MAGEB16 Gene
protein-coding GIFtS: 34
GCID: GC0XP035816
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melanoma antigen family B, 16(Previous names: melanoma antigen family B, 16 (pseudogene) )
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Aliases
for MAGEB16 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Melanoma Antigen Family B, 161 2 | | Melanoma Antigen Family B, 16 (Pseudogene)1 2 | | MAGE-B16 Antigen2 3 | | Melanoma-Associated Antigen B162 |
Export aliases for MAGEB16 gene to outside databasesPrevious GC identifers: GC0XU900549 GC0XP035726 GC0XP033557 |
Summaries
for MAGEB16 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for MAGEB16 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000023.10 NC_018934.1 NT_167197.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MAGEB16 gene promoter:
C/EBPbeta Pax-2 IRF-1 Pax-2a C/EBPalpha POU2F1 Pax-2b POU2F1a PPAR-gamma2 LyF-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for MAGEB16
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAGEB16 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xp21.1 Ensembl cytogenetic band: Xp21.1 HGNC cytogenetic band: Xp21.1MAGEB16 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP035816: view genomic region
(about GC identifiers)
Start:
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35,816,459 bp from pter |
End:
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35,821,852 bp from pter |
Size:
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5,394 bases |
Orientation:
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plus strand |
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Proteins
for MAGEB16 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MAGBG_HUMAN, A2A368 (See
protein sequence)Recommended Name: Melanoma-associated antigen B16 Size: 324 amino acids; 36178 Da
Sequence caution: Sequence=CAM20853.1; Type=Erroneous gene model prediction;
Secondary accessions: A8MU30Explore the universe of human proteins at neXtProt for MAGEB16: NX_A2A368
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_A2A368
MAGEB16 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001093391.1
ENSEMBL proteins: ENSP00000382870 ENSP00000382874 ENSP00000382869 ENSP00000382871 ENSP00000382867
Human Recombinant Protein Products:
MAGEB16 Antibody Products:
Assay Products for MAGEB16: |
Protein
Domains /
Families
for MAGEB16 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MAGEB16 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry A2A368ProtoNet protein and cluster: A2A368 UniProtKB/Swiss-Prot: MAGBG_HUMAN, A2A368Similarity: Contains 1 MAGE domain |
Function
for MAGEB16 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAGEB16 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAGEB16
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for MAGEB16 | |  | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat MAGEB16 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAGEB16 |
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Pathways & Interactions
for MAGEB16 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MAGEB16
|
Drugs & Compounds
for MAGEB16 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MAGEB16
Search CenterWatch for drugs/clinical trials and news about MAGEB16 / MAGBG
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Transcripts
for MAGEB16 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MAGEB16 gene: NM_001099921.1 Unigene Cluster for MAGEB16: Melanoma antigen family B, 16 Hs.700562 Unigene Representative Sequence: NM_0010999215 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000399988 ENST00000399992 ENST00000399987 ENST00000399989(uc010ngt.1)
ENST00000399985
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAGEB16 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAGEB16
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MAGEB16 (NM_001099921) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MAGEB16 | | | Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat MAGEB16 |
GeneLoc Exon Structure
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Expression
for MAGEB16 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MAGEB16 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ACATTGCTAA
About this image
See MAGEB16 Protein Expression from SPIRE MOPED and PaxDB
SOURCE GeneReport for Unigene cluster: Hs.700562
SABiosciences Custom PCR Arrays for MAGEB16
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MAGEB16
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MAGEB16 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAGEB16 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAGEB16 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAGEB16 |
Orthologs
for MAGEB16 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
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This gene was present in the common ancestor of animals.
Orthologs for MAGEB16 gene from 3/17 species (see all 17) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
-- |
-- |
42(a) |
1 → many |
1(205669616-205678308) |
zebrafish
(Danio rerio) |
Actinopterygii |
ndnl26 |
necdin-like 2 |
35(a) |
1 → many |
23(13012414-13025121) |
fruit fly
(Drosophila melanogaster) |
Insecta |
MAGE6 |
MAGE |
25(a) |
1 → many |
3R(2979960-2980898) |
ENSEMBL Gene Tree for MAGEB16 (if available)
TreeFam Gene Tree for MAGEB16 (if available) |
Paralogs
for MAGEB16 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MAGEB16 gene
- MAGEC22 MAGEA9B2 MAGEB52 MAGEB42 MAGEB12 MAGEC12 MAGED42 MAGEA82
- MAGED22 MAGEA122 MAGEA92 MAGEB172 MAGEB102 MAGEA62 MAGEE12 MAGED12
- MAGEA22 MAGEC32 MAGEA32 NDN2 MAGEB22 MAGEB32 MAGED4B2 MAGEE22
- MAGEA42 MAGEA12 MAGEA102 MAGEB182 MAGEA2B2 MAGEB62 MAGEL22 TRO2
- MAGEA112 NDNL22 MAGEF12
18/36 SIMAP similar genes for MAGEB16 using alignment to 1 protein entry: MAGBG_HUMAN(see all similar genes):MAGEH1 MAGE-B1 MAGEA8 MAGEB1 MAGEB18 MAGEC1
NDNL2 MAGEB10 MAGEB4 MAGEB5 MAGEC2 MAGEC4
MAGEE1 MAGEA4 MAGEA10 MAGEA9B MAGEB2 MAGEA11
MAGEB16 for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for MAGEB16
PGOHUM00000241674 PGOHUM00000241699
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Genomic Variants
for MAGEB16 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr X pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
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HapMap Linkage Disequilibrium report for MAGEB16 (35816459 - 35821852 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for MAGEB16
1 CNV: 73956 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MAGEB16 |
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Disorders
/ Diseases
for MAGEB16 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MAGEB16 for disorders About GeneDecksing
OMIM gene information: 300762
OMIM disorders: --
1  disease for MAGEB16: About MalaCardsmelanoma
Export disorders for MAGEB16 gene to outside databases
|
Publications
for MAGEB16 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MAGEB16 gene integrated from 9 sources:
(articles sorted by number of sources associating them with MAGEB16) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
- An overview of the MAGE gene family with the identification of all human members of the family. (PubMed id 11454705)1, 3 Chomez P....Lucas S. (2001)
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External Searches for MAGEB16 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing MAGEB16 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
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Other Databases showing MAGEB16 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MAGEB16 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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About This Section
| Patent Information for MAGEB16 gene:
Search GeneIP for patents involving MAGEB16
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MAGEB16 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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 | | | MAGEB16 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAGEB16 |
|  |  |  | | | | Search ThermoFisher Antibodies for MAGEB16 |
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