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MAGEE1 Gene

protein-coding   GIFtS: 50
GCID: GC0XP075564

Melanoma Antigen Family E, 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Melanoma Antigen Family E, 11 2     MAGE-E1 Antigen2 3
DAMAGE2 3 5     KIAA15873 5
Alpha-Dystrobrevin-Associated MAGE Protein2 3     Dystrobrevin-Associated MAGE Protein2
Hepatocellular Carcinoma-Associated Protein 12 3     Hepatocellular Carcinoma-Associated HCA12
HCA12 3     Melanoma-Associated Antigen E12

External Ids:    HGNC: 249341   Entrez Gene: 576922   Ensembl: ENSG000001989347   OMIM: 3007595   UniProtKB: Q9HCI53   

Export aliases for MAGEE1 gene to outside databases

Previous GC identifers: GC0XM135820 GC0XM138147 GC0XM139216 GC0XM139976 GC0XP074516 GC0XP075430 GC0XP069280


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for MAGEE1 Gene:
This gene encodes an alpha-dystrobrevin-associated MAGE (melanoma-associated antigen) protein, which is a member
of the MAGE family. The protein contains a nuclear localization signal in the N-terminus, 30 12-amino acid
repeats beginning at nt 60 with the consensus sequence ASEGPSTSVLPT, and two MAGE domains in the C-terminus. It
may play a signaling role in brain, muscle, and peripheral nerve. This gene is located on X chromosome in a
region containing loci linked to mental retardation. (provided by RefSeq, Mar 2010)

GeneCards Summary for MAGEE1 Gene:
MAGEE1 (melanoma antigen family E, 1) is a protein-coding gene. Diseases associated with MAGEE1 include decubitus ulcer, and breast and colorectal cancer. An important paralog of this gene is MAGEH1.

UniProtKB/Swiss-Prot: MAGE1_HUMAN, Q9HCI5
Function: May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases.
Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate
complex




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000023.11  NC_018934.2  NT_011651.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the MAGEE1 gene promoter:
         E2F-4   E2F-3a   E2F-5   SREBP-1c   E2F-2   SREBP-1b   C/EBPalpha   SREBP-1a   E2F-1   E2F   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMAGEE1 promoter sequence
   Search Chromatin IP Primers for MAGEE1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MAGEE1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq13.3   Ensembl cytogenetic band:  Xq13.3   HGNC cytogenetic band: Xq13

MAGEE1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MAGEE1 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP075564:  view genomic region     (about GC identifiers)

Start:
75,648,046 bp from pter      End:
75,651,746 bp from pter
Size:
3,701 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: MAGE1_HUMAN, Q9HCI5 (See protein sequence)
Recommended Name: Melanoma-associated antigen E1  
Size: 957 amino acids; 103254 Da
Subunit: Interacts with DTNA (By similarity). Interacts with TRIM28
Sequence caution: Sequence=BAB13413.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
1 PDB 3D structure from and Proteopedia for MAGEE1:
2H5T (3D)    
Secondary accessions: Q86TG0 Q8TD92 Q9H216

Explore the universe of human proteins at neXtProt for MAGEE1: NX_Q9HCI5

Explore proteomics data for MAGEE1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys734
  • Modification sites at PhosphoSitePlus

  • See MAGEE1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_065983.1  
    ENSEMBL proteins: 
     ENSP00000354912  

    MAGEE1 Human Recombinant Protein Products:

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    Cloud-Clone Corp. CLIAs for MAGEE1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR002190 MAGE

    Graphical View of Domain Structure for InterPro Entry Q9HCI5

    ProtoNet protein and cluster: Q9HCI5

    1 Blocks protein domain: IPB002190 MAGE protein

    UniProtKB/Swiss-Prot: MAGE1_HUMAN, Q9HCI5
    Similarity: Contains 2 MAGE domains


    MAGEE1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MAGE1_HUMAN, Q9HCI5
    Function: May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases.
    Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate
    complex

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    MAGEE1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MAGEE1
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    miRNA
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    4 qRT-PCR Assays for microRNAs that regulate MAGEE1:
    hsa-miR-498 hsa-miR-1323 hsa-miR-545 hsa-miR-548o
    SwitchGear 3'UTR luciferase reporter plasmidMAGEE1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat MAGEE1

    Gene Editing
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    Sino Biological Human cDNA Clone for MAGEE1
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAGEE1

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAGEE1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    MAGE1_HUMAN, Q9HCI5: Cytoplasm, perinuclear region (By similarity). Nucleus (By similarity). Cell membrane (By
    similarity). Note=In the skeletal muscle, found at the postsynaptic membrane and is associated with a subset of
    myonuclei. May reside within nuclei and/or in perinuclear compartments. In peripheral nerves, colocalizes with
    DTNA in the Schwann cell membrane (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus4
    plasma membrane4
    cytosol2
    mitochondrion1

    Gene Ontology (GO): Selected cellular component terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ISS14623885
    GO:0005886plasma membrane ISS14623885
    GO:0016010colocalizes with dystrophin-associated glycoprotein complex ISS14623885
    GO:0030425dendrite ISS14623885
    GO:0045211postsynaptic membrane ISS14623885

    MAGEE1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MAGEE1
    Interactions:

        Search GeneGlobe Interaction Network for MAGEE1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 21)

    Selected Interacting proteins for MAGEE1 (Q9HCI51, 3 ENSP000003549124) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    USP7Q930093, ENSP000003435354I2D: score=2 STRING: ENSP00000343535
    TRIM28Q132631, ENSP000002530244EBI-949966,EBI-78139 STRING: ENSP00000253024
    CAV3ENSP000003419404STRING: ENSP00000341940
    DAG1ENSP000003124354STRING: ENSP00000312435
    DMDENSP000003549234STRING: ENSP00000354923
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008150biological_process ND--

    MAGEE1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MAGEE1 (MAGE1)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for MAGEE1 gene: 
    NM_020932.2  

    Unigene Cluster for MAGEE1:

    Melanoma antigen family E, 1
    Hs.8453  [show with all ESTs]
    Unigene Representative Sequence: NM_020932
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000361470(uc004ecm.2)
    miRNA
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    4 qRT-PCR Assays for microRNAs that regulate MAGEE1:
    hsa-miR-498 hsa-miR-1323 hsa-miR-545 hsa-miR-548o
    SwitchGear 3'UTR luciferase reporter plasmidMAGEE1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for MAGEE1
    Predesigned siRNA for gene silencing in human, mouse, rat MAGEE1
    Clone
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    GenScript: all cDNA clones in your preferred vector: MAGEE1 (NM_020932)
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    Primer
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    OriGene qPCR primer pairs and template standards for MAGEE1
    OriGene qSTAR qPCR primer pairs in human, mouse for MAGEE1
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MAGEE1
      QuantiTect SYBR Green Assays in human, mouse, rat MAGEE1
      QuantiFast Probe-based Assays in human, mouse, rat MAGEE1

    Additional mRNA sequence: 

    AB046807.1 AF086039.1 AF320909.1 AF490507.1 AK291270.1 BC050588.1 

    2 DOTS entries:

    DT.410580  DT.121323942 

    Selected AceView cDNA sequences (see all 28):

    N22111 AB046807 AI298393 AF086039 AF490507 NM_020932 AF320909 AI124583 
    BX107699 BC050588 BQ717147 T41267 BP362794 AA449441 N66646 CD630472 
    AI912696 CD512856 AA448930 AA189100 AI281387 T40424 BF952436 W28145 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MAGEE1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATTGGGGGG
    MAGEE1 Expression
    About this image

    MAGEE1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MAGEE1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.8453
        Custom PCR Arrays for MAGEE1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAGEE1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for MAGEE1 gene from Selected species (see all 4)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Magee11 , 5 melanoma antigen, family E, 11, 5 74.23(n)1
    65.64(a)1
      X (46.84 cM)5
    1075281  NM_053201.31  NP_444431.31 
     1051203785 


    ENSEMBL Gene Tree for MAGEE1 (if available)
    TreeFam Gene Tree for MAGEE1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MAGEE1 gene
    MAGEH12  MAGEE22  MAGEC32  
    Selected SIMAP similar genes for MAGEE1 using alignment to 3 protein entries:     MAGE1_HUMAN (see all proteins) (see all similar genes):
    MAGEC1    MAGEH1    MAGE-B1    MAGEA11    MAGEB16    MAGEB17
    MAGEC3    MAGEF1    MAGEC4    MAGEB4    MAGEB5    NDNL2
    MAGEC2    MAGEA10    MAGEA13P    MAGEB10    MAGEB18    MAGEB1

    MAGEE1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for MAGEE1
    PGOHUM00000241337


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MAGEE1 (see all 118)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0365864
    A breast cancer sample4--see VAR_0365862 T N mis40--------
    VAR_0365854
    A breast cancer sample4--see VAR_0365852 Y F mis40--------
    rs1882250831,2
    --75654497(+) AAGAAA/CAGGAA 1 -- us2k10--------
    rs1925083451,2
    --75654692(+) TATACC/TTAGGT 1 -- us2k10--------
    rs66479951,2
    C,F,A,H--75654848(+) CAATAA/GAGGGT 1 -- us2k121Minor allele frequency- G:0.68NS EA NA 2042
    rs1843628801,2
    --75655052(+) AAATAC/TCTACC 1 -- us2k10--------
    rs1878885591,2
    --75655099(+) CTTTTC/TTGCAT 1 -- us2k10--------
    rs1923885611,2
    --75655244(+) ATAGAA/TGACCA 1 -- us2k10--------
    rs1843519141,2
    --75655316(+) ATAGAA/GCAAAA 1 -- us2k10--------
    rs66479961,2
    C--75655541(+) CAGGCA/TTTCAG 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for MAGEE1 (75648046 - 75651746 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for MAGEE1: --
    Locus Specific Mutation Databases (LSDB): MAGEE1

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MAGEE1
    DNA2.0 Custom Variant and Variant Library Synthesis for MAGEE1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300759    OMIM disorders: --

    7 diseases for MAGEE1:    
    About MalaCards
    decubitus ulcer    breast and colorectal cancer    hepatocellular carcinoma    melanoma
    mental retardation    ataxia    colorectal cancer


    MAGEE1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): MAGEE1
    Human Genome Epidemiology (HuGE) Navigator: MAGEE1 (1 document)

    Export disorders for MAGEE1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MAGEE1 gene, integrated from 10 sources (see all 14):
    (articles sorted by number of sources associating them with MAGEE1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Frequent MAGE mutations in human melanoma. (PubMed id 20862285)1, 4 Caballero O.L....Simpson A.J. (PLoS ONE 2010)
    2. MAGE-RING protein complexes comprise a family of E3 ubiquitin ligases. (PubMed id 20864041)1, 2 Doyle J.M.... Potts P.R. (Mol. Cell 2010)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. DAMAGE, a novel alpha-dystrobrevin-associated MAGE protein in dystrophin complexes. (PubMed id 14623885)1, 3 Albrecht D.E. and Froehner S.C. (J. Biol. Chem. 2004)
    5. Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10997877)1, 2 Nagase T.... Ohara O. (DNA Res. 2000)
    6. Naturally occurring HCA1 missense mutations result in loss of function: potential impact on lipid deposition. (PubMed id 23268337)1 Doyle J.R....Kopin A.S. (J. Lipid Res. 2013)
    7. The global gene-expression profiles of U-937 human macrophages treated with Tat peptide and Tat-FITC conjugate. (PubMed id 22632162)1 Lin C.W....Jan M.S. (J Drug Target 2012)
    8. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    9. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
    10. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (Science 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57692 HGNC: 24934 AceView: MAGEE1 Ensembl:ENSG00000198934 euGenes: HUgn57692
    ECgene: MAGEE1 H-InvDB: MAGEE1

    (According to HUGE)
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    HUGE: KIAA1587

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MAGEE1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for MAGEE1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MAGEE1 gene:
    Search GeneIP for patents involving MAGEE1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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