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Aliases for MAGIX Gene

Aliases for MAGIX Gene

  • MAGI Family Member, X-Linked 2 3
  • PDZ Domain Containing, X Chromosome 3
  • PDZ Domain-Containing Protein MAGIX 3
  • JM10 3
  • PDZX 3

External Ids for MAGIX Gene

Previous GeneCards Identifiers for MAGIX Gene

  • GC0XP048907
  • GC0XP049019
  • GC0XP046676

Summaries for MAGIX Gene

GeneCards Summary for MAGIX Gene

MAGIX (MAGI Family Member, X-Linked) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MAGIX Gene

Genomics for MAGIX Gene

Regulatory Elements for MAGIX Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for MAGIX Gene

Start:
49,162,564 bp from pter
End:
49,183,497 bp from pter
Size:
20,934 bases
Orientation:
Plus strand

Genomic View for MAGIX Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MAGIX Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MAGIX Gene

Proteins for MAGIX Gene

  • Protein details for MAGIX Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H6Y5-MAGIX_HUMAN
    Recommended name:
    PDZ domain-containing protein MAGIX
    Protein Accession:
    Q9H6Y5
    Secondary Accessions:
    • A6XND4
    • A8MSX9
    • B7WP26
    • Q14C81

    Protein attributes for MAGIX Gene

    Size:
    334 amino acids
    Molecular mass:
    35217 Da
    Quaternary structure:
    No Data Available

    Three dimensional structures from OCA and Proteopedia for MAGIX Gene

    Alternative splice isoforms for MAGIX Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MAGIX Gene

Proteomics data for MAGIX Gene at MOPED

Post-translational modifications for MAGIX Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for MAGIX Gene

Domains for MAGIX Gene

Protein Domains for MAGIX Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for MAGIX Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9H6Y5

UniProtKB/Swiss-Prot:

MAGIX_HUMAN :
  • Q9H6Y5
Domain:
  • Contains 1 PDZ (DHR) domain.
genes like me logo Genes that share domains with MAGIX: view

No data available for Gene Families for MAGIX Gene

Function for MAGIX Gene

Gene Ontology (GO) - Molecular Function for MAGIX Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
genes like me logo Genes that share ontologies with MAGIX: view

Phenotypes for MAGIX Gene

GenomeRNAi human phenotypes for MAGIX:
genes like me logo Genes that share phenotypes with MAGIX: view

Animal Model Products

CRISPR Products

miRNA for MAGIX Gene

miRTarBase miRNAs that target MAGIX

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for MAGIX Gene

Localization for MAGIX Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MAGIX Gene COMPARTMENTS Subcellular localization image for MAGIX gene
Compartment Confidence
cytosol 3
nucleus 3
mitochondrion 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MAGIX Gene

Pathways for MAGIX Gene

SuperPathways for MAGIX Gene

No Data Available

Interacting Proteins for MAGIX Gene

Gene Ontology (GO) - Biological Process for MAGIX Gene

None

No data available for Pathways by source for MAGIX Gene

Transcripts for MAGIX Gene

Unigene Clusters for MAGIX Gene

MAGI family member, X-linked:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MAGIX

Primer Products

  • OriGene qSTAR qPCR primer pairs in human,mouse,rat for MAGIX

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MAGIX Gene

No ASD Table

Relevant External Links for MAGIX Gene

GeneLoc Exon Structure for
MAGIX
ECgene alternative splicing isoforms for
MAGIX

Expression for MAGIX Gene

mRNA expression in normal human tissues for MAGIX Gene

mRNA differential expression in normal tissues according to GTEx for MAGIX Gene

This gene is overexpressed in Brain - Cerebellar Hemisphere (4.2) and Brain - Cerebellum (4.2).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for MAGIX Gene

SOURCE GeneReport for Unigene cluster for MAGIX Gene Hs.193170

genes like me logo Genes that share expressions with MAGIX: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for MAGIX Gene

Orthologs for MAGIX Gene

This gene was present in the common ancestor of mammals.

Orthologs for MAGIX Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MAGIX 35
  • 99.33 (n)
  • 99.6 (a)
cow
(Bos Taurus)
Mammalia MAGIX 35
  • 79.42 (n)
  • 70.78 (a)
dog
(Canis familiaris)
Mammalia MAGIX 35
  • 76.56 (n)
  • 72.16 (a)
mouse
(Mus musculus)
Mammalia Magix 35
  • 73.23 (n)
  • 66.56 (a)
Magix 16
rat
(Rattus norvegicus)
Mammalia Magix 35
  • 71.53 (n)
  • 65.22 (a)
Species with no ortholog for MAGIX:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MAGIX Gene

ENSEMBL:
Gene Tree for MAGIX (if available)
TreeFam:
Gene Tree for MAGIX (if available)

Paralogs for MAGIX Gene

Selected SIMAP similar genes for MAGIX Gene using alignment to 6 proteins:

genes like me logo Genes that share paralogs with MAGIX: view

No data available for Paralogs for MAGIX Gene

Variants for MAGIX Gene

Sequence variations from dbSNP and Humsavar for MAGIX Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs2091957 -- 49,164,344(+) GAGGG(A/C)GTGCT intron-variant, utr-variant-5-prime
rs4824462 - 49,166,361(+) CGCAG(C/T)TCGCT reference, missense, nc-transcript-variant
rs5905720 - 49,165,199(+) GGGAC(C/G)TCGTG reference, missense, nc-transcript-variant
rs5906744 -, - 49,164,918(+) GGCAC(A/G)TAGTG intron-variant, missense, reference, nc-transcript-variant
rs5906745 -- 49,167,913(+) ATTTC(G/T)CAGAG utr-variant-3-prime, downstream-variant-500B, nc-transcript-variant

Structural Variations from Database of Genomic Variants (DGV) for MAGIX Gene

Variant ID Type Subtype PubMed ID
esv32909 CNV Gain+Loss 17666407
nsv528292 CNV Gain 19592680
nsv7442 OTHER Inversion 18451855
esv2555036 OTHER Inversion 19546169
dgv62n47 OTHER Inversion 21111241
esv994583 OTHER Inversion 20482838
esv1091998 OTHER Inversion 17803354
dgv63n50 OTHER Inversion 21212237
nsv435993 OTHER Inversion 17901297
nsv436719 OTHER Inversion 17901297
nsv205 OTHER Inversion 15895083

Relevant External Links for MAGIX Gene

HapMap Linkage Disequilibrium report
MAGIX

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MAGIX Gene

Disorders for MAGIX Gene

No disorders were found for MAGIX Gene.

No data available for UniProtKB/Swiss-Prot for MAGIX Gene

Publications for MAGIX Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 4
  4. An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome. (PMID: 24275569) Bian Y. … Zou H. (J. Proteomics 2014) 4
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for MAGIX Gene

Sources for MAGIX Gene

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