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Aliases for MAGEB16 Gene

Aliases for MAGEB16 Gene

  • MAGE Family Member B16 2 3 5
  • Melanoma Antigen Family B, 16 (Pseudogene) 2
  • Melanoma Antigen Family B16 2
  • MAGE-B16 Antigen 4

External Ids for MAGEB16 Gene

Previous GeneCards Identifiers for MAGEB16 Gene

  • GC0XU900549
  • GC0XP035726
  • GC0XP033557

Summaries for MAGEB16 Gene

GeneCards Summary for MAGEB16 Gene

MAGEB16 (MAGE Family Member B16) is a Protein Coding gene. An important paralog of this gene is MAGEC3.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MAGEB16 Gene

Genomics for MAGEB16 Gene

Regulatory Elements for MAGEB16 Gene

Enhancers for MAGEB16 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around MAGEB16 on UCSC Golden Path with GeneCards custom track

Genomic Location for MAGEB16 Gene

Chromosome:
X
Start:
35,795,541 bp from pter
End:
35,803,762 bp from pter
Size:
8,222 bases
Orientation:
Plus strand

Genomic View for MAGEB16 Gene

Genes around MAGEB16 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MAGEB16 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MAGEB16 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MAGEB16 Gene

Proteins for MAGEB16 Gene

  • Protein details for MAGEB16 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A2A368-MAGBG_HUMAN
    Recommended name:
    Melanoma-associated antigen B16
    Protein Accession:
    A2A368
    Secondary Accessions:
    • A8MU30

    Protein attributes for MAGEB16 Gene

    Size:
    324 amino acids
    Molecular mass:
    36178 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAM20853.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for MAGEB16 Gene

Proteomics data for MAGEB16 Gene at MOPED

Post-translational modifications for MAGEB16 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MAGEB16 Gene

No data available for DME Specific Peptides for MAGEB16 Gene

Domains & Families for MAGEB16 Gene

Gene Families for MAGEB16 Gene

Protein Domains for MAGEB16 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for MAGEB16 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

A2A368

UniProtKB/Swiss-Prot:

MAGBG_HUMAN :
  • Contains 1 MAGE domain.
Domain:
  • Contains 1 MAGE domain.
genes like me logo Genes that share domains with MAGEB16: view

Function for MAGEB16 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MAGEB16 Gene

Localization for MAGEB16 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for MAGEB16 Gene COMPARTMENTS Subcellular localization image for MAGEB16 gene
Compartment Confidence
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for MAGEB16 Gene

Pathways & Interactions for MAGEB16 Gene

SuperPathways for MAGEB16 Gene

No Data Available

Interacting Proteins for MAGEB16 Gene

Gene Ontology (GO) - Biological Process for MAGEB16 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MAGEB16 Gene

Drugs & Compounds for MAGEB16 Gene

No Compound Related Data Available

Transcripts for MAGEB16 Gene

mRNA/cDNA for MAGEB16 Gene

(4) REFSEQ mRNAs :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MAGEB16 Gene

No ASD Table

Relevant External Links for MAGEB16 Gene

GeneLoc Exon Structure for
MAGEB16
ECgene alternative splicing isoforms for
MAGEB16

Expression for MAGEB16 Gene

mRNA expression in normal human tissues for MAGEB16 Gene

mRNA differential expression in normal tissues according to GTEx for MAGEB16 Gene

This gene is overexpressed in Testis (x52.7).

Protein differential expression in normal tissues from HIPED for MAGEB16 Gene

This gene is overexpressed in Amniocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for MAGEB16 Gene



SOURCE GeneReport for Unigene cluster for MAGEB16 Gene Hs.700562

genes like me logo Genes that share expression patterns with MAGEB16: view

Protein tissue co-expression partners for MAGEB16 Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for MAGEB16 Gene

Orthologs for MAGEB16 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MAGEB16 Gene

Organism Taxonomy Gene Similarity Type Details
dog
(Canis familiaris)
Mammalia LOC100856762 35
  • 76.23 (n)
  • 64.14 (a)
MAGEB16 36
  • 46 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Mageb16 35
  • 67.52 (n)
  • 58.01 (a)
Mageb16 16
Mageb16 36
  • 48 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia MAGEB16 35
  • 98.46 (n)
  • 96.91 (a)
MAGEB16 36
  • 88 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mageb16 35
  • 64.66 (n)
  • 53.8 (a)
cow
(Bos Taurus)
Mammalia MAGEB16 36
  • 70 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 38 (a)
ManyToMany
-- 36
  • 24 (a)
ManyToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 30 (a)
OneToMany
chicken
(Gallus gallus)
Aves MAGE 36
  • 37 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 36
  • 38 (a)
OneToMany
zebrafish
(Danio rerio)
Actinopterygii ndnl2 36
  • 35 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 32 (a)
OneToMany
Species with no ortholog for MAGEB16:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MAGEB16 Gene

ENSEMBL:
Gene Tree for MAGEB16 (if available)
TreeFam:
Gene Tree for MAGEB16 (if available)

Paralogs for MAGEB16 Gene

Pseudogenes.org Pseudogenes for MAGEB16 Gene

genes like me logo Genes that share paralogs with MAGEB16: view

Variants for MAGEB16 Gene

Sequence variations from dbSNP and Humsavar for MAGEB16 Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs1410961 - 35,802,308(+) AGACC(C/T)TCCTC reference, missense
rs1410962 - 35,802,579(+) CAAGT(A/G)TCAGA reference, missense
rs5973488 - 35,802,678(+) TGAGC(A/G)CCTAG reference, missense
rs4829390 - 35,802,938(+) CCAGA(A/G)TGCTC reference, missense
rs4829391 - 35,802,939(+) CAGAA(A/T)GCTCA reference, missense

Structural Variations from Database of Genomic Variants (DGV) for MAGEB16 Gene

Variant ID Type Subtype PubMed ID
esv24451 CNV Loss 19812545

Variation tolerance for MAGEB16 Gene

Residual Variation Intolerance Score: 88.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.60; 12.96% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for MAGEB16 Gene

Disorders for MAGEB16 Gene

Relevant External Links for MAGEB16

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MAGEB16

No disorders were found for MAGEB16 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MAGEB16 Gene

Publications for MAGEB16 Gene

  1. The DNA sequence of the human X chromosome. (PMID: 15772651) Ross M.T. … Bentley D.R. (Nature 2005) 3 4 67
  2. An overview of the MAGE gene family with the identification of all human members of the family. (PMID: 11454705) Chomez P. … Lucas S. (Cancer Res. 2001) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. Demethylation of CpG islands in the 5' upstream regions mediates the expression of the human testis-specific gene MAGEB16 and its mouse homolog Mageb16. (PMID: 24219866) Liu Y. … Zhang S. (BMB Rep 2014) 3

Products for MAGEB16 Gene

Sources for MAGEB16 Gene

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