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MAGEA3 Gene

protein-coding   GIFtS: 55
GCID: GC0XM151934

Melanoma Antigen Family A, 3


(Previous symbol: MAGE3)
  See MAGEA3-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Melanoma Antigen Family A, 31 2     Cancer/Testis Antigen Family 11
MAGE31 2 3 5     Member 31
MAGE-3 Antigen1 2 3     HIP82
Antigen MZ2-D1 2 3     HYPD2
Melanoma-Associated Antigen 31 2     MAGEA62
Cancer/Testis Antigen 1.32 3     Cancer/Testis Antigen Family 1, Member 32
CT1.32 3     

External Ids:    HGNC: 68011   Entrez Gene: 41022   Ensembl: ENSG000002218677   OMIM: 3001745   UniProtKB: P433573   

Export aliases for MAGEA3 gene to outside databases

Previous GC identifers: GC0XM146274 GC0XM148591 GC0XM149682 GC0XM150552 GC0XM151605 GC0XM151685 GC0XM140736


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for MAGEA3 Gene:
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence
identity to each other. The promoters and first exons of the MAGEA genes show considerable variability,
suggesting that the existence of this gene family enables the same function to be expressed under different
transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated
in some hereditary disorders, such as dyskeratosis congenita. (provided by RefSeq, Jul 2008)

GeneCards Summary for MAGEA3 Gene:
MAGEA3 (melanoma antigen family A, 3) is a protein-coding gene. Diseases associated with MAGEA3 include cholangiocarcinoma, and melanoma. An important paralog of this gene is MAGEC2.

UniProtKB/Swiss-Prot: MAGA3_HUMAN, P43357
Function: Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein
ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28.
Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate
complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In
vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic
T-lymphocytes

Gene Wiki entry for MAGEA3 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000023.10  NT_011681.17  NC_018934.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the MAGEA3 gene promoter:
         MEF-2A   p53   FOXJ2 (long isoform)   MEF-2   MyoD   FOXJ2   aMEF-2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for MAGEA3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MAGEA3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq28   Ensembl cytogenetic band:  Xq28   HGNC cytogenetic band: Xq28

MAGEA3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MAGEA3 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM151934:  view genomic region     (about GC identifiers)

Start:
151,934,652 bp from pter      End:
151,938,240 bp from pter
Size:
3,589 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: MAGA3_HUMAN, P43357 (See protein sequence)
Recommended Name: Melanoma-associated antigen 3  
Size: 314 amino acids; 34747 Da
Subunit: Interacts with TRIM28
Caution: In vitro experiments by PubMed:17942928 measuring cell viability in melanoma cell lines used siRNA
specific for MAGEA3 and MAGEA6
1 PDB 3D structure from and Proteopedia for MAGEA3:
1QEW (3D)    
Secondary accessions: Q6FHI6

Explore the universe of human proteins at neXtProt for MAGEA3: NX_P43357

Explore proteomics data for MAGEA3 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See MAGEA3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_005353.1  
    ENSEMBL proteins: 
     ENSP00000359301   ENSP00000392758   ENSP00000377480  

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    antibodies-online proteins for MAGEA3 (10 products) 

     
    antibodies-online peptides for MAGEA3

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR021072 Melanoma_ass_antigen_N
     IPR002190 MAGE

    Graphical View of Domain Structure for InterPro Entry P43357

    ProtoNet protein and cluster: P43357

    1 Blocks protein domain: IPB002190 MAGE protein

    UniProtKB/Swiss-Prot: MAGA3_HUMAN, P43357
    Similarity: Contains 1 MAGE domain


    Find genes that share domains with MAGEA3           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MAGA3_HUMAN, P43357
    Function: Proposed to enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein
    ligases. May enhance ubiquitin ligase activity of TRIM28 and stimulate p53/TP53 ubiquitination by TRIM28.
    Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate
    complex. May play a role in embryonal development and tumor transformation or aspects of tumor progression. In
    vitro promotes cell viability in melanoma cell lines. Antigen recognized on a melanoma by autologous cytolytic
    T-lymphocytes

         Genatlas biochemistry entry for MAGEA3:
    human melanoma antigen,family A,member 3,expressed in melanoma,testis,advanced gastric carcinomas and
    hepatocellular carcinomas

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
         
    Find genes that share ontologies with MAGEA3           About GenesLikeMe


    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for MAGEA3

    miRNA
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    miRTarBase miRNAs that target MAGEA3:
    hsa-mir-34a-5p (MIRT004111)

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    nucleus1
    peroxisome1
    plasma membrane1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MAGEA3
    Interactions:

        Search GeneGlobe Interaction Network for MAGEA3

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for MAGEA3 (P433571, 3 ENSP000003593014) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    HTTP428583, ENSP000003471844I2D: score=1 STRING: ENSP00000347184
    TRIM28Q132631, ENSP000002530244EBI-5651459,EBI-78139 STRING: ENSP00000253024
    SUMO2ENSP000004059654STRING: ENSP00000405965
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MAGEA3 (MAGA3)

    4 Novoseek inferred chemical compound relationships for MAGEA3 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    hemocyanin 53.5 2 10431688 (1), 11522640 (1)
    ethidium bromide 11.2 1 15570431 (1)
    paraffin 6.12 2 11776642 (1), 15100734 (1)
    oligonucleotide 0 1 15355897 (1)



    Find genes that share compounds with MAGEA3           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for MAGEA3 gene: 
    NM_005362.3  

    Unigene Cluster for MAGEA3:

    Melanoma antigen family A, 3
    Hs.417816  [show with all ESTs]
    Unigene Representative Sequence: NM_005362
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000370278(uc004fgp.3) ENST00000417212 ENST00000393902
    miRNA
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      QuantiTect SYBR Green Assays in human, mouse, rat MAGEA3
      QuantiFast Probe-based Assays in human, mouse, rat MAGEA3

    Additional mRNA sequence: 

    AK223519.1 AK292384.1 BC000340.2 BC005963.1 BC011744.2 BC016803.1 BC017389.1 CR541767.1 
    CR541768.1 CR541774.1 CR542020.1 

    3 DOTS entries:

    DT.91772022  DT.208961  DT.100777807 

    Selected AceView cDNA sequences (see all 183):

    BI090658 BC063681 BE279401 NM_175742 BX106621 BM549169 BF219695 NM_175743 
    BC005963 CA441190 BF791772 BC000340 CB145878 BM479202 AW673548 BG575302 
    CA415709 CD557117 BQ226610 NM_005362 BM449726 BC017389 BQ436888 BE901056 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    MAGEA3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGATAACTCA
    MAGEA3 Expression
    About this image


    MAGEA3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Testis (Reproductive System)
             Spermatogonium Type B Seminiferous Tubules
     
     Gonad
             Spermatogonium Type B Seminiferous Tubules
    MAGEA3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    MAGEA3 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.417816

    UniProtKB/Swiss-Prot: MAGA3_HUMAN, P43357
    Tissue specificity: Expressed in many tumors of several types, such as melanoma, head and neck squamous cell
    carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes and placenta. Never
    expressed in kidney tumors, Leukemias and lymphomas

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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      --

    ENSEMBL Gene Tree for MAGEA3 (if available)
    TreeFam Gene Tree for MAGEA3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for MAGEA3 gene
    MAGEA61 2  MAGEC22  MAGEA9B2  MAGEB52  MAGEB162  MAGEB12  MAGEB42  MAGEC12  
    MAGED42  MAGEA82  MAGED22  MAGEA122  MAGEA92  MAGEB172  MAGEB102  MAGED12  
    MAGEA22  MAGEB22  NDN2  MAGEB32  MAGED4B2  MAGEA42  MAGEA12  MAGEA102  
    MAGEB182  MAGEA2B2  MAGEB62  MAGEL22  TRO2  MAGEA112  NDNL22  MAGEF12  
    Selected SIMAP similar genes for MAGEA3 using alignment to 2 protein entries:     MAGA3_HUMAN (see all proteins) (see all similar genes):
    MAGEA6    MAGEA12    MAGEA2B    MAGEA2    MAGEA5    MAGEA4
    MAGEA8    MAGEA11    MAGEA1    MAGEA9B    MAGEA9    MAGEC4
    MAGEH1    TRO    MAGEC3    MAGED4    MAGED4B    MAGEB16

    Find genes that share paralogs with MAGEA3           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for MAGEA3 (see all 68)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1475063031,2
    --151934848(+) CTTTTA/TCCACT 2 -- ut310--------
    rs1385581711,2
    --151934851(+) TTACCA/GCTGCT 2 -- ut310--------
    rs617500341,2
    C--151935240(+) TCTCTC/AAAAAC 4 /L /F mis11Minor allele frequency- A:0.01NS 78
    rs357809741,2
    C,F--151935244(-) GTGGGT/CTTTGA 4 /A /V mis12Minor allele frequency- C:0.00NS NA 4622
    rs1461269491,2
    C,F--151935272(+) GGAAAT/CGTGAG 4 /I /V mis11Minor allele frequency- C:0.00NA 4546
    rs359874571,2
    C,F--151935274(-) ACCTCA/GCATTT 4 H R mis11Minor allele frequency- G:0.00NA 4546
    rs617518911,2
    C,F--151935288(+) CCACTG/AATCTT 4 /I syn12Minor allele frequency- A:0.01NS NA 4624
    rs359831181,2
    C,F--151935332(-) CCCTCG/ATTGAA 4 /I /V mis12Minor allele frequency- A:0.00NA 4548
    rs1405947491,2
    C,F--151935335(+) AACGAG/TGGCCC 4 I L mis11Minor allele frequency- T:0.00NA 4546
    rs1412710771,2
    C,F--151935370(+) ATGCAG/AGATCA 4 /P /L mis11Minor allele frequency- A:0.00NA 4546

    HapMap Linkage Disequilibrium report for MAGEA3 (151934652 - 151938240 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for MAGEA3:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv2493e1CNV Complex17122850

    Locus Specific Mutation Databases (LSDB): MAGEA3

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 300174    OMIM disorders: --

    5 diseases for MAGEA3:    
    About MalaCards
    cholangiocarcinoma    melanoma    influenza    hepatocellular carcinoma
    lung cancer

    2 diseases from the University of Copenhagen DISEASES database for MAGEA3:
    Melanoma     Lung cancer

    Find genes that share disorders with MAGEA3           About GenesLikeMe

    Selected Novoseek inferred disease relationships for MAGEA3 gene (see all 35)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    melanoma 81.8 90 15570431 (3), 10546159 (3), 7805731 (2), 15305155 (2) (see all 61)
    metastatic melanoma 75.8 17 15945101 (2), 12973032 (1), 9935203 (1), 11511319 (1) (see all 12)
    testicular cancer 70.4 3 14991579 (1), 12855658 (1), 12681059 (1)
    tumors 60.5 125 15570431 (4), 18505125 (4), 8900375 (4), 7805731 (3) (see all 67)
    hepatocellular carcinoma 48.1 22 19260505 (4), 10961717 (3), 16806006 (2), 11857021 (1) (see all 11)
    cancer 47.6 22 17007017 (3), 9815643 (2), 11329779 (2), 7805731 (1) (see all 16)
    ocular melanoma 42.9 2 9220316 (2)
    metastasis 42.2 10 15570431 (2), 11857021 (1), 15305155 (1), 15657294 (1) (see all 8)
    bile duct cancer 41.3 1 10873083 (1)
    gastric carcinoma 35.7 6 9854470 (3), 7557134 (2), 10431688 (1)


    Export disorders for MAGEA3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for MAGEA3 gene, integrated from 10 sources (see all 232):
    (articles sorted by number of sources associating them with MAGEA3)
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    1. Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes. (PubMed id 8113684)1, 2, 9 Gaugler B.... Boon T. (J. Exp. Med. 1994)
    2. Cloning and analysis of MAGE-1-related genes. (PubMed id 8037761)1, 2, 9 Ding M.... Fenton R.G. (Biochem. Biophys. Res. Commun. 1994)
    3. MAGE-RING protein complexes comprise a family of E3 ubiquitin ligases. (PubMed id 20864041)1, 2 Doyle J.M.... Potts P.R. (Mol. Cell 2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Comparative genome sequence analysis of the Bpa/Str region in mouse and man. (PubMed id 10854409)1, 2 Mallon A.-M....Brown S.D.M. (Genome Res. 2000)
    6. The melanoma antigen gene (MAGE) family is clustered in the chromosomal band Xq28. (PubMed id 8575766)1, 3 Rogner U.C....Poustka A. (Genomics 1995)
    7. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. (PubMed id 1840703)1, 3 van der Bruggen P.... Boon T. (Science 1991)
    8. Fibroblast growth factor 2 and estrogen control the balance of histone 3 modifications targeting MAGE-A3 in pituitary neoplasia. (PubMed id 18381936)1, 9 Zhu X....Ezzat S. (Clin. Cancer Res. 2008)
    9. Promoter hypomethylation and reactivation of MAGE-A1 and MAGE-A3 genes in colorectal cancer cell lines and cancer tissues. (PubMed id 17007017)1, 9 Kim K.H....Park J.G. (World J. Gastroenterol. 2006)
    10. [Expression of melanoma antigen-1, 3 genes in human intrahepatic cholangiocarcinoma and its clinical significance]. (PubMed id 18505125)1, 9 Lu X....Huang J.F. (Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2008)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 4102 HGNC: 6801 AceView: MAGEA2andMAGEA3andMAGEA12 Ensembl:ENSG00000221867 euGenes: HUgn4102
    ECgene: MAGEA3 H-InvDB: MAGEA3

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for MAGEA3 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for MAGEA3 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
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    IP news from LifeMap Sciences, Inc.)
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    Patent Information for MAGEA3 gene:
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