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Aliases for MAGEB5 Gene

Aliases for MAGEB5 Gene

  • MAGE Family Member B5 2 3 5
  • Melanoma Antigen Family B5 2 3
  • Cancer/Testis Antigen 3.3 3 4
  • MAGE-B5 Antigen 3 4
  • CT3.3 3 4
  • MAGE Family Testis And Tumor-Specific Protein 3
  • Cancer/Testis Antigen Family 3, Member 3 3
  • Cancer/Testis Antigen Family 3 2
  • Melanoma Antigen Family B, 5 3
  • Member 3 2
  • MAGE-B5 3

External Ids for MAGEB5 Gene

Previous GeneCards Identifiers for MAGEB5 Gene

  • GC0XU900004
  • GC0XP025596
  • GC0XP025995
  • GC0XP026144
  • GC0XP023972

Summaries for MAGEB5 Gene

GeneCards Summary for MAGEB5 Gene

MAGEB5 (MAGE Family Member B5) is a Protein Coding gene. An important paralog of this gene is MAGEC3.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MAGEB5 Gene

Genomics for MAGEB5 Gene

Regulatory Elements for MAGEB5 Gene

Enhancers for MAGEB5 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MAGEB5 on UCSC Golden Path with GeneCards custom track

Genomic Location for MAGEB5 Gene

Chromosome:
X
Start:
26,216,081 bp from pter
End:
26,218,270 bp from pter
Size:
2,190 bases
Orientation:
Plus strand

Genomic View for MAGEB5 Gene

Genes around MAGEB5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MAGEB5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MAGEB5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MAGEB5 Gene

Proteins for MAGEB5 Gene

  • Protein details for MAGEB5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BZ81-MAGB5_HUMAN
    Recommended name:
    Melanoma-associated antigen B5
    Protein Accession:
    Q9BZ81

    Protein attributes for MAGEB5 Gene

    Size:
    275 amino acids
    Molecular mass:
    31906 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MAGEB5 Gene

Proteomics data for MAGEB5 Gene at MOPED

Post-translational modifications for MAGEB5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MAGEB5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MAGEB5 Gene

Domains & Families for MAGEB5 Gene

Gene Families for MAGEB5 Gene

Protein Domains for MAGEB5 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for MAGEB5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9BZ81

UniProtKB/Swiss-Prot:

MAGB5_HUMAN :
  • Contains 1 MAGE domain.
Domain:
  • Contains 1 MAGE domain.
genes like me logo Genes that share domains with MAGEB5: view

Function for MAGEB5 Gene

Phenotypes for MAGEB5 Gene

genes like me logo Genes that share phenotypes with MAGEB5: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MAGEB5 Gene

Localization for MAGEB5 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MAGEB5 Gene COMPARTMENTS Subcellular localization image for MAGEB5 gene
Compartment Confidence
cytosol 2
extracellular 1
golgi apparatus 1
mitochondrion 1
nucleus 1
peroxisome 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MAGEB5 Gene

Pathways & Interactions for MAGEB5 Gene

SuperPathways for MAGEB5 Gene

No Data Available

Interacting Proteins for MAGEB5 Gene

Gene Ontology (GO) - Biological Process for MAGEB5 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MAGEB5 Gene

Drugs & Compounds for MAGEB5 Gene

No Compound Related Data Available

Transcripts for MAGEB5 Gene

mRNA/cDNA for MAGEB5 Gene

(3) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MAGEB5 Gene

Melanoma antigen family B, 5:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MAGEB5 Gene

No ASD Table

Relevant External Links for MAGEB5 Gene

GeneLoc Exon Structure for
MAGEB5
ECgene alternative splicing isoforms for
MAGEB5

Expression for MAGEB5 Gene

mRNA expression in normal human tissues for MAGEB5 Gene

mRNA differential expression in normal tissues according to GTEx for MAGEB5 Gene

This gene is overexpressed in Testis (x51.9).

Protein differential expression in normal tissues from HIPED for MAGEB5 Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for MAGEB5 Gene



SOURCE GeneReport for Unigene cluster for MAGEB5 Gene Hs.224079

mRNA Expression by UniProt/SwissProt for MAGEB5 Gene

Q9BZ81-MAGB5_HUMAN
Tissue specificity: Expressed in testis. Not expressed in other normal tissues, but is expressed in tumors of different histological origins.
genes like me logo Genes that share expression patterns with MAGEB5: view

Protein tissue co-expression partners for MAGEB5 Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for MAGEB5 Gene

Orthologs for MAGEB5 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MAGEB5 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia LOC520085 35
  • 70.03 (n)
  • 54.84 (a)
-- 36
  • 39 (a)
OneToMany
-- 36
  • 59 (a)
OneToMany
-- 36
  • 39 (a)
OneToMany
-- 36
  • 47 (a)
OneToMany
-- 36
  • 50 (a)
OneToMany
dog
(Canis familiaris)
Mammalia MAGEB5 35
  • 71.43 (n)
  • 58.11 (a)
MAGEB5 36
  • 42 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mageb5 35
  • 68.15 (n)
  • 53.33 (a)
Mageb5 16
Gm14781 36
  • 35 (a)
OneToMany
Gm44 36
  • 33 (a)
OneToMany
Mageb5 36
  • 35 (a)
OneToMany
chimpanzee
(Pan troglodytes)
Mammalia LOC465549 35
  • 99.15 (n)
  • 98.18 (a)
rat
(Rattus norvegicus)
Mammalia Mageb17 35
  • 71.11 (n)
  • 57.14 (a)
Species with no ortholog for MAGEB5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MAGEB5 Gene

ENSEMBL:
Gene Tree for MAGEB5 (if available)
TreeFam:
Gene Tree for MAGEB5 (if available)

Paralogs for MAGEB5 Gene

genes like me logo Genes that share paralogs with MAGEB5: view

Variants for MAGEB5 Gene

Sequence variations from dbSNP and Humsavar for MAGEB5 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs747748978 -- 26,217,898(+) GCACA(C/T)TATCA reference, synonymous-codon
rs747770931 -- 26,215,624(+) AACCT(C/T)GTTCT upstream-variant-2KB
rs748454171 -- 26,217,479(+) AACAG(C/T)GTATT reference, missense
rs748763461 -- 26,215,534(+) GCCCC(A/T)AGGAG upstream-variant-2KB
rs749164814 -- 26,217,690(+) CAAGA(C/G)TGGTC reference, missense

Variation tolerance for MAGEB5 Gene

Gene Damage Index Score: 0.83; 17.45% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MAGEB5 Gene

HapMap Linkage Disequilibrium report
MAGEB5

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MAGEB5 Gene

Disorders for MAGEB5 Gene

Relevant External Links for MAGEB5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MAGEB5

No disorders were found for MAGEB5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MAGEB5 Gene

Publications for MAGEB5 Gene

  1. MAGE-B5, MAGE-B6, MAGE-C2, and MAGE-C3: four new members of the MAGE family with tumor-specific expression. (PMID: 10861452) Lucas S. … Boon T. (Int. J. Cancer 2000) 2 3 4 67

Products for MAGEB5 Gene

Sources for MAGEB5 Gene

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