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MANEAL Gene

protein-coding   GIFtS: 45
GCID: GC01P038259

Mannosidase, Endo-Alpha-Like

  Search for MANEAL
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Mannosidase, Endo-Alpha-Like1 2
Glycoprotein Endo-Alpha-1,2-Mannosidase-Like Protein2
EC 3.2.1.-3
EC 3.2.1.1308

External Ids:    HGNC: 264521   Entrez Gene: 1491752   Ensembl: ENSG000001850907   UniProtKB: Q5VSG83   

Export aliases for MANEAL gene to outside databases

Previous GC identifers: GC01P037930 GC01P038032 GC01P036378


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for MANEAL Gene:
MANEAL (mannosidase, endo-alpha-like) is a protein-coding gene. GO annotations related to this gene include hydrolase activity. An important paralog of this gene is MANEA.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NT_032977.10  NC_018912.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the MANEAL gene promoter:
         COUP-TF1   COUP-TF   HFH-1   COUP   HNF-4alpha1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMANEAL promoter sequence
   Search Chromatin IP Primers for MANEAL

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MANEAL


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p34.3   Ensembl cytogenetic band:  1p34.3   HGNC cytogenetic band: 1p34.3

MANEAL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MANEAL gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P038259:  view genomic region     (about GC identifiers)

Start:
38,259,474 bp from pter      End:
38,267,278 bp from pter
Size:
7,805 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: MANEL_HUMAN, Q5VSG8 (See protein sequence)
Recommended Name: Glycoprotein endo-alpha-1,2-mannosidase-like protein  
Size: 457 amino acids; 51317 Da
Secondary accessions: Q6DD86 Q6P497 Q8N5P8 Q96G55 Q96N42
Alternative splicing: 3 isoforms:  Q5VSG8-1   Q5VSG8-2   Q5VSG8-3   

Explore the universe of human proteins at neXtProt for MANEAL: NX_Q5VSG8

Explore proteomics data for MANEAL at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus
  • 4 DME Specific Peptides for MANEAL (Q5VSG8)
     GSSHQNW  FIALLVEE  ITSFNEWHEGTQIE  FIPSVGPGYIDTSIRPWN 


    See MANEAL Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001026910.1  NP_001106954.1  NP_689709.1  

    ENSEMBL proteins: 
     ENSP00000362136   ENSP00000380755   ENSP00000432567   ENSP00000437312   ENSP00000328770  

    MANEAL Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Purified Protein for MANEAL
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    GenScript Custom Purified and Recombinant Proteins Services for MANEAL
    Novus Biologicals MANEAL Protein
    Novus Biologicals MANEAL Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MANEAL

    MANEAL Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Cloud-Clone Corp. Antibodies for MANEAL
    Search ThermoFisher Antibodies for MANEAL
    LSBio Antibodies in human, mouse, rat for MANEAL

    MANEAL Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for MANEAL
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for MANEAL
    Cloud-Clone Corp. CLIAs for MANEAL


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR026071 Glyco_Hydrolase_99

    Graphical View of Domain Structure for InterPro Entry Q5VSG8

    ProtoNet protein and cluster: Q5VSG8

    UniProtKB/Swiss-Prot: MANEL_HUMAN, Q5VSG8
    Similarity: Belongs to the glycosyl hydrolase 99 family


    MANEAL for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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         Enzyme Numbers (IUBMB): EC 3.2.1.1302 EC 3.2.1.-1

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016787hydrolase activity IEA--
         
    MANEAL for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for MANEAL:
     Increased G2M DNA content  Increased gamma-H2AX phosphory 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MANEAL
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MANEAL

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MANEAL
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MANEAL

    miRNA
    Products:
        
    miRTarBase miRNAs that target MANEAL:
    hsa-mir-20a-5p (MIRT050585)

    Block miRNA regulation of human, mouse, rat MANEAL using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MANEAL (see all 11):
    hsa-miR-3194-5p hsa-miR-187* hsa-miR-27a hsa-miR-202 hsa-miR-128 hsa-miR-3681* hsa-miR-211 hsa-miR-204
    SwitchGear 3'UTR luciferase reporter plasmidMANEAL 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for MANEAL
    Predesigned siRNA for gene silencing in human, mouse, rat MANEAL

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for MANEAL

    Clone
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    OriGene clones in human, mouse for MANEAL (see all 19)
    OriGene ORF clones in mouse, rat for MANEAL
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): MANEAL (NM_001113482)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MANEAL
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MANEAL

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for MANEAL
    Browse ESI BIO Cell Lines and PureStem Progenitors for MANEAL 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MANEAL


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MANEL_HUMAN, Q5VSG8: Golgi apparatus membrane; Single-pass type II membrane protein (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    golgi apparatus5

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0016021integral component of membrane IEA--

    MANEAL for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MANEAL
    Interactions:

        Search GeneGlobe Interaction Network for MANEAL

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MANEAL (MANEL)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for MANEAL gene (3 alternative transcripts): 
    NM_001031740.2  NM_001113482.1  NM_152496.2  

    Unigene Cluster for MANEAL:

    Mannosidase, endo-alpha-like
    Hs.534562  [show with all ESTs]
    Unigene Representative Sequence: NM_001113482
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000373045(uc001cby.2) ENST00000397631(uc001cbx.2) ENST00000532512
    ENST00000525897 ENST00000329006(uc001cbz.2)
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat MANEAL using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate MANEAL (see all 11):
    hsa-miR-3194-5p hsa-miR-187* hsa-miR-27a hsa-miR-202 hsa-miR-128 hsa-miR-3681* hsa-miR-211 hsa-miR-204
    SwitchGear 3'UTR luciferase reporter plasmidMANEAL 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for MANEAL
    Predesigned siRNA for gene silencing in human, mouse, rat MANEAL
    Clone
    Products:
         
    OriGene clones in human, mouse for MANEAL (see all 19)
    OriGene ORF clones in mouse, rat for MANEAL
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 3): MANEAL (NM_001113482)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MANEAL
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MANEAL
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for MANEAL
    OriGene qSTAR qPCR primer pairs in human, mouse for MANEAL
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MANEAL
      QuantiTect SYBR Green Assays in human, mouse, rat MANEAL
      QuantiFast Probe-based Assays in human, mouse, rat MANEAL

    Additional mRNA sequence: 

    AB188490.1 AK055996.1 AK301399.1 BC009952.2 BC031903.1 BC063587.1 BC077730.1 

    8 DOTS entries:

    DT.100775868  DT.91737100  DT.100015823  DT.100775870  DT.121454748  DT.121329221  DT.40273368  DT.121109708 

    5 AceView cDNA sequences:

    BC038190 BX115437 BE779767 BE218495 AW341178 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for MANEAL    About this scheme

    ExUns: 1a · 1b · 1c ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5a · 5b
    SP1:                    -                 -     -               
    SP2:                    -                                       
    SP3:                    -           -                           
    SP4:                                -                           


    ECgene alternative splicing isoforms for MANEAL

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MANEAL expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTCAGTGCTA
    MANEAL Expression
    About this image


    MANEAL expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Limb (Muscoskeletal System)
             Limb Muscle Progenitor Cells Forelimb Myotome
     
     Skeletal Muscle (Muscoskeletal System)
             Limb Muscle Progenitor Cells Forelimb Myotome
    MANEAL Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MANEAL Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.534562
        Custom PCR Arrays for MANEAL
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for MANEAL
    OriGene qSTAR qPCR primer pairs in human, mouse for MANEAL
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MANEAL
    QuantiTect SYBR Green Assays in human, mouse, rat MANEAL
    QuantiFast Probe-based Assays in human, mouse, rat MANEAL
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MANEAL

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for MANEAL gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Maneal1 , 5 mannosidase, endo-alpha-like1, 5 87.76(n)1
    93.81(a)1
      4 (57.92 cM)5
    2150901  NM_001007573.21  NP_001007574.11 
     1248552395 
    chicken
    (Gallus gallus)
    Aves MANEAL1 mannosidase, endo-alpha-like 77.23(n)
    79.85(a)
      419611  XM_417758.4  XP_417758.2 
    lizard
    (Anolis carolinensis)
    Reptilia MANEAL6
    mannosidase, endo-alpha-like
    60(a)
    1 ↔ 1
    1(179956996-179965755)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia manea1 mannosidase, endo-alpha 69.44(n)
    76.39(a)
      100124973  NM_001102908.1  NP_001096378.1 
    zebrafish
    (Danio rerio)
    Actinopterygii si:ch211-30b16.21 si:ch211-30b16.2 67.21(n)
    69.46(a)
      566679  NM_001045114.1  NP_001038579.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG140156
    --
    24(a)
    1 → many
    2L(5536850-5539196)


    ENSEMBL Gene Tree for MANEAL (if available)
    TreeFam Gene Tree for MANEAL (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MANEAL gene
    MANEA2  
    1 SIMAP similar gene for MANEAL using alignment to 3 protein entries:     MANEL_HUMAN (see all proteins):
    MANEA

    MANEAL for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for MANEAL
    PGOHUM00000240355


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MANEAL (see all 194)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 1 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1921006251,2
    --38257885(+) CTCCAA/CAAATG 2 -- us2k10--------
    rs283802451,2
    C,F,H--38258005(+) ACTTCT/GGGGAA 2 -- us2k1 tfbs310Minor allele frequency- G:0.04NS EA 1572
    rs120306901,2
    C--38258007(+) TTCTGG/CGAAAG 2 -- us2k1 tfbs3 trp33Minor allele frequency- C:0.31NA EA 242
    rs1850792931,2
    --38258139(+) TGAGAC/TGGGAA 2 -- us2k10--------
    rs1878856361,2
    C--38258300(+) TTCATA/TCACAT 2 -- us2k10--------
    rs794862681,2
    F--38258376(+) CCCTGC/ATCCTC 2 -- us2k11Minor allele frequency- A:0.01EA 120
    rs1923343451,2
    --38258386(+) CTTCCC/TGGGTT 2 -- us2k10--------
    rs1385949641,2
    C--38258632(+) CTGGTA/GCTCAC 2 -- us2k10--------
    rs125630371,2
    C,F,A,H--38258644(+) TAAACG/CGCACT 2 -- us2k127Minor allele frequency- C:0.22NS EA NA 3072
    rs1179565961,2
    F--38258798(+) TTTACG/AGGAAC 2 -- us2k11Minor allele frequency- A:0.01EA 120

    HapMap Linkage Disequilibrium report for MANEAL (38259474 - 38267278 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for MANEAL:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv871810CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MANEAL
    DNA2.0 Custom Variant and Variant Library Synthesis for MANEAL

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease from the University of Copenhagen DISEASES database for MANEAL:
    Duodenum cancer

    MANEAL for disorders           About GeneDecksing


    Export disorders for MANEAL gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MANEAL gene integrated from 10 sources:
    (articles sorted by number of sources associating them with MANEAL)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 149175 HGNC: 26452 AceView: FLJ31434.1 Ensembl:ENSG00000185090 euGenes: HUgn149175
    ECgene: MANEAL H-InvDB: MANEAL

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MANEAL Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MANEAL gene:
    Search GeneIP for patents involving MANEAL

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for MANEAL  
     OriGene qPCR primer pairs and template standards for MANEAL   OriGene Protein Over-expression Lysate for MANEAL  
     OriGene MassSpec something-or-other for MANEAL   OriGene clones in human, mouse for MANEAL  
     OriGene qSTAR qPCR primer pairs in human, mouse for MANEAL   OriGene Purified Protein for MANEAL  
     OriGene ORF clones in mouse, rat for MANEAL   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for MANEAL   OriGene Custom Protein Services for MANEAL  

     
     
     Block miRNA regulation of human, mouse, rat MANEAL using miScript Target Protectors SeqTarget long-range PCR primers for resequencing MANEAL
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MANEAL Predesigned siRNA for gene silencing in human, mouse, rat MANEAL
     QuantiFast Probe-based Assays in human, mouse, rat MANEAL QuantiTect SYBR Green Assays in human, mouse, rat MANEAL
     Custom PCR Arrays for MANEAL Search Chromatin IP Primers for MANEAL
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MANEAL  Search GeneGlobe Interaction Network for MANEAL
     Regulatory tfbs in MANEAL promoter
     GenScript Custom Purified and Recombinant Proteins Services for MANEAL GenScript cDNA clones with any tag delivered in your preferred vector for MANEAL
     GenScript Custom Assay Services for MANEAL GenScript Custom overexpressing Cell Line Services for MANEAL
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
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     Novus Tissue Slides
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     Browse ESI BIO Cell Lines and PureStem Progenitors for MANEAL
     Gene Synthesis
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     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MANEAL
     SwitchGear 3'UTR luciferase reporter plasmids for MANEAL
     SwitchGear Promoter luciferase reporter plasmids for MANEAL
     Search ThermoFisher Antibodies for MANEAL
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MANEAL
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MANEAL
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MANEAL
     LSBio Antibodies in human, mouse, rat for MANEAL
    Customized transgenic rodents for:
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