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MAGED2 Gene

protein-coding   GIFtS: 58
GCID: GC0XP054834

Melanoma Antigen Family D, 2

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Melanoma Antigen Family D, 21 2     MAGE-D2 Antigen2 3
Melanoma-Associated Antigen D21 2     Breast Cancer Associated Gene 11
Breast Cancer-Associated Gene 1 Protein2 3     Hepatocellular Carcinoma Associated Protein1
Hepatocellular Carcinoma-Associated Protein JCL-12 3     Hepatocellular Carcinoma-Associated Protein HCA101
11B62 3     HCA102
BCG-12 3     MAGE-D22
BCG12 3     MAGED5

External Ids:    HGNC: 163531   Entrez Gene: 109162   Ensembl: ENSG000001023167   OMIM: 3004705   UniProtKB: Q9UNF13   

Export aliases for MAGED2 gene to outside databases

Previous GC identifers: GC0XP051686 GC0XP052772 GC0XP053439 GC0XP053800 GC0XP054717 GC0XP054850 GC0XP051883


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for MAGED2 Gene:
This gene is a member of the MAGED gene family. The MAGED genes are clustered on chromosome Xp11. This gene is
located in Xp11.2, a hot spot for X-linked mental retardation (XLMR). This gene may also be involved in several
types of cancer, including breast cancer and melanoma. Alternative splicing results in multiple transcript
variants. (provided by RefSeq, Aug 2013)

GeneCards Summary for MAGED2 Gene:
MAGED2 (melanoma antigen family D, 2) is a protein-coding gene. Diseases associated with MAGED2 include melanoma, and hepatocellular carcinoma. An important paralog of this gene is MAGEC2.

Gene Wiki entry for MAGED2 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000023.11  NC_018934.2  NT_011630.15  
Regulatory elements:
   Regulatory transcription factor binding sites in the MAGED2 gene promoter:
         p53   CUTL1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): MAGED2 promoter sequence
   Search Chromatin IP Primers for MAGED2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MAGED2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp11.2   Ensembl cytogenetic band:  Xp11.21   HGNC cytogenetic band: Xp11.2

MAGED2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MAGED2 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP054834:  view genomic region     (about GC identifiers)

Start:
54,834,032 bp from pter      End:
54,842,445 bp from pter
Size:
8,414 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: MAGD2_HUMAN, Q9UNF1 (See protein sequence)
Recommended Name: Melanoma-associated antigen D2  
Size: 606 amino acids; 64954 Da
Secondary accessions: A6NMX0 O76058 Q5BJF3 Q8NAL6 Q9H218 Q9P0U9 Q9UM52
Alternative splicing: 2 isoforms:  Q9UNF1-1   Q9UNF1-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MAGED2: NX_Q9UNF1

Explore proteomics data for MAGED2 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys207, Lys288, Lys330, Lys397, Lys469, Lys484, Lys494, Lys528
  • Glycosylation2 at Ser52
  • Modification sites at PhosphoSitePlus

  • See MAGED2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_055414.2  NP_803182.1  NP_957516.1  

    ENSEMBL proteins: 
     ENSP00000364209   ENSP00000336962   ENSP00000364198   ENSP00000364200   ENSP00000364193  
     ENSP00000364202   ENSP00000218439   ENSP00000379526  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR028810 MAGED2
     IPR002190 MAGE

    Graphical View of Domain Structure for InterPro Entry Q9UNF1

    ProtoNet protein and cluster: Q9UNF1

    1 Blocks protein domain: IPB002190 MAGE protein

    UniProtKB/Swiss-Prot: MAGD2_HUMAN, Q9UNF1
    Similarity: Contains 1 MAGE domain


    MAGED2 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Phenotypes:
         1 GenomeRNAi human phenotype for MAGED2:
     Decreased nuclei size in G2M 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MAGED2
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MAGED2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MAGED2

    miRNA
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    miRTarBase miRNAs that target MAGED2:
    hsa-mir-335-5p (MIRT017771), hsa-mir-877-3p (MIRT037133)

    Block miRNA regulation of human, mouse, rat MAGED2 using miScript Target Protectors
    5 qRT-PCR Assays for microRNAs that regulate MAGED2:
    hsa-miR-647 hsa-miR-3121-3p hsa-miR-548u hsa-miR-604 hsa-miR-3605-5p
    SwitchGear 3'UTR luciferase reporter plasmidMAGED2 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat MAGED2

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    GenScript: all cDNA clones in your preferred vector (see all 3): MAGED2 (NM_201222)
    Sino Biological Human cDNA Clone for MAGED2
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAGED2

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAGED2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus3

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MAGED2
    Interactions:

        GeneGlobe Interaction Network for MAGED2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

    Selected Interacting proteins for MAGED2 (Q9UNF12, 3 ENSP000002184394) via UniProtKB, MINT, STRING, and/or I2D (see all 597)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EEF1A1P681042, 3MINT-7945693 I2D: score=3 
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    TCEA2Q155603, ENSP000003435154I2D: score=1 STRING: ENSP00000343515
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    MEPCEQ7L2J03, ENSP000003085464I2D: score=1 STRING: ENSP00000308546
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MAGED2 (MAGD2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for MAGED2 gene (3 alternative transcripts): 
    NM_014599.5  NM_177433.2  NM_201222.2  

    Unigene Cluster for MAGED2:

    Melanoma antigen family D, 2
    Hs.522665  [show with all ESTs]
    Unigene Representative Sequence: AK092463
    13 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000375068(uc004dtk.1) ENST00000347546(uc004dto.1) ENST00000463787
    ENST00000375058(uc004dtl.1) ENST00000375060(uc004dtm.1) ENST00000485483
    ENST00000497484 ENST00000487482 ENST00000487463 ENST00000375053 ENST00000375062
    ENST00000218439 ENST00000396224(uc004dtn.1)
    miRNA
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    5 qRT-PCR Assays for microRNAs that regulate MAGED2:
    hsa-miR-647 hsa-miR-3121-3p hsa-miR-548u hsa-miR-604 hsa-miR-3605-5p
    SwitchGear 3'UTR luciferase reporter plasmidMAGED2 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for MAGED2
    Predesigned siRNA for gene silencing in human, mouse, rat MAGED2
    Clone
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    OriGene ORF clones in mouse, rat for MAGED2
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    GenScript: all cDNA clones in your preferred vector (see all 3): MAGED2 (NM_201222)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MAGED2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAGED2
    Primer
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    OriGene qPCR primer pairs and template standards for MAGED2
    OriGene qSTAR qPCR primer pairs in human, mouse for MAGED2
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat MAGED2
      QuantiTect SYBR Green Assays in human, mouse, rat MAGED2
      QuantiFast Probe-based Assays in human, mouse, rat MAGED2

    Additional mRNA sequence: 

    AF126181.1 AF128527.1 AF128528.1 AF148815.1 AF320907.1 AJ293618.1 AK092463.1 AK098645.1 
    AK297910.1 AK301599.1 AK301821.1 BC000304.2 BC091503.1 BC107040.1 BX647995.1 U92544.1 

    Selected DOTS entries (see all 30):

    DT.450043  DT.100042116  DT.92044994  DT.92464652  DT.87079441  DT.92464648  DT.100681955  DT.100848601 
    DT.100681934  DT.40288367  DT.95186940  DT.87079444  DT.95186927  DT.100875514  DT.99983002  DT.100042128 
    DT.100681933  DT.100867368  DT.100681946  DT.102835893  DT.121321810  DT.121632604  DT.95186923  DT.100033072 

    Selected AceView cDNA sequences (see all 1068):

    BG577275 BG420998 CR606543 BC000304 H13755 BG766208 BU675825 BU183361 
    CR597524 AA643888 W73618 AF320907 BM694525 BQ896869 BG766187 CA412306 
    CA943720 BM980129 BU162946 BU732294 CR605686 H13703 CA414641 CA748612 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for MAGED2 (see all 15)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7a · 7b · 7c · 7d · 7e ^ 8a · 8b · 8c · 8d ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b ^
    SP1:                                      -                       -     -     -                                   -     -                             -         
    SP2:                    -     -     -     -                                                                                                           -         
    SP3:                                      -                                                                                                           -         
    SP4:                                                                                                                                                  -         
    SP5:                    -     -     -     -           -     -     -     -     -     -                                                                           

    ExUns: 13 ^ 14a · 14b · 14c ^ 15 ^ 16 ^ 17 ^ 18a · 18b
    SP1:              -     -                                 
    SP2:              -     -                                 
    SP3:              -     -                                 
    SP4:              -     -                                 
    SP5:                                                      


    ECgene alternative splicing isoforms for MAGED2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MAGED2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATGGAAATC
    MAGED2 Expression
    About this image


    MAGED2 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 19) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Ovary (Reproductive System)    fully expand to see all 2 entries
             Ovarian Mesenchymal Stroma Cells Ovary Interstitium
             Oviduct
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Liver (Hepatobiliary System)
             Hepatocytes Liver Lobule
    MAGED2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MAGED2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.522665

    UniProtKB/Swiss-Prot: MAGD2_HUMAN, Q9UNF1
    Tissue specificity: Widely expressed in normal tissues

        Custom PCR Arrays for MAGED2
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    QuantiFast Probe-based Assays in human, mouse, rat MAGED2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAGED2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for MAGED2 gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Maged21 , 5 melanoma antigen, family D, 21, 5 88.23(n)1
    87.46(a)1
      X (68.46 cM)5
    808841  NM_030700.21  NP_109625.11 
     1508063705 
    chicken
    (Gallus gallus)
    Aves MAGE6
    Gallus gallus necdin-like 2 (NDNL2), mRNA.
    43(a)
    1 → many
    JH376257.1(2550-4829)
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    41(a)
    1 → many
    1(205667349-205679701)
    zebrafish
    (Danio rerio)
    Actinopterygii ndnl26
    necdin-like 2
    40(a)
    1 → many
    23(13012414-13025121) ENSDARG00000058212


    ENSEMBL Gene Tree for MAGED2 (if available)
    TreeFam Gene Tree for MAGED2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MAGED2 gene
    MAGEC22  MAGEA9B2  MAGEB52  MAGEB162  MAGEB12  MAGEB42  MAGEC12  MAGED42  
    MAGEA82  MAGEA122  MAGEA92  MAGEB172  MAGEB102  MAGEA62  MAGED12  MAGEA22  
    MAGEA32  MAGEB22  NDN2  MAGEB32  MAGED4B2  MAGEA42  MAGEA12  MAGEA102  
    MAGEB182  MAGEA2B2  MAGEB62  MAGEL22  TRO2  MAGEA112  NDNL22  MAGEF12  
    Selected SIMAP similar genes for MAGED2 using alignment to 3 protein entries:     MAGD2_HUMAN (see all proteins) (see all similar genes):
    MAGED1    TRO    MAGEH1    MAGEC1    MAGEC4    NDNL2
    MAGEA10    MAGEA1    MAGEC3    MAGEA8    MAGEA9    MAGEA9B
    MAGEB5    MAGEA11    MAGED4    MAGED4B    MAGEF1    MAGEA2

    MAGED2 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MAGED2 (see all 191)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0365844
    A breast cancer sample4--see VAR_0365842 K Q mis40--------
    rs1842358761,2
    --54846708(+) GACACC/TCCCCT 1 -- us2k10--------
    rs1882898921,2
    --54846811(+) TGCCAC/TCACTC 1 -- us2k10--------
    rs70609601,2
    C--54846890(+) gacaaC/Gaccta 1 -- us2k10--------
    rs46125171,2
    C,H--54846963(+) cctagA/Cattct 1 -- us2k16Minor allele frequency- C:0.00NS EA NA 422
    rs1922307621,2
    --54847059(+) GGGTGC/GGGAAT 1 -- us2k10--------
    rs1838547841,2
    C--54847102(+) CTATGG/TCTAGT 1 -- us2k10--------
    rs1112793551,2
    C,F--54847608(+) TTAGTC/TTGCAC 2 -- us2k11Minor allele frequency- T:0.00CSA 1
    rs1126892231,2
    C,F--54847664(+) GAATCT/CGTATA 2 -- us2k11Minor allele frequency- C:0.00CSA 1
    rs1381478871,2
    C--54847745(+) AACGGA/GGTTTG 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for MAGED2 (54834032 - 54842445 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for MAGED2:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2740175CNV Deletion23290073
    nsv435891CNV Deletion17901297

    Locus Specific Mutation Databases (LSDB): MAGED2

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300470    OMIM disorders: --

    14 diseases for MAGED2:    
    About MalaCards
    melanoma    hepatocellular carcinoma    breast cancer    brain cancer
    mental retardation    breast and colorectal cancer    tonsillitis    hepatitis b
    hepatitis    colorectal cancer    thyroiditis    cerebritis
    endotheliitis    prostatitis


    MAGED2 for disorders           About GeneDecksing

    Genetic Association Database (GAD): MAGED2
    Human Genome Epidemiology (HuGE) Navigator: MAGED2 (3 documents)

    Export disorders for MAGED2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MAGED2 gene, integrated from 10 sources (see all 52):
    (articles sorted by number of sources associating them with MAGED2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Use of expression data and the CGEMS genome-wide breast cancer association study to identify genes that may modify risk in BRCA1/2 mutation carriers. (PubMed id 18095154)1, 4 Walker L.C....Spurdle A.B. (Breast Cancer Res. Treat. 2008)
    2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    3. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (Nature 2005)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Expression pattern and further characterization of human MAGED2 and identification of rodent orthologues. (PubMed id 11856887)1, 2 Langnaese K.... Wieacker P. (Cytogenet. Cell Genet. 2001)
    7. Isolation of genes overexpressed in freshly isolated breast cancer specimens. (PubMed id 10752678)1, 2 Kurt R.A.... Schoof D.D. (Breast Cancer Res. Treat. 2000)
    8. A new MAGE gene with ubiquitous expression does not code for known MAGE antigens recognized by T cells. (PubMed id 10463614)1, 2 Lucas S.... Boon T. (Cancer Res. 1999)
    9. Identification of a novel MAGE D2 antisense RNA transcript in human tissues. (PubMed id 15465002)1, 9 Harper R....Wu R. (Biochem. Biophys. Res. Commun. 2004)
    10. Comparative expression analysis of the MAGED genes during embryogenesis and brain development. (PubMed id 15162511)1, 9 Bertrand M....De Backer O. (Dev. Dyn. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 10916 HGNC: 16353 AceView: MAGED2 Ensembl:ENSG00000102316 euGenes: HUgn10916
    ECgene: MAGED2 H-InvDB: MAGED2

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for MAGED2 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for MAGED2 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MAGED2 gene:
    Search GeneIP for patents involving MAGED2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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