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Aliases for MAGEA9B Gene

Aliases for MAGEA9B Gene

  • MAGE Family Member A9B 2 3 5
  • Melanoma Antigen Family A9B 2 3
  • Cancer/Testis Antigen 1.9 3 4
  • MAGE-9 Antigen 3 4
  • CT1.9 3 4
  • Melanoma Antigen Family A, 9B 3
  • MAGEA9 MAGEA9B 4
  • MAGEA9A 4
  • MAGE9 4

External Ids for MAGEA9B Gene

Previous GeneCards Identifiers for MAGEA9B Gene

  • GC0XM148471
  • GC00U922286
  • GC0XM148663

Summaries for MAGEA9B Gene

Entrez Gene Summary for MAGEA9B Gene

  • MAGEA9B is a duplication of the MAGEA9 gene (MIM 300342) on chromosome Xq28. The 2 copies are separated by about 194 kb (Hartz, 2009).[supplied by OMIM, Mar 2009]

GeneCards Summary for MAGEA9B Gene

MAGEA9B (MAGE Family Member A9B) is a Protein Coding gene. An important paralog of this gene is MAGEC3.

UniProtKB/Swiss-Prot for MAGEA9B Gene

  • Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MAGEA9B Gene

Genomics for MAGEA9B Gene

Regulatory Elements for MAGEA9B Gene

Genomic Location for MAGEA9B Gene

Chromosome:
X
Start:
149,581,651 bp from pter
End:
149,587,468 bp from pter
Size:
5,818 bases
Orientation:
Minus strand

Genomic View for MAGEA9B Gene

Genes around MAGEA9B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MAGEA9B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MAGEA9B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MAGEA9B Gene

Proteins for MAGEA9B Gene

  • Protein details for MAGEA9B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P43362-MAGA9_HUMAN
    Recommended name:
    Melanoma-associated antigen 9
    Protein Accession:
    P43362
    Secondary Accessions:
    • A8K8A7
    • Q7Z5K4
    • Q92910

    Protein attributes for MAGEA9B Gene

    Size:
    315 amino acids
    Molecular mass:
    35088 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MAGEA9B Gene

Proteomics data for MAGEA9B Gene at MOPED

Post-translational modifications for MAGEA9B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MAGEA9B Gene

No data available for DME Specific Peptides for MAGEA9B Gene

Domains & Families for MAGEA9B Gene

Gene Families for MAGEA9B Gene

Protein Domains for MAGEA9B Gene

InterPro:
Blocks:
ProtoNet:

Suggested Antigen Peptide Sequences for MAGEA9B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

P43362

UniProtKB/Swiss-Prot:

MAGA9_HUMAN :
  • Contains 1 MAGE domain.
Domain:
  • Contains 1 MAGE domain.
genes like me logo Genes that share domains with MAGEA9B: view

Function for MAGEA9B Gene

Molecular function for MAGEA9B Gene

UniProtKB/Swiss-Prot Function:
Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor progression.

Phenotypes for MAGEA9B Gene

genes like me logo Genes that share phenotypes with MAGEA9B: view

Animal Model Products

CRISPR Products

miRNA for MAGEA9B Gene

miRTarBase miRNAs that target MAGEA9B

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MAGEA9B Gene

Localization for MAGEA9B Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MAGEA9B Gene

Pathways & Interactions for MAGEA9B Gene

SuperPathways for MAGEA9B Gene

No Data Available

Interacting Proteins for MAGEA9B Gene

Selected Interacting proteins: P43362-MAGA9_HUMAN for MAGEA9B Gene via UniProtKB

Symbol External ID(s) Details
APPL1

Gene Ontology (GO) - Biological Process for MAGEA9B Gene

None

No data available for Pathways by source and SIGNOR curated interactions for MAGEA9B Gene

Drugs & Compounds for MAGEA9B Gene

No Compound Related Data Available

Transcripts for MAGEA9B Gene

mRNA/cDNA for MAGEA9B Gene

(3) REFSEQ mRNAs :
(5) Additional mRNA sequences :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MAGEA9B Gene

Melanoma antigen family A, 9B:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MAGEA9B Gene

No ASD Table

Relevant External Links for MAGEA9B Gene

GeneLoc Exon Structure for
MAGEA9B
ECgene alternative splicing isoforms for
MAGEA9B

Expression for MAGEA9B Gene

mRNA expression in normal human tissues for MAGEA9B Gene

Protein differential expression in normal tissues from HIPED for MAGEA9B Gene

This gene is overexpressed in Ovary (61.7) and Testis (7.3).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for MAGEA9B Gene



SOURCE GeneReport for Unigene cluster for MAGEA9B Gene Hs.460974

mRNA Expression by UniProt/SwissProt for MAGEA9B Gene

P43362-MAGA9_HUMAN
Tissue specificity: Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta.
genes like me logo Genes that share expression patterns with MAGEA9B: view

Protein tissue co-expression partners for MAGEA9B Gene

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA differential expression in normal tissues for MAGEA9B Gene

Orthologs for MAGEA9B Gene

Evolution for MAGEA9B Gene

ENSEMBL:
Gene Tree for MAGEA9B (if available)
TreeFam:
Gene Tree for MAGEA9B (if available)

No data available for Orthologs for MAGEA9B Gene

Paralogs for MAGEA9B Gene

genes like me logo Genes that share paralogs with MAGEA9B: view

Variants for MAGEA9B Gene

Sequence variations from dbSNP and Humsavar for MAGEA9B Gene

SNP ID Clin Chr 0X pos Sequence Context AA Info Type
rs150704666 -- 149,583,706(+) CAAGA(C/G)GGCGG intron-variant
rs375905323 -- 149,586,564(+) GGGGG(C/G)GGTGA intron-variant
rs200294165 -- 149,588,813(+) ATGGG(G/T)TTTTT upstream-variant-2KB
rs201969621 -- 149,587,383(+) GCCTC(A/G)GCCAG intron-variant, upstream-variant-2KB
rs202146513 -- 149,583,088(+) CTGTG(G/T)GTTCC reference, missense

Structural Variations from Database of Genomic Variants (DGV) for MAGEA9B Gene

Variant ID Type Subtype PubMed ID
nsv525908 CNV Gain 19592680
nsv518742 CNV Gain 19592680
nsv508809 CNV Insertion 20534489
nsv818041 CNV Gain 17921354

Variation tolerance for MAGEA9B Gene

Gene Damage Index Score: 0.00; 0.01% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MAGEA9B Gene

HapMap Linkage Disequilibrium report
MAGEA9B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MAGEA9B Gene

Disorders for MAGEA9B Gene

Relevant External Links for MAGEA9B

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
MAGEA9B

No disorders were found for MAGEA9B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MAGEA9B Gene

Publications for MAGEA9B Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3

Products for MAGEA9B Gene

Sources for MAGEA9B Gene

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