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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MAGEA1 Gene

protein-coding   GIFtS: 62
GCID: GC0XM152481

melanoma antigen family A, 1 (directs expression of antigen...


(Previous symbol: MAGE1)
 Explore 57 diseases affiliated with
MAGEA1 via our new
 Human Malady Compendium 
Biological research products
for MAGEA1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Melanoma Antigen Family A, 1 (Directs Expression Of Antigen MZ2-E)1 2     Cancer/Testis Antigen Family 1, Member 12
MAGE11 2 3 5     Melanoma Antigen Family A 12
CT1.11 2 3     Melanoma Antigen MAGE-12
Antigen MZ2-E2 3     Melanoma-Associated Antigen 12
Cancer/Testis Antigen 1.12 3     Melanoma-Associated Antigen MZ2-E2
MAGE-1 Antigen2 3     MAGE1A3
MGC93261     

External Ids:    HGNC: 67961   Entrez Gene: 41002   Ensembl: ENSG000001986817   OMIM: 3000165   UniProtKB: P433553   

Export aliases for MAGEA1 gene to outside databases

Previous GC identifers: GC0XM146635 GC0XM148952 GC0XM150043 GC0XM150912 GC0XM151965 GC0XM152134 GC0XM141141


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MAGEA1:
This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence
identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting
that the existence of this gene family enables the same function to be expressed under different transcriptional
controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary
disorders, such as dyskeratosis congenita. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: MAGA1_HUMAN, P43355
Function: May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone
deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal
development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous
cytolytic T-lymphocytes

Gene Wiki entry for MAGEA1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.1  NT_167198.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MAGEA1 gene promoter:
         Pbx1a   NF-YA   NF-YC   Olf-1   CBF-C   NF-YB   CP1C   CP1A   MRF-2   NF-Y   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidMAGEA1 promoter sequence
   Search SABiosciences Chromatin IP Primers for MAGEA1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAGEA1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xq28   Ensembl cytogenetic band:  Xq28   HGNC cytogenetic band: Xq28

MAGEA1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MAGEA1 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM152481:  view genomic region     (about GC identifiers)

Start:
152,481,522 bp from pter      End:
152,486,116 bp from pter
Size:
4,595 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MAGA1_HUMAN, P43355 (See protein sequence)
Recommended Name: Melanoma-associated antigen 1  
Size: 309 amino acids; 34342 Da
Subunit: Interacts with SNW1 and HDCA1
Subcellular location: Cytoplasm. Nucleus
2 PDB 3D structures from and Proteopedia for MAGEA1:
1W72 (3D)        3BO8 (3D)    
Secondary accessions: B2RC81 O00346

Explore the universe of human proteins at neXtProt for MAGEA1: NX_P43355

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P43355

  • MAGEA1 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_004979.3  
    ENSEMBL proteins: 
     ENSP00000349085  

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    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA15316101
    GO:0005737cytoplasm IDA15316101
    GO:0005886plasma membrane TAS1840703


    MAGEA1 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    MAGEA1 for domains           About GeneDecksing

    2 InterPro domains/families:
     IPR021072 Melanoma_ass_antigen_N
     IPR002190 MAGE

    Graphical View of Domain Structure for InterPro Entry P43355

    ProtoNet protein and cluster: P43355

    1 Blocks protein family: IPB002190 MAGE protein

    UniProtKB/Swiss-Prot: MAGA1_HUMAN, P43355
    Similarity: Contains 1 MAGE domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: MAGA1_HUMAN, P43355
    Function: May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone
    deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal
    development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous
    cytolytic T-lymphocytes

         Genatlas biochemistry entry for MAGEA1:
    melanoma antigen,family A,member 1,directing expression of antigen MZ2-E,expressed in melanoma,testis,advanced gastric
    carcinomas and hepatocellular carcinomas

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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0042826histone deacetylase binding IDA15316101


    MAGEA1 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for MAGEA1:
     Cells with protrusions 


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Notch Signaling Pathway
    Delta-Notch Signaling Pathway0.27


    1 BioSystems Pathway for MAGEA1 
        Delta-Notch Signaling Pathway


    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MAGEA1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

    5/21 Interacting proteins for MAGEA1 (P433551, 2, 3 ENSP000003490854) via UniProtKB, MINT, STRING, and/or I2D (see all 21)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UQCRBP149272, 3, ENSP000002870224MINT-67618 I2D: score=5 STRING: ENSP00000287022
    SNW1Q135731, 3, ENSP000002615314EBI-740978,EBI-632715 I2D: score=1 STRING: ENSP00000261531
    HLA-AP304433, ENSP000003660054I2D: score=2 I2D: score=1 STRING: ENSP00000366005
    HDAC1Q135471, 3, ENSP000003626494EBI-740978,EBI-301834 I2D: score=2 STRING: ENSP00000362649
    SH3GLB2Q9NR462, 3, ENSP000003616404MINT-67557 I2D: score=5 STRING: ENSP00000361640
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000122negative regulation of transcription from RNA polymerase II promoter IDA15316101
    GO:0006351transcription, DNA-dependent IEA--
    GO:0045746negative regulation of Notch signaling pathway IDA15316101


    MAGEA1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    MAGEA1 for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MAGEA1
    4 Novoseek chemical compound relationships for MAGEA1 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    5-aza-2'deoxycytidine 73.6 16 16140943 (2), 10523621 (2), 7511051 (1), 16687489 (1) (see all 11)
    sodium bisulfite 54.2 3 17007017 (2), 12443884 (1)
    paraffin 12.4 2 10945497 (1), 8917707 (1)
    ethidium bromide 8.08 1 8647642 (1)

    Search CenterWatch for drugs/clinical trials and news about MAGEA1 / MAGA1 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MAGEA1 gene: 
    NM_004988.4  

    Unigene Cluster for MAGEA1:

    Melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
    Hs.72879  [show with all ESTs]
    Unigene Representative Sequence: NM_004988
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000356661(uc004fhf.2)

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    Additional cDNA sequence: 

    AF463515.1 AK314979.1 AY148486.1 BC017555.1 BT009789.1 EU161102.1 

    1 DOTS entry:

    DT.303176 

    19 AceView cDNA sequences:

    BM989182 CA428506 AW103876 CA423766 BC017555 AY148486 NM_004988 BU157186 
    AF463515 BT009789 BM459064 BV196058 BQ224380 BU175213 BV196059 BX282460 
    BU153093 BG030623 BU564836 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MAGEA1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AGGCCCATTC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image

    MAGEA1 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    OvaryOvigerous CordOogoniaFemale Gametocytes, Germ Cells
    TestisSeminiferous TubulesSpermatogonium Type BGerm Cells, Male Gametocytes
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See MAGEA1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MAGEA1

    SOURCE GeneReport for Unigene cluster: Hs.72879

    UniProtKB/Swiss-Prot: MAGA1_HUMAN, P43355
    Tissue specificity: Expressed in many tumors of several types, such as melanoma, head and neck squamous cell carcinoma,
    lung carcinoma and breast carcinoma, but not in normal tissues except for testes. Never expressed in kidney tumors,
    leukemias and lymphomas

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    In Situ
    Assay Products:
     

     
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for MAGEA1 gene from 3/15 species (see all 15)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    36(a)
    1 → many
    1(205669616-205678308)
    zebrafish
    (Danio rerio)
    Actinopterygii ndnl26
    necdin-like 2
    27(a)
    1 → many
    23(13012414-13025121)
    fruit fly
    (Drosophila melanogaster)
    Insecta MAGE6
    MAGE
    20(a)
    1 → many
    3R(2979960-2980898)


    ENSEMBL Gene Tree for MAGEA1 (if available)
    TreeFam Gene Tree for MAGEA1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MAGEA1 gene
    MAGEC22  MAGEA9B2  MAGEB52  MAGEB162  MAGEB42  MAGEB12  MAGEC12  MAGED42  
    MAGEA82  MAGED22  MAGEA122  MAGEA92  MAGEB172  MAGEB102  MAGEA62  MAGEE12  
    MAGED12  MAGEA22  MAGEC32  MAGEA32  NDN2  MAGEB22  MAGEB32  MAGED4B2  
    MAGEE22  MAGEA42  MAGEA102  MAGEB182  MAGEA2B2  MAGEB62  MAGEL22  TRO2  
    MAGEA112  NDNL22  MAGEF12  
    18/37 SIMAP similar genes for MAGEA1 using alignment to 3 protein entries:     MAGA1_HUMAN (see all proteins) (see all similar genes):
    MAGEA4    MAGEA12    MAGEA8    MAGEA5    MAGEA2    MAGEA2B
    MAGEA9B    MAGEA3    MAGEA6    MAGEH1    MAGEA11    TRO
    MAGEB4    MAGEB17    MAGEB18    MAGEB5    MAGEA9    MAGE-B1

    MAGEA1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/104 NCBI SNPs in MAGEA1 are shown (see all 104    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr X posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1855605201,2
    --152481065(+) TCTTGC/TGCTGT 1 -- ds50010--------
    rs726164251,2
    --152481068(+) TGCGCC/TGTGTT 1 -- ds50010--------
    rs1914380391,2
    --152481096(+) AAGCAA/TAGGAC 1 -- ds50010--------
    rs790774071,2
    C,--152481248(+) CTCCCC/TCAGAA 1 -- ds50010--------
    rs1839029181,2
    --152481320(+) TCACCC/TGGAGC 1 -- ds50010--------
    rs1887309361,2
    --152481413(+) GACTCC/TACGAC 1 -- ds50010--------
    rs19852181,2
    C,--152481458(+) ATCTCC/TACTAC 1 -- ds50011Minor allele frequency- T:0.00NA 80
    rs1815136541,2
    --152481492(+) AGATGC/TTCAGT 1 -- ds50010--------
    rs581080541,2
    C,--152481517(+) AGAGCG/CAGTGA 1 -- ds50011Minor allele frequency- C:0.00CSA 1
    rs455583441,2
    C,--152481634(+) TATAAA/GGCAAG 1 -- ut311Minor allele frequency- G:0.00CSA 1

    HapMap Linkage Disequilibrium report for MAGEA1 (152481522 - 152486116 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 19 variations for MAGEA1
         3 CNVs: 31574 8314 3259
         13 Indels: 83857 83858 83860 97101 83861 83859 97099 97096 83862 97098 97097 97095 97100
         3 Inversions: 0672 37361 37362
    Locus Specific Mutation Databases (LSDB): MAGEA1

    SABiosciences Cancer Mutation PCR Assays
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    DNA2.0 Custom Variant and Variant Library Synthesis for MAGEA1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    MAGEA1 for disorders           About GeneDecksing

    OMIM gene information: 300016    OMIM disorders: --

    20/57 diseases for MAGEA1 (see all 57):    About MalaCards
    dyskeratosis congenita    dyskeratosis    melanoma    biphasic synovial sarcoma
    non-small cell lung carcinoma    testicular germ cell tumor    germ cell tumor    synovial sarcoma
    squamous cell carcinoma    ocular melanoma    juvenile rheumatoid arthritis    liver cirrhosis
    oral squamous cell carcinoma    esophageal squamous cell carcinoma    benign tumors    transitional cell carcinoma
    testicular cancer    rheumatoid arthritis    acute myeloid leukemia    vulvar cancer

    1 disease from the University of Copenhagen DISEASES database for MAGEA1:
    Melanoma

    10/50 Novoseek disease relationships for MAGEA1 gene (see all 50)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    melanoma 80.3 108 7511051 (5), 7814879 (4), 8707418 (3), 17957795 (3) (see all 61)
    testicular cancer 77.2 6 11668506 (1), 11953832 (1), 16467087 (1), 17208940 (1) (see all 6)
    tumors 63.9 211 8900375 (5), 18820946 (5), 18505125 (4), 15143172 (4) (see all 96)
    hepatocellular carcinoma 59.8 43 19260505 (4), 10961717 (3), 16082588 (2), 10592101 (2) (see all 24)
    cancer 53.1 36 17007017 (3), 9131385 (2), 15703841 (2), 12877803 (2) (see all 25)
    hepatic hemangioma 49.9 1 15498320 (1)
    pediatric solid tumor 46.7 1 8900370 (1)
    gastric carcinoma 44.4 11 11289403 (3), 9121149 (3), 9854470 (3), 7557134 (2)
    ocular melanoma 40.3 2 9220316 (2)
    leukemia b-cell 38.4 1 7656275 (1)

    Human Genome Epidemiology (HuGE) Navigator: MAGEA1 (1 document)

    Export disorders for MAGEA1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MAGEA1 gene, integrated from 9 sources (see all 248):
    (articles sorted by number of sources associating them with MAGEA1)
        Utopia: connect your pdf to the dynamic
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    1. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. (PubMed id 1840703)1, 2, 3, 9 van der Bruggen P.... Boon T. (1991)
    2. [The genetic polymorphism of melanoma-associated antigen 1 in Chinese normal donors and hepatoma patients] (PubMed id 15059299)1, 2, 9 Wang L.P....Wei L. (2004)
    3. MAGE-1 gene product is a cytoplasmic protein. (PubMed id 7927954)1, 2, 9 Schultz-Thater E.... Spagnoli G.C. (1994)
    4. Human gene MAGE-3 codes for an antigen recognized on a melanoma by autologous cytolytic T lymphocytes. (PubMed id 8113684)1, 2, 9 Gaugler B.... Boon T. (1994)
    5. MAGE-A1 interacts with adaptor SKIP and the deacetylase HDAC1 to repress transcription. (PubMed id 15316101)1, 2 Laduron S....De Plaen E. (2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Comparative genome sequence analysis of the Bpa/Str region in mouse and man. (PubMed id 10854409)1, 2 Mallon A.-M....Brown S.D.M. (2000)
    8. Cloning and analysis of MAGE-1-related genes. (PubMed id 8037761)1, 2 Ding M.... Fenton R.G. (1994)
    9. MAGE-A1 expression is associated with good prognosis in neuroblastoma tumors. (PubMed id 18820946)1, 9 Grau E....Castel V. (2009)
    10. Transient down-regulation of DNMT1 methyltransferase leads to activation and stable hypomethylation of MAGE-A1 in melanoma cells. (PubMed id 16497664)1, 9 Loriot A....De Smet C. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 4100 HGNC: 6796 AceView: MAGEA1 Ensembl:ENSG00000198681 euGenes: HUgn4100
    ECgene: MAGEA1 H-InvDB: MAGEA1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MAGEA1 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for MAGEA1 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for MAGEA1 gene:
    Search GeneIP for patents involving MAGEA1

    GeneCards and IP:
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