Aliases for MAG Gene
External Ids for MAG Gene
Previous HGNC Symbols for MAG Gene
Previous GeneCards Identifiers for MAG Gene
The protein encoded by this gene is a type I membrane protein and member of the immunoglobulin superfamily. It is thought to be involved in the process of myelination. It is a lectin that binds to sialylated glycoconjugates and mediates certain myelin-neuron cell-cell interactions. Three alternatively spliced transcripts encoding different isoforms have been described for this gene. [provided by RefSeq, Nov 2010]
GeneCards Summary for MAG Gene
MAG (Myelin Associated Glycoprotein) is a Protein Coding gene. Diseases associated with MAG include spastic paraplegia 75 and chronic polyneuropathy. Among its related pathways are Platelet activation, signaling and aggregation and Signaling by GPCR. GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is SIGLEC10.
UniProtKB/Swiss-Prot for MAG Gene
Adhesion molecule in postnatal neural development that mediates sialic-acid dependent cell-cell interactions between neuronal and myelinating cells. Preferentially binds to alpha-2,3-linked sialic acid (By similarity).