Aliases for MAGT1 Gene
External Ids for MAGT1 Gene
Previous GeneCards Identifiers for MAGT1 Gene
This gene encodes a magnesium cation transporter protein that localizes to the cell membrane. This protein also associates with N-oligosaccharyl transferase and therefore may have a role in N-glycosylation. Mutations in this gene cause mental retardation X-linked type 95 (MRX95). This gene may have multiple in-frame translation initiation sites, one of which would encode a shorter protein with an N-terminus containing a signal peptide at amino acids 1-29. [provided by RefSeq, Jan 2010]
GeneCards Summary for MAGT1 Gene
MAGT1 (Magnesium Transporter 1) is a Protein Coding gene. Diseases associated with MAGT1 include Immunodeficiency, X-Linked, With Magnesium Defect, Epstein-Barr Virus Infection And Neoplasia and X-Linked Magnesium Deficiency With Epstein-Barr Virus Infection And Neoplasia. Among its related pathways are Transport to the Golgi and subsequent modification and Miscellaneous transport and binding events. GO annotations related to this gene include magnesium ion transmembrane transporter activity. An important paralog of this gene is TUSC3.
UniProtKB/Swiss-Prot for MAGT1 Gene
May be involved in N-glycosylation through its association with N-oligosaccharyl transferase. May be involved in Mg(2+) transport in epithelial cells.