M. (1992)
    1053. New pharmacological approaches to the management of d epression: from theory to clinical practice. (PubMed id 1580888)9 Norman T.R....Burrows G.D. (1992)
    1054. An Australian multicentre study of moclobemide versus amitriptyline in the treatment of depression. (PubMed id 1417632)9 Evans L....Adena M. (1992)
    1055. Brain gamma-aminobutyrate aminotransferase (GABA-T) and monoamine oxidase (MAO) in patients with Alzheimer's disease. (PubMed id 1627256)9 Sherif F....Oreland L. (1992)
    1056. Antidepressants and cognition: comparative effects of moclobemide, viloxazine and maprotiline. (PubMed id 1546142)9 Allain H....Gandon J.M. (1992)
    1057. Monoamine oxidase inhibitors phenelzine and brofaromi ne increase plasma serotonin and decrease 5-hydroxyindoleacetic acid in patient s with major depression: relationship to clinical improvement. (PubMed id 1282522)9 Celada P....Artigas F. (1992)
    1058. Serum prolactin and luteinizing hormone levels and the activities of hypothalamic monoamine oxidase A and B and phenylethanolamine-N-methyl transferase are changed during sexual maturation in male rats treated neonatally with melatonin. (PubMed id 1287192)9 Moreno M.L....Esquifino A.I. (1992)
    1059. Hereditary Lewy-body parkinsonism and evidence for a genetic etiology of Parkinson's disease. (PubMed id 1341965)9 Duvoisin R.C. and Johnson W.G. (1992)
    1060. Influence of food on the tyramine pressor effect duri ng chronic moclobemide treatment of healthy volunteers. (PubMed id 1483487)9 Audebert C....Cano J.P. (1992)
    1061. Active control equivalence trials: some methodologica l aspects. (PubMed id 1546152)9 Ferner U. and Neumann N. (1992)
    1062. Use of moclobemide in children with attention deficit hyperactivity disorder. (PubMed id 1546129)9 Trott G.E....Nissen G. (1992)
    1063. Recent advances in antidepressant drugs. (PubMed id 1609337)9 Priest R.G....Steinert J. (1992)
    1064. Brain gamma-aminobutyrate transaminase and monoamine oxidase activities in suicide victims. (PubMed id 1790159)9 Sherif F....Oreland L. (1991)
    1065. Sudden infant death syndrome: altered aminergic-cholinergic synaptic markers in hypothalamus. (PubMed id 1719064)9 Sparks D.L. and Hunsaker J.C. (1991)
    1066. The oxidation of dopamine by the semicarbazide-sensitive amine oxidase (SSAO) from rat vas deferens. (PubMed id 2009089)9 Lizcano J.M....Unzeta M. (1991)
    1067. Cardiovascular responses to serotonin in experimental liver disease. (PubMed id 1959874)9 Jacob G....Bomzon A. (1991)
    1068. [Multicenter study comparing efficacy and tolerance o f moclobemide and fluvoxamine in hospitalized and ambulatory patients with seve re depressive episodes] (PubMed id 1904620)9 Barrelet L....Gachoud J.P. (1991)
    1069. [The role of monoamine oxidase in the regulation of m itochondrial energy functions] (PubMed id 1759390)9 Medvedev A.E. and Gorkin V.Z. (1991)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4128 HGNC: 6833 AceView: MAOA Ensembl:ENSG00000189221 euGenes: HUgn4128
    ECgene: MAOA Kegg: 4128 H-InvDB: MAOA

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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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    NameDescription
    PharmGKB entry for MAOA Pharmacogenomics, SNPs, Pathways
    GeneReviewshttp://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/MAOA
    Wikipedia http://en.wikipedia.org/wiki/Monoamine_oxidase

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