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Aliases for MAGEB5 Gene

Aliases for MAGEB5 Gene

  • MAGE Family Member B5 2 3 5
  • Cancer/Testis Antigen Family 3, Member 3 2 3
  • Melanoma Antigen Family B5 2 3
  • Cancer/Testis Antigen 3.3 3 4
  • MAGE-B5 Antigen 3 4
  • CT3.3 3 4
  • MAGE Family Testis And Tumor-Specific Protein 3
  • Melanoma-Associated Antigen B5 3
  • Melanoma Antigen Family B, 5 3
  • MAGE-B5 3

External Ids for MAGEB5 Gene

Previous GeneCards Identifiers for MAGEB5 Gene

  • GC0XU900004
  • GC0XP025596
  • GC0XP025995
  • GC0XP026144
  • GC0XP023972

Summaries for MAGEB5 Gene

GeneCards Summary for MAGEB5 Gene

MAGEB5 (MAGE Family Member B5) is a Protein Coding gene. An important paralog of this gene is MAGEB4.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MAGEB5 Gene

Genomics for MAGEB5 Gene

Regulatory Elements for MAGEB5 Gene

Genomic Location for MAGEB5 Gene

26,216,081 bp from pter
26,218,270 bp from pter
2,190 bases
Plus strand

Genomic View for MAGEB5 Gene

Genes around MAGEB5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MAGEB5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MAGEB5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MAGEB5 Gene

Proteins for MAGEB5 Gene

  • Protein details for MAGEB5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Melanoma-associated antigen B5
    Protein Accession:

    Protein attributes for MAGEB5 Gene

    275 amino acids
    Molecular mass:
    31906 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MAGEB5 Gene

Post-translational modifications for MAGEB5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MAGEB5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MAGEB5 Gene

Domains & Families for MAGEB5 Gene

Gene Families for MAGEB5 Gene

Protein Domains for MAGEB5 Gene


Suggested Antigen Peptide Sequences for MAGEB5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with MAGEB5: view

No data available for UniProtKB/Swiss-Prot for MAGEB5 Gene

Function for MAGEB5 Gene

Gene Ontology (GO) - Molecular Function for MAGEB5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with MAGEB5: view

Phenotypes for MAGEB5 Gene

genes like me logo Genes that share phenotypes with MAGEB5: view

Animal Model Products

CRISPR Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MAGEB5 Gene

Localization for MAGEB5 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MAGEB5 gene
Compartment Confidence
cytosol 2
plasma membrane 1
extracellular 1
mitochondrion 1
peroxisome 1
nucleus 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for MAGEB5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with MAGEB5: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for MAGEB5 Gene

Pathways & Interactions for MAGEB5 Gene

SuperPathways for MAGEB5 Gene

No Data Available

Interacting Proteins for MAGEB5 Gene

Gene Ontology (GO) - Biological Process for MAGEB5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with MAGEB5: view

No data available for Pathways by source and SIGNOR curated interactions for MAGEB5 Gene

Drugs & Compounds for MAGEB5 Gene

No Compound Related Data Available

Transcripts for MAGEB5 Gene

mRNA/cDNA for MAGEB5 Gene

(1) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MAGEB5 Gene

Melanoma antigen family B, 5:
Representative Sequences:

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MAGEB5 Gene

No ASD Table

Relevant External Links for MAGEB5 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MAGEB5 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MAGEB5 Gene

mRNA differential expression in normal tissues according to GTEx for MAGEB5 Gene

This gene is overexpressed in Testis (x51.9).

Protein differential expression in normal tissues from HIPED for MAGEB5 Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for MAGEB5 Gene

Protein tissue co-expression partners for MAGEB5 Gene

NURSA nuclear receptor signaling pathways regulating expression of MAGEB5 Gene:


SOURCE GeneReport for Unigene cluster for MAGEB5 Gene:


mRNA Expression by UniProt/SwissProt for MAGEB5 Gene:

Tissue specificity: Expressed in testis. Not expressed in other normal tissues, but is expressed in tumors of different histological origins.

Evidence on tissue expression from TISSUES for MAGEB5 Gene

  • Lung(2)
genes like me logo Genes that share expression patterns with MAGEB5: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for MAGEB5 Gene

Orthologs for MAGEB5 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MAGEB5 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia LOC465549 34
  • 99.15 (n)
(Canis familiaris)
Mammalia MAGEB5 34 35
  • 71.43 (n)
(Rattus norvegicus)
Mammalia Mageb17 34
  • 71.11 (n)
(Bos Taurus)
Mammalia LOC520085 34
  • 70.03 (n)
-- 35
  • 59 (a)
-- 35
  • 50 (a)
-- 35
  • 47 (a)
-- 35
  • 39 (a)
-- 35
  • 39 (a)
(Mus musculus)
Mammalia Mageb5 34 16 35
  • 68.15 (n)
Gm14781 35
  • 35 (a)
Gm44 35
  • 33 (a)
Species where no ortholog for MAGEB5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MAGEB5 Gene

Gene Tree for MAGEB5 (if available)
Gene Tree for MAGEB5 (if available)

Paralogs for MAGEB5 Gene

Variants for MAGEB5 Gene

Sequence variations from dbSNP and Humsavar for MAGEB5 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1002507335 -- 26,214,480(+) TCATC(C/T)TGGGT upstream-variant-2KB
rs1003643226 -- 26,217,875(+) ACCAG(C/G)TGCCC reference, missense
rs1003705237 -- 26,216,880(+) AGGTT(C/T)CCCAA intron-variant
rs1004475157 -- 26,214,304(+) TTGAG(C/T)TGCCT upstream-variant-2KB
rs1008316514 -- 26,216,148(+) AGTGG(A/G)AACAC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MAGEB5 Gene

Variant ID Type Subtype PubMed ID
nsv522405 CNV gain 19592680

Variation tolerance for MAGEB5 Gene

Gene Damage Index Score: 0.83; 17.45% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MAGEB5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MAGEB5 Gene

Disorders for MAGEB5 Gene

Relevant External Links for MAGEB5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MAGEB5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MAGEB5 Gene

Publications for MAGEB5 Gene

  1. MAGE-B5, MAGE-B6, MAGE-C2, and MAGE-C3: four new members of the MAGE family with tumor-specific expression. (PMID: 10861452) Lucas S. … Boon T. (Int. J. Cancer 2000) 2 3 4 64
  2. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 4 64

Products for MAGEB5 Gene

Sources for MAGEB5 Gene

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