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Aliases for MANBAL Gene

Aliases for MANBAL Gene

  • Mannosidase, Beta A, Lysosomal-Like 2 3

External Ids for MANBAL Gene

Summaries for MANBAL Gene

GeneCards Summary for MANBAL Gene

MANBAL (Mannosidase, Beta A, Lysosomal-Like) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MANBAL Gene

Genomics for MANBAL Gene

Genomic Location for MANBAL Gene

Start:
37,289,638 bp from pter
End:
37,317,260 bp from pter
Size:
27,623 bases
Orientation:
Plus strand

Genomic View for MANBAL Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MANBAL Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MANBAL Gene

Regulatory Elements for MANBAL Gene

Proteins for MANBAL Gene

  • Protein details for MANBAL Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9NQG1-MANBL_HUMAN
    Recommended name:
    Protein MANBAL
    Protein Accession:
    Q9NQG1
    Secondary Accessions:
    • A8KAA6
    • E1P5V3

    Protein attributes for MANBAL Gene

    Size:
    85 amino acids
    Molecular mass:
    9467 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MANBAL Gene

Proteomics data for MANBAL Gene at MOPED

Post-translational modifications for MANBAL Gene

No Post-translational modifications

Other Protein References for MANBAL Gene

No data available for DME Specific Peptides for MANBAL Gene

Domains for MANBAL Gene

Protein Domains for MANBAL Gene

InterPro:
Blocks:
ProtoNet:

UniProtKB/Swiss-Prot:

MANBL_HUMAN
Family:
  • Belongs to the UPF0239 family.:
    • Q9NQG1
genes like me logo Genes that share domains with MANBAL: view

No data available for Gene Families for MANBAL Gene

Function for MANBAL Gene

Gene Ontology (GO) - Molecular Function for MANBAL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with MANBAL: view

Phenotypes for MANBAL Gene

GenomeRNAi human phenotypes for MANBAL:
genes like me logo Genes that share phenotypes with MANBAL: view

miRNA for MANBAL Gene

miRTarBase miRNAs that target MANBAL

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for MANBAL Gene

Localization for MANBAL Gene

Subcellular locations from UniProtKB/Swiss-Prot for MANBAL Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MANBAL Gene COMPARTMENTS Subcellular localization image for MANBAL gene
Compartment Confidence
plasma membrane 2
cytosol 1
endoplasmic reticulum 1
extracellular 1
mitochondrion 1
nucleus 1

Gene Ontology (GO) - Cellular Components for MANBAL Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with MANBAL: view

Pathways for MANBAL Gene

SuperPathways for MANBAL Gene

No Data Available

Interacting Proteins for MANBAL Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000362707%0d%0a9606.ENSP00000385269%0d%0a9606.ENSP00000365576%0d%0a
Selected Interacting proteins: ENSP00000362707 Q9NQG1-MANBL_HUMAN for MANBAL Gene via STRING UniProtKB I2D

Gene Ontology (GO) - Biological Process for MANBAL Gene

None

No data available for Pathways by source for MANBAL Gene

Transcripts for MANBAL Gene

Unigene Clusters for MANBAL Gene

Mannosidase, beta A, lysosomal-like:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MANBAL Gene

ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b · 7c · 7d · 7e
SP1: - -
SP2: -
SP3: - - - - - -
SP4: - - -
SP5: -
SP6: - - - - - - -
SP7: -

Relevant External Links for MANBAL Gene

GeneLoc Exon Structure for
MANBAL
ECgene alternative splicing isoforms for
MANBAL

Expression for MANBAL Gene

mRNA expression in normal human tissues for MANBAL Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for MANBAL Gene

SOURCE GeneReport for Unigene cluster for MANBAL Gene Hs.6126

genes like me logo Genes that share expressions with MANBAL: view

Orthologs for MANBAL Gene

This gene was present in the common ancestor of chordates.

Orthologs for MANBAL Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MANBAL 36
  • 99.22 (n)
  • 98.82 (a)
MANBAL 37
  • 99 (a)
OneToOne
cow
(Bos Taurus)
Mammalia MANBAL 36
  • 88.29 (n)
  • 93.24 (a)
MANBAL 37
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MANBAL 36
  • 89.19 (n)
  • 90.54 (a)
MANBAL 37
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Manbal 36
  • 87.84 (n)
  • 86.49 (a)
Manbal 16
Manbal 37
  • 86 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MANBAL 37
  • 74 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MANBAL 37
  • 51 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Manbal 36
  • 87.84 (n)
  • 91.89 (a)
chicken
(Gallus gallus)
Aves -- 37
  • 45 (a)
OneToMany
-- 37
  • 58 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia MANBAL 37
  • 68 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii MANBAL 37
  • 57 (a)
OneToOne
Species with no ortholog for MANBAL:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MANBAL Gene

ENSEMBL:
Gene Tree for MANBAL (if available)
TreeFam:
Gene Tree for MANBAL (if available)

Paralogs for MANBAL Gene

Pseudogenes.org Pseudogenes for MANBAL Gene

genes like me logo Genes that share paralogs with MANBAL: view

No data available for Paralogs for MANBAL Gene

Variants for MANBAL Gene

Sequence variations from dbSNP and Humsavar for MANBAL Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
rs1043404 -- 37,316,701(+) ACAGA(A/G)TCACA utr-variant-3-prime
rs1043415 -- 37,316,835(+) CTCCT(C/G)CTGAT utr-variant-3-prime
rs1043432 -- 37,316,940(+) AGCTG(C/T)GACAG utr-variant-3-prime
rs1043453 -- 37,316,993(+) AGGCC(A/G)GGGTA utr-variant-3-prime
rs1043494 -- 37,317,189(+) CAATT(C/T)TTTCA utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for MANBAL Gene

Variant ID Type Subtype PubMed ID
nsv524059 CNV Loss 19592680
nsv509767 CNV Insertion 20534489
nsv470551 CNV Gain 18288195

Relevant External Links for MANBAL Gene

HapMap Linkage Disequilibrium report
MANBAL

Disorders for MANBAL Gene

No disorders were found for MANBAL Gene.

No data available for UniProtKB/Swiss-Prot for MANBAL Gene

Publications for MANBAL Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  4. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PMID: 17207965) Lamesch P. … Vidal M. (Genomics 2007) 3
  5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3

Products for MANBAL Gene

Sources for MANBAL Gene

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