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Aliases &
Descriptions
for MAGEA9B
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases |
|---|
| CT1.9 3 | | MAGE9 3 | | MAGEA9A 3 | | OTTHUMP00000024211 2 |
| | | Descriptions |
|---|
| Cancer/testis antigen 1.9 3 | | MAGE-9 antigen 3 | | melanoma antigen family A, 9 -like 2 | | melanoma antigen family A, 9B 2 |
|
| |
Search outside databases for aliases for MAGEA9B genePrevious GC identifer: GC00U922286 |
Summaries
for MAGEA9B(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| EntrezGene summary for MAGEA9B:
MAGEA9B is a duplication of the MAGEA9 gene (MIM 300342) on chromosome Xq28. The 2 copies are
separated by about 194 kb (Hartz, 2009).[supplied by OMIM]
UniProtKB/Swiss-Prot: MAGA9_HUMAN, P43362Function: Not known, though may play a role in embryonal development and tumor transformation or
aspects of tumor progression |
Genomic Location
for MAGEA9B
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences)
About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: Xq28 Ensembl cytogenetic band: Xq28 HGNC cytogenetic band: Xp11MAGEA9B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM148471:
(about GC identifiers)
Start:
|
148,471,105 bp from pter |
End:
|
148,476,911 bp from pter |
Size:
|
5,807 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000023.9 NT_011681.15
| Proteins
for MAGEA9B
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: MAGA9_HUMAN, P43362 (See
protein sequence)Recommended Name: Melanoma-associated antigen 9 Size: 315 amino acids; 35088 Da
Secondary accessions: A8K8A7 Q7Z5K4 Q92910REFSEQ proteins: NP_001074259.1
ENSEMBL proteins: ENSP00000243314
Human Recombinant Proteins  Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 
1 Gene Ontology (GO) cellular component term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005575 | cellular_component |
ND | -- |
About this table
Antibodies for MAGEA9B:
Assays for MAGEA9B: | Protein
Domains/
Families
for MAGEA9B(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry P43362
ProtoNet protein and cluster: P43362 1 Blocks protein family: IPB002190 MAGE protein
UniProtKB/Swiss-Prot: MAGA9_HUMAN, P43362Similarity: Contains 1 MAGE domain | Gene Function
for MAGEA9B
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| Browse Origene for 29mer shRNA kit in GFP-retroviral vector
 Applied Biosystems Silencer® siRNAs for MAGEA9B
 Sigma-Aldrich siRNA for MAGEA9B
Browse shRNA at Sigma-Aldrich
Explore Sigma-Aldrich super-pooled esiRNAs
OriGene GFP tagged cDNA clone in CMV expression vector: NM_001080790
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001080790
untagged cDNA clone in CMV expression vector: NM_001080790
Primers:  Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
OriGene genome-wide validated SYBR primer pairs: NM_001080790
UniProtKB/Swiss-Prot: MAGA9_HUMAN, P43362Function: Not known, though may play a role in embryonal development and tumor transformation or
aspects of tumor progression1 Gene Ontology (GO) molecular function term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- |
About this table | Pathways & Interactions
for MAGEA9B
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
--1 Gene Ontology (GO) biological process term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008150 | biological_process |
ND | -- |
About this table
|
Drugs & Compounds
for MAGEA9B(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for MAGEA9B
|
Transcripts
for MAGEA9B(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene,
Expression Assays from Applied Biosystems)
About This Section
| Browse Origene for 29mer shRNA kit in GFP-retroviral vector
Sigma-Aldrich siRNA for MAGEA9B
Browse shRNA at Sigma-Aldrich
Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer® siRNAs: NM_001080790 REFSEQ mRNAs for MAGEA9B gene: NM_001080790.1
Applied Biosystems TaqMan ® Gene Expression Assays: NM_001080790
OriGene GFP tagged cDNA clone in CMV expression vector: NM_001080790
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001080790
untagged cDNA clone in CMV expression vector: NM_001080790
Additional cDNA sequence: AK292272.1 AK313321.1 AY310325.1 BC002351.2 BC098100.1 2 DOTS entries: DT.92418006 DT.121317502 Unigene Cluster for MAGEA9B: Melanoma antigen family A, 9B Hs.460974 [show with all ESTs]Unigene Representative Sequence: BC002351
GeneLoc Exon Structure
1 Ensembl transcript including schematic representation: ENST00000243314
|
Expression
for MAGEA9B
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| MAGEA9B expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for MAGEA9B
1 / 2 3 probe-sets matching MAGEA9B gene Data from
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.460974
UniProtKB/Swiss-Prot: MAGA9_HUMAN, P43362Tissue specificity: Expressed in many tumors of several types, such as melanoma, head and neck
squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for
testes and placenta |
Orthologs
for MAGEA9B
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for MAGEA9B gene from 3 species
About this table Species with no ortholog for MAGEA9B
ENSEMBL Gene Tree for MAGEA9B | Paralogs
for MAGEA9B(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for MAGEA9B gene
- MAGEA91 2 MAGEA32 MAGEA2B2 MAGEA82 MAGEA122 MAGEA42 MAGEA112 MAGEA12
- MAGEA102 MAGEA62 MAGEA22
|
SNPs/Variants
for MAGEA9B(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
| -- |
Disorders & Mutations
for MAGEA9B
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 300764
|
Medical News
for MAGEA9B(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for MAGEA9B (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 7 PubMed articles for MAGEA9B gene:- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)3, 4 Gerhard D.S....Malek J. (2004)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)3, 4 Ota T....Sugano S. (2004)
- Molecular and phenotypic variation in patients with severe Hunter syndrome. (PubMed id 9147653)3, 4 Timms K.M....Gibbs R.A. (1997)
- Structure, chromosomal localization, and expression of 12 genes of the MAGE family. (PubMed id 7927540)3, 4 De Plaen E.... Boon T. (1994)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)3 Kimura K.... Sugano S. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)3 Strausberg R.L....Marra M.A. (2002)
- The melanoma antigen gene (MAGE) family is clustered in the chromosomal band Xq28. (PubMed id 8575766)3 Rogner U.C....Poustka A. (1995)
|
Search for MAGEA9B
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MAGEA9B
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing MAGEA9B
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MAGEA9B(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| About This Section
| --
| Services
for MAGEA9B(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section
| 
Products for MAGEA9B:
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