V3 here soon-try beta now


Gene Search (GeneCards Home)	\|	GeneCards Guide	\|	User Feedback	\|	Terms of Use	\|	Notice about third-party sites

MAGED1 Gene

protein-coding GIFtS: 66

GC0XP051562

melanoma antigen family D, 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
DLXIN-1 ^¹, ²
NRAGE ^¹, ², ³
OTTHUMP00000023302 ^²
OTTHUMP00000023303 ^²
OTTHUMP00000023304 ^²
OTTHUMP00000023305 ^²

Descriptions
MAGE tumor antigen CCF ^³
MAGE-D1 antigen ^³
Neurotrophin receptor-interacting MAGE homolog ^², ³
melanoma antigen family D, 1 ^²

External Ids
HGNC: 6813¹
Entrez Gene: 9500²
UniProtKB: Q9Y5V3³
Ensembl: ENSG00000179222⁷

Search outside databases for aliases for MAGED1 gene

Previous GC identifers: GC0XU990274 GC0XP049684 GC0XP050230 GC0XP050553 GC0XP051469

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for MAGED1:

This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family

encode tumor specific antigens that are not expressed in normal adult tissues except testis.

Although the protein encoded by this gene shares strong homology with members of the MAGE family,

it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved

in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants

encoding two different isoforms have been found for this gene. [provided by RefSeq]

UniProtKB/Swiss-Prot: MAGD1_HUMAN, Q9Y5V3

Function: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal

cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression,

and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family

members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53

phosphorylation and accumulation

Gene Wiki entry for MAGED1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the MAGED1 gene

Entrez Gene cytogenetic band: Xp11.23 Ensembl cytogenetic band: Xp11.22 HGNC cytogenetic band: Xp11.23

MAGED1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome X GeneLoc Exon Structure

GeneLoc location for GC0XP051562: (about GC identifiers)

Start:	51,562,895 bp from pter
End:	51,662,190 bp from pter
Size:	99,296 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000023.9 NT_011638.12

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: MAGD1_HUMAN, Q9Y5V3 (See protein sequence)

Recommended Name: Melanoma-associated antigen D1

Size: 778 amino acids; 86161 Da

Subunit: Interacts with DLX5, DLX7 and MSX2 and forms homomultimers. Interacts with UNC5A (By

similarity). Interacts with the p75 neurotrophin receptor

Subcellular location: Cytoplasm (By similarity). Cell membrane; Peripheral membrane protein (By

similarity). Note=Expression shifts from the cytoplasm to the plasma membrane upon stimulation

with NGF (By similarity)

Secondary accessions: Q5VSH6 Q8IZ84 Q8WY92 Q9H352 Q9HBT4 Q9UF36

Alternative splicing: 2 isoforms: Q9Y5V3-1 Q9Y5V3-2

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins (3 alternative transcripts):

NP_001005332.1 NP_001005333.1 NP_008917.3

ENSEMBL proteins:

ENSP00000364874 ENSP00000364927 ENSP00000364847 ENSP00000325333

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (MAGED1)
	Human Recombinant Proteins from Abnova (MAGED1)

OriGene Purified Recombinant Human Protein: MAGED1

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005737	cytoplasm	IEA	--
GO:0005886	plasma membrane	IEA	--
GO:0043234	protein complex	IDA	15930293

About this table

Antibodies for MAGED1:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of MAGED1
	Sigma-Aldrich Antibodies for MAGED1
	R&D Systems Antibodies for MAGED1 (NRAGE)
	Antibodies from Abcam (MAGED1), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (MAGED1)
	Novus Biologicals Antibodies for MAGED1

Assays for MAGED1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q9Y5V3

ProtoNet protein and cluster: Q9Y5V3

1 Blocks protein family: IPB002190 MAGE protein

UniProtKB/Swiss-Prot: MAGD1_HUMAN, Q9Y5V3

Similarity: Contains 1 MAGE domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MAGED1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (MAGED1)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_001005332

Applied Biosystems Silencer® siRNAs for MAGED1

Sigma-Aldrich siRNA and siRNA Panels for MAGED1

Sigma-Aldrich shRNA for MAGED1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for MAGED1
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_001005332
Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_001005332
untagged cDNA clones in CMV expression vector (see all 4): NM_001005332

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001005333

UniProtKB/Swiss-Prot: MAGD1_HUMAN, Q9Y5V3

Function: Involved in the apoptotic response after nerve growth factor (NGF) binding in neuronal

cells. Binds p75NTR and antagonizes its association with TrkA, inhibits cell cycle progression,

and facilitates p75NTR-mediated apoptosis. May act as a regulator of the function of DLX family

members. May regulate p53 transcriptional activity and inhibit cell proliferation. Enhances p53

phosphorylation and accumulation

Genatlas biochemistry entry for MAGED1:

putative melanoma antigen,family D,member 1,expressed in breast,colon,brain,fetal tissue,tumoral

cell (breast,lung,prostate,Wilms),not recognized by T cells but expressed only in tumor and

germ-line cells

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003713	transcription coactivator activity	IEA	--
GO:0005515	protein binding	IPI	15930293

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Sigma-Aldrich "Your Favorite Gene" Pathway for MAGED1 (Your Favorite Gene powered by Ingenuity)

BMP signaling pathway

GeneDecks MAGED1 for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for MAGED1

5/45 Interacting proteins for MAGED1 (ENSP00000364847³ Q9Y5V3^{1, 2}) via UniProtKB, MINT, and/or STRING (see all 45 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
XIAP	P98170²	STRING (score=.95) MINT-14016 MINT-14015
AKAP8L	Q9ULX6¹	EBI-716006, EBI-357530
ATXN10	Q9UBB4¹	EBI-716006, EBI-702390
BAT3	P46379¹	EBI-716006, EBI-347552
CALML5	Q9NZT1¹	EBI-716006, EBI-1051681

About this table

3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006357	regulation of transcription from RNA polymerase II promoter	IEA	--
GO:0042981	regulation of apoptosis	TAS	15930293
GO:0050680	negative regulation of epithelial cell proliferation	IDA	15930293

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for MAGED1

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MAGED1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (MAGED1)

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_001005332

Sigma-Aldrich siRNA and siRNA Panels for MAGED1

Sigma-Aldrich shRNA for MAGED1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001005332 NM_001005333 NM_006986

REFSEQ mRNAs for MAGED1 gene (3 alternative transcripts):

NM_001005332.1 NM_001005333.1 NM_006986.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001005332 NM_001005333 NM_006986

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 3): NM_001005332
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 3): NM_001005332
                                 untagged cDNA clones in CMV expression vector (see all 4): NM_001005332

Additional cDNA sequence:

AF124440.1 AF132205.1 AF217963.1 AF258554.1 AF300328.1 AK298574.1 AK308706.1 AK314053.1

AL133628.1 BC014070.2 BC032473.2

21 DOTS entries:

DT.101963599 DT.100059993 DT.95206453 DT.219594 DT.100880296 DT.91860774 DT.100051130 DT.100841503

DT.100880302 DT.100880308 DT.95228626 DT.100880309 DT.92463530 DT.95228623 DT.100880299 DT.91962654

DT.92463513 DT.92463514 DT.95228627 DT.100059994 DT.121317465

24/1072 AceView cDNA sequences (see all 1072 ):

BG117812 BQ678414 AF132205 BQ718306 AW238846 AI453221 BQ073348 BM977968

BU180587 BI870764 BU859148 BM988382 BM982251 BQ878984 BU528684 AI827023

BU177042 BU849518 CB132392 BQ061877 BE733072 CB158704 BQ887265 BQ681583

highest scoring ESTs for MAGED1:

W67800 AA009606 AA024851 AA025358 AA053151 AA053152 AA065176 AA065177 AA070630 AA070931

Unigene Cluster for MAGED1:

Melanoma antigen family D, 1

Hs.5258 [show with all ESTs]

Unigene Representative Sequence: NM_001005333

GeneLoc Exon Structure

5/9 Alternative Splicing Database (ASD) splice patterns (SP) for MAGED1 (see all 9 )

ExUns:	1a	·	1b	·	1c	^	2	^	3	^	4a	·	4b	·	4c	·	4d	·	4e	^	5a	·	5b	·	5c	^	6	^	7	^	8	^	9	^	10	^	11	^	12	^	13a	·	13b	^	14a	·	14b	·	14c	^	15
SP1:																					-																				-								-
SP2:									-												-																				-								-
SP3:									-								-		-		-		-		-		-		-		-		-		-						-
SP4:									-				-		-		-		-		-		-		-
SP5:									-						-		-		-		-		-

About this scheme

ECgene alternative splicing isoforms for MAGED1

4 Ensembl transcripts including schematic representations:

ENST00000375722 ENST00000375772 ENST00000375695 ENST00000326587

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

MAGED1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for MAGED1

¹ / ² / ³

4 probe-sets matching MAGED1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
41139_at²^{, 3}	U95-A	2	1.00	0.97	0.97	0.90	W26633	0.60	1.00	0.82	1
43418_at²^{, 3}	U95-B	1	0.94	1.00	0.96	1.10	W67800	1.00	1.00	1.00	1
209014_at²^{, 3}	U133-A	1	1.00	1.00	--	--	AF217963	0.80	1.00	0.91	1
209014_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CAAGATAAAT

SOURCE GeneReport for Unigene cluster: Hs.5258
Expression variation in blood from EXPOLDB for MAGED1
UniProtKB/Swiss-Prot: MAGD1_HUMAN, Q9Y5V3
Tissue specificity: Expressed in bone marrow stromal cells from both multiple myeloma patients and
healthy donors. Seems to be ubiquitously expressed

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for MAGED1 gene from 4 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	MAGED1¹	--	melanoma antigen family D, 1	93.5(n) 97.73(a)	480923 XM_846552.1 XP_851645.1
chimpanzee (Pan troglodytes)	MAGED1¹	--	melanoma antigen family D, 1	99.57(n) 99.2(a)	465641 XM_521067.2 XP_521067.2
rat (Rattus norvegicus)	Maged1¹	--	melanoma antigen, family D, 1	88.79(n) 89.4(a)	84469 NM_053409.1 NP_445861.1
mouse (Mus musculus)	Maged1^{1, 5}	X (34.60 cM)⁵	melanoma antigen, family D, 1^{1, 5}	88.62(n)¹ 88.84(a)¹	94275¹ NM_019791.2¹ NP_062765.1¹ AB029448⁵ AF319975⁵ (see all 24)

About this table Species with no ortholog for MAGED1

ENSEMBL Gene Tree for MAGED1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for MAGED1 gene

MAGED4B² LOC100132401² MAGED4² MAGED2² TRO²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/209 NCBI SNPs in MAGED1 are shown (see all 209 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 80)

AB	SNP ID	Valid	Chr X pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs12689461^1,2	A,C,H	51655555(+)	`AGAATC/ATGGAG`	3	M/L	mis¹		4		EU EA WA	418
--	rs4986564^1,2	C,H	51651973(+)	`TGGAAG/CTGTAC`	3	--	int¹ ng5¹		4		EU EA WA	384
--	rs7879220^1,2	A,C	51561760(+)	`accctA/Gtctca`	1	--	ng5¹		0	--	--	--	--
--	rs12688281^1,2	H	51561711(+)	`agtgaA/Cctatt`	1	--	ng5¹		4		EU EA WA	402
	rs12848689^1,2	H	51652587(+)	`CCCCAG/AGCCAG`	3	--	int¹ ng5¹		4		EU EA WA	416
	rs3199687^1,2	A,C,F,H	51661488(+)	`AAGCCC/AGGGCT`	3	R/R	syn¹		6		MN EU EA WA NA	670
	rs4986554^1,2	A,C,F,H	51580076(+)	`CAAAAA/GGTGTT`	1	--	int¹		4		EU EA WA	418
	rs7880576^1,2	A,C,F,H	51609719(+)	`ATACCG/TCCAGA`	1	--	int¹		7		EU EA WA NA	533
	rs5991739^1,2	A,C,F,H	51627709(+)	`GTGATG/ATATTC`	1	--	int¹		4		EU EA WA	418
	rs1048437^1,2	A,C,F,H	51632867(+)	`acttgA/Ctttct`	1	--	int¹		4		EU EA WA	418

About this table

HapMap Linkage Disequilibrium images for MAGED1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 300224

2 Novoseek disease relationships for MAGED1 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
melanoma	37.50	4	8935336 (1), 9673893 (1)
tumors	0.00	2	17453828 (2)

About this table

1 PharmGKB disease relationship for MAGED1 gene

Disease	PharmGKB Relations	PubMed IDs for articles supporting these relationships
Leukemia, Lymphocytic, Acute, L1	FA GN	12086872

About this table

Human Genome Epidemiology Navigator: MAGED1 (1 document)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/37 PubMed articles for MAGED1 gene (see all 37 ):

Identification of a new, unorthodox member of the MAGE gene family. (PubMed id 10409427)^{2, 3, 4} Pold M.... Berenson J.R. (1999)
NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor dependent apoptosis. (PubMed id 10985348)^{1, 3, 4} Salehi A.H.... Barker P.A. (2000)
hNRAGE, a human neurotrophin receptor interacting MAGE homologue, regulates p53 transcriptional activity and inhibits cell proliferation. (PubMed id 15094062)^{1, 3, 4} Wen C.-J.... Li C.-J. (2004)
A new melanoma antigen-encoding gene subfamily in human chromosome X. (PubMed id 11280991)^{1, 3, 4} Zhang C.G.... He F.C. (2001)
The DNA sequence of the human X chromosome. (PubMed id 15772651)^{3, 4} Ross M.T.... Bentley D.R. (2005)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Identification of the translational initiation codon in human MAGED1. (PubMed id 11087672)^{3, 4} Kubu C.J.... Verdi J.M. (2000)
Human NRAGE disrupts E-cadherin/beta-catenin regulated homotypic cell-cell adhesion. (PubMed id 16125672)^{1, 3} Xue B....Li C. (2005)
NRAGE associates with the anti-apoptotic factor Che-1 and regulates its degradation to induce cell death. (PubMed id 17488777)^{1, 3} Di Certo M.G....Passananti C. (2007)
Melanoma-associated antigen family protein-D1 regulation of tumor cell migration, adhesion to endothelium, and actin structures reorganization in response to hypoxic stress. (PubMed id 17453828)^{1, 3} Shen W.G....Su Q. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 9500	HGNC: 6813	AceView: MAGED1	Ensembl:ENSG00000179222	euGenes: HUgn9500
ECgene: MAGED1	H-InvDB: MAGED1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for MAGED1	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for MAGED1
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for MAGED1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for MAGED1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for MAGED1		Antibodies for MAGED1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for MAGED1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (MAGED1)
	Antibodies (MAGED1)
	Chimera RNAi (MAGED1)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (MAGED1)
	Antibodies (MAGED1)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for MAGED1

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for MAGED1

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

Random Gene From GIFtS :

about GIFtS

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
MAGED1 Gene at Home site.
Version 2.41.1
server5.xennexinc.com

MAGED1 Gene

protein-coding GIFtS: 66

Aliases &
Descriptions
for MAGED1

Summaries
for MAGED1

Genomic Location
for MAGED1

Proteins
for MAGED1

Protein Domains/
Families
for MAGED1

Gene Function
for MAGED1

Pathways & Interactions
for MAGED1

Drugs & Compounds
for MAGED1

Transcripts
for MAGED1

Expression
for MAGED1

Orthologs
for MAGED1

Paralogs
for MAGED1

SNPs/Variants
for MAGED1

Disorders & Mutations
for MAGED1

Medical News
for MAGED1

Publications
for MAGED1

Search for MAGED1

Genome Databases showing MAGED1

Other Databases showing MAGED1

Specialized Databases showing MAGED1

Licensable Technologies
for MAGED1

Services
for MAGED1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

MAGED1 Gene

protein-coding GIFtS: 66

Aliases & Descriptionsfor MAGED1

Summariesfor MAGED1

Genomic Locationfor MAGED1

Proteinsfor MAGED1

Protein Domains/Familiesfor MAGED1

Gene Functionfor MAGED1

Pathways & Interactionsfor MAGED1

Drugs & Compoundsfor MAGED1

Transcriptsfor MAGED1

Expression for MAGED1

Orthologsfor MAGED1

Paralogsfor MAGED1

SNPs/Variantsfor MAGED1

Disorders & Mutationsfor MAGED1

Medical Newsfor MAGED1

Publicationsfor MAGED1

Search for MAGED1

Genome Databases showing MAGED1

Other Databases showing MAGED1

Specialized Databases showing MAGED1

Licensable Technologiesfor MAGED1

Servicesfor MAGED1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for MAGED1

Summaries
for MAGED1

Genomic Location
for MAGED1

Proteins
for MAGED1

Protein Domains/
Families
for MAGED1

Gene Function
for MAGED1

Pathways & Interactions
for MAGED1

Drugs & Compounds
for MAGED1

Transcripts
for MAGED1

Expression
for MAGED1

Orthologs
for MAGED1

Paralogs
for MAGED1

SNPs/Variants
for MAGED1

Disorders & Mutations
for MAGED1

Medical News
for MAGED1

Publications
for MAGED1

Licensable Technologies
for MAGED1

Services
for MAGED1