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MAGED4B Gene

protein-coding   GIFtS: 45
GCID: GC0XM051805

Melanoma Antigen Family D, 4B

  See MAGED4B-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Melanoma Antigen Family D, 4B1 2     KIAA18593
MAGE-D4 Antigen2 3     MAGED4A3
MAGE-E1 Antigen2 3     MAGEE13
Melanoma-Associated Antigen D42     

External Ids:    HGNC: 228801   Entrez Gene: 815572   Ensembl: ENSG000001872437   OMIM: 3007655   UniProtKB: Q96JG83   

Export aliases for MAGED4B gene to outside databases

Previous GC identifers: GC0XU900705 GC0XM051822 GC0XM049240


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for MAGED4B Gene:
This gene is a member of the MAGED gene family. It is expressed only in brain and ovary, and some transcript
variants of this gene are specifically expressed in glioma cells. This gene is clustered with other MAGED genes
on chromosome Xp11. Alternatively spliced transcript variants encoding different isoforms have been described for
this gene. (provided by RefSeq, May 2011)

GeneCards Summary for MAGED4B Gene:
MAGED4B (melanoma antigen family D, 4B) is a protein-coding gene. Diseases associated with MAGED4B include malignant glioma, and oral squamous cell carcinoma. An important paralog of this gene is MAGEC2.

UniProtKB/Swiss-Prot: MAGD4_HUMAN, Q96JG8
Function: May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases.
Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate
complex

Gene Wiki entry for MAGED4B Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the MAGED4B gene promoter:
         RFX1   STAT5A   HNF-4alpha1   Meis-1b   NF-AT4   NF-AT3   IRF-7A   Meis-1a   ZID   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMAGED4B promoter sequence
   Search Chromatin IP Primers for MAGED4B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MAGED4B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp11   Ensembl cytogenetic band:  Xp11.22   HGNC cytogenetic band: Xp11

MAGED4B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MAGED4B gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM051805:  view genomic region     (about GC identifiers)

Start:
51,804,923 bp from pter      End:
51,812,368 bp from pter
Size:
7,446 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: MAGD4_HUMAN, Q96JG8 (See protein sequence)
Recommended Name: Melanoma-associated antigen D4  
Size: 741 amino acids; 81378 Da
Subunit: Interacts with TRIM27
Sequence caution: Sequence=AAH01207.1; Type=Erroneous initiation; Sequence=AAL50032.1; Type=Frameshift;
Positions=186, 219; Sequence=BAB47488.2; Type=Erroneous initiation;
Secondary accessions: A8K093 Q5HYN6 Q8WXW4 Q9BQ84 Q9BVH1 Q9BYH3 Q9BYH4 Q9H217
Alternative splicing: 4 isoforms:  Q96JG8-1   Q96JG8-2   Q96JG8-3   Q96JG8-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MAGED4B: NX_Q96JG8

Explore proteomics data for MAGED4B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See MAGED4B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (4 alternative transcripts): 
    NP_001229291.1  NP_110428.2  NP_803879.1  NP_803881.1  

    ENSEMBL proteins: 
     ENSP00000422913   ENSP00000423848   ENSP00000353252   ENSP00000421861   ENSP00000335385  
     ENSP00000422633   ENSP00000423971   ENSP00000395962  

    MAGED4B Human Recombinant Protein Products:

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    Novus Biologicals MAGED4B Protein
    Novus Biologicals MAGED4B Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MAGED4B

     
    Search eBioscience for Proteins for MAGED4B 

     
    antibodies-online proteins for MAGED4B (2 products) 

     
    antibodies-online peptides for MAGED4B

    MAGED4B Antibody Products:

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    antibodies-online antibodies for MAGED4B (2 products) 

    MAGED4B Assay Products:

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    Cloud-Clone Corp. CLIAs for MAGED4B
    Search eBioscience for ELISAs for MAGED4B 
    antibodies-online kits for MAGED4B (2 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR002190 MAGE

    Graphical View of Domain Structure for InterPro Entry Q96JG8

    ProtoNet protein and cluster: Q96JG8

    1 Blocks protein domain: IPB002190 MAGE protein

    UniProtKB/Swiss-Prot: MAGD4_HUMAN, Q96JG8
    Similarity: Contains 1 MAGE domain


    Find genes that share domains with MAGED4B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MAGD4_HUMAN, Q96JG8
    Function: May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases.
    Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate
    complex

    Animal Models:

       genOway: Develop your customized and physiologically relevant rodent model for MAGED4B

    miRNA
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    miRTarBase miRNAs that target MAGED4B:
    hsa-mir-335-5p (MIRT017566)

    Block miRNA regulation of human, mouse, rat MAGED4B using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate MAGED4B:
    hsa-miR-411* hsa-miR-141 hsa-miR-379* hsa-miR-891b hsa-miR-200a hsa-miR-450b-5p
    SwitchGear 3'UTR luciferase reporter plasmidMAGED4B 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat MAGED4B

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    Browse Sino Biological Human cDNA Clones
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAGED4B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2
    mitochondrion1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MAGED4B
    Interactions:

        Search GeneGlobe Interaction Network for MAGED4B

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    Selected Interacting proteins for MAGED4B (Q96JG82, 3 ENSP000003353854) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MAPK8IP2Q133872, 3MINT-8262521 I2D: score=2 
    CHMP243863, ENSP000003503864I2D: score=1 STRING: ENSP00000350386
    PHYHIPQ925613, ENSP000003200174I2D: score=4 STRING: ENSP00000320017
    RAE1P784063I2D: score=1 
    UBCP0CG483I2D: score=1 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MAGED4B (MAGD4)

    1 Novoseek inferred chemical compound relationship for MAGED4B gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    5-aza-2'deoxycytidine 46.8 1 15256472 (1)



    Find genes that share compounds with MAGED4B           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for MAGED4B gene (4 alternative transcripts): 
    NM_001242362.1  NM_030801.3  NM_177535.2  NM_177537.2  

    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000490581 ENST00000481096 ENST00000470594 ENST00000497164 ENST00000360134
    ENST00000485287 ENST00000335504 ENST00000471617 ENST00000481193 ENST00000514560
    ENST00000486469 ENST00000486010 ENST00000431659(uc004dpr.4 uc004dpv.4 uc004dpu.4 uc004dpt.4 uc004dps.4)

    miRNA
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    6 qRT-PCR Assays for microRNAs that regulate MAGED4B:
    hsa-miR-411* hsa-miR-141 hsa-miR-379* hsa-miR-891b hsa-miR-200a hsa-miR-450b-5p
    SwitchGear 3'UTR luciferase reporter plasmidMAGED4B 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat MAGED4B
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    GenScript: all cDNA clones in your preferred vector (see all 3): MAGED4B (NM_177535)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAGED4B
    Primer
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    OriGene qPCR primer pairs and template standards for MAGED4B
    OriGene qSTAR qPCR primer pairs in human, mouse for MAGED4B
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      QuantiTect SYBR Green Assays in human, mouse, rat MAGED4B
      QuantiFast Probe-based Assays in human, mouse, rat MAGED4B

    Selected AceView cDNA sequences (see all 191):

    BC081566 AB058762 AB040529 AW136268 AF320908 AI741489 AW068986 AL136582 
    BI118050 AK098830 AA232504 AI091646 BU517266 AI246702 BM997485 BX431256 
    BX460037 BV174918 AI082447 BQ021351 AI142536 BM998073 BX279726 BI822544 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MAGED4B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTTGGGTAT
    MAGED4B Expression
    About this image

    MAGED4B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MAGED4B Protein Expression

    UniProtKB/Swiss-Prot: MAGD4_HUMAN, Q96JG8
    Tissue specificity: Expressed only in brain and ovary among normal tissues. Isoform 1 and isoform 2 are
    specifically expressed in glioma cells among cancer cells. Detected in some renal cell carcinoma samples

        Custom PCR Arrays for MAGED4B
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAGED4B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for MAGED4B gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    dog
    (Canis familiaris)
    Mammalia LOC4809261 melanoma-associated antigen D4-like 90.23(n)
    89.86(a)
      480926  XM_005641366.1  XP_005641423.1 
    chicken
    (Gallus gallus)
    Aves MAGE6
    Gallus gallus necdin-like 2 (NDNL2), mRNA.
    40(a)
    1 → many
    JH376257.1(2550-4829)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    37(a)
    1 → many
    1(205667349-205679701)
    zebrafish
    (Danio rerio)
    Actinopterygii ndnl26
    necdin-like 2
    36(a)
    1 → many
    23(13012414-13025121) ENSDARG00000058212


    ENSEMBL Gene Tree for MAGED4B (if available)
    TreeFam Gene Tree for MAGED4B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MAGED4B gene
    MAGED41 2  MAGEC22  MAGEA9B2  MAGEB52  MAGEB162  MAGEB12  MAGEB42  MAGEC12  
    MAGEA82  MAGED22  MAGEA122  MAGEA92  MAGEB172  MAGEB102  MAGEA62  MAGED12  
    MAGEA22  MAGEA32  MAGEB22  NDN2  MAGEB32  MAGEA42  MAGEA12  MAGEA102  
    MAGEB182  MAGEA2B2  MAGEB62  MAGEL22  TRO2  MAGEA112  NDNL22  MAGEF12  
    Selected SIMAP similar genes for MAGED4B using alignment to 4 protein entries:     MAGD4_HUMAN (see all proteins) (see all similar genes):
    MAGED4    MAGEH1    TRO    MAGEA8    MAGEB2    MAGEA3
    MAGEA12    MAGEA6    MAGEF1    MAGED2    MAGEB3    MAGEC4
    NDNL2    MAGEB4    MAGEA4    MAGEA1    MAGEA9    MAGEA9B

    Find genes that share paralogs with MAGED4B           About GenesLikeMe


    1 Pseudogenes.org Pseudogene for MAGED4B
    PGOHUM00000250070


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    5 SNPs for MAGED4B    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs2000115541,2
    --51811074(+) CGAAGA/GCCTGG 16 G syn10--------
    rs2016532311,2
    --51941396(+) CCAGGC/TCTTCG 8 G syn10--------
    rs2009210011,2
    --51943949(+) CCCACA/GTAGAA 4 -- int10--------
    rs2003668011,2
    --51946397(+) GGGAGA/CGCCTC 4 -- int10--------
    rs3683638301,2
    ----51947357(+) GCAGCA/GATCTT 4 -- ut310--------

    HapMap Linkage Disequilibrium report for MAGED4B (51804923 - 51812368 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for MAGED4B:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv516643CNV Gain19592680

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing MAGED4B
    DNA2.0 Custom Variant and Variant Library Synthesis for MAGED4B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300765    OMIM disorders: --

    2 diseases for MAGED4B:    
    About MalaCards
    malignant glioma    oral squamous cell carcinoma


    Find genes that share disorders with MAGED4B           About GenesLikeMe

    10 Novoseek inferred disease relationships for MAGED4B gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    melanoma 72.3 33 11756773 (5), 15223957 (5), 15946236 (2), 7750125 (1) (see all 18)
    metastatic melanoma 48 1 9185691 (1)
    glioblastoma 47.2 2 15256472 (1), 8509230 (1)
    astrocytoma 42.2 1 12494904 (1)
    malignant glioma 36 1 15256472 (1)
    glioma 35.5 3 9154761 (2), 15256472 (1)
    metastasis 26.8 2 15305155 (1), 9650552 (1)
    tumors 24.3 23 16225959 (4), 9154761 (1), 8524854 (1), 9176405 (1) (see all 6)
    brain tumors 19.7 2 9154761 (1)
    cancer 5.16 3 12494904 (1), 16225959 (1), 17803450 (1)


    Export disorders for MAGED4B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MAGED4B gene, integrated from 10 sources (see all 52):
    (articles sorted by number of sources associating them with MAGED4B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Structural characterization and chromosomal localization of the MAGE- E1 gene. (PubMed id 11602350)1, 2, 9 Kawano Y....Ikenaka K. (Gene 2001)
    2. MAGE-RING protein complexes comprise a family of E3 ubiquitin ligases. (PubMed id 20864041)1, 2 Doyle J.M.... Potts P.R. (Mol. Cell 2010)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones. (PubMed id 12168954)1, 2 Nakajima D.... Nagase T. (DNA Res. 2002)
    6. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
    7. Prediction of the coding sequences of unidentified human genes. XX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 11347906)1, 2 Nagase T.... Ohara O. (DNA Res. 2001)
    8. MAGE-E1, a new member of the melanoma-associated antigen gene family and its expression in human glioma. (PubMed id 11406556)1, 2 Sasaki M.... Ikenaka K. (Cancer Res. 2001)
    9. Expression of MAGE-D4, a novel MAGE family antigen, is correlated with tumor-cell proliferation of non-small cell lung cancer. (PubMed id 16225959)1, 9 Ito S....Tanaka F. (Lung Cancer 2006)
    10. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 81557 HGNC: 22880 AceView: MAGED4 Ensembl:ENSG00000187243 euGenes: HUgn81557
    ECgene: MAGED4B H-InvDB: MAGED4B

    (According to HUGE)
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    HUGE: KIAA1859

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MAGED4B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MAGED4B gene:
    Search GeneIP for patents involving MAGED4B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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