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Aliases &
Descriptions
for MAGEA5
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases |
|---|
| CT1.5 1, 2, 3 | | MAGE5 2, 3, 5 | | MAGEA4 2 | | MGC129526 1, 2 |
| | | Descriptions |
|---|
| Cancer/testis antigen 1.5 3 | | MAGE-5 antigen 3 | | MAGE-5a antigen 2 | | MAGE-5b antigen 2 | | cancer/testis antigen family 1, member 5 2 | | melanoma antigen family A, 5 2 |
|
| |
Search outside databases for aliases for MAGEA5 genePrevious GC identifers: GC0XM145618 GC0XM147941 GC0XM149030 GC0XM149900 GC0XM150953 |
Summaries
for MAGEA5(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| EntrezGene summary for MAGEA5:
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50
to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show
considerable variability, suggesting that the existence of this gene family enables the same
function to be expressed under different transcriptional controls. The MAGEA genes are clustered
at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as
dyskeratosis congenita. [provided by RefSeq]
UniProtKB/Swiss-Prot: MAGA5_HUMAN, P43359Function: Not known, though may play a role tumor transformation or progression |
Genomic Location
for MAGEA5
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences)
About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
 Transcription factor binding sites upstream to the MAGEA5 gene 
Entrez Gene cytogenetic band: Xq28 Ensembl cytogenetic band: Xq28 HGNC cytogenetic band: Xq28MAGEA5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome X GeneLoc Exon Structure GeneLoc location for GC0XM151033:
(about GC identifiers)
Start:
|
151,033,182 bp from pter |
End:
|
151,037,100 bp from pter |
Size:
|
3,919 bases |
Orientation:
|
minus strand |
RefSeq DNA sequence:- NC_000023.9 NT_011726.13
| Proteins
for MAGEA5
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: MAGA5_HUMAN, P43359 (See
protein sequence)Recommended Name: Melanoma-associated antigen 5 Size: 124 amino acids; 13016 Da
Secondary accessions: Q32MD0REFSEQ proteins: NP_066387.1
ENSEMBL proteins: ENSP00000327762
Human Recombinant Proteins  Browse Origene for full length recombinant human proteins expressed in human HEK293 cells
1 Gene Ontology (GO) cellular component term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005575 | cellular_component |
ND | -- |
About this table
Antibodies for MAGEA5:
Assays for MAGEA5: | Protein
Domains/
Families
for MAGEA5(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry P43359
ProtoNet protein and cluster: P43359 UniProtKB/Swiss-Prot: MAGA5_HUMAN, P43359Similarity: Contains 1 MAGE domain | Gene Function
for MAGEA5
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_021049
 Applied Biosystems Silencer® siRNAs for MAGEA5
 Sigma-Aldrich siRNA for MAGEA5
Sigma-Aldrich shRNA for MAGEA5
Explore Sigma-Aldrich super-pooled esiRNAs
OriGene GFP tagged cDNA clone in CMV expression vector: NM_021049
Myc/DDK tagged cDNA clone in CMV expression vector: NM_021049
untagged cDNA clone in CMV expression vector: NM_021049
Primers:  Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
OriGene genome-wide validated SYBR primer pairs: NM_021049
UniProtKB/Swiss-Prot: MAGA5_HUMAN, P43359Function: Not known, though may play a role tumor transformation or progressionGenatlas biochemistry entry for MAGEA5:human melanoma antigen,family A,member 5,expressed in melanoma,testis1 Gene Ontology (GO) molecular function term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003674 | molecular_function |
ND | -- |
About this table | Pathways & Interactions
for MAGEA5
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
--1 Gene Ontology (GO) biological process term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008150 | biological_process |
ND | -- |
About this table
|
Drugs & Compounds
for MAGEA5(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for MAGEA5
|
Transcripts
for MAGEA5(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene,
Expression Assays from Applied Biosystems)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_021049
Sigma-Aldrich siRNA for MAGEA5
Sigma-Aldrich shRNA for MAGEA5
Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer® siRNAs: NM_021049 REFSEQ mRNAs for MAGEA5 gene: NM_021049.3
Applied Biosystems TaqMan ® Gene Expression Assays: NM_021049
OriGene GFP tagged cDNA clone in CMV expression vector: NM_021049
Myc/DDK tagged cDNA clone in CMV expression vector: NM_021049
untagged cDNA clone in CMV expression vector: NM_021049
Additional cDNA sequence: AY310324.1 BC109187.1 1 DOTS entry: DT.95103326 24/48 AceView cDNA sequences (see all 48
):BG477105 BE277360 CR622868 BG477980 BQ217649 BX335540 CB158974 BG477436 AI142010 BX109673 AY531264 BU167137 BG282169 BX335541 BG478664 BX097006 BG478456 NM_021049 AY310324 BE277068 BC004105 CD109866 BE389926 R23725
 highest scoring ESTs for MAGEA5:U10689 AI200443 NM_021049 BC109187 Unigene Cluster for MAGEA5: Melanoma antigen family A, 5 Hs.668021 Unigene Representative Sequence: NM_021049
GeneLoc Exon Structure
1 Ensembl transcript including schematic representation: ENST00000345830
|
Expression
for MAGEA5
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| MAGEA5 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for MAGEA5
1 / 2 / 3 4 probe-sets matching MAGEA5 gene Data from
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.668021
Expression variation in blood from EXPOLDB for MAGEA5 UniProtKB/Swiss-Prot: MAGA5_HUMAN, P43359Tissue specificity: Expressed in many tumors of several types, such as melanoma, head and neck
squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for
testes |
Orthologs
for MAGEA5
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
| ENSEMBL Gene Tree for MAGEA5 | Paralogs
for MAGEA5(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| -- |
SNPs/Variants
for MAGEA5(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for MAGEA5 (up to first 250kb)
|
Disorders & Mutations
for MAGEA5
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
|
OMIM: 300340
|
Medical News
for MAGEA5(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for MAGEA5 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 7 PubMed articles for MAGEA5 gene:- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)3, 4 Gerhard D.S....Malek J. (2004)
- The melanoma antigen gene (MAGE) family is clustered in the chromosomal band Xq28. (PubMed id 8575766)2, 3 Rogner U.C....Poustka A. (1995)
- Structure, chromosomal localization, and expression of 12 genes of the MAGE family. (PubMed id 7927540)3, 4 De Plaen E.... Boon T. (1994)
- Expression of melanoma-associated antigens in oral squamous cell carcinoma. (PubMed id 18197853)3 Ries J....Nkenke E. (2008)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)3 Strausberg R.L....Marra M.A. (2002)
- Identification, expression, and nuclear location of murine Mage-b2 protein, a tumor-associated antigen. (PubMed id 11211869)3 Lee J.H....Park J.H. (2000)
- Quantitative evaluation of the expression of MAGE genes in tumors by limiting dilution of cDNA libraries. (PubMed id 10521804)3 Serrano A....Boon T. (1999)
|
Search for MAGEA5
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MAGEA5
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing MAGEA5
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MAGEA5(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| About This Section
| --
| Services
for MAGEA5(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section
| 
Products for MAGEA5:
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