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Aliases for MAFIP Gene

Aliases for MAFIP Gene

  • MAFF Interacting Protein (Pseudogene) 2 3
  • Tektin-4 Like Protein PP5644 3 4
  • Tektin 4 Pseudogene 4 2 3
  • MIP 3 4
  • MAFF Interacting Protein 2
  • MaFF-Interacting Protein 3
  • TEKT4P4 3
  • Pp5644 3

External Ids for MAFIP Gene

Previous GeneCards Identifiers for MAFIP Gene

  • GC04M9U0054
  • GC00M6J0000
  • GC21M009910

Summaries for MAFIP Gene

Entrez Gene Summary for MAFIP Gene

  • This gene was originally thought to be a protein coding gene. However, the encoded protein sequence is highly similar to the C-terminal sequence of the tektin-4 protein, and the transcript sequences of this gene are highly similar to the TEKT4 pseudogenes, which are found on chromosomes 4, 21 and Y, respectively. Therefore, this gene is thought to be another pseudogene of the TEKT4 gene (GeneID:150483). Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2012]

GeneCards Summary for MAFIP Gene

MAFIP (MAFF Interacting Protein (Pseudogene)) is a Pseudogene. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Regulation of Water Balance by Renal Aquaporins.

UniProtKB/Swiss-Prot for MAFIP Gene

  • Acts as coactivator of MAFF transcriptional activity. Inhibits cell growth and colony-forming efficiency.

No data available for Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MAFIP Gene

Genomics for MAFIP Gene

Genomic Location for MAFIP Gene

53,589 bp from pter
115,071 bp from pter
61,483 bases
Minus strand

Genomic View for MAFIP Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
  • 4_GL000194.1 by Ensembl
  • 14 not on reference assembly by HGNC

RefSeq DNA sequence for MAFIP Gene

No data available for Regulatory Elements for MAFIP Gene

Proteins for MAFIP Gene

  • Protein details for MAFIP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    MaFF-interacting protein
    Protein Accession:
    Secondary Accessions:

    Protein attributes for MAFIP Gene

    124 amino acids
    Molecular mass:
    13947 Da
    Quaternary structure:
    • Interacts with MIS18A. Interacts (via its coiled-coil region) with MAFF.

neXtProt entry for MAFIP Gene

Proteomics data for MAFIP Gene at MOPED

Post-translational modifications for MAFIP Gene

No Post-translational modifications

Other Protein References for MAFIP Gene

ENSEMBL proteins:

No data available for DME Specific Peptides for MAFIP Gene

Domains for MAFIP Gene

Protein Domains for MAFIP Gene


Suggested Antigen Peptide Sequences for MAFIP Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the tektin family.
  • Belongs to the tektin family.
genes like me logo Genes that share domains with MAFIP: view

No data available for Gene Families for MAFIP Gene

Function for MAFIP Gene

Molecular function for MAFIP Gene

UniProtKB/Swiss-Prot Function:
Acts as coactivator of MAFF transcriptional activity. Inhibits cell growth and colony-forming efficiency.

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for MAFIP Gene

Localization for MAFIP Gene

Subcellular locations from UniProtKB/Swiss-Prot for MAFIP Gene

Cytoplasm. Nucleus, nucleolus. Note=Interaction with MAFF induces its translocation from the cytoplasm to the nucleolus.

Gene Ontology (GO) - Cellular Components for MAFIP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
GO:0005730 nucleolus IEA --
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with MAFIP: view

No data available for Subcellular locations from COMPARTMENTS for MAFIP Gene

Pathways for MAFIP Gene

genes like me logo Genes that share pathways with MAFIP: view

Pathways by source for MAFIP Gene

Interacting Proteins for MAFIP Gene

Gene Ontology (GO) - Biological Process for MAFIP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006351 transcription, DNA-templated IEA --
GO:0006355 regulation of transcription, DNA-templated IEA --
genes like me logo Genes that share ontologies with MAFIP: view

Transcripts for MAFIP Gene

mRNA/cDNA for MAFIP Gene

(1) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MAFIP Gene

No ASD Table

Relevant External Links for MAFIP Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MAFIP Gene

mRNA Expression by UniProt/SwissProt for MAFIP Gene

Tissue specificity: Strongly expressed in brain, kidney and ovary. Moderately expressed in liver, spleen, thymus, prostate, testis, small intestine and colon. Weakly expressed in heart, placenta, lung and leukocytes.

Primer Products

In Situ Assay Products

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression and Expression partners for MAFIP Gene

Orthologs for MAFIP Gene

Evolution for MAFIP Gene

Gene Tree for MAFIP (if available)
Gene Tree for MAFIP (if available)

No data available for Orthologs for MAFIP Gene

Paralogs for MAFIP Gene

No data available for Paralogs for MAFIP Gene

Variants for MAFIP Gene

Sequence variations from dbSNP and Humsavar for MAFIP Gene

SNP ID Clin Chr 14 pos Sequence Context AA Info Type MAF
rs3692 -- 1(+) ATGGC(A/G)GTGAC nc-transcript-variant
rs4864 -- 1(+) GAAGA(C/G)ACTGT nc-transcript-variant
rs365829 -- 1(+) CATTT(C/T)TGAAG intron-variant
rs366926 -- 1(+) GGGGA(C/T)TCAGG intron-variant, downstream-variant-500B
rs382931 -- 1(-) CCCCA(C/T)GTCAT intron-variant

Relevant External Links for MAFIP Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MAFIP Gene

Disorders for MAFIP Gene

No disorders were found for MAFIP Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for MAFIP Gene

Publications for MAFIP Gene

  1. PP5644 interacts with phosphatidylinositol-4-phosphate adaptor protein-1 associated protein-1. (PMID: 15881666) Ye X.-X. … Gu J.-R. (Mol. Cell. Biochem. 2005) 2 3 4
  2. The novel human gene MIP functions as a co-activator of hMafF. (PMID: 16549056) Ye X. … Lu H. (Arch. Biochem. Biophys. 2006) 2 3 4
  3. Large-scale cDNA transfection screening for genes related to cancer development and progression. (PMID: 15498874) Wan D. … Gu J. (Proc. Natl. Acad. Sci. U.S.A. 2004) 3 4
  4. Establish a recombinant yeast detection system to study the effect of MIP on transactivation function of hMafF in US2-driven gene transcription. (PMID: 19723544) Ye X. … Chen D. (J. Microbiol. Methods 2009) 3
  5. Finding a novel interacting protein of the hepatic carcinoma related gene MIP: NF-I_B essential modulator (NEMO). (PMID: 21109981) Ye X. … Chen D. (Oncol. Rep. 2011) 3

Products for MAFIP Gene

Sources for MAFIP Gene

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