Aliases for MAGED4B Gene
External Ids for MAGED4B Gene
This gene is a member of the MAGED gene family. It is expressed only in brain and ovary, and some transcript variants of this gene are specifically expressed in glioma cells. This gene is clustered with other MAGED genes on chromosome Xp11. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2011]
GeneCards Summary for MAGED4B Gene
MAGED4B (Melanoma Antigen Family D4B) is a Protein Coding gene. Diseases associated with MAGED4B include malignant glioma and oral squamous cell carcinoma. An important paralog of this gene is MAGED1.
UniProtKB/Swiss-Prot for MAGED4B Gene
May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.