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Aliases & Descriptions for MAGOHB
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase) About This Section
|
| Aliases |
|---|
| FLJ10292 1, 2 | | MAGOH2 3 | | MGN2 1, 2 | | mago 2 | | magoh 2 |
| | | Descriptions |
|---|
| mago-nashi homolog 2 2 | | mago-nashi homolog B 2 | | mago-nashi homolog B (Drosophila) 2 |
|
| | Search outside databases for aliases for MAGOHB gene |
Summaries for MAGOHB(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: MGN2_HUMAN, Q96A72Function: Involved in mRNA splicing and in the nonsense-mediated decay (NMD) pathway (By similarity) |
Genomic Location for MAGOHB
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences) About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 12p13.2 Ensembl cytogenetic band: 12p13.2 HGNC cytogenetic band: 12p13.2MAGOHB Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)
 GeneLoc gene densities for chromosome 12 GeneLoc Exon Structure GeneLoc location for GC12M010652:
(about GC identifiers)
Start:
|
10,648,061 bp from pter |
End:
|
10,657,460 bp from pter |
Size:
|
9,400 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000012.10 NT_009714.16
| Proteins for MAGOHB
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: MGN2_HUMAN, Q96A72 (See
protein sequence)Recommended Name: Protein mago nashi homolog 2 Size: 148 amino acids; 17276 Da
Subunit: Interacts with RBM8A and is part of the exon junction complex (EJC) containing NCBP1, NCBP2, RNPS1, RBM8A, SRRM1, NXF1, UPF3B, UPF2 and THOC4. Remains associated with the mRNA after its export to the cytoplasm and require translation of the mRNA for removal (By similarity)
Subcellular location: Nucleus (By similarity)REFSEQ proteins: NP_060518.1
ENSEMBL proteins: ENSP00000371305 ENSP00000319240
Human Recombinant Proteins               OriGene Purified Recombinant Human Protein: MAGOHB 
1 Gene Ontology (GO) cellular component term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- | About this table
Antibodies for MAGOHB: Assays for MAGOHB: | Protein
Domains/ Families for MAGOHB(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q96A72
ProtoNet protein and cluster: Q96A72 1 Blocks protein family: IPB004023 Mago nashi protein
UniProtKB/Swiss-Prot: MGN2_HUMAN, Q96A72Similarity: Belongs to the mago nashi family | Gene Function for MAGOHB
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_018048
Applied Biosystems Silencer® siRNAs for MAGOHB
Sigma-Aldrich siRNA for MAGOHB  Sigma-Aldrich shRNA for MAGOHB  Explore Sigma-Aldrich super-pooled esiRNAs 
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_018048                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_018048                                  untagged cDNA clone in CMV expression vector: NM_018048 
Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_018048
UniProtKB/Swiss-Prot: MGN2_HUMAN, Q96A72Function: Involved in mRNA splicing and in the nonsense-mediated decay (NMD) pathway (By similarity)1 Gene Ontology (GO) molecular function term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003723 | RNA binding |
IEA | -- | About this table | Pathways & Interactions for MAGOHB
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
Gene Network CentralTM Interacting Genes and Proteins Network for MAGOHB 
5/6 Interacting proteins for MAGOHB (ENSP000003192403 Q96A722) via UniProtKB, MINT, and/or STRING (see all 6
)About this table
4 Gene Ontology (GO) biological process terms (links to tree view): About this table
|
Drugs & Compounds for MAGOHB(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
Browse Tocris compounds for MAGOHB
|
Transcripts for MAGOHB(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene, Expression Assays from Applied Biosystems) About This Section
|               OriGene 29mer shRNA kit in GFP-retroviral vector: NM_018048
Sigma-Aldrich siRNA for MAGOHB  Sigma-Aldrich shRNA for MAGOHB  Explore Sigma-Aldrich super-pooled esiRNAs 
Applied Biosystems Silencer® siRNAs: NM_018048 REFSEQ mRNAs for MAGOHB gene: NM_018048.2
Applied Biosystems TaqMan ® Gene Expression Assays: NM_018048               OriGene GFP tagged cDNA clone in CMV expression vector: NM_018048                                  Myc/DDK tagged cDNA clone in CMV expression vector: NM_018048                                  untagged cDNA clone in CMV expression vector: NM_018048  Additional cDNA sequence: AF165518.1 AK001154.1 AK022720.1 BC010905.1 CR604359.1 14 DOTS entries: DT.110126 DT.92439363 DT.92439367 DT.100680654 DT.308826 DT.91912193 DT.100788082 DT.99932203 DT.100723817 DT.120759585 DT.99936630 DT.100788085 DT.95376404 DT.95300342 24/127 AceView cDNA sequences (see all 127
):BX335457 CR604359 CA413908 BX283230 BE881038 NM_018048 AK022720 BF185893 BG531258 AW999759 BG532957 CD723604 BG533740 BU540128 BE887551 AA442090 BF207705 AK096106 BG493927 AL709293 BU933036 AW292923 BU509193 BC010905 Unigene Cluster for MAGOHB: Mago-nashi homolog B (Drosophila) Hs.104650 [show with all ESTs]Unigene Representative Sequence: NM_018048
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for MAGOHB (see all 6
)
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | · | 6c | · | 6d | ^ | 7 | ^ | 8 | |
| SP1: | |   | |   | |   | - |   | - |   | |   | |   | - |   | - |   | - |   | - |   | - |   | |   | |   | |
| SP2: | |   | |   | |   | - |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | - |   | - |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | - |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   |
About this scheme
ECgene alternative splicing isoforms for MAGOHB
2 Ensembl transcripts including schematic representations: ENST00000381881
ENST00000320756
|
Expression for MAGOHB
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| MAGOHB expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for MAGOHB
1 / 2 6 probe-sets matching MAGOHB gene Data from
(Publications) and GNF BioGPS About these images About these images
CGAP SAGE TAG: GGTTGGACAG
SOURCE GeneReport for Unigene cluster: Hs.104650 UniProtKB/Swiss-Prot: MGN2_HUMAN, Q96A72Tissue specificity: Ubiquitous |
Orthologs for MAGOHB
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for MAGOHB gene from 5/12 species (see all 12
)
About this table Species with no ortholog for MAGOHB
ENSEMBL Gene Tree for MAGOHB | Paralogs for MAGOHB(Paralogs according to 1HomoloGene and 2Ensembl, Pseudogenes according to 3Pseudogene.org) About This Section
| Paralogs for MAGOHB gene
- MAGOH2
|
SNPs/Variants for MAGOHB(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for MAGOHB (up to first 250kb)
|
Disorders & Mutations for MAGOHB
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
| -- |
Medical News for MAGOHB(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications for MAGOHB (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 10/16 PubMed articles for MAGOHB gene (see all 16
): |
Search for MAGOHB
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing MAGOHB
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing MAGOHB
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MAGOHB(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| About This Section
| --
| Services for MAGOHB(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals, Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich, Enzo Life Sciences, and/or Tocris Bioscience) About This Section
| 
 Products for MAGOHB:

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GeneCards Homepage - Last full update: 2 Jul 2009
Incremental update: 13 Oct 2009
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