Aliases for MAN2A2 Gene
External Ids for MAN2A2 Gene
Previous GeneCards Identifiers for MAN2A2 Gene
GeneCards Summary for MAN2A2 Gene
MAN2A2 (Mannosidase Alpha Class 2A Member 2) is a Protein Coding gene. Among its related pathways are Intra-Golgi traffic and N-glycan antennae elongation in the medial/trans-Golgi. GO annotations related to this gene include carbohydrate binding and alpha-mannosidase activity. An important paralog of this gene is MAN2A1.
UniProtKB/Swiss-Prot for MAN2A2 Gene
Catalyzes the first committed step in the biosynthesis of complex N-glycans. It controls conversion of high mannose to complex N-glycans; the final hydrolytic step in the N-glycan maturation pathway.
Glycosylases are a group of enzymes that includes glucosidases, mannosidases and heparanases. There are two glucosidase subtypes, both found in the gut. They hydrolyze terminal (1,4)alpha-glucosidic linkages and (1,6)beta-glucosidic linkages, liberating alpha-glucose and beta-glucose.