MAN1A2 Gene
protein-coding GIFtS: 63
GCID: GC01P117910
|
|
mannosidase, alpha, class 1A, member 2
| |
Aliases
for MAN1A2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Mannosidase, Alpha, Class 1A, Member 21 2 | | EC 3.2.1.1133 8 | | MAN1B1 2 3 | | Alpha1,2-Mannosidase1 | | Alpha-1,2-Mannosidase IB2 3 | | Mannosyl-Oligosaccharide 1,2-Alpha-Mannosidase IB2 | | Processing Alpha-1,2-Mannosidase IB2 3 | | Mannosidase Alpha Class 1A Member 23 |
Export aliases for MAN1A2 gene to outside databasesPrevious GC identifers: GC01P118369 GC01P116748 GC01P117057 GC01P117256 GC01P117623 GC01P117711 GC01P115766 |
Summaries
for MAN1A2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for MAN1A2:
Alpha-mannosidases function at different stages of N-glycan maturation in mammalian cells. See MAN2A1 (MIM 154582) forgeneral information.(supplied by OMIM, Mar 2008)
UniProtKB/Swiss-Prot: MA1A2_HUMAN, O60476Function: Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannoseresidues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2)
 summary
for MAN1A2: Mannosidases are divided into two subtypes; I and II, (EC numbers 3.2.1.113 and 3.2.1.114 respectively)
which display a wide expression pattern. Mannosidase I hydrolyzes (1,2)-linked alpha-D-mannose residues in
the oligo-mannose oligosaccharide Man9(GlcNAc)2 and mannosidase II hydrolyzes (1,3)- and (1,6)-linked
alpha-D-mannose residues in Man5(GlcNAc)3. Both subtypes require a divalent cation cofactor. Mutations in
mannosidases can cause mannosidosis (mannosidase I deficiency).
Gene Wiki entry for MAN1A2
|
Genomic Views
for MAN1A2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_032977.9
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MAN1A2 gene promoter:
E2F-3a E2F-4 E2F-5 MEF-2 E2F-2 Evi-1 FAC1 E2F E2F-1 aMEF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for MAN1A2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAN1A2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p13 Ensembl cytogenetic band: 1p12 HGNC cytogenetic band: 1p13MAN1A2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P117910: view genomic region
(about GC identifiers)
Start:
|
117,910,071 bp from pter |
End:
|
118,071,494 bp from pter |
Size:
|
161,424 bases |
Orientation:
|
plus strand |
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Proteins
for MAN1A2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MA1A2_HUMAN, O60476 (See
protein sequence)Recommended Name: Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB Size: 641 amino acids; 73004 Da
Cofactor: Calcium
Subcellular location: Golgi apparatus membrane; Single-pass type II membrane protein
Secondary accessions: Q9H510Explore the universe of human proteins at neXtProt for MAN1A2: NX_O60476
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O60476
4/12 DME Specific Peptides for MAN1A2 (O60476) (see all 12)
MAN1A2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_006690.1
ENSEMBL proteins: ENSP00000348959 ENSP00000412706 ENSP00000396362 ENSP00000402416 Reactome Protein details: O60476
Human Recombinant Protein Products:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table
MAN1A2 for ontologies About GeneDecksing
MAN1A2 Antibody Products:
Assay Products for MAN1A2: |
Protein
Domains /
Families
for MAN1A2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MAN1A2 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry O60476ProtoNet protein and cluster: O60476 1 Blocks protein family: IPB001382 Glycosyl hydrolase family 47 signature
UniProtKB/Swiss-Prot: MA1A2_HUMAN, O60476Similarity: Belongs to the glycosyl hydrolase 47 family |
Function
for MAN1A2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MA1A2_HUMAN, O60476Function: Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannoseresidues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2)Catalytic activity: Hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in the oligo-mannoseoligosaccharide Man(9)(GlcNAc)(2)Enzyme regulation: Inhibited by both 1-deoxymannojirimycin and kifunensine Genatlas biochemistry entry for MAN1A2:alpha-mannosidase,class 1A,member 2,membrane type,expressed in brain placenta and lymphocytes,involved in processing ofAsp-linked (N) glycans
Enzyme Number (IUBMB): EC 3.2.1.1131 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAN1A2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAN1A2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: MAN1A2 (NM_006699) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MAN1A2 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAN1A2 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAN1A2 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity |
IEA | -- | | GO:0005509 | calcium ion binding |
IEA | -- |
MAN1A2 for ontologies About GeneDecksing
Animal Models:
Mouse knock-out Man1a2tm1.1Ahe for MAN1A2
5 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Man1a2):
MAN1A2 for phenotypes About GeneDecksing
|
Pathways & Interactions
for MAN1A2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Asparagine N-linked glycosylation | | | 2 | N-glycan trimming and elongation in the cis-Golgi | | | 3 | Protein processing in endoplasmic reticulum | | | 4 | N-glycan antennae elongation in the medial/trans-Golgi | | | 5 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5/6 
Reactome Pathways for MAN1A2 (see all 6)
3 
Kegg Pathways (Kegg details for MAN1A2):
UniProtKB/Swiss-Prot: MA1A2_HUMAN, O60476Pathway: Protein modification; protein glycosylation
MAN1A2 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MAN1A2
STRING Interaction
Network Preview (showing 4 interactants - click image to see more details)
5/10 Interacting proteins for MAN1A2 (O604762, 3 ENSP000003489594) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0006491 | N-glycan processing |
TAS | 9592125 | | GO:0007585 | respiratory gaseous exchange |
IEA | -- | | GO:0009100 | glycoprotein metabolic process |
-- | -- | | GO:0018279 | protein N-linked glycosylation via asparagine |
TAS | -- | | GO:0043687 | post-translational protein modification |
TAS | -- |
MAN1A2 for ontologies About GeneDecksing
|
Drugs & Compounds
for MAN1A2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
MAN1A2 for compounds About GeneDecksing
Compounds for MAN1A2 available from Tocris Bioscience About this table
3 HMDB Compounds for MAN1A2 About this table
5 Novoseek chemical compound relationships for MAN1A2 gene About this table
Search CenterWatch for drugs/clinical trials and news about MAN1A2 / MA1A2
|
Transcripts
for MAN1A2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MAN1A2 gene: NM_006699.3 Unigene Cluster for MAN1A2: Mannosidase, alpha, class 1A, member 2 Hs.435938 [show with all ESTs]Unigene Representative Sequence: BC0529545 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000356554(uc009whg.1 uc001ehd.1) ENST00000482811 ENST00000449370
ENST00000421535 ENST00000422329
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAN1A2 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAN1A2
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MAN1A2 (NM_006699) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MAN1A2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAN1A2 |
Additional cDNA sequence: AF027156.1 AK001970.1 AK090840.1 AK307842.1 BC015874.1 BC052954.1 BC063300.1 HQ234305.1 7 DOTS entries: DT.95269950 DT.86853467 DT.121406992 DT.75155982 DT.95294363 DT.40109874 DT.95175951 24/264 AceView cDNA sequences (see all 264): AA832229 AI245806 W37459 AA911882 AW951923 BM765284 BE219253 AU133800 NM_006699 AA394233 AI128620 H84925 AA235544 BQ721798 AI417585 BC063300 AI889444 AW779493 AL133955 AA478626 CR619125 AA478864 AI285106 AL119741
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for MAN1A2 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | |
| SP4: | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MAN1A2
|
Expression
for MAN1A2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MAN1A2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGCCAAGCAT
About this image
See MAN1A2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MAN1A2
SOURCE GeneReport for Unigene cluster: Hs.435938
UniProtKB/Swiss-Prot: MA1A2_HUMAN, O60476Tissue specificity: Highest levels of expression in placenta and testis
SABiosciences Expression via Pathway-Focused PCR Array including MAN1A2:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MAN1A2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MAN1A2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAN1A2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAN1A2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAN1A2 |
Orthologs
for MAN1A2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for MAN1A2 gene from 7/25 species (see all 25) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
MAN1A21 |
mannosidase, alpha, class 1A, member 2 |
80.86(n)
89.24(a) |
|
418265 XM_416490.3 XP_416490.2 |
lizard
(Anolis carolinensis) |
Reptilia |
MAN1A26 |
-- |
84(a) |
1 ↔ 1 |
GL343218.1(331057-367064) |
zebrafish
(Danio rerio) |
Actinopterygii |
Dr.187662 |
Transcribed sequence with moderate similarity to protein more |
77.26(n) |
|
BQ479592.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
alpha-Man-I1 , 3 |
N-linked glycosylation
mannosyl-oligosaccharide
more3
alpha Mannosidase I1 |
58(a)3
53.62(n)1
51.97(a)1 |
|
319571 NM_206676.21 NP_996399.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
C52E4.53
D2030.11 |
alpha 1,2, mannosidase3
Protein D2030.11 |
46(a)
(best of 2)3
54.91(n)1
47.36(a)1 |
|
V(11985739-11988071)3
1725101 NM_059715.41 NP_492116.11 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
MANIB6MNS26 |
mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS...mannosyl-oligosaccharide 1,2-alpha-mannosidase MNS... |
36(a)35(a) |
many ↔ manymany ↔ many |
1(19128144-19132318) 3(7413847-7418410) |
rice
(Oryza sativa) |
Liliopsida |
-- |
glycosyl hydrolase family 47 domain contain protei... |
37(a) |
1 → many |
4(30436035-30443247) |
ENSEMBL Gene Tree for MAN1A2 (if available)
TreeFam Gene Tree for MAN1A2 (if available) |
Paralogs
for MAN1A2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MAN1A2 gene
- MAN1C12 MAN1A12 MAN1B12
6 SIMAP similar genes for MAN1A2 using alignment to 4 protein entries: MA1A2_HUMAN (see all proteins):pp6318 MAN1C1 MAN1A1 DKFZp434I213 EDEM3 MAN1B1
MAN1A2 for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for MAN1A2
PGOHUM00000259323
|
Genomic Variants
for MAN1A2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 1 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MAN1A2 (117910071 - 118071494 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 15 variations for MAN1A2
11 CNVs: 84495 84496 84490 58327 74660 84491 74661 84494 84497 74662 74658
4 Indels: 74659 84492 74663 84493
Human Gene Mutation Database (HGMD): MAN1A2
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MAN1A2 |
|
Disorders
/ Diseases
for MAN1A2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MAN1A2 for disorders About GeneDecksing
OMIM gene information: 604345
OMIM disorders: --
4  diseases for MAN1A2: About MalaCardsmannosidosis fanconi's anemia anemia immunodeficiency
Human Genome Epidemiology (HuGE) Navigator: MAN1A2 (2 documents)
Export disorders for MAN1A2 gene to outside databases
|
Publications
for MAN1A2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MAN1A2 gene, integrated from 9 sources (see all 39):
(articles sorted by number of sources associating them with MAN1A2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning, chromosomal mapping and tissue-specific expression of a novel human alpha-1,2-mannosidase gene involved in N-glycan maturation. (PubMed id 9592125)1, 2, 3, 9 Tremblay L.O.... Herscovics A. (1998)
- The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- TLR8-dependent TNF-(alpha) overexpression in Fanconi anemia group C cells. (PubMed id 19850743)1 Vanderwerf S.M....Bagby G.C. (2009)
- Screening for replication of genome-wide SNP associations in sporadic ALS. (PubMed id 18987618)1 Cronin S....Hardiman O. (2008)
- Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
- Functional proteomics mapping of a human signaling pathway. (PubMed id 15231748)1 Colland F....Gauthier J.M. (2004)
|
External Searches for MAN1A2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MAN1A2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MAN1A2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MAN1A2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MAN1A2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MAN1A2 gene:
Search GeneIP for patents involving MAN1A2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for MAN1A2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MAN1A2 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MAN1A2 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MAN1A2 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MAN1A2 | | OriGene 3'-UTR Clone for MAN1A2 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAN1A2 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAN1A2 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for MAN1A2 | | OriGene Custom Protein Services for MAN1A2 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MAN1A2 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MAN1A2 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAN1A2 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MAN1A2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAN1A2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAN1A2 |
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 | | | MAN1A2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAN1A2 |
|  |  |  | | | | Search ThermoFisher Antibodies for MAN1A2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAN1A2 |
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