Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MAGEA10 Gene

protein-coding   GIFtS: 51
GCID: GC0XM151302

Melanoma Antigen Family A, 10


(Previous symbol: MAGE10)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Melanoma Antigen Family A, 101 2     CT1.102 3
MAGE101 2 3 5     Cancer/Testis Antigen Family 11
MAGE-10 Antigen1 2 3     Member 101
Melanoma-Associated Antigen 101 2     Cancer/Testis Antigen Family 1, Member 102
Cancer/Testis Antigen 1.102 3     

External Ids:    HGNC: 67971   Entrez Gene: 41092   Ensembl: ENSG000001242607   OMIM: 3003435   UniProtKB: P433633   

Export aliases for MAGEA10 gene to outside databases

Previous GC identifers: GC0XM145637 GC0XM147960 GC0XM149050 GC0XM149920 GC0XM150973 GC0XM151052 GC0XM140156


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MAGEA10 Gene:
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence
identity to each other. The promoters and first exons of the MAGEA genes show considerable variability,
suggesting that the existence of this gene family enables the same function to be expressed under different
transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated
in some hereditary disorders, such as dyskeratosis congenita. Alternative splicing results in multiple transcript
variants. Read-through transcription also exists between this gene and the downstream melanoma antigen family A,
5 (MAGEA5) gene.(provided by RefSeq, Oct 2011)

GeneCards Summary for MAGEA10 Gene: 
MAGEA10 (melanoma antigen family A, 10) is a protein-coding gene. Diseases associated with MAGEA10 include intrahepatic cholangiocarcinoma, and stomach cancer. An important paralog of this gene is MAGEC2.

UniProtKB/Swiss-Prot: MAGAA_HUMAN, P43363
Function: Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor
progression




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.2  NT_167198.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MAGEA10 gene promoter:
         NCX/Ncx   MEF-2A   POU2F1   GATA-6   Nkx6-1   FOXJ2 (long isoform)   POU2F1a   aMEF-2   FOXJ2   En-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMAGEA10 promoter sequence
   Search SABiosciences Chromatin IP Primers for MAGEA10

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAGEA10


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq28   Ensembl cytogenetic band:  Xq28   HGNC cytogenetic band: Xq28

MAGEA10 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MAGEA10 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM151302:  view genomic region     (about GC identifiers)

Start:
151,301,782 bp from pter      End:
151,307,033 bp from pter
Size:
5,252 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MAGAA_HUMAN, P43363 (See protein sequence)
Recommended Name: Melanoma-associated antigen 10  
Size: 369 amino acids; 40780 Da
Subcellular location: Nucleus

Explore the universe of human proteins at neXtProt for MAGEA10: NX_P43363

Explore proteomics data for MAGEA10 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P43363

  • MAGEA10 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MAGEA10 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001011543.2  NP_001238757.1  NP_066386.2  

    ENSEMBL proteins: 
     ENSP00000359347   ENSP00000406161   ENSP00000391977   ENSP00000464160   ENSP00000462833  
     ENSP00000244096  

    Human Recombinant Protein Products for MAGEA10: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for MAGEA10
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for MAGEA10
    GenScript Custom Purified and Recombinant Proteins Services for MAGEA10
    Novus Biologicals MAGEA10 Protein
    Novus Biologicals MAGEA10 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MAGEA10 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    MAGEA10 for ontologies           About GeneDecksing



    MAGEA10 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for MAGEA10
    GenScript Custom Superior Antibodies Services for MAGEA10
    Novus Biologicals MAGEA10 Antibodies
    Search for Antibodies for MAGEA10 at Abcam
    Cloud-Clone Corp. Antibodies for MAGEA10 
    ThermoFisher Antibody for MAGEA10
    LSBio Antibodies in human, mouse, rat for MAGEA10 

    Assay Products for MAGEA10: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for MAGEA10
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for MAGEA10
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for MAGEA10 
    Cloud-Clone Corp. CLIAs for MAGEA10


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR021072 Melanoma_ass_antigen_N
     IPR002190 MAGE

    Graphical View of Domain Structure for InterPro Entry P43363

    ProtoNet protein and cluster: P43363

    1 Blocks protein domain: IPB002190 MAGE protein

    UniProtKB/Swiss-Prot: MAGAA_HUMAN, P43363
    Similarity: Contains 1 MAGE domain


    MAGEA10 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MAGAA_HUMAN, P43363
    Function: Not known, though may play a role in embryonal development and tumor transformation or aspects of tumor
    progression

         Genatlas biochemistry entry for MAGEA10:
    human melanoma antigen,family A,member 10,expressed in placenta,melanoma and testis

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for MAGEA10 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MAGEA10

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MAGEA10 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MAGEA10 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MAGEA10
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate MAGEA10
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for MAGEA10
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MAGEA10

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for MAGEA10
    Sirion Biotech Customized adenovirus for overexpression of MAGEA10

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for MAGEA10 (see all 11)
    OriGene ORF clones in mouse, rat for MAGEA10
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): MAGEA10 (NM_021048)
    Sino Biological Human cDNA Clone for MAGEA10
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MAGEA10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAGEA10
    Sirion Biotech Customized lentivirus for stable overexpression of MAGEA10 
                         Customized lentivirus expression plasmids for stable overexpression of MAGEA10 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for MAGEA10
    Search LifeMap BioReagents cell lines for MAGEA10
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAGEA10


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MAGEA10

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for MAGEA10 (ENSP000002440964) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MAGEA10 (MAGAA)

    Search CenterWatch for drugs/clinical trials and news about MAGEA10 / MAGAA

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MAGEA10 gene (3 alternative transcripts): 
    NM_001011543.2  NM_001251828.1  NM_021048.4  

    Unigene Cluster for MAGEA10:

    Melanoma antigen family A, 10
    Hs.18048  [show with all ESTs]
    Unigene Representative Sequence: NM_001011543
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000370323(uc004ffk.3 uc004ffm.2 uc004ffl.3) ENST00000444834
    ENST00000427322 ENST00000583480 ENST00000579960 ENST00000244096
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MAGEA10
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate MAGEA10
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for MAGEA10
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MAGEA10
    Clone
    Products:
         
    OriGene clones in human, mouse for MAGEA10 (see all 11)
    OriGene ORF clones in mouse, rat for MAGEA10
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): MAGEA10 (NM_021048)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MAGEA10
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAGEA10
    Sirion Biotech Customized lentivirus for stable overexpression of MAGEA10 
                         Customized lentivirus expression plasmids for stable overexpression of MAGEA10 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for MAGEA10
    OriGene qSTAR qPCR primer pairs in human, mouse for MAGEA10
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MAGEA10
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAGEA10
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAGEA10

    Additional mRNA sequence: 

    AK314161.1 AY310324.1 AY522506.1 AY531264.1 BC004105.2 

    7 DOTS entries:

    DT.86849784  DT.91676023  DT.95103326  DT.97836077  DT.100746182  DT.423199  DT.423198 

    24/48 AceView cDNA sequences (see all 48):

    BG477105 BG477980 CR622868 AY531264 CB158974 BE277360 BQ217649 BG477436 
    AI142010 BX335540 BX109673 NM_021048 BE730450 BG478456 BE389926 BX097006 
    BM458898 BU167137 BX335541 BE277068 AI200443 BC004105 BG478664 NM_021049 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for MAGEA10    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3a · 3b ^ 4 ^ 5
    SP1:                                                      
    SP2:                                      -               
    SP3:                                -     -               
    SP4:                                                      


    ECgene alternative splicing isoforms for MAGEA10

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MAGEA10 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATTTTACTCA
    MAGEA10 Expression
    About this image


    See MAGEA10 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MAGEA10

    SOURCE GeneReport for Unigene cluster: Hs.18048

    UniProtKB/Swiss-Prot: MAGAA_HUMAN, P43363
    Tissue specificity: Expressed in many tumors of several types, such as melanoma, head and neck squamous cell
    carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for spermatogonia, spermatocytes
    and placenta

        SABiosciences Custom PCR Arrays for MAGEA10
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for MAGEA10
    OriGene qSTAR qPCR primer pairs in human, mouse for MAGEA10
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MAGEA10
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAGEA10
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAGEA10
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAGEA10

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of human and mouse.

    Orthologs for MAGEA10 gene from 1/4 species (see all 4)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Magea101 , 5 melanoma antigen family A, 101, 5 68.12(n)1
    56.7(a)1
      X (37.23 cM)5
    2368521  NM_001085506.11  NP_001078975.11 
     723818705 


    ENSEMBL Gene Tree for MAGEA10 (if available)
    TreeFam Gene Tree for MAGEA10 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MAGEA10 gene
    MAGEC22  MAGEA9B2  MAGEB52  MAGEB162  MAGEB12  MAGEB42  MAGEC12  MAGED42  
    MAGEA82  MAGED22  MAGEA122  MAGEA92  MAGEB172  MAGEB102  MAGEA62  MAGED12  
    MAGEA22  MAGEA32  MAGEB22  NDN2  MAGEB32  MAGED4B2  MAGEA42  MAGEA12  
    MAGEB182  MAGEA2B2  MAGEB62  MAGEL22  TRO2  MAGEA112  NDNL22  MAGEF12  
    18/35 SIMAP similar genes for MAGEA10 using alignment to 5 protein entries:     MAGAA_HUMAN (see all proteins) (see all similar genes):
    MAGEC4    MAGEC1    MAGEC3    MAGEA9B    MAGEH1    MAGEB16
    MAGEA13P    NDNL2    TRO    MAGEA8    MAGEB1    MAGEB4
    MAGE-B1    MAGEA12    MAGEB18    MAGEB2    MAGEB5    MAGEC2

    MAGEA10 for paralogs           About GeneDecksing


    5 Pseudogenes.org Pseudogenes for MAGEA10
    PGOHUM00000241578 PGOHUM00000241595 PGOHUM00000241689 PGOHUM00000241756 PGOHUM00000242044


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    3 SNPs in MAGEA10 are shown    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0534964
    ----see VAR_0534962 V I mis40--------
    VAR_0245284
    ----see VAR_0245282 R K mis40--------
    rs1830911871,2
    C--140162821(+) TATAAC/TATTTC 3 -- us2k10--------

    HapMap Linkage Disequilibrium report for MAGEA10 (151301782 - 151307033 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 1 variation for MAGEA10:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv520971CNV Gain19592680

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing MAGEA10
    DNA2.0 Custom Variant and Variant Library Synthesis for MAGEA10

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 300343    OMIM disorders: --

    12 diseases for MAGEA10:    About MalaCards
    intrahepatic cholangiocarcinoma    stomach cancer    esophageal adenocarcinoma    dyskeratosis congenita
    melanoma    multiple myeloma    cholangiocarcinoma    myeloma
    esophagitis    squamous cell carcinoma    adenocarcinoma    breast cancer


    MAGEA10 for disorders           About GeneDecksing

    2 Novoseek inferred disease relationships for MAGEA10 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    melanoma 43 3 10446460 (2), 10521804 (1)
    tumors 14.2 2 10446460 (1), 10521804 (1)


    Export disorders for MAGEA10 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MAGEA10 gene, integrated from 9 sources (see all 21):
    (articles sorted by number of sources associating them with MAGEA10)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. MAGE-A10 is a nuclear protein frequently expressed in high percentages of tumor cells in lung, skin and urothelial malignancies. (PubMed id 21710496)1, 2 Schultz-Thater E....Spagnoli G.C. (2011)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. The melanoma antigen gene (MAGE) family is clustered in the chromosomal band Xq28. (PubMed id 8575766)1, 3 Rogner U.C....Poustka A. (1995)
    4. Structure, chromosomal localization, and expression of 12 genes of the MAGE family. (PubMed id 7927540)1, 2 De Plaen E.... Boon T. (1994)
    5. Melanoma-associated antigens in esophageal adenocarcinoma: identification of novel MAGE-A10 splice variants. (PubMed id 15355897)1, 9 Lin J....Beer D.G. (2004)
    6. cDNA and protein characterization of human MAGE-10. (PubMed id 10446460)1, 9 Rimoldi D....Cerottini J.C. (1999)
    7. High expression of MAGE-A10 cancer-testis antigen in t riple-negative breast cancer. (PubMed id 22116775)1 Badovinac Crnjevic T....Nera S. (2012)
    8. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    9. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    10. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4109 HGNC: 6797 AceView: MAGEA10andMAGEA5 Ensembl:ENSG00000124260 euGenes: HUgn4109
    ECgene: MAGEA10 H-InvDB: MAGEA10

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MAGEA10 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for MAGEA10 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MAGEA10 gene:
    Search GeneIP for patents involving MAGEA10

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for MAGEA10  
     OriGene qPCR primer pairs and template standards for MAGEA10   OriGene Protein Over-expression Lysate for MAGEA10  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for MAGEA10  
     OriGene qSTAR qPCR primer pairs in human, mouse for MAGEA10   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for MAGEA10   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for MAGEA10   OriGene Custom Protein Services for MAGEA10  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MAGEA10
     QIAGEN SeqTarget long-range PCR primers for resequencing MAGEA10
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAGEA10
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MAGEA10
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAGEA10
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAGEA10
     GenScript Custom Purified and Recombinant Proteins Services for MAGEA10 GenScript cDNA clones with any tag delivered in your preferred vector for MAGEA10
     GenScript Custom Assay Services for MAGEA10 GenScript Custom Superior Antibodies Services for MAGEA10
     GenScript Custom overexpressing Cell Line Services for MAGEA10 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in MAGEA10 promoter
     Search Chromatin IP Primers for MAGEA10
     RT2 qPCR Primer Assay in human, mouse, rat MAGEA10
     Search GNC Networks for MAGEA10
     SABiosciences Custom PCR Arrays for MAGEA10
     Search Tocris compounds for MAGEA10 (MAGAA)
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     cDNA Clones for MAGEA10
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     MAGEA10 antibodies
     MAGEA10 proteins
     MAGEA10 lysates
     Search for Antibodies for MAGEA10 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for MAGEA10
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for MAGEA10
     Antibodies for MAGEA10
     ELISAs for MAGEA10
     CLIAs for MAGEA10
     Search LifeMap BioReagents cell lines for MAGEA10
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAGEA10
     Browse SwitchGear 3'UTR luciferase reporter plasmids for MAGEA10
     SwitchGear Promoter luciferase reporter plasmids for MAGEA10
     ThermoFisher Antibody for MAGEA10
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAGEA10
     inGenious Targeting Laboratory - Custom generated mouse model solutions for MAGEA10
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MAGEA10
    Customized:
     lentivirus for stable overexpression of MAGEA10
     lentivirus expression plasmids for stable overexpression of MAGEA10
     adenovirus for overexpression of MAGEA10
     LSBio Antibodies in human, mouse, rat for MAGEA10
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      MAGEA10 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 106 solr: 1.4