MAN2C1 Gene
protein-coding GIFtS: 56
GCID: GC15M075648
|
|
mannosidase, alpha, class 2C, member 1 (Previous symbols: MANA1, MANA)
| |
Aliases for MAN2C1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Mannosidase, Alpha, Class 2C, Member 11 2 | | MAN6A82 | | MANA1 2 3 5 | | Alpha-Mannosidase 2C12 | | MANA11 2 3 | | Mannosidase, Alpha 6A82 | | Alpha Mannosidase 6A8B2 3 | | Mannosidase, Alpha A, Cytoplasmic2 | | Alpha-D-Mannoside Mannohydrolase2 3 | | Mannosidase Alpha Class 2C Member 13 | | EC 3.2.1.243 8 | | |
Export aliases for MAN2C1 gene to outside databasesPrevious GC identifers: GC15M071525 GC15M068739 GC15M073224 GC15M073363 GC15M073435 GC15M052406 |
Summaries for MAN2C1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
summary
for MAN2C1: Mannosidases are divided into two subtypes; I and II, (EC numbers 3.2.1.113 and 3.2.1.114 respectively) which display a wide expression pattern. Mannosidase I hydrolyzes (1,2)-linked alpha-D-mannose residues in the oligo-mannose oligosaccharide Man9(GlcNAc)2 and mannosidase II hydrolyzes (1,3)- and (1,6)-linked alpha-D-mannose residues in Man5(GlcNAc)3. Both subtypes require a divalent cation cofactor. Mutations in mannosidases can cause mannosidosis (mannosidase I deficiency).
|
Genomic Views for MAN2C1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010194.17
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the MAN2C1 gene promoter: E2F-4 E2F-3a E2F-5 GATA-3 E2F-2 E2F E2F-1 HSF2 STAT3 ARP-1 Other transcription factors
Search SABiosciences Chromatin IP Primers for MAN2C1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAN2C1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q11-q13 Ensembl cytogenetic band: 15q24.2 HGNC cytogenetic band: 15q11-qterMAN2C1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15M075648: view genomic region
(about GC identifiers)
Start:
|
75,648,133 bp from pter |
End:
|
75,660,971 bp from pter |
Size:
|
12,839 bases |
Orientation:
|
minus strand |
|
Proteins for MAN2C1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: MA2C1_HUMAN, Q9NTJ4 (See
protein sequence)Recommended Name: Alpha-mannosidase 2C1 Size: 1040 amino acids; 115835 Da
Cofactor: Binds 1 zinc ion per subunit (By similarity)
Sequence caution: Sequence=AAC00190.2; Type=Frameshift; Positions=1013; Sequence=AAC00568.1; Type=Frameshift;Positions=1013;
Secondary accessions: Q13358 Q9UL64Explore the universe of human proteins at neXtProt for MAN2C1: NX_Q9NTJ4
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9NTJ4 4/5 DME Specific Peptides for MAN2C1 (Q9NTJ4) (see all 5)
MAN2C1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (4 alternative transcripts):
NP_001243423.1 NP_001243424.1 NP_001243425.1 NP_006706.2 ENSEMBL proteins: ENSP00000455998 ENSP00000457788 ENSP00000454589 ENSP00000267978 ENSP00000456914 ENSP00000390738 ENSP00000456667 ENSP00000456419 ENSP00000454406 ENSP00000456257 ENSP00000455788 ENSP00000455803 ENSP00000457833 Human Recombinant Protein Products:
MAN2C1 Antibody Products: Assay Products for MAN2C1: |
Protein
Domains / Families for MAN2C1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MAN2C1 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9NTJ4ProtoNet protein and cluster: Q9NTJ4 1 Blocks protein family: IPB000602 Glycoside hydrolase
UniProtKB/Swiss-Prot: MA2C1_HUMAN, Q9NTJ4Similarity: Belongs to the glycosyl hydrolase 38 family |
Function for MAN2C1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: MA2C1_HUMAN, Q9NTJ4Catalytic activity: Hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides Genatlas biochemistry entry for MAN2C1:alpha-mannosidase,class 2C,member 1,membrane type,cytoplasmic Enzyme Number (IUBMB): EC 3.2.1.241 2
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAN2C1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAN2C1 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: MAN2C1 (NM_006715) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MAN2C1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAN2C1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAN2C1 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004559 | alpha-mannosidase activity |
IEA | -- | | GO:0008270 | zinc ion binding |
IEA | -- | | GO:0030246 | carbohydrate binding |
IEA | -- |
MAN2C1 for ontologies About GeneDecksing
2 GenomeRNAi human phenotypes for MAN2C1:
|
Pathways & Interactions for MAN2C1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Other glycan degradation | |
Pathway sources See GeneCards unified pathways Show all pathways
1
Kegg Pathway (Kegg details for MAN2C1):
MAN2C1 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MAN2C1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 10)
 5/30 Interacting proteins for MAN2C1 (Q9NTJ42, 3 ENSP000002679784) via UniProtKB, MINT, STRING, and/or I2D (see all 30)About this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006013 | mannose metabolic process |
IEA | -- |
MAN2C1 for ontologies About GeneDecksing
|
Drugs & Compounds for MAN2C1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Compounds for MAN2C1 available from Tocris Bioscience About this table Search CenterWatch for drugs/clinical trials and news about MAN2C1 / MA2C1 
|
Transcripts for MAN2C1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for MAN2C1 gene (4 alternative transcripts): NM_001256494.1 NM_001256495.1 NM_001256496.1 NM_006715.3 Unigene Clusters for MAN2C1: Mannosidase, alpha, class 2C, member 1 Hs.26232 [show with all ESTs], Hs.598731 [show with all ESTs]Unigene Representative Sequences: BX647111, BC01008118/42 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 42): ENST00000562067 ENST00000564929 ENST00000569482 ENST00000565683(uc002bah.3) ENST00000563622(uc010bkk.3) ENST00000267978(uc002baf.3 uc002bag.3 uc010umi.1 uc010umj.1) ENST00000561693 ENST00000566099 ENST00000566569 ENST00000563528 ENST00000567163 ENST00000564570 ENST00000564785 ENST00000567360 ENST00000563441 ENST00000563368 ENST00000569176 ENST00000566013
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAN2C1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAN2C1 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: MAN2C1 (NM_006715) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MAN2C1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAN2C1  |
Additional cDNA sequence: BC010081.2 24/41 DOTS entries (see all 41): DT.100830878 DT.75103591 DT.100784834 DT.102839744 DT.100037002 DT.100772863 DT.87017892 DT.99938837 DT.95285978 DT.121052819 DT.75103192 DT.95134376 DT.102839743 DT.101984918 DT.87016070 DT.91758163 DT.100801898 DT.100801902 DT.121052738 DT.121052767 DT.40257454 DT.95294448 DT.95313666 DT.100801909 23 AceView cDNA sequences: BM542205 CD108955 BC010081 AA774591 AA236459 BF439747 AA460970 AA460369 CD251769 AW195462 AI564808 AW137397 CA444315 AI038103 AW204250 BF972814 BU660448 BX111851 AA476633 AA234078 AA461280 C75138 AA460803 GeneLoc Exon Structure
5/27 Alternative Splicing Database (ASD) splice patterns (SP) for MAN2C1 (see all 27) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | ^ | 7a | · | 7b | · | 7c | ^ | 8 | ^ | 9a | · | 9b | ^ | 10a | · | 10b | ^ | 11a | · | 11b | · | 11c | · | 11d | ^ | |
| SP1: | |   | |   | - |   | |   | |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | - |   | - |   | |   | |   | |
| SP2: | |   | |   | - |   | |   | |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | - |   | - |   | |   | |   | |
| SP3: | |   | |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | - |   | |   | |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 12 | ^ | 13a | · | 13b | ^ | 14a | · | 14b | · | 14c | ^ | 15 | ^ | 16a | · | 16b | ^ | 17a | · | 17b | · | 17c | ^ | 18a | · | 18b | ^ | 19 | ^ | 20 | ^ | 21a | · | 21b | · | 21c | ^ | 22 | ^ | 23a | · | 23b | ^ | 24a | · | 24b | · | 24c | ^ | 25a | · | |
| SP1: | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | - |   | |   | |   | |   | - |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |
| SP2: | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | - |   | |   | |   | |   | - |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 25b | · | 25c | · | 25d | ^ | 26 | ^ | 27a | · | 27b | ^ | 28a | · | 28b | · | 28c | ^ | 29 | |
| SP1: | - |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |
| SP2: | - |   | |   | - |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for MAN2C1
|
Expression for MAN2C1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MAN2C1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: AGGCCCACAA
About this image See MAN2C1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for MAN2C1
SOURCE GeneReport for Unigene clusters: Hs.26232 Hs.598731 SABiosciences Custom PCR Arrays for MAN2C1
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MAN2C1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MAN2C1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAN2C1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAN2C1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAN2C1 |
Orthologs for MAN2C1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for MAN2C1 gene from 6/24 species (see all 24) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
mouse (Mus musculus) |
Mammalia |
Man2c11 , 5 |
mannosidase, alpha, class 2C, member 11, 5 |
87.17(n)1 89.99(a)1 |
  |
9 (30.89 cM)5 737441 NM_028636.21 NP_082912.11 571306905 |
chicken (Gallus gallus) |
Aves |
MAN2C16 |
Uncharacterized protein |
70(a) |
1 ↔ 1 |
10(3507351-3518987) |
lizard (Anolis carolinensis) |
Reptilia |
MAN2C16 |
-- |
62(a) |
1 ↔ 1 |
AAWZ02040306(3769-5633) |
zebrafish (Danio rerio) |
Actinopterygii |
BM316533.12 |
-- |
75.23(n) |
  |
BM316533.1 |
baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes |
AMS1(YGL156W)4 AMS11 |
Vacuolar alpha mannosidase, involved in free oligosaccharide more4 Ams1p1 |
45.02(n)1 39.05(a)1 |
  |
7(210416-213667)4 8527211, 4 NP_011359.11, 4 |
E. coli (Escherichia coli) |
Gamma proteobacteria |
mngB6 |
alpha-mannosidase |
18(a) |
1 ↔ 1 |
Chromosome(767201-769834) |
ENSEMBL Gene Tree for MAN2C1 (if available) TreeFam Gene Tree for MAN2C1 (if available)  |
Paralogs for MAN2C1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for MAN2C1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 15 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for MAN2C1 (75648133 - 75660971 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for MAN2C1: --  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MAN2C1 |
|
Disorders
/ Diseases for MAN2C1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MAN2C1 for disorders About GeneDecksing
OMIM gene information: 154580
OMIM disorders: --
11 diseases for MAN2C1: About MalaCardspneumatosis cystoides intestinalis mannosidosis meckel's diverticulum mannosidase deficiency disease epididymitis esophageal carcinoma esophagitis pneumonia immunodeficiency carcinoma prostatitis Export disorders for MAN2C1 gene to outside databases
|
Publications for MAN2C1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MAN2C1 gene, integrated from 9 sources (see all 47): (articles sorted by number of sources associating them with MAN2C1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
- Isolation, characterization, and expression of cDNAs encoding murine alpha-mannosidase II, a Golgi enzyme that controls conversion of high mannose to complex N-glycans. (PubMed id 1757461)1, 3 Moremen K.W. and Robbins P.W. (1991)
- Assignment of cytoplasmic alpha-mannosidase (MANA) and confirmation of mitochondrial isocitrate dehydrogenase (IDHM) to the q11 leads to qter region of chromosome 15 in man. (PubMed id 752528)1, 3 Champion M.J....Shows T.B. (1978)
- Inhibition of alpha-mannosidase Man2c1 gene expression suppresses growth of esophageal carcinoma cells through mitotic arrest and apoptosis. (PubMed id 19018777)1, 9 Tian Y....Zhu L.P. (2008)
- Inhibition of the alpha-mannosidase Man2c1 gene expression enhances adhesion of Jurkat cells. (PubMed id 16721356)1, 9 Qu L....Zhu L.P. (2006)
- Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Gene expression and methylation signatures of MAN2C1 are associated with PTSD. (PubMed id 21508515)1 Uddin M....Koenen K.C. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
|
External Searches for MAN2C1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing MAN2C1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing MAN2C1 gene
(According to HUGE)
About This Section
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Specialized Databases showing MAN2C1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
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| Name | Description |
| PharmGKB entry for MAN2C1 | Pharmacogenomics, SNPs, Pathways |
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| Patent Information for MAN2C1 gene: Search GeneIP for patents involving MAN2C1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products for MAN2C1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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| | | | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MAN2C1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MAN2C1 | | OriGene Protein Over-expression Lysate for MAN2C1 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for MAN2C1 | | OriGene 3'-UTR Clone for MAN2C1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAN2C1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAN2C1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for MAN2C1 | | OriGene Custom Protein Services for MAN2C1 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MAN2C1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MAN2C1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAN2C1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MAN2C1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAN2C1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAN2C1 |
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 | | MAN2C1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAN2C1 |
|  |  |  | | | Search ThermoFisher Antibodies for MAN2C1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAN2C1 |
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