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Aliases for MAGEB5 Gene

Aliases for MAGEB5 Gene

  • Melanoma Antigen Family B5 2 3
  • Cancer/Testis Antigen 3.3 3 4
  • MAGE-B5 Antigen 3 4
  • CT3.3 3 4
  • MAGE Family Testis And Tumor-Specific Protein 3
  • Cancer/Testis Antigen Family 3, Member 3 3
  • Cancer/Testis Antigen Family 3 2
  • Melanoma-Associated Antigen B5 3
  • Melanoma Antigen Family B, 5 3
  • Member 3 2
  • MAGE-B5 3

External Ids for MAGEB5 Gene

Previous GeneCards Identifiers for MAGEB5 Gene

  • GC0XU900004
  • GC0XP025596
  • GC0XP025995
  • GC0XP026144
  • GC0XP023972

Summaries for MAGEB5 Gene

GeneCards Summary for MAGEB5 Gene

MAGEB5 (Melanoma Antigen Family B5) is a Protein Coding gene. An important paralog of this gene is MAGED1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MAGEB5 Gene

Genomics for MAGEB5 Gene

Regulatory Elements for MAGEB5 Gene

Genomic Location for MAGEB5 Gene

26,216,169 bp from pter
26,218,270 bp from pter
2,102 bases
Plus strand

Genomic View for MAGEB5 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MAGEB5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MAGEB5 Gene

Proteins for MAGEB5 Gene

  • Protein details for MAGEB5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Melanoma-associated antigen B5
    Protein Accession:
    Secondary Accessions:

    Protein attributes for MAGEB5 Gene

    275 amino acids
    Molecular mass:
    31906 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MAGEB5 Gene

Proteomics data for MAGEB5 Gene at MOPED

Post-translational modifications for MAGEB5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MAGEB5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MAGEB5 Gene

Domains for MAGEB5 Gene

Protein Domains for MAGEB5 Gene


Suggested Antigen Peptide Sequences for MAGEB5 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 MAGE domain.
  • Contains 1 MAGE domain.
genes like me logo Genes that share domains with MAGEB5: view

No data available for Gene Families for MAGEB5 Gene

Function for MAGEB5 Gene

Gene Ontology (GO) - Molecular Function for MAGEB5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003674 molecular_function ND --
genes like me logo Genes that share ontologies with MAGEB5: view

Phenotypes for MAGEB5 Gene

GenomeRNAi human phenotypes for MAGEB5:
genes like me logo Genes that share phenotypes with MAGEB5: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MAGEB5 Gene

Localization for MAGEB5 Gene

Subcellular locations from

Jensen Localization Image for MAGEB5 Gene COMPARTMENTS Subcellular localization image for MAGEB5 gene
Compartment Confidence
cytosol 2
extracellular 1
golgi apparatus 1
mitochondrion 1
nucleus 1
peroxisome 1
plasma membrane 1

Gene Ontology (GO) - Cellular Components for MAGEB5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005575 cellular_component ND --
genes like me logo Genes that share ontologies with MAGEB5: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for MAGEB5 Gene

Pathways for MAGEB5 Gene

SuperPathways for MAGEB5 Gene

No Data Available

Interacting Proteins for MAGEB5 Gene

Gene Ontology (GO) - Biological Process for MAGEB5 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008150 biological_process ND --
genes like me logo Genes that share ontologies with MAGEB5: view

No data available for Pathways by source for MAGEB5 Gene

Transcripts for MAGEB5 Gene

mRNA/cDNA for MAGEB5 Gene

(3) REFSEQ mRNAs :
(0) Additional mRNA sequences :
(2) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MAGEB5 Gene

Melanoma antigen family B, 5:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MAGEB5

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MAGEB5 Gene

No ASD Table

Relevant External Links for MAGEB5 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MAGEB5 Gene

mRNA expression in normal human tissues for MAGEB5 Gene

mRNA differential expression in normal tissues according to GTEx for MAGEB5 Gene

This gene is overexpressed in Testis (51.9).

Protein differential expression in normal tissues for MAGEB5 Gene

This gene is overexpressed in Platelet (69.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for MAGEB5 Gene

SOURCE GeneReport for Unigene cluster for MAGEB5 Gene Hs.224079

mRNA Expression by UniProt/SwissProt for MAGEB5 Gene

Tissue specificity: Expressed in testis. Not expressed in other normal tissues, but is expressed in tumors of different histological origins
genes like me logo Genes that share expressions with MAGEB5: view

Expression partners for MAGEB5 Gene

* - Elite partner

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery for MAGEB5 Gene

Orthologs for MAGEB5 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MAGEB5 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC520085 35
  • 70.03 (n)
  • 54.84 (a)
-- 36
  • 39 (a)
-- 36
  • 59 (a)
-- 36
  • 39 (a)
-- 36
  • 47 (a)
-- 36
  • 50 (a)
(Canis familiaris)
Mammalia MAGEB5 35
  • 71.43 (n)
  • 58.11 (a)
  • 42 (a)
(Mus musculus)
Mammalia Mageb5 35
  • 68.15 (n)
  • 53.33 (a)
Gm14781 36
  • 35 (a)
Gm44 36
  • 33 (a)
Mageb5 36
  • 35 (a)
(Pan troglodytes)
Mammalia LOC465549 35
  • 99.15 (n)
  • 98.18 (a)
(Rattus norvegicus)
Mammalia Mageb17 35
  • 71.11 (n)
  • 57.14 (a)
Species with no ortholog for MAGEB5:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MAGEB5 Gene

Gene Tree for MAGEB5 (if available)
Gene Tree for MAGEB5 (if available)

Paralogs for MAGEB5 Gene

genes like me logo Genes that share paralogs with MAGEB5: view

Variants for MAGEB5 Gene

Sequence variations from dbSNP and Humsavar for MAGEB5 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type MAF
rs1476724 -- 26,215,060(-) AAACC(A/G)TTGCT upstream-variant-2KB
rs1860012 -- 26,214,764(-) TTTGA(A/G)GTAGT upstream-variant-2KB
rs2190738 -- 26,214,528(-) TAAAC(G/T)TTGGG upstream-variant-2KB
rs2215073 -- 26,214,197(-) ACCCT(C/G)CCTTA upstream-variant-2KB
rs3054518 -- 26,215,068(-) AAAAA(-/AA)GAAAA upstream-variant-2KB

Relevant External Links for MAGEB5 Gene

HapMap Linkage Disequilibrium report
Locus Specific Mutation Databases (LSDB)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MAGEB5 Gene

Disorders for MAGEB5 Gene

No disorders were found for MAGEB5 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MAGEB5 Gene

Publications for MAGEB5 Gene

  1. MAGE-B5, MAGE-B6, MAGE-C2, and MAGE-C3: four new members of the MAGE family with tumor-specific expression. (PMID: 10861452) Lucas S. … Boon T. (Int. J. Cancer 2000) 2 3 4
  2. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 4

Products for MAGEB5 Gene

Sources for MAGEB5 Gene

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