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MAFK Gene

protein-coding GIFtS: 57

GC07P001536

v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)
(Previous names: v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein K )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
FLJ32205 ^²
MGC71717 ^²
NFE2U ^¹, ², ⁵
P18 ^¹, ²

Descriptions
Erythroid transcription factor NF-E2 p18 subunit ^², ³
basic-leucine zipper transcription factor MafK ^²
nuclear factor erythroid-2, ubiquitous (p18) ^²
v-maf avian musculoaponeurotic fibrosarcoma oncogene family, protein K ^²
v-maf musculoaponeurotic fibrosarcoma (avian) oncogene family, protein K ^¹
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K ^²
v-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian) ^²

External Ids
HGNC: 6782¹
Entrez Gene: 7975²
UniProtKB: O60675³
Ensembl: ENSG00000198517⁷

Search outside databases for aliases for MAFK gene

Previous GC identifers: GC07P001214 GC07P001314 GC07P001343

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for MAFK:

The developmentally regulated expression of the globin genes depends on upstream regulatory

elements termed locus control regions (LCRs). LCRs are associated with powerful enhancer activity

that is mediated by the transcription factor NFE2 (nuclear factor erythroid-2). NFE2 recognition

sites are also present in the gene promoters of 2 heme biosynthetic enzymes, porphobilinogen

deaminase (PBGD; MIM 609806) and ferrochelatase (FECH; MIM 612386). NFE2 DNA-binding activity

consists of a heterodimer containing an 18-kD Maf protein (MafF, MafG (MIM 602020), or MafK) and

p45 (MIM 601490). Both subunits are members of the activator protein-1 superfamily of basic

leucine zipper (bZIP) proteins (see MIM 165160). Maf homodimers suppress transcription at NFE2

sites.[supplied by OMIM]

UniProtKB/Swiss-Prot: MAFK_HUMAN, O60675

Function: Since they lack a putative transactivation domain, the small Mafs behave as

transcriptional repressors when they dimerize among themselves. However, they seem to serve as

transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and

recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may

act as competitive repressors of the NF-E2 transcription factor

Gene Wiki entry for MAFK

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the MAFK gene

Entrez Gene cytogenetic band: 7p22.3 Ensembl cytogenetic band: 7p22.3 HGNC cytogenetic band: 7p22

MAFK Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07P001536: (about GC identifiers)

Start:	1,536,894 bp from pter
End:	1,549,205 bp from pter
Size:	12,312 bases
Orientation:	plus strand

1 alternative location:

Chr7+,CRA_TCAG 1,622,776-1,635,087

RefSeq DNA sequence:

NC_000007.12 NT_007819.16 NT_079592.2

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: MAFK_HUMAN, O60675 (See protein sequence)

Recommended Name: Transcription factor MafK

Size: 156 amino acids; 17523 Da

Subunit: Homodimer or heterodimer. It can form high affinity heterodimers with members of the

CNC-bZIP family such as NFE2, NFE2L1/NRF1, NFE2L2/NRF2 and NFE2L3/NRF3

Subcellular location: Nucleus

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_002351.1

ENSEMBL proteins:

ENSP00000386009 ENSP00000344903

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (MAFK)
	Human Recombinant Proteins from Abnova (MAFK)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

About this table

Antibodies for MAFK:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibody Arrays and Antibodies for MAFK
	R&D Systems Antibodies for MAFK
	Antibodies from Abcam (MAFK), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for MAFK

Assays for MAFK:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry O60675

ProtoNet protein and cluster: O60675

1 Blocks protein family: IPB004826 Maf transcription factor

UniProtKB/Swiss-Prot: MAFK_HUMAN, O60675

Similarity: Belongs to the bZIP family. Maf subfamily

Similarity: Contains 1 bZIP domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MAFK)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (MAFK)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002360

Applied Biosystems Silencer® siRNAs for MAFK

Sigma-Aldrich siRNA for MAFK

Sigma-Aldrich shRNA for MAFK

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_002360
Myc/DDK tagged cDNA clone in CMV expression vector: NM_002360
untagged cDNA clone in CMV expression vector: NM_002360

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_002360

UniProtKB/Swiss-Prot: MAFK_HUMAN, O60675

Function: Since they lack a putative transactivation domain, the small Mafs behave as

transcriptional repressors when they dimerize among themselves. However, they seem to serve as

transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and

recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may

act as competitive repressors of the NF-E2 transcription factor

Genatlas biochemistry entry for MAFK:

small MAF protein K,interacting with BACH1,heterodimerizing with NFE2 to form an erythroid and

megakaryocytic cell specific transcription factor,also expressed in neurones from an alternative

promoter at least in mouse,homolog to v-maf fibrosarcoma (avian) oncogene

9 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Mafk):

behavior/neurological	growth/size	hematopoietic system	immune system	lethality-postnatal
lethality-prenatal/perinatal	muscle	nervous system	reproductive system

3 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	transcription factor activity	NAS	9150357
GO:0005515	protein binding	IEA	--
GO:0043565	sequence-specific DNA binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Sigma-Aldrich "Your Favorite Gene" Pathway for MAFK (Your Favorite Gene powered by Ingenuity)

NRF2-mediated Oxidative Stress Response

GeneDecks MAFK for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for MAFK

5/9 Interacting proteins for MAFK (ENSP00000344903³) via UniProtKB, MINT, and/or STRING (see all 9 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
NFE2	ENSP00000312436³	STRING (score=.95)
BACH2	ENSP00000345642³	STRING (score=.872)
C16orf35	ENSP00000262313³	STRING (score=.802)
NFE2L3	ENSP00000056233³	STRING (score=.77)
BACH1	ENSP00000286800³	STRING (score=.755)

About this table

2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006355	regulation of transcription, DNA-dependent	IEA	--
GO:0007399	nervous system development	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for MAFK
1 Novoseek chemical compound relationship for MAFK gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
leucine	48.93	3	9224592 (1), 12388604 (1), 18201722 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MAFK)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (MAFK)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002360

Sigma-Aldrich siRNA for MAFK

Sigma-Aldrich shRNA for MAFK

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_002360

REFSEQ mRNAs for MAFK gene:

NM_002360.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_002360

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_002360
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_002360
                                 untagged cDNA clone in CMV expression vector: NM_002360

Additional cDNA sequence:

AF059194.1 AK056767.1 AK092414.1 AL831913.1 BC012777.2 BC094871.1 BC143040.1 BC143041.1

BC148194.1 BC148265.1 BC152387.1

7 DOTS entries:

DT.95111972 DT.95155752 DT.121047953 DT.121047905 DT.121047936 DT.91870884 DT.121047911

24/185 AceView cDNA sequences (see all 185 ):

BM771206 BC012777 AI573098 BM770991 BM771854 CB109583 BM666495 BM794763

BM770981 AI523804 BM770741 BM771441 BM771231 BU622582 BM759416 BM771381

BM771216 BM771282 BM770933 CN481811 AI218199 CA430046 BM771298 BQ948761

highest scoring ESTs for MAFK:

AA404738 AF059194 AA443569 AA573340 AA978127 AI016038 AI057285 AI076447 AI147161 AI218199

Unigene Cluster for MAFK:

V-maf musculoaponeurotic fibrosarcoma oncogene homolog K (avian)

Hs.520612 [show with all ESTs]

Unigene Representative Sequence: NM_002360

GeneLoc Exon Structure

2 Ensembl transcripts including schematic representations:

ENST00000403150 ENST00000343242

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

MAFK expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for MAFK

¹ / ² / ³

7 probe-sets matching MAFK gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
33014_at²^{, 3}	U95-A	1	1.00	1.00	0.46	0.49	AF059194	1.00	1.00	1.00	1
49189_g_at²^{, 3}	U95-C	2	1.00	0.50	0.89	1.15	AA404738	1.00	1.00	1.00	1
49188_at²^{, 3}	U95-C	2	1.00	0.50	0.85	1.36	AA404738	1.00	1.00	1.00	1
206750_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_002360	0.60	1.00	0.82	1
226206_at²^{, 3}	U133-B	2	1.00	0.50	--	--	BG231691	0.80	1.00	0.91	1
206750_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
226206_at²	U133Plus2	2	1.00	0.50	--	--	--	--	--	--	--

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TGGGCCCGTG

SOURCE GeneReport for Unigene cluster: Hs.520612
Expression variation in blood from EXPOLDB for MAFK

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for MAFK gene from 5/9 species (see all 9 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	MAFK¹	--	v-maf musculoaponeurotic fibrosarcoma oncogene homolog more	92.01(n) 95.21(a)	489897 XM_547016.2 XP_547016.2
chimpanzee (Pan troglodytes)	MAFK¹	--	v-maf musculoaponeurotic fibrosarcoma oncogene homolog more	99.36(n) 99.36(a)	736345 XM_001136181.1 XP_001136181.1
cow (Bos taurus)	MAFK¹	--	v-maf musculoaponeurotic fibrosarcoma oncogene homolog more	90.89(n) 91.33(a)	618914 XM_871229.2 XP_876322.2
rat (Rattus norvegicus)	Mafk¹	--	v-maf musculoaponeurotic fibrosarcoma oncogene homolog more	91.45(n) 97.44(a)	246760 NM_145673.2 NP_663706.2
mouse (Mus musculus)	Mafk^{1, 5}	5 (79.80 cM)⁵	v-maf musculoaponeurotic fibrosarcoma oncogene family, more^{1, 5}	89.74(n)¹ 98.08(a)¹	17135¹ NM_010757.2¹ NP_034887.1¹ AK143654⁵ AK143717⁵ (see all 10)

About this table Species with no ortholog for MAFK

ENSEMBL Gene Tree for MAFK

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for MAFK gene

MAFF² ENSG00000218788² MAFG²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/55 NCBI SNPs in MAFK are shown (see all 55 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 33)

AB	SNP ID	Valid	Chr 7 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs7805230^1,2	A,C,F,H	1535456(+)	`CCGCGA/GAGATG`	1	--	ng5¹		4		EU EA WA	412
	rs3735656^1,2	A,C,F,H	1547447(+)	`CAGGAT/CTCAGG`	1	--	ut3¹ ese³		5		EA EU WA	1906
	rs3814477^1,2	A,C,F,H	1535944(+)	`AACCCT/CGGGCA`	1	--	ng5¹		1		EU	116
	rs10254597^1,2	A,C,H	1536619(+)	`TGTTTG/ATAGAG`	1	--	ng5¹ tfbs³		4		EU EA WA	410
--	rs7794842^1,2	A,C	1535311(+)	`cagagC/Tgagac`	1	--	ng5¹		0	--	--	--	--
--	rs3829898^1,2	A,C	1535737(+)	`CAAGTA/GGGGGG`	1	--	ng5¹ trp³		0	--	--	--	--
	rs12112155^1,2	H	1536254(+)	`CCACAG/AAGGCT`	1	--	ng5¹		4		EU EA WA	394
--	rs11972795^1,2	C	1535119(+)	`ctccaC/Gcctgg`	1	--	ng5¹		0	--	--	--	--
	rs10252127^1,2	A,C,F,H	1545247(+)	`GGTGGG/CCACCC`	1	--	int¹		4		EU EA WA	412
	rs6973328^1,2	A,C,H	1538386(+)	`GCCCTA/GTGCAG`	1	--	int¹		3		EU EA	282

About this table

HapMap Linkage Disequilibrium images for MAFK (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 600197

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/60 PubMed articles for MAFK gene (see all 60 ):

Structure and chromosome mapping of the human small maf-genes MAFG and MAFK. (PubMed id 9763667)^{1, 2, 3} Iwata T....Ito E. (1998)
Human small Maf proteins form heterodimers with CNC family transcription factors and recognize the NF-E2 motif. (PubMed id 9150357)^{1, 3, 4} Toki T.... Ito E. (1997)
The DNA sequence of human chromosome 7. (PubMed id 12853948)^{3, 4} Hillier L.W.... Wilson R.K. (2003)
Small maf (MafG and MafK) proteins negatively regulate antioxidant response element-mediated expression and antioxidant induction of the NAD(P)H:Quinone oxidoreductase1 gene. (PubMed id 11013233)^{1, 3} Dhakshinamoorthy S. and Jaiswal A.K. (2000)
Purification of the human NF-E2 complex: cDNA cloning of the hematopoietic cell-specific subunit and evidence for an associated partner. (PubMed id 8355703)^{1, 3} Ney P.A.... Neinhuis A.W. (1993)
Kinase-selective enrichment enables quantitative phosphoproteomics of the kinome across the cell cycle. (PubMed id 18691976)⁴ Daub H.... Mann M. (2008)
A quantitative atlas of mitotic phosphorylation. (PubMed id 18669648)⁴ Dephoure N.... Gygi S.P. (2008)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)³ Ota T....Sugano S. (2004)
Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)³ Scherer S.W....Tsui L.C. (2003)
Comprehensive identification of human bZIP interactions with coiled-coil arrays. (PubMed id 12805554)³ Newman J.R. and Keating A.E. (2003)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 7975	HGNC: 6782	AceView: MAFK	Ensembl:ENSG00000198517	euGenes: HUgn7975
ECgene: MAFK	H-InvDB: MAFK

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for MAFK	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for MAFK
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for MAFK:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for MAFK-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for MAFK		Antibodies for MAFK
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for MAFK		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

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Search Novus for antibodies for MAFK

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MAFK Gene

protein-coding GIFtS: 57

Aliases &
Descriptions
for MAFK

Summaries
for MAFK

Genomic Location
for MAFK

Proteins
for MAFK

Protein Domains/
Families
for MAFK

Gene Function
for MAFK

Pathways & Interactions
for MAFK

Drugs & Compounds
for MAFK

Transcripts
for MAFK

Expression
for MAFK

Orthologs
for MAFK

Paralogs
for MAFK

SNPs/Variants
for MAFK

Disorders & Mutations
for MAFK

Medical News
for MAFK

Publications
for MAFK

Search for MAFK

Genome Databases showing MAFK

Other Databases showing MAFK

Specialized Databases showing MAFK

Licensable Technologies
for MAFK

Services
for MAFK

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

MAFK Gene

protein-coding GIFtS: 57

Aliases & Descriptionsfor MAFK

Summariesfor MAFK

Genomic Locationfor MAFK

Proteinsfor MAFK

Protein Domains/Familiesfor MAFK

Gene Functionfor MAFK

Pathways & Interactionsfor MAFK

Drugs & Compoundsfor MAFK

Transcriptsfor MAFK

Expression for MAFK

Orthologsfor MAFK

Paralogsfor MAFK

SNPs/Variantsfor MAFK

Disorders & Mutationsfor MAFK

Medical Newsfor MAFK

Publicationsfor MAFK

Search for MAFK

Genome Databases showing MAFK

Other Databases showing MAFK

Specialized Databases showing MAFK

Licensable Technologiesfor MAFK

Servicesfor MAFK

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for MAFK

Summaries
for MAFK

Genomic Location
for MAFK

Proteins
for MAFK

Protein Domains/
Families
for MAFK

Gene Function
for MAFK

Pathways & Interactions
for MAFK

Drugs & Compounds
for MAFK

Transcripts
for MAFK

Expression
for MAFK

Orthologs
for MAFK

Paralogs
for MAFK

SNPs/Variants
for MAFK

Disorders & Mutations
for MAFK

Medical News
for MAFK

Publications
for MAFK

Licensable Technologies
for MAFK

Services
for MAFK