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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MAGEA1 Gene

protein-coding   GIFtS: 65
GCID: GC0XM152481

Melanoma Antigen Family A, 1 (Directs Expression Of Antigen...


(Previous symbol: MAGE1)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Melanoma Antigen Family A, 1 (Directs Expression Of Antigen MZ2-E)1 2     Cancer/Testis Antigen 1.12 3
MAGE11 2 3 5     CT1.12 3
Melanoma Antigen Family A 11 2     MAGE-1 Antigen2 3
Melanoma Antigen MAGE-11 2     Cancer/Testis Antigen Family 11
Melanoma-Associated Antigen 11 2     Member 11
Melanoma-Associated Antigen MZ2-E1 2     Cancer/Testis Antigen Family 1, Member 12
Antigen MZ2-E2 3     MAGE1A3

External Ids:    HGNC: 67961   Entrez Gene: 41002   Ensembl: ENSG000001986817   OMIM: 3000165   UniProtKB: P433553   

Export aliases for MAGEA1 gene to outside databases

Previous GC identifers: GC0XM146635 GC0XM148952 GC0XM150043 GC0XM150912 GC0XM151965 GC0XM152134 GC0XM141141


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MAGEA1 Gene:
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence
identity to each other. The promoters and first exons of the MAGEA genes show considerable variability,
suggesting that the existence of this gene family enables the same function to be expressed under different
transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated
in some hereditary disorders, such as dyskeratosis congenita. (provided by RefSeq, Jul 2008)

GeneCards Summary for MAGEA1 Gene: 
MAGEA1 (melanoma antigen family A, 1 (directs expression of antigen MZ2-E)) is a protein-coding gene. Diseases associated with MAGEA1 include biphasic synovial sarcoma, and ocular melanoma, and among its related super-pathways are Notch signaling pathway. GO annotations related to this gene include protein binding and histone deacetylase binding. An important paralog of this gene is MAGEC2.

UniProtKB/Swiss-Prot: MAGA1_HUMAN, P43355
Function: May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone
deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal
development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by
autologous cytolytic T-lymphocytes

Gene Wiki entry for MAGEA1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.2  NT_167198.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MAGEA1 gene promoter:
         Pbx1a   NF-YA   NF-YC   Olf-1   CBF-C   NF-YB   CP1C   CP1A   MRF-2   NF-Y   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMAGEA1 promoter sequence
   Search SABiosciences Chromatin IP Primers for MAGEA1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAGEA1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq28   Ensembl cytogenetic band:  Xq28   HGNC cytogenetic band: Xq28

MAGEA1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MAGEA1 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM152481:  view genomic region     (about GC identifiers)

Start:
152,481,522 bp from pter      End:
152,486,116 bp from pter
Size:
4,595 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MAGA1_HUMAN, P43355 (See protein sequence)
Recommended Name: Melanoma-associated antigen 1  
Size: 309 amino acids; 34342 Da
Subunit: Interacts with SNW1 and HDCA1
Subcellular location: Cytoplasm. Nucleus
2 PDB 3D structures from and Proteopedia for MAGEA1:
1W72 (3D)        3BO8 (3D)    
Secondary accessions: B2RC81 O00346

Explore the universe of human proteins at neXtProt for MAGEA1: NX_P43355

Explore proteomics data for MAGEA1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P43355

  • MAGEA1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MAGEA1 Protein Expression
    REFSEQ proteins: NP_004979.3  
    ENSEMBL proteins: 
     ENSP00000349085  

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    Cloud-Clone Corp. Proteins for MAGEA1 

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA15316101
    GO:0005737cytoplasm IDA15316101
    GO:0005886plasma membrane TAS1840703

    MAGEA1 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR021072 Melanoma_ass_antigen_N
     IPR002190 MAGE

    Graphical View of Domain Structure for InterPro Entry P43355

    ProtoNet protein and cluster: P43355

    1 Blocks protein domain: IPB002190 MAGE protein

    UniProtKB/Swiss-Prot: MAGA1_HUMAN, P43355
    Similarity: Contains 1 MAGE domain


    MAGEA1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MAGA1_HUMAN, P43355
    Function: May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone
    deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal
    development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by
    autologous cytolytic T-lymphocytes

         Genatlas biochemistry entry for MAGEA1:
    melanoma antigen,family A,member 1,directing expression of antigen MZ2-E,expressed in melanoma,testis,advanced
    gastric carcinomas and hepatocellular carcinomas

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI15316101
    GO:0042826histone deacetylase binding IDA15316101
         
    MAGEA1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for MAGEA1:
     Cells with protrusions 

    Animal Models:
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for MAGEA1 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Notch signaling pathway
    Delta-Notch Signaling Pathway0.33


    1 BioSystems Pathway for MAGEA1
        Delta-Notch Signaling Pathway



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MAGEA1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

    5/26 Interacting proteins for MAGEA1 (P433551, 2, 3 ENSP000003490854) via UniProtKB, MINT, STRING, and/or I2D (see all 26)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UQCRBP149272, 3, ENSP000002870224MINT-67618 I2D: score=5 STRING: ENSP00000287022
    SNW1Q135731, 3, ENSP000002615314EBI-740978,EBI-632715 I2D: score=1 STRING: ENSP00000261531
    ENSG00000223531Q9BZY93, ENSP000003986774I2D: score=4 STRING: ENSP00000398677
    ENSG00000225130Q9BZY93, ENSP000003916854I2D: score=4 STRING: ENSP00000391685
    TRIM31Q9BZY93, ENSP000003659244I2D: score=4 STRING: ENSP00000365924
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IDA15316101
    GO:0006351transcription, DNA-dependent IEA--
    GO:0045746negative regulation of Notch signaling pathway IDA15316101

    MAGEA1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    MAGEA1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MAGEA1 (MAGA1)

    4 Novoseek inferred chemical compound relationships for MAGEA1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    5-aza-2'deoxycytidine 73.6 16 16140943 (2), 10523621 (2), 7511051 (1), 16687489 (1) (see all 11)
    sodium bisulfite 54.2 3 17007017 (2), 12443884 (1)
    paraffin 12.4 2 10945497 (1), 8917707 (1)
    ethidium bromide 8.08 1 8647642 (1)

    Search CenterWatch for drugs/clinical trials and news about MAGEA1 / MAGA1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MAGEA1 gene: 
    NM_004988.4  

    Unigene Cluster for MAGEA1:

    Melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
    Hs.72879  [show with all ESTs]
    Unigene Representative Sequence: NM_004988
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000356661(uc004fhf.2)
    miRNA
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAGEA1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAGEA1

    Additional mRNA sequence: 

    AF463515.1 AK314979.1 AY148486.1 BC017555.1 BT009789.1 EU161102.1 

    1 DOTS entry:

    DT.303176 

    19 AceView cDNA sequences:

    CA428506 AW103876 CA423766 BM989182 BX282460 BU153093 AF463515 BM459064 
    BQ224380 BC017555 BT009789 BU175213 NM_004988 AY148486 BU157186 BV196058 
    BV196059 BG030623 BU564836 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MAGEA1 expression in normal human tissues (normalized intensities)      MAGEA1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AGGCCCATTC
    MAGEA1 Expression
    About this image


    MAGEA1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Gonad
             Oogonia Ovigerous Cord
     
     Testis (Reproductive System)
             Spermatogonium Type B Seminiferous Tubules
     
     Ovary (Reproductive System)
             Oogonia Ovigerous Cord

    See MAGEA1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MAGEA1

    SOURCE GeneReport for Unigene cluster: Hs.72879

    UniProtKB/Swiss-Prot: MAGA1_HUMAN, P43355
    Tissue specificity: Expressed in many tumors of several types, such as melanoma, head and neck squamous cell
    carcinoma, lung carcinoma and breast carcinoma, but not in normal tissues except for testes. Never expressed in
    kidney tumors, leukemias and lymphomas

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAGEA1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
      --

    ENSEMBL Gene Tree for MAGEA1 (if available)
    TreeFam Gene Tree for MAGEA1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MAGEA1 gene
    MAGEC22  MAGEA9B2  MAGEB52  MAGEB162  MAGEB12  MAGEB42  MAGEC12  MAGED42  
    MAGEA82  MAGED22  MAGEA122  MAGEA92  MAGEB172  MAGEB102  MAGEA62  MAGED12  
    MAGEA22  MAGEA32  MAGEB22  NDN2  MAGEB32  MAGED4B2  MAGEA42  MAGEA102  
    MAGEB182  MAGEA2B2  MAGEB62  MAGEL22  TRO2  MAGEA112  NDNL22  MAGEF12  
    18/37 SIMAP similar genes for MAGEA1 using alignment to 3 protein entries:     MAGA1_HUMAN (see all proteins) (see all similar genes):
    MAGEA4    MAGEA12    MAGEA8    MAGEA5    MAGEA2    MAGEA2B
    MAGEA9B    MAGEA3    MAGEA6    MAGEH1    MAGEA11    TRO
    MAGEB4    MAGEB17    MAGEB18    MAGEB5    MAGEA9    MAGE-B1

    MAGEA1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/129 SNPs in MAGEA1 are shown (see all 129)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0365814
    A breast cancer sample4--see VAR_0365812 K T mis40--------
    rs1855605201,2
    --152348319(+) TCTTGC/TGCTGT 1 -- ds50010--------
    rs726164251,2
    --152348322(+) TGCGCC/TGTGTT 1 -- ds50010--------
    rs1914380391,2
    --152348350(+) AAGCAA/TAGGAC 1 -- ds50010--------
    rs790774071,2
    C--152348502(+) CTCCCC/TCAGAA 1 -- ds50010--------
    rs1839029181,2
    --152348574(+) TCACCC/TGGAGC 1 -- ds50010--------
    rs1887309361,2
    --152348667(+) GACTCC/TACGAC 1 -- ds50010--------
    rs19852181,2
    C,F--152348712(+) ATCTCC/TACTAC 1 -- ds50011Minor allele frequency- T:0.00NA 80
    rs1815136541,2
    --152348746(+) AGATGC/TTCAGT 1 -- ds50010--------
    rs581080541,2
    C,F--152348771(+) AGAGCG/CAGTGA 1 -- ds50011Minor allele frequency- C:0.00CSA 1

    HapMap Linkage Disequilibrium report for MAGEA1 (152481522 - 152486116 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for MAGEA1:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv270e55CNV Gain17911159
    dgv2n30CNV Gain18288195
    nsv9998CNV Gain18304495
    esv33199CNV Gain+Loss17666407
    dgv2494e1CNV Complex17122850
    nsv218OTHER Inversion15895083
    nsv7467OTHER Inversion18451855


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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 300016    OMIM disorders: --

    20/45 diseases for MAGEA1 (see all 45):    About MalaCards
    biphasic synovial sarcoma    ocular melanoma    juvenile rheumatoid arthritis    oral squamous cell carcinoma
    seminoma    benign tumors    dyskeratosis congenita    testicular cancer
    synovial sarcoma    intrahepatic cholangiocarcinoma    non-small cell lung carcinoma    gout
    liver cirrhosis    melanoma    germ cell tumors    vitiligo
    hemangioma    hepatocellular carcinoma    esophagitis    gastric cancer

    1 disease from the University of Copenhagen DISEASES database for MAGEA1:
    Melanoma

    MAGEA1 for disorders           About GeneDecksing

    10/50 Novoseek inferred disease relationships for MAGEA1 gene (see all 50)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    melanoma 80.3 108 7511051 (5), 7814879 (4), 8707418 (3), 17957795 (3) (see all 61)
    testicular cancer 77.2 6 11668506 (1), 11953832 (1), 16467087 (1), 17208940 (1) (see all 6)
    tumors 63.9 211 8900375 (5), 18820946 (5), 18505125 (4), 15143172 (4) (see all 96)
    hepatocellular carcinoma 59.8 43 19260505 (4), 10961717 (3), 16082588 (2), 10592101 (2) (see all 24)
    cancer 53.1 36 17007017 (3), 9131385 (2), 15703841 (2), 12877803 (2) (see all 25)
    hepatic hemangioma 49.9 1 15498320 (1)
    pediatric solid tumor 46.7 1 8900370 (1)
    gastric carcinoma 44.4 11 11289403 (3), 9121149 (3), 9854470 (3), 7557134 (2)
    ocular melanoma 40.3 2 9220316 (2)
    leukemia b-cell 38.4 1 7656275 (1)

    Genetic Association Database (GAD): MAGEA1
    Human Genome Epidemiology (HuGE) Navigator: MAGEA1 (1 document)

    Export disorders for MAGEA1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MAGEA1 gene, integrated from 9 sources (see all 251):
    (articles sorted by number of sources associating them with MAGEA1)
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    1. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. (PubMed id 1840703)1, 2, 3, 9 van der Bruggen P.... Boon T. (1991)
    2. [The genetic polymorphism of melanoma-associated antigen 1 in Chinese normal donors and hepatoma patients] (PubMed id 15059299)1, 2, 9 Wang L.P....Wei L. (2004)
    3. MAGE-1 gene product is a cytoplasmic protein. (PubMed id 7927954)1, 2, 9 Schultz-Thater E.... Spagnoli G.C. (1994)
    4. Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes. (PubMed id 8113684)1, 2, 9 Gaugler B.... Boon T. (1994)
    5. Frequent MAGE mutations in human melanoma. (PubMed id 20862285)1, 4 Caballero O.L....Simpson A.J. (2010)
    6. MAGE-A1 interacts with adaptor SKIP and the deacetylase HDAC1 to repress transcription. (PubMed id 15316101)1, 2 Laduron S....De Plaen E. (2004)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    8. Comparative genome sequence analysis of the Bpa/Str region in mouse and man. (PubMed id 10854409)1, 2 Mallon A.-M....Brown S.D.M. (2000)
    9. Cloning and analysis of MAGE-1-related genes. (PubMed id 8037761)1, 2 Ding M.... Fenton R.G. (1994)
    10. MAGE-A1 expression is associated with good prognosis in neuroblastoma tumors. (PubMed id 18820946)1, 9 Grau E....Castel V. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4100 HGNC: 6796 AceView: MAGEA1 Ensembl:ENSG00000198681 euGenes: HUgn4100
    ECgene: MAGEA1 H-InvDB: MAGEA1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MAGEA1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for MAGEA1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MAGEA1 gene:
    Search GeneIP for patents involving MAGEA1

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