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MAGEB17 Gene(Protein Coding)

MAGE Family Member B17

GCID:
GC0XP016183
GIFtS:
34
Genes Participants
UDN Logo

Aliases for MAGEB17 Gene

Aliases for MAGEB17 Gene

  • MAGE Family Member B17 2 3 5
  • Melanoma Antigen Family B, 17 (Pseudogene) 2
  • Melanoma Antigen Family B17 2

External Ids for MAGEB17 Gene

Previous GeneCards Identifiers for MAGEB17 Gene

  • GC0XM015945
  • GC0XU900743
  • GC0XP016095
  • GC0XP013939

Summaries for MAGEB17 Gene

GeneCards Summary for MAGEB17 Gene

MAGEB17 (MAGE Family Member B17) is a Protein Coding gene. An important paralog of this gene is MAGEC3.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MAGEB17 Gene

Genomics for MAGEB17 Gene

Products:

  1. Regulatory Element

Regulatory Elements for MAGEB17 Gene

Enhancers for MAGEB17 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MAGEB17 on UCSC Golden Path with GeneCards custom track

Transcription factor binding sites by QIAGEN in the MAGEB17 gene promoter:

Genomic Location for MAGEB17 Gene

Chromosome:
X
Start:
16,167,481 bp from pter
End:
16,172,097 bp from pter
Size:
4,617 bases
Orientation:
Plus strand

Genomic View for MAGEB17 Gene

Genes around MAGEB17 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MAGEB17 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MAGEB17 Gene
GeneLoc Logo Genomic Neighborhood • Exon Structure • Gene Density

RefSeq DNA sequence for MAGEB17 Gene

Proteins for MAGEB17 Gene

Products:

  1. Antibody
  2. Protein
  3. Assay

  • Protein details for MAGEB17 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A8MXT2-MAGBH_HUMAN
    Recommended name:
    Melanoma-associated antigen B17
    Protein Accession:
    A8MXT2
    Secondary Accessions:
    • A6NE98

    Protein attributes for MAGEB17 Gene

    Size:
    336 amino acids
    Molecular mass:
    37578 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=EAW98911.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for MAGEB17 Gene

Proteomics data for MAGEB17 Gene at MOPED

Protein Expression for MAGEB17 Gene

See protein expression from ProteomicsDB, MOPED, PaxDb, and MaxQB

Post-translational modifications for MAGEB17 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MAGEB17 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MAGEB17 Gene

Domains & Families for MAGEB17 Gene

Gene Families for MAGEB17 Gene

HGNC:

Protein Domains for MAGEB17 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for MAGEB17 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A8MXT2

UniProtKB/Swiss-Prot:

MAGBH_HUMAN :
  • Contains 1 MAGE domain.
Domain:
  • Contains 1 MAGE domain.
genes like me logo Genes that share domains with MAGEB17: view

Function for MAGEB17 Gene

Products:

  1. Animal Model
  2. CRISPR
  3. miRNA
  4. Inhibitory RNA
  5. Clone
  6. Cell Line
  7. Flow Cytometry

Phenotypes for MAGEB17 Gene

GenomeRNAi human phenotypes for MAGEB17:
genes like me logo Genes that share phenotypes with MAGEB17: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MAGEB17 Gene

Localization for MAGEB17 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MAGEB17 Gene COMPARTMENTS Subcellular localization image for MAGEB17 gene
Compartment Confidence
nucleus 3
cytosol 1
endoplasmic reticulum 1
mitochondrion 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MAGEB17 Gene

Pathways & Interactions for MAGEB17 Gene

SuperPathways for MAGEB17 Gene

PathCards logoMore details on SuperPathways for MAGEB17
No Data Available

Interacting Proteins for MAGEB17 Gene

STRING Interaction Network Preview (showing 5 interactants - click image to see 15)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000382883%0d%0a9606.ENSP00000287437%0d%0a9606.ENSP00000323439%0d%0a9606.ENSP00000355077%0d%0a9606.ENSP00000354957%0d%0a9606.ENSP00000358019%0d%0a
Selected Interacting proteins: ENSP00000382883 for MAGEB17 Gene via STRING

Gene Ontology (GO) - Biological Process for MAGEB17 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MAGEB17 Gene

Drugs & Compounds for MAGEB17 Gene

Products:

  1. Drug
No Compound Related Data Available

Transcripts for MAGEB17 Gene

Products:

  1. CRISPR
  2. miRNA
  3. Inhibitory RNA
  4. Clone
  5. Flow Cytometry

mRNA/cDNA for MAGEB17 Gene

(2) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MAGEB17 Gene

No ASD Table

Relevant External Links for MAGEB17 Gene

GeneLoc Exon Structure for
MAGEB17
ECgene alternative splicing isoforms for
MAGEB17

Expression for MAGEB17 Gene

Products:

  1. Primer

mRNA expression in normal human tissues for MAGEB17 Gene

mRNA expression in normal human tissues for MAGEB17 Gene
mRNA expression by GTEx for MAGEB17 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for MAGEB17 Gene

This gene is overexpressed in Esophagus - Gastroesophageal Junction (x9.3), Pancreas (x7.9), Testis (x7.8), and Esophagus - Muscularis (x6.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for MAGEB17 Gene



genes like me logo Genes that share expression patterns with MAGEB17: view

No data available for Protein differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MAGEB17 Gene

Orthologs for MAGEB17 Gene

This gene was present in the common ancestor of mammals.

Orthologs for MAGEB17 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
 Mammalia LOC618686 35
  • 68.94 (n)
  • 55.68 (a)
-- 36
  • 49 (a)
 ManyToMany
dog
(Canis familiaris)
 Mammalia LOC100684355 35
  • 65.22 (n)
  • 55.84 (a)
MAGEB10 36
  • 47 (a)
 ManyToMany
mouse
(Mus musculus)
 Mammalia Gm5072 35
  • 61.24 (n)
  • 46.1 (a)
Gm5072 16
chimpanzee
(Pan troglodytes)
 Mammalia MAGEB17 35
  • 98.31 (n)
  • 97.32 (a)
MAGEB17 36
  • 97 (a)
 OneToOne
Species with no ortholog for MAGEB17:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MAGEB17 Gene

ENSEMBL:
Gene Tree for MAGEB17 (if available)
TreeFam:
Gene Tree for MAGEB17 (if available)

Paralogs for MAGEB17 Gene

Paralogs for MAGEB17 Gene

(33) SIMAP similar genes for MAGEB17 Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with MAGEB17: view

Variants for MAGEB17 Gene

Sequence variations from dbSNP and Humsavar for MAGEB17 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs748019913 -- 16,171,200(+) CCTGT(A/G)GGGTC reference, stop-gained
rs748330774 -- 16,172,461(+) AATGA(C/T)ATTTT downstream-variant-500B
rs748468131 -- 16,170,182(+) AACTT(C/T)CTCCC intron-variant
rs748631594 -- 16,171,725(+) AATAG(C/T)GATTG downstream-variant-500B, utr-variant-3-prime
rs748992626 -- 16,171,354(+) AGGGA(G/T)AGCGC reference, missense

Variation tolerance for MAGEB17 Gene

Gene Damage Index Score: 0.71; 15.13% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for MAGEB17 Gene

Disorders for MAGEB17 Gene

Relevant External Links for MAGEB17

Genetic Association Database (GAD)
MAGEB17
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MAGEB17

No disorders were found for MAGEB17 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MAGEB17 Gene

Publications for MAGEB17 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 67
  2. An overview of the MAGE gene family with the identification of all human members of the family. (PMID: 11454705) Chomez P. … Lucas S. (Cancer Res. 2001) 2 3

Products for MAGEB17 Gene

Sources for MAGEB17 Gene

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