MAGEA2 Gene

Aliases &
Descriptions
for MAGEA2

Previous GC identifers: GC0XP146223 GC0XP148540 GC0XM149666 GC0XM150536 GC0XM151588

Summaries
for MAGEA2

Gene Wiki entry for MAGEA2

Genomic Location
for MAGEA2

Proteins
for MAGEA2

Protein Domains/
Families
for MAGEA2

1 InterPro domain/family:

IPR002190 MAGE    GeneDecks  MAGEA2 for the domains selected above   About GeneDecksing

Graphical View of Domain Structure for InterPro Entry P43356

ProtoNet protein and cluster: P43356

Gene Function
for MAGEA2

Pathways & Interactions
for MAGEA2

Drugs & Compounds
for MAGEA2

Transcripts
for MAGEA2

Inhib. RNA:		Browse Invitrogen for RNAi
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (MAGEA2)

Applied Biosystems Silencer® siRNAs: 

REFSEQ mRNAs for MAGEA2 gene (3 alternative transcripts): 

Applied Biosystems TaqMan ® Gene Expression Assays: 

Expression
for MAGEA2

MAGEA2 expression in normal and diseased human tissues

 Applied Biosystems TaqMan ® Gene Expression Assays for MAGEA2

¹ / ² / ³

4 probe-sets matching MAGEA2 gene

	Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
			# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
	33518_f_at2, 3	U95-A	10	1.00	0.30	1.00	1.00	L18920	0.20	0.50	0.38	1
	214603_at2	U133-A	2	1.00	0.50	--	--	--	--	--	--	--
	1553830_s_at2	U133Plus2	2	1.00	0.50	--	--	--	--	--	--	--
	214603_at2	U133Plus2	2	1.00	0.50	--	--	--	--	--	--	--

About this table

GNF BioGPS
    About these images
About these images

CGAP SAGE TAG: ATACAAGGAA

SOURCE GeneReport for Unigene cluster: Hs.534597

UniProtKB/Swiss-Prot: MAGA2_HUMAN, P43356

Tissue specificity: Expressed in many tumors of several types, such as melanoma, head and neck

squamous cell carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for

testes

Orthologs
for MAGEA2

Paralogs
for MAGEA2

Paralogs for MAGEA2 gene

MAGEA2B^1 2  MAGEA3²  MAGEA8²  MAGEA12²  MAGEA9²  MAGEA9B²  MAGEA4²  MAGEA11²  

MAGEA1²  MAGEA10²  MAGEA6²  

SNPs/Variants
for MAGEA2

Disorders & Mutations
for MAGEA2

Medical News
for MAGEA2

Publications
for MAGEA2

• The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
• Comparative genome sequence analysis of the Bpa/Str region in mouse and Man. (PubMed id 10854409)^{3, 4} Mallon A.M....Brown S.D. (2000)
• The melanoma antigen gene (MAGE) family is clustered in the chromosomal band Xq28. (PubMed id 8575766)^{2, 3} Rogner U.C....Poustka A. (1995)
• Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes. (PubMed id 8113684)^{3, 4} Gaugler B.... Boon T. (1994)
• Sequence and expression pattern of the human MAGE2 gene. (PubMed id 8276455)^{3, 4} De Smet C....Boon T. (1994)
• A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. (PubMed id 1840703)^{2, 3} van der Bruggen P.... Boon T. (1991)
• Expression of melanoma-associated antigens in oral squamous cell carcinoma. (PubMed id 18197853)³ Ries J....Nkenke E. (2008)
• Methyl-CpG binding domain proteins and their involvement in the regulation of the MAGE-A1, MAGE-A2, MAGE-A3, and MAGE-A12 gene promoters. (PubMed id 17634428)³ Wischnewski F....Schwarzenbach H. (2007)
• MAGE-A tumor antigens target p53 transactivation function through histone deacetylase recruitment and confer resistance to chemotherapeutic agents. (PubMed id 16847267)³ Monte M....Schneider C. (2006)
• MAGE-A4 interacts with the liver oncoprotein gankyrin and suppresses its tumorigenic activity. (PubMed id 12525503)³ Nagao T....Fujita J. (2003)

Search for MAGEA2

Genome Databases showing MAGEA2

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Services
for MAGEA2