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Aliases for MAGEH1 Gene

Aliases for MAGEH1 Gene

  • MAGE Family Member H1 2 3 5
  • Apoptosis-Related Protein 1 3 4
  • Melanoma Antigen Family H1 2 3
  • Restin 3 4
  • APR-1 3 4
  • APR1 3 4
  • Melanoma Antigen Family H, 1 3
  • MAGE-H1 Antigen 4
  • MAGEH 3

External Ids for MAGEH1 Gene

Previous GeneCards Identifiers for MAGEH1 Gene

  • GC0XP052453
  • GC0XP053416
  • GC0XP054083
  • GC0XP054445
  • GC0XP055361
  • GC0XP055495
  • GC0XP052527

Summaries for MAGEH1 Gene

Entrez Gene Summary for MAGEH1 Gene

  • This gene belongs to the non-CT (non cancer/testis) subgroup of the melanoma-associated antigen (MAGE) superfamily. The encoded protein is likely associated with apoptosis, cell cycle arrest, growth inhibition or cell differentiation. The protein may be involved in the atRA (all-trans retinoic acid) signaling through the STAT1-alpha (signal transducer and activator of transcription 1-alpha) pathway. [provided by RefSeq, Aug 2013]

GeneCards Summary for MAGEH1 Gene

MAGEH1 (MAGE Family Member H1) is a Protein Coding gene. Among its related pathways are p75(NTR)-mediated signaling.

Gene Wiki entry for MAGEH1 Gene

No data available for UniProtKB/Swiss-Prot , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MAGEH1 Gene

Genomics for MAGEH1 Gene

Regulatory Elements for MAGEH1 Gene

Enhancers for MAGEH1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MAGEH1 on UCSC Golden Path with GeneCards custom track

Promoters for MAGEH1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around MAGEH1 on UCSC Golden Path with GeneCards custom track

Genomic Location for MAGEH1 Gene

55,452,089 bp from pter
55,453,568 bp from pter
1,480 bases
Plus strand

Genomic View for MAGEH1 Gene

Genes around MAGEH1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MAGEH1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MAGEH1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MAGEH1 Gene

Proteins for MAGEH1 Gene

  • Protein details for MAGEH1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Melanoma-associated antigen H1
    Protein Accession:
    Secondary Accessions:
    • B2R8V9
    • Q5JRJ3
    • Q9Y5M2

    Protein attributes for MAGEH1 Gene

    219 amino acids
    Molecular mass:
    24441 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MAGEH1 Gene

Proteomics data for MAGEH1 Gene at MOPED

Post-translational modifications for MAGEH1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MAGEH1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MAGEH1 Gene

Domains & Families for MAGEH1 Gene

Gene Families for MAGEH1 Gene

Protein Domains for MAGEH1 Gene


Suggested Antigen Peptide Sequences for MAGEH1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 MAGE domain.
  • Contains 1 MAGE domain.
genes like me logo Genes that share domains with MAGEH1: view

Function for MAGEH1 Gene

genes like me logo Genes that share phenotypes with MAGEH1: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MAGEH1 Gene

Localization for MAGEH1 Gene

Subcellular locations from

Jensen Localization Image for MAGEH1 Gene COMPARTMENTS Subcellular localization image for MAGEH1 gene
Compartment Confidence
nucleus 3
cytosol 2
plasma membrane 2
mitochondrion 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MAGEH1 Gene

Pathways & Interactions for MAGEH1 Gene

SuperPathways for MAGEH1 Gene

Superpath Contained pathways
1 p75(NTR)-mediated signaling
genes like me logo Genes that share pathways with MAGEH1: view

Pathways by source for MAGEH1 Gene

1 BioSystems pathway for MAGEH1 Gene

Gene Ontology (GO) - Biological Process for MAGEH1 Gene


No data available for SIGNOR curated interactions for MAGEH1 Gene

Drugs & Compounds for MAGEH1 Gene

No Compound Related Data Available

Transcripts for MAGEH1 Gene

mRNA/cDNA for MAGEH1 Gene

(1) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(166) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MAGEH1 Gene

Melanoma antigen family H, 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MAGEH1 Gene

No ASD Table

Relevant External Links for MAGEH1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MAGEH1 Gene

mRNA expression in normal human tissues for MAGEH1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for MAGEH1 Gene

This gene is overexpressed in Fetal Brain (52.3) and Islet of Langerhans (16.7).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for MAGEH1 Gene

SOURCE GeneReport for Unigene cluster for MAGEH1 Gene Hs.279819

genes like me logo Genes that share expression patterns with MAGEH1: view

Protein tissue co-expression partners for MAGEH1 Gene

- Elite partner

Primer Products

No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for MAGEH1 Gene

Orthologs for MAGEH1 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MAGEH1 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MAGEH1 35
  • 88.22 (n)
  • 93.43 (a)
  • 94 (a)
(Canis familiaris)
Mammalia MAGEH1 35
  • 87.41 (n)
  • 93.37 (a)
  • 94 (a)
(Mus musculus)
Mammalia Mageh1 35
  • 88.55 (n)
  • 92.82 (a)
Mageh1 16
Mageh1 36
  • 90 (a)
(Rattus norvegicus)
Mammalia Mageh1 35
  • 88.21 (n)
  • 92.31 (a)
(Pan troglodytes)
Mammalia MAGEH1 36
  • 100 (a)
Species with no ortholog for MAGEH1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MAGEH1 Gene

Gene Tree for MAGEH1 (if available)
Gene Tree for MAGEH1 (if available)

Paralogs for MAGEH1 Gene

genes like me logo Genes that share paralogs with MAGEH1: view

No data available for Paralogs for MAGEH1 Gene

Variants for MAGEH1 Gene

Structural Variations from Database of Genomic Variants (DGV) for MAGEH1 Gene

Variant ID Type Subtype PubMed ID
nsv435891 CNV Deletion 17901297
esv2740175 CNV Deletion 23290073
nsv469510 CNV Complex 16826518
nsv7448 OTHER Inversion 18451855

Variation tolerance for MAGEH1 Gene

Residual Variation Intolerance Score: 13.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.18; 4.12% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Relevant External Links for MAGEH1 Gene

Disorders for MAGEH1 Gene

Relevant External Links for MAGEH1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MAGEH1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MAGEH1 Gene

Publications for MAGEH1 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 67
  2. The p75 neurotrophin receptor interacts with multiple MAGE proteins. (PMID: 12414813) Tcherpakov M. … Fainzilber M. (J. Biol. Chem. 2002) 2 3
  3. Genome-wide association study of smoking behaviours among Bangladeshi adults. (PMID: 24665060) Argos M. … Ahsan H. (J. Med. Genet. 2014) 3
  4. Neonatal detection of Turner syndrome by real-time PCR gene quantification of the ARSE and MAGEH1 genes. (PMID: 25366798) CorrA-a S.C. … Longui C.A. (Genet. Mol. Res. 2014) 3
  5. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3

Products for MAGEH1 Gene

Sources for MAGEH1 Gene