Aliases for MAG Gene
External Ids for MAG Gene
Previous HGNC Symbols for MAG Gene
Previous GeneCards Identifiers for MAG Gene
The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2010]
GeneCards Summary for MAG Gene
MAG (Myelin Associated Glycoprotein) is a Protein Coding gene. Diseases associated with MAG include Spastic Paraplegia 75 and Demyelinating Polyneuropathy. Among its related pathways are Platelet activation, signaling and aggregation and p75 NTR receptor-mediated signalling. GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is SIGLEC10.
UniProtKB/Swiss-Prot for MAG Gene
Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity).