Aliases for MAN1A1 Gene
External Ids for MAN1A1 Gene
Previous GeneCards Identifiers for MAN1A1 Gene
This gene encodes a class I mammalian Golgi 1,2-mannosidase which is a type II transmembrane protein. This protein catalyzes the hydrolysis of three terminal mannose residues from peptide-bound Man(9)-GlcNAc(2) oligosaccharides and belongs to family 47 of glycosyl hydrolases. [provided by RefSeq, Jul 2012]
GeneCards Summary for MAN1A1 Gene
MAN1A1 (Mannosidase Alpha Class 1A Member 1) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Transport to the Golgi and subsequent modification. Gene Ontology (GO) annotations related to this gene include calcium ion binding and mannosidase activity. An important paralog of this gene is MAN1A2.
UniProtKB/Swiss-Prot for MAN1A1 Gene
Involved in the maturation of Asn-linked oligosaccharides. Progressively trim alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2).