Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

MAMDC4 Gene

protein-coding GIFtS: 41
GCID: GC09P139745

MAM domain containing 4

Search for MAMDC4
in

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
MAM Domain Containing 4¹ ²
AEGP¹ ² ³
MAM Domain-Containing Protein 4² ³
DKFZp434M1411¹
Apical Early Endosomal Glycoprotein²
Apical Endosomal Glycoprotein²

External Ids:	HGNC: 24083¹	Entrez Gene: 158056²	Ensembl: ENSG00000177943⁷	UniProtKB: Q6UXC1³

Export aliases for MAMDC4 gene to outside databases

Previous GC identifers: GC09P137023 GC09P138866 GC09P109206

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: AEGP_HUMAN, Q6UXC1

Function: Probably involved in the sorting and selective transport of receptors and ligands across polarized epithelia

(By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000009.11 NC_018920.1 NT_024000.16

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the MAMDC4 gene promoter:
E47 C/EBPalpha Egr-2 RORalpha1 MEF-2A AREB6 SEF-1 (1) aMEF-2 NF-Y CBF(2)
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MAMDC4 promoter sequence

Search SABiosciences Chromatin IP Primers for MAMDC4

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAMDC4

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.3 Ensembl cytogenetic band: 9q34.3 HGNC cytogenetic band: 9q34.3

MAMDC4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MAMDC4 gene location

GeneLoc information about chromosome 9 GeneLoc Exon Structure

GeneLoc location for GC09P139745: view genomic region (about GC identifiers)

Start:	139,745,395 bp from pter	End:	139,755,251 bp from pter
Size:	9,857 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: AEGP_HUMAN, Q6UXC1 (See protein sequence)

Recommended Name: Apical endosomal glycoprotein precursor

Size: 1216 amino acids; 131499 Da

Subcellular location: Membrane; Single-pass type I membrane protein (By similarity)

Secondary accessions: A2A3D4 B0QZ81 Q5T5S2 Q8NCX7

Alternative splicing: 3 isoforms: Q6UXC1-1 Q6UXC1-2 Q6UXC1-3 (May be due to intron retention. No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MAMDC4: NX_Q6UXC1

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q6UXC1

MAMDC4 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_996803.2

ENSEMBL proteins:

ENSP00000319388 ENSP00000400009 ENSP00000435513 ENSP00000411339

Human Recombinant Protein Products for MAMDC4:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein: MAMDC4 OriGene Protein Over-expression Lysate: MAMDC4 OriGene Custom Protein Services for MAMDC4
	GenScript Custom Purified and Recombinant Proteins Services for MAMDC4
	Novus Biologicals MAMDC4 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for MAMDC4

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005768	endosome	--	--
GO:0016021	integral to membrane	IEA	--

MAMDC4 for ontologies About GeneDecksing

MAMDC4 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for MAMDC4
	GenScript Custom Superior Antibodies Services for MAMDC4
	Novus Biologicals MAMDC4 Antibody
	Search for Antibodies for MAMDC4 at Abcam
	Uscn Antibodies for MAMDC4
	Search ThermoFisher Antibodies for MAMDC4

Assay Products for MAMDC4:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for MAMDC4
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for MAMDC4

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

MAMDC4 for domains About GeneDecksing

4 InterPro domains/families:

IPR023415 LDLR_class-A_CS

IPR002172 LDrepeatLR_classA_rpt

IPR000998 MAM_dom

IPR008985 ConA-like_lec_gl_sf

Graphical View of Domain Structure for InterPro Entry Q6UXC1

ProtoNet protein and cluster: Q6UXC1

1 Blocks protein family: IPB002172 Low density lipoprotein-receptor

UniProtKB/Swiss-Prot: AEGP_HUMAN, Q6UXC1

Similarity: Contains 3 LDL-receptor class A domains

Similarity: Contains 6 MAM domains

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: AEGP_HUMAN, Q6UXC1

Function: Probably involved in the sorting and selective transport of receptors and ligands across polarized epithelia

(By similarity)

Animal Models:

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for MAMDC4

miRNA Products:		OriGene 3'-UTR Clone: MAMDC4 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MAMDC4
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate MAMDC4
		SwitchGear 3'UTR luciferase reporter plasmid: MAMDC4 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MAMDC4 (see all 7) OriGene shRNA RFP: MAMDC4 OriGene siRNA: MAMDC4
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MAMDC4
		Sirion Biotech Custom design and validation of potent shRNA sequences against MAMDC4

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for MAMDC4
			Sirion Biotech Customized adenovirus for overexpression of MAMDC4 Sirion Biotech Customized adenovirus for potent knockdown of MAMDC4

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAMDC4 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAMDC4 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: MAMDC4 (NM_206920)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for MAMDC4
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAMDC4

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for MAMDC4
		Search LifeMap BioReagents cell lines for MAMDC4
		Sirion Biotech Customized stable knockdown cell line services for MAMDC4 Sirion Biotech Customized inducible knockdown cell line services for MAMDC4 Sirion Biotech Customized stable overexpressing cell line services for MAMDC4 Sirion Biotech Customized inducible overexpressing cell line services for MAMDC4

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAMDC4

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for MAMDC4

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0015031	protein transport	IEA	--

MAMDC4 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for MAMDC4
Search CenterWatch for drugs/clinical trials and news about MAMDC4 / AEGP

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for MAMDC4 gene:

NM_206920.2

Unigene Cluster for MAMDC4:

MAM domain containing 4

Hs.376780 [show with all ESTs]

Unigene Representative Sequence: AY358419

6 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000485732 ENST00000317446(uc004cjs.3) ENST00000413647 ENST00000481327

ENST00000479475 ENST00000445819(uc011mej.2)

miRNA Products:		OriGene 3'-UTR Clone: MAMDC4 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MAMDC4
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate MAMDC4
		SwitchGear 3'UTR luciferase reporter plasmid: MAMDC4 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MAMDC4 (see all 7) OriGene shRNA RFP: MAMDC4 OriGene siRNA: MAMDC4
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MAMDC4
		Sirion Biotech Custom design and validation of potent shRNA sequences against MAMDC4

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAMDC4 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAMDC4 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: MAMDC4 (NM_206920)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for MAMDC4
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAMDC4

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MAMDC4 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat MAMDC4
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAMDC4
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAMDC4

Additional cDNA sequence:

AY358419.1 BC144258.1 BC144259.1

3 DOTS entries:

DT.100739467 DT.40316134 DT.101983584

24/383 AceView cDNA sequences (see all 383):

BM832536 AA954003 AL045051 BM709330 AI139948 AF393504 AL137659 BG272982

AA687909 CA433414 BU727547 CB158840 AV693647 BU157095 BQ640096 CD671496

AI198392 BU726352 CD107634 BE502037 BU173973 BQ639651 BM662299 CR614794

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

MAMDC4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGGGCAGCCC

About this image

MAMDC4 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 2 LifeMap Cells

Name

Category

PureStem™ mesenchymal progenitor SM30 (Embryonic Progenitor Cell)

Adipose, Bone, Cartilage

PureStem™ progenitor W8 (Embryonic Progenitor Cell)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See MAMDC4 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MAMDC4

SOURCE GeneReport for Unigene cluster: Hs.376780

SABiosciences Custom PCR Arrays for MAMDC4

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MAMDC4 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat MAMDC4
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAMDC4
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAMDC4

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAMDC4

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for MAMDC4 gene from 3/13 species (see all 13) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	MAMDC4⁶	Uncharacterized protein	37(a)	1 ↔ 1	17(936761-945861)
lizard (Anolis carolinensis)	Reptilia	MAMDC4⁶	--	17(a)	1 ↔ 1	GL344740.1(720-11959)
zebrafish (Danio rerio)	Actinopterygii	LOC797166¹	apical endosomal glycoprotein-like	46.51(n) 35.76(a)		797166 XM_001337588.3 XP_001337624.3

ENSEMBL Gene Tree for MAMDC4 (if available)
TreeFam Gene Tree for MAMDC4 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for MAMDC4 gene

MDGA2² MDGA1² C10orf112² MAMDC2²

1 SIMAP similar gene for MAMDC4 using alignment to 2 protein entries: AEGP_HUMAN (see all proteins):

NRP1

MAMDC4 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 9 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs191981575^1,2		--	139746122(+)	`CCAGAC/TGGGCA`	1	--	us2k¹		0	--	--	--	--
rs142620055^1,2		--	139746254(+)	`AAAGAC/TCCTGC`	1	--	us2k¹		0	--	--	--	--
rs149861969^1,2		--	139746290(+)	`AAACCA/GAAGTT`	1	--	us2k¹		0	--	--	--	--
rs145810029^1,2		--	139746332(+)	`CGGACA/GGCACC`	1	--	us2k¹		0	--	--	--	--
rs148968561^1,2		--	139746363(+)	`ATGACA/GGCGTG`	1	--	us2k¹		0	--	--	--	--
rs184626787^1,2		--	139746415(+)	`AGAACA/GCAGGG`	1	--	us2k¹		0	--	--	--	--
rs143767717^1,2		--	139746422(+)	`AGGGAA/CCAGCT`	1	--	us2k¹		0	--	--	--	--
rs138282861^1,2		--	139746743(+)	`CACTGA/GGTGGG`	1	--	us2k¹		0	--	--	--	--
rs140884332^1,2	C	--	139746869(+)	`CAACCA/TTGCCT`	2	M L	mis¹		1		NA	4546
rs201584323^1,2		--	139746907(+)	`GTCCTC/GTTCCT`	2	L	syn¹		0	--	--	--	--

HapMap Linkage Disequilibrium report for MAMDC4 (139745395 - 139755251 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 7 variations for MAMDC4
7 CNVs: 3785 9631 30350 5415 23294 30359 31536

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MAMDC4

DNA2.0 Custom Variant and Variant Library Synthesis for MAMDC4

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for MAMDC4 gene integrated from 9 sources:
(articles sorted by number of sources associating them with MAMDC4)

Utopia: connect your pdf to the dynamic
world of online information

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)^{1, 2} Clark H.F.... Gray A.M. (2003)
Molecular characterization of an apical early endosomal glycoprotein from developing rat intestinal epithelial cells. (PubMed id 7829488)^{1, 3} Speelman B.A....Wilson J.M. (1995)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)² Sjoeblom T.... Velculescu V.E. (2006)
DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)² Humphray S.J.... Dunham I. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 158056	HGNC: 24083	AceView: PHPT1andAEGP	Ensembl:ENSG00000177943	euGenes: HUgn158056
ECgene: MAMDC4	H-InvDB: MAMDC4

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for MAMDC4	Pharmacogenomics, SNPs, Pathways

Intellectual Property for MAMDC4 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for MAMDC4 gene:
Search GeneIP for patents involving MAMDC4

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Phosphatase Activity Assays/Reagents		Browse Recombinant/Natural Proteins

	Browse OriGene Antibodies		OriGene shRNA RFP for MAMDC4
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MAMDC4		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MAMDC4
	OriGene Protein Over-expression Lysate for MAMDC4		Browse OriGene Fluorogenic Cell Assay Kits
	OriGene siRNA for MAMDC4		OriGene 3'-UTR Clone for MAMDC4
	OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAMDC4		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAMDC4
	Browse OriGene GFP tagged cDNA clones in CMV expression vector		Browse OriGene MicroRNA Expression Plasmids
	Browse OriGene basic RS shRNAs		Browse OriGene validated miRNA SYBR primer pairs
	OriGene Purified Protein for MAMDC4		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for MAMDC4		OriGene Custom Protein Services for MAMDC4
	OriGene Custom Immunoassay Development

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MAMDC4
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MAMDC4
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAMDC4
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MAMDC4
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAMDC4
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAMDC4

	GenScript Custom Purified and Recombinant Proteins Services for MAMDC4		GenScript cDNA clones with any tag delivered in your preferred vector for MAMDC4
	GenScript Custom Assay Services for MAMDC4		GenScript Custom Superior Antibodies Services for MAMDC4
	GenScript Custom overexpressing Cell Line Services for MAMDC4		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Regulatory tfbs in MAMDC4 promoter
	Search Chromatin IP Primers for MAMDC4
	RT² qPCR Primer Assay in human, mouse, rat MAMDC4
	Search GNC Networks for MAMDC4
	SABiosciences Custom PCR Arrays for MAMDC4

Search Tocris compounds for MAMDC4

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological cDNA Clones
	Antibodies/Proteins Production Services
	Rabbit Monoclonal Antibody Platform
	Bulk Purchasing

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	MAMDC4 antibodies
	MAMDC4 lysates

	Search for Antibodies for MAMDC4 at Abcam
	See all of Abcam's Antibodies, Kits and Proteins for MAMDC4
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

MAMDC4 Proteins, Antibodies, CLIAs, and ELISAs

Search LifeMap BioReagents cell lines for MAMDC4

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAMDC4

	SwitchGear 3'UTR luciferase reporter plasmids for MAMDC4
	SwitchGear Promoter luciferase reporter plasmids for MAMDC4

Search ThermoFisher Antibodies for MAMDC4

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAMDC4

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for MAMDC4

Sirion Biotech Customized:

	stable knockdown cell line services for MAMDC4
	inducible knockdown cell line services for MAMDC4
	design and validation of potent shRNA sequences against MAMDC4
	adenovirus for potent knockdown of MAMDC4
	adenovirus for overexpression of MAMDC4
	stable overexpressing cell line services for MAMDC4
	inducible overexpressing cell line services for MAMDC4

GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013 , 14 May 2013

View Random Gene

Category			VWF (GIFTS: 73) von Willebrand factor
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes MAMDC4 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4

Advanced Search

Export list of displayed genes

MAMDC4 Gene

MAM domain containing 4

Aliases
for MAMDC4 gene

Summaries
for MAMDC4 gene

Genomic Views
for MAMDC4 gene

Proteins
for MAMDC4 gene

Protein Domains /
Families
for MAMDC4 gene

Function
for MAMDC4 gene

Pathways & Interactions
for MAMDC4 gene

Drugs & Compounds
for MAMDC4 gene

Transcripts
for MAMDC4 gene

Expression
for MAMDC4 gene

Orthologs
for MAMDC4 gene

Paralogs
for MAMDC4 gene

Genomic Variants
for MAMDC4 gene

Disorders / Diseases
for MAMDC4 gene

Publications
for MAMDC4 gene

External Searches for MAMDC4 gene

Genome Databases showing MAMDC4 gene

Other Databases showing MAMDC4 gene

Specialized Databases showing MAMDC4 gene

Intellectual Property
for MAMDC4 gene

Products
for MAMDC4 gene

View Random Gene

Advanced Search

Export list of displayed genes

MAMDC4 Gene

MAM domain containing 4

Aliasesfor MAMDC4 gene

Summariesfor MAMDC4 gene

Genomic Viewsfor MAMDC4 gene

Proteinsfor MAMDC4 gene

Protein Domains /Familiesfor MAMDC4 gene

Functionfor MAMDC4 gene

Pathways & Interactionsfor MAMDC4 gene

Drugs & Compoundsfor MAMDC4 gene

Transcriptsfor MAMDC4 gene

Expression for MAMDC4 gene

Orthologsfor MAMDC4 gene

Paralogsfor MAMDC4 gene

Genomic Variantsfor MAMDC4 gene

Disorders / Diseasesfor MAMDC4 gene

Publicationsfor MAMDC4 gene

External Searches for MAMDC4 gene

Genome Databases showing MAMDC4 gene

Other Databases showing MAMDC4 gene

Specialized Databases showing MAMDC4 gene

Intellectual Propertyfor MAMDC4 gene

Productsfor MAMDC4 gene

View Random Gene

Aliases
for MAMDC4 gene

Summaries
for MAMDC4 gene

Genomic Views
for MAMDC4 gene

Proteins
for MAMDC4 gene

Protein Domains /
Families
for MAMDC4 gene

Function
for MAMDC4 gene

Pathways & Interactions
for MAMDC4 gene

Drugs & Compounds
for MAMDC4 gene

Transcripts
for MAMDC4 gene

Expression
for MAMDC4 gene

Orthologs
for MAMDC4 gene

Paralogs
for MAMDC4 gene

Genomic Variants
for MAMDC4 gene

Disorders / Diseases
for MAMDC4 gene

Publications
for MAMDC4 gene

Intellectual Property
for MAMDC4 gene

Products
for MAMDC4 gene