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Aliases for MAGEB17 Gene

Aliases for MAGEB17 Gene

  • MAGE Family Member B17 2 3 5
  • Melanoma Antigen Family B, 17 (Pseudogene) 2
  • Melanoma Antigen Family B17 2

External Ids for MAGEB17 Gene

Previous GeneCards Identifiers for MAGEB17 Gene

  • GC0XM015945
  • GC0XU900743
  • GC0XP016095
  • GC0XP013939

Summaries for MAGEB17 Gene

GeneCards Summary for MAGEB17 Gene

MAGEB17 (MAGE Family Member B17) is a Protein Coding gene. An important paralog of this gene is MAGEB4.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MAGEB17 Gene

Genomics for MAGEB17 Gene

Regulatory Elements for MAGEB17 Gene

Enhancers for MAGEB17 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH0XF016198 0.4 ENCODE 13.5 +31.8 31819 1.1 SPI1 LOC102724124 MAGEB17 ZRSR2 RPL6P30
GH0XF016215 0.2 ENCODE 12.8 +48.5 48538 1.9 LOC102724124 MAGEB17 ZRSR2 RPL6P30 GC0XP016374
GH0XF016159 0.5 ENCODE 0.4 -6.7 -6650 2.1 JUND SIN3A FOS TCF7L2 GRPR ZRSR2 MAGEB17
GH0XF016122 0.9 Ensembl ENCODE 0.2 -44.0 -44016 1.0 CTCF ATF1 WRNIP1 REST RAD21 RFX5 NFYB ZNF143 SMC3 GRPR MAGEB17
GH0XF016158 0.3 FANTOM5 0.4 -8.8 -8821 0.4 GRPR MAGEB17
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around MAGEB17 on UCSC Golden Path with GeneCards custom track

Genomic Location for MAGEB17 Gene

16,167,481 bp from pter
16,172,097 bp from pter
4,617 bases
Plus strand

Genomic View for MAGEB17 Gene

Genes around MAGEB17 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MAGEB17 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MAGEB17 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MAGEB17 Gene

Proteins for MAGEB17 Gene

  • Protein details for MAGEB17 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Melanoma-associated antigen B17
    Protein Accession:
    Secondary Accessions:
    • A6NE98

    Protein attributes for MAGEB17 Gene

    336 amino acids
    Molecular mass:
    37578 Da
    Quaternary structure:
    No Data Available
    • Sequence=EAW98911.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for MAGEB17 Gene

Post-translational modifications for MAGEB17 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MAGEB17 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MAGEB17 Gene

Domains & Families for MAGEB17 Gene

Gene Families for MAGEB17 Gene

Protein Domains for MAGEB17 Gene


Suggested Antigen Peptide Sequences for MAGEB17 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 MAGE domain.
  • Contains 1 MAGE domain.
genes like me logo Genes that share domains with MAGEB17: view

Function for MAGEB17 Gene

Phenotypes for MAGEB17 Gene

genes like me logo Genes that share phenotypes with MAGEB17: view

Animal Model Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MAGEB17 Gene

Localization for MAGEB17 Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MAGEB17 gene
Compartment Confidence
nucleus 3
plasma membrane 1
mitochondrion 1
endoplasmic reticulum 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MAGEB17 Gene

Pathways & Interactions for MAGEB17 Gene

SuperPathways for MAGEB17 Gene

No Data Available

Interacting Proteins for MAGEB17 Gene

Gene Ontology (GO) - Biological Process for MAGEB17 Gene


No data available for Pathways by source and SIGNOR curated interactions for MAGEB17 Gene

Transcripts for MAGEB17 Gene

mRNA/cDNA for MAGEB17 Gene

(2) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MAGEB17 Gene

No ASD Table

Relevant External Links for MAGEB17 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MAGEB17 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MAGEB17 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for MAGEB17 Gene

This gene is overexpressed in Esophagus - Gastroesophageal Junction (x9.3), Pancreas (x7.9), Testis (x7.8), and Esophagus - Muscularis (x6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for MAGEB17 Gene

NURSA nuclear receptor signaling pathways regulating expression of MAGEB17 Gene:

genes like me logo Genes that share expression patterns with MAGEB17: view

No data available for Protein differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for MAGEB17 Gene

Orthologs for MAGEB17 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MAGEB17 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia MAGEB17 34 35
  • 98.31 (n)
(Bos Taurus)
Mammalia LOC618686 34
  • 68.94 (n)
-- 35
  • 49 (a)
(Canis familiaris)
Mammalia LOC100684355 34
  • 65.22 (n)
MAGEB10 35
  • 47 (a)
(Mus musculus)
Mammalia Gm5072 34 16
  • 61.24 (n)
Species where no ortholog for MAGEB17 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MAGEB17 Gene

Gene Tree for MAGEB17 (if available)
Gene Tree for MAGEB17 (if available)

Paralogs for MAGEB17 Gene

Variants for MAGEB17 Gene

Sequence variations from dbSNP and Humsavar for MAGEB17 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs10856273 -- 16,172,300(+) AGGCC(C/T)TACCT utr-variant-3-prime
rs11094694 -- 16,166,637(+) ATACC(A/G)TCATC intron-variant, upstream-variant-2KB
rs11094695 -- 16,166,918(+) CGTTC(A/T)GGAAT intron-variant, upstream-variant-2KB
rs111842395 -- 16,168,491(+) TTGGG(A/G)CGTGA intron-variant, upstream-variant-2KB
rs112740120 -- 16,168,572(+) TCCCA(C/T)CCTGA intron-variant, upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for MAGEB17 Gene

Variant ID Type Subtype PubMed ID
nsv436917 CNV insertion 17901297

Variation tolerance for MAGEB17 Gene

Gene Damage Index Score: 0.71; 15.13% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MAGEB17 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MAGEB17 Gene

Disorders for MAGEB17 Gene

Relevant External Links for MAGEB17

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for MAGEB17 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MAGEB17 Gene

Publications for MAGEB17 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 64
  2. An overview of the MAGE gene family with the identification of all human members of the family. (PMID: 11454705) Chomez P. … Lucas S. (Cancer Res. 2001) 2 3 64

Products for MAGEB17 Gene

Sources for MAGEB17 Gene

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