Aliases for MAGEB17 Gene
Aliases for MAGEB17 Gene
External Ids for MAGEB17 Gene
- HGNC: 17418
- Entrez Gene: 645864
- Ensembl: ENSG00000182798
- OMIM: 300763
- UniProtKB: A8MXT2
Previous GeneCards Identifiers for MAGEB17 Gene
- GC0XM015945
- GC0XU900743
- GC0XP016095
- GC0XP013939
Summaries for MAGEB17 Gene
GeneCards Summary for MAGEB17 Gene
MAGEB17 (MAGE Family Member B17) is a Protein Coding gene. An important paralog of this gene is MAGEB4.
Additional gene information for MAGEB17 Gene
No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MAGEB17 Gene
Genomics for MAGEB17 Gene
GeneHancer (GH) Regulatory Elements for MAGEB17 Gene
Promoters and enhancers for MAGEB17 Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH0XI016215 | Enhancer | 0.7 | ENCODE dbSUPER | 12.8 | +48.5 | 48538 | 1.9 | SP1 TEAD4 CBFA2T3 ATF2 EZH2 | MAGEB17 LOC102724124 ZRSR2 RPL6P30 GC0XP016374 | |
| GH0XI016198 | Enhancer | 0.5 | ENCODE dbSUPER | 13.5 | +31.8 | 31819 | 1.1 | SPI1 | RPL6P30 LOC102724124 MAGEB17 ZRSR2 | |
| GH0XI016211 | Enhancer | 0.5 | dbSUPER | 12.5 | +44.7 | 44706 | 0.6 | CTCF JUND REST FOS RAD21 | MAGEB17 LOC102724124 GRPR ZRSR2 RPL6P30 GC0XP016374 | |
| GH0XI016122 | Promoter/Enhancer | 1.1 | EPDnew ENCODE | 0.3 | -44.0 | -44015 | 1 | CTCF ATF1 TRIM22 SIN3A REST RAD21 RFX5 NFYB ZNF143 SMC3 | GRPR MAGEB17 | |
| GH0XI016159 | Enhancer | 0.5 | ENCODE | 0.4 | -6.7 | -6650 | 2.1 | SP1 JUND POLR2A FOSL2 FOS | GRPR ZRSR2 MAGEB17 LOC102724124 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data dump
GeneHancers around MAGEB17 on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Locations for MAGEB17 Gene
Genomic Locations for MAGEB17 Gene
- chrX:16,167,481-16,172,097
- (GRCh38/hg38)
- Size:
- 4,617 bases
- Orientation:
- Plus strand
- chrX:16,185,604-16,189,587
- (GRCh37/hg19)
Genomic View for MAGEB17 Gene
Genes around MAGEB17 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- Xp22.2 by Ensembl
- Xp22.2 by Entrez Gene
- Xp22.2 by HGNC
MAGEB17 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MAGEB17 Gene
Proteins for MAGEB17 Gene
-
Protein details for MAGEB17 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- A8MXT2-MAGBH_HUMAN
- Recommended name:
- Melanoma-associated antigen B17
- Protein Accession:
- A8MXT2
- A6NE98
Protein attributes for MAGEB17 Gene
- Size:
- 336 amino acids
- Molecular mass:
- 37578 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=EAW98911.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
Protein Expression for MAGEB17 Gene
Post-translational modifications for MAGEB17 Gene
No Post-translational modifications
Other Protein References for MAGEB17 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for MAGEB17
- Invitrogen Antibodies for MAGEB17
- Search GeneTex for Antibodies for MAGEB17
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for MAGEB17
- Origene Custom Protein Services for MAGEB17
- Novus Biologicals proteins for MAGEB17
- Search GeneTex for Proteins for MAGEB17
Assay Products
No data available for DME Specific Peptides for MAGEB17 Gene
Domains & Families for MAGEB17 Gene
Gene Families for MAGEB17 Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Suggested Antigen Peptide Sequences for MAGEB17 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for MAGEB17 Gene
Function for MAGEB17 Gene
Phenotypes for MAGEB17 Gene
- GenomeRNAi human phenotypes for MAGEB17:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MAGEB17
-
- Search ViGene Biosciences for MAGEB17
CRISPR Products
- Browse CRISPR knockouts for MAGEB17
- genomics-online: gRNA clones - Search results for 11 available MAGEB17 gene related products
- Overview of 11 available MAGEB17 gene related products
- Applied Biological Materials CRISPR for MAGEB17
-
Vectors and viruses for KO, Activation, Repression, and more
- GenScript: Design CRISPR guide RNA sequences for MAGEB17
miRNA Products
- Search ViGene Biosciences for MAGEB17
Inhibitory RNA Products
- genomics-online: shRNA clones - Search results for 11 available MAGEB17 gene related products
- Overview of 11 available MAGEB17 gene related products
- Search ViGene Biosciences for MAGEB17
Clone Products
- VectorBuilder custom plasmid, inducible vectors for MAGEB17
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MAGEB17
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MAGEB17
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MAGEB17 Gene
Localization for MAGEB17 Gene
| Compartment | Confidence |
|---|---|
| nucleus | 3 |
| plasma membrane | 1 |
| mitochondrion | 1 |
| endoplasmic reticulum | 1 |
| cytosol | 1 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MAGEB17 Gene
Pathways & Interactions for MAGEB17 Gene
No Data Available
Interacting Proteins for MAGEB17 Gene
No data available for Pathways by source and SIGNOR curated interactions for MAGEB17 Gene
Transcripts for MAGEB17 Gene
mRNA/cDNA for MAGEB17 Gene
- (2) REFSEQ mRNAs :
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
CRISPR Products
- Browse CRISPR knockouts for MAGEB17
- genomics-online: gRNA clones - Search results for 11 available MAGEB17 gene related products
- Overview of 11 available MAGEB17 gene related products
- Applied Biological Materials CRISPR for MAGEB17
-
Vectors and viruses for KO, Activation, Repression, and more
- GenScript: Design CRISPR guide RNA sequences for MAGEB17
miRNA Products
- Search ViGene Biosciences for MAGEB17
Inhibitory RNA Products
- genomics-online: shRNA clones - Search results for 11 available MAGEB17 gene related products
- Overview of 11 available MAGEB17 gene related products
- Search ViGene Biosciences for MAGEB17
Clone Products
- VectorBuilder custom plasmid, inducible vectors for MAGEB17
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MAGEB17
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Applied Biological Materials Clones for MAGEB17
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Expression for MAGEB17 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Adipose (Muscoskeletal System)
- Mesenchymal Stem Cells Subcutaneous White Adipose
-
Mesenchymal Stem Cells
- Mesenchymal Stem Cells Subcutaneous White Adipose
mRNA differential expression in normal tissues according to GTEx for MAGEB17 Gene
This gene is overexpressed in Esophagus - Gastroesophageal Junction (x9.3), Pancreas (x7.9), Testis (x7.8), and Esophagus - Muscularis (x6.4).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for MAGEB17 Gene
NURSA nuclear receptor signaling pathways regulating expression of MAGEB17 Gene:
MAGEB17Primer Products
No data available for Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MAGEB17 Gene
Orthologs for MAGEB17 Gene
This gene was present in the common ancestor of mammals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | MAGEB17 33 34 |
|
||
| cow (Bos Taurus) |
Mammalia | LOC618686 33 |
|
||
| -- 34 |
|
ManyToMany | |||
| dog (Canis familiaris) |
Mammalia | LOC100684355 33 |
|
||
| MAGEB10 34 |
|
ManyToMany | |||
| mouse (Mus musculus) |
Mammalia | Gm5072 33 16 |
|
- Species where no ortholog for MAGEB17 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- chicken (Gallus gallus)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rat (Rattus norvegicus)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
- zebrafish (Danio rerio)
Paralogs for MAGEB17 Gene
Paralogs for MAGEB17 Gene
- MAGEB4 5
- MAGEB1 5
- MAGEB18 5
- MAGEB10 5
- MAGEB2 5
- MAGEB3 5
- MAGEB6B 5
- MAGEB6 5
- MAGEB16 5
- MAGEA10 5
- MAGEA8 5
- MAGEC2 5
- MAGEA11 5
- MAGEA4 5
- MAGEA1 5
- MAGEC1 5
- MAGEA9 5
- MAGEA9B 5
- MAGEA2 5
- MAGEA2B 5
- MAGEA3 5
- MAGEA12 5
- MAGEA6 5
- MAGEB5 5
- MAGEL2 5
- MAGED4 5
- MAGED4B 5
- TRO 5
- MAGED2 5
- MAGED1 5
- MAGEF1 5
- NSMCE3 5
- MAGEC3 5
- MAGEE2 5
- MAGEE1 5
- NDN 5
(33) SIMAP similar genes for MAGEB17 Gene using alignment to 1 proteins:
Variants for MAGEB17 Gene
| SNP ID | Clin | Chr 0X pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000823851 | -- | 16,171,188(+) | A/G | coding_sequence_variant, missense_variant | |
| rs1000925813 | -- | 16,170,786(+) | T/C | coding_sequence_variant, missense_variant | |
| rs1000966987 | -- | 16,168,881(+) | G/A | 5_prime_UTR_variant, intron_variant | |
| rs1001510017 | -- | 16,166,451(+) | G/A | upstream_transcript_variant | |
| rs1001972277 | -- | 16,170,766(+) | G/A | coding_sequence_variant, synonymous_variant |
Gene Damage Index Score:
0.71;
15.13% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MAGEB17 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MAGEB17
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MAGEB17 Gene
Disorders for MAGEB17 Gene
Additional Disease Information for MAGEB17
- Genetic Association Database
- (GAD)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for MAGEB17 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MAGEB17 Gene
Publications for MAGEB17 Gene
- The DNA sequence of the human X chromosome. (PMID: 15772651) Ross MT … Bentley DR (Nature 2005) 3 4 58
- An overview of the MAGE gene family with the identification of all human members of the family. (PMID: 11454705) Chomez P … Lucas S (Cancer research 2001) 2 3 58
Products for MAGEB17 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
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- Browse Cell Culture Products
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- Browse Immunoprecipitation Assays
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- Browse Proteome Profiler Antibody Arrays
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- Custom Antibody Services
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Next-day shipping of latest version cDNA ORF clones for MAGEB17 in any vector
- GenScript Custom Purified and Recombinant Proteins Services for MAGEB17
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- GenScript Custom overexpressing Cell Line Services for MAGEB17
- GenScript: Design CRISPR guide RNA sequences for MAGEB17
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Sino Biological Transfection Reagent
- Sino Biological Anti-His Tag Antibody
- Novus Biologicals Antibodies for MAGEB17
- Novus Biologicals proteins for MAGEB17
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies at Cloud-Clone Corp.
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- Browse Knockouts at Cloud-Clone Corp.
- Browse Knockins at Cloud-Clone Corp.
- Cloud-Clone Corp. disease models service
- Browse cDNA clones at Cloud-Clone Corp.
- Browse primers at Cloud-Clone Corp.
- Cloud-Clone Corp. primary cells service
- Invitrogen Antibodies for MAGEB17
- Cyagen custom Knockout/knockin (KOKI) mouse models for MAGEB17
- VectorBuilder custom plasmid, inducible vectors for MAGEB17
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MAGEB17
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneTex for Antibodies for MAGEB17
- Search GeneTex for Proteins for MAGEB17
- genomics-online: cdna clones - Search results for 11 available MAGEB17 gene related products
- Overview of 11 available MAGEB17 gene related products
- orf clones - Search results for 11 available MAGEB17 gene related products
- Overview of 11 available MAGEB17 gene related products
- genomics-online: gRNA clones - Search results for 11 available MAGEB17 gene related products
- Overview of 11 available MAGEB17 gene related products
- genomics-online: primer clones - Search results for 11 available MAGEB17 gene related products
- Overview of 11 available MAGEB17 gene related products
- genomics-online: shRNA clones - Search results for 11 available MAGEB17 gene related products
- Overview of 11 available MAGEB17 gene related products
Sources for MAGEB17 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew