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Aliases for MAGIX Gene

Aliases for MAGIX Gene

  • MAGI Family Member, X-Linked 2 3 5
  • PDZ Domain Containing, X Chromosome 3
  • JM10 3
  • PDZX 3

External Ids for MAGIX Gene

Previous GeneCards Identifiers for MAGIX Gene

  • GC0XP048907
  • GC0XP049019
  • GC0XP046676

Summaries for MAGIX Gene

GeneCards Summary for MAGIX Gene

MAGIX (MAGI Family Member, X-Linked) is a Protein Coding gene. An important paralog of this gene is MAGI2.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MAGIX Gene

Genomics for MAGIX Gene

Regulatory Elements for MAGIX Gene

Promoters for MAGIX Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MAGIX on UCSC Golden Path with GeneCards custom track

Genomic Location for MAGIX Gene

49,162,564 bp from pter
49,168,483 bp from pter
5,920 bases
Plus strand

Genomic View for MAGIX Gene

Genes around MAGIX on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MAGIX Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MAGIX Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MAGIX Gene

Proteins for MAGIX Gene

  • Protein details for MAGIX Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    PDZ domain-containing protein MAGIX
    Protein Accession:
    Secondary Accessions:
    • A6XND4
    • A8MSX9
    • B7WP26
    • Q14C81

    Protein attributes for MAGIX Gene

    334 amino acids
    Molecular mass:
    35217 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for MAGIX Gene

    Alternative splice isoforms for MAGIX Gene


neXtProt entry for MAGIX Gene

Proteomics data for MAGIX Gene at MOPED

Post-translational modifications for MAGIX Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for MAGIX Gene

Domains & Families for MAGIX Gene

Gene Families for MAGIX Gene

Protein Domains for MAGIX Gene


Suggested Antigen Peptide Sequences for MAGIX Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 PDZ (DHR) domain.
  • Contains 1 PDZ (DHR) domain.
genes like me logo Genes that share domains with MAGIX: view

Function for MAGIX Gene

genes like me logo Genes that share phenotypes with MAGIX: view

Animal Model Products

miRNA for MAGIX Gene

miRTarBase miRNAs that target MAGIX

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MAGIX Gene

Localization for MAGIX Gene

Subcellular locations from

Jensen Localization Image for MAGIX Gene COMPARTMENTS Subcellular localization image for MAGIX gene
Compartment Confidence
cytosol 3
nucleus 3
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MAGIX Gene

Pathways & Interactions for MAGIX Gene

SuperPathways for MAGIX Gene

No Data Available

Interacting Proteins for MAGIX Gene

Gene Ontology (GO) - Biological Process for MAGIX Gene


No data available for Pathways by source and SIGNOR curated interactions for MAGIX Gene

Drugs & Compounds for MAGIX Gene

No Compound Related Data Available

Transcripts for MAGIX Gene

Unigene Clusters for MAGIX Gene

MAGI family member, X-linked:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MAGIX Gene

No ASD Table

Relevant External Links for MAGIX Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MAGIX Gene

mRNA expression in normal human tissues for MAGIX Gene

mRNA differential expression in normal tissues according to GTEx for MAGIX Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (x4.2) and Brain - Cerebellum (x4.2).

Protein differential expression in normal tissues from HIPED for MAGIX Gene

This gene is overexpressed in Adipocyte (49.0), Skin (13.5), and Salivary gland (6.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for MAGIX Gene

SOURCE GeneReport for Unigene cluster for MAGIX Gene Hs.193170

genes like me logo Genes that share expression patterns with MAGIX: view

Protein tissue co-expression partners for MAGIX Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for MAGIX Gene

Orthologs for MAGIX Gene

This gene was present in the common ancestor of mammals.

Orthologs for MAGIX Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MAGIX 35
  • 79.42 (n)
  • 70.78 (a)
(Canis familiaris)
Mammalia MAGIX 35
  • 76.56 (n)
  • 72.16 (a)
(Mus musculus)
Mammalia Magix 35
  • 73.23 (n)
  • 66.56 (a)
Magix 16
(Pan troglodytes)
Mammalia MAGIX 35
  • 99.33 (n)
  • 99.6 (a)
(Rattus norvegicus)
Mammalia Magix 35
  • 71.53 (n)
  • 65.22 (a)
Species with no ortholog for MAGIX:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MAGIX Gene

Gene Tree for MAGIX (if available)
Gene Tree for MAGIX (if available)

Paralogs for MAGIX Gene

Paralogs for MAGIX Gene

(4) SIMAP similar genes for MAGIX Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with MAGIX: view

Variants for MAGIX Gene

Sequence variations from dbSNP and Humsavar for MAGIX Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs5906744 -, - 49,164,918(+) GGCAC(A/G)TAGTG intron-variant, reference, missense
rs5905720 - 49,165,199(+) GGGAC(C/G)TCGTG reference, missense
rs4824462 - 49,166,361(+) CGCAG(C/T)TCGCT reference, missense
rs2091957 -- 49,164,344(+) GAGGG(A/C)GTGCT intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs4824744 -- 49,163,796(+) CCCTC(A/C)CCGCT upstream-variant-2KB, reference, synonymous-codon, utr-variant-5-prime

Structural Variations from Database of Genomic Variants (DGV) for MAGIX Gene

Variant ID Type Subtype PubMed ID
esv32909 CNV Gain+Loss 17666407
nsv528292 CNV Gain 19592680
nsv7442 OTHER Inversion 18451855
esv2555036 OTHER Inversion 19546169
dgv62n47 OTHER Inversion 21111241
esv994583 OTHER Inversion 20482838
esv1091998 OTHER Inversion 17803354
dgv63n50 OTHER Inversion 21212237
nsv435993 OTHER Inversion 17901297
nsv436719 OTHER Inversion 17901297
nsv205 OTHER Inversion 15895083

Variation tolerance for MAGIX Gene

Residual Variation Intolerance Score: 85.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 3.03; 50.19% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MAGIX Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MAGIX Gene

Disorders for MAGIX Gene

Relevant External Links for MAGIX

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MAGIX Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MAGIX Gene

Publications for MAGIX Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for MAGIX Gene

Sources for MAGIX Gene

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