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MAFA Gene

protein-coding GIFtS: 53

GC08M144582

v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
RIPE3B1 ^⁵
RIPE3b1 ^¹, ²
hMafA ^¹, ²

Descriptions
Pancreatic beta-cell-specific transcriptional activator ^³
Transcription factor RIPE3b1 ^³
V-maf musculoaponeurotic fibrosarcoma oncogene homolog A ^², ³
v-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian) ^²

External Ids
HGNC: 23145¹
Entrez Gene: 389692²
UniProtKB: Q8NHW3³
Ensembl: ENSG00000182759⁷

Search outside databases for aliases for MAFA gene

Previous GC identifers: GC08U900345 GC08M144617

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for MAFA:

MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates

pancreatic beta cell-specific expression of the insulin gene (INS; MIM 176730) (Olbrot et al.,

2002 [PubMed 12011435]).[supplied by OMIM]

UniProtKB/Swiss-Prot: MAFA_HUMAN, Q8NHW3

Function: Acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b

and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1.

Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic

activity. Involved either as an oncogene or as a tumor suppressor, depending on the cell context

Gene Wiki entry for MAFA

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the MAFA gene

Entrez Gene cytogenetic band: 8q24.3 Ensembl cytogenetic band: 8q24.3 HGNC cytogenetic band: 8q24.3

MAFA Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 8 GeneLoc Exon Structure

GeneLoc location for GC08M144582: (about GC identifiers)

Start:	144,582,658 bp from pter
End:	144,583,719 bp from pter
Size:	1,062 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000008.9 NT_023684.17

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: MAFA_HUMAN, Q8NHW3 (See protein sequence)

Recommended Name: Transcription factor MafA

Size: 352 amino acids; 36845 Da

Subunit: Binds DNA as a homodimer (Probable). Interacts with NEUROD1, PCAF and PDX1

Subcellular location: Nucleus. Note=Detected in nuclei of pancreas islet beta cells (By similarity)

Post-translational modifications:

Ubiquitinated, leading to its degradation by the proteasome¹

Ser-14 and Ser-65 appear to be the major phosphorylation sites. Phosphorylated by MAPK13 on serine

and threonine residues (Probable). Phosphorylation by GSK3 requires prior phosphorylation of

Ser-65 by another kinase. Phosphorylation proceeds then from Ser-61 to Thr-57, Thr-53 and Ser-49.

GSK3-mediated phosphorylation increases its transcriptional activity through the recruitment of

the coactivator PCAF, is required for its transforming activity and leads to its degradation

through an ubiquitin/proteasome-dependent pathway¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_963883.2

ENSEMBL proteins:

ENSP00000328364

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (MafA, MAFA)
	Human Recombinant Proteins from Abnova (MAFA)

OriGene Purified Recombinant Human Protein: MAFA

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IDA	12368292

About this table

Antibodies for MAFA:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for MAFA
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (MafA, MAFA), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (MAFA)
	Novus Biologicals Antibodies for MAFA

Assays for MAFA:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q8NHW3

ProtoNet protein and cluster: Q8NHW3

2 Blocks protein families:

IPB004826 Maf transcription factor

IPB013592 Maf transcription factor

UniProtKB/Swiss-Prot: MAFA_HUMAN, Q8NHW3

Similarity: Belongs to the bZIP family. Maf subfamily

Similarity: Contains 1 bZIP domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MAFA)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (MAFA)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_201589

Applied Biosystems Silencer® siRNAs for MAFA

Sigma-Aldrich siRNA for MAFA

Sigma-Aldrich shRNA for MAFA

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_201589
Myc/DDK tagged cDNA clone in CMV expression vector: NM_201589
untagged cDNA clone in CMV expression vector: NM_201589

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_201589

UniProtKB/Swiss-Prot: MAFA_HUMAN, Q8NHW3

Function: Acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b

and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1.

Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic

activity. Involved either as an oncogene or as a tumor suppressor, depending on the cell context

Induction: Up-regulated by glucose

5 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Mafa):

digestive/alimentary

endocrine/exocrine gland

growth/size

homeostasis/metabolism

renal/urinary system

5 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	transcription factor activity	TAS	12368292
GO:0016563	transcription activator activity	IEA	--
GO:0042803	protein homodimerization activity	TAS	12368292
GO:0043565	sequence-specific DNA binding	IEA	--
GO:0046982	protein heterodimerization activity	NAS	12368292

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

1 Sigma-Aldrich "Your Favorite Gene" Pathway for MAFA (Your Favorite Gene powered by Ingenuity)

Type II Diabetes Mellitus Signaling

GeneDecks MAFA for the pathways selected above

About GeneDecksing

Gene Network Central^TM Interacting Genes and Proteins Network for MAFA

5/9 Interacting proteins for MAFA (ENSP00000328364³) via UniProtKB, MINT, and/or STRING (see all 9 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
PDX1	ENSP00000370421³	STRING (score=.993)
INS	ENSP00000370731³	STRING (score=.975)
NEUROD1	ENSP00000295108³	STRING (score=.88)
IGF1R	ENSP00000268035³	STRING (score=.817)
IGF1	ENSP00000302665³	STRING (score=.814)

About this table

5 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006355	regulation of transcription, DNA-dependent	TAS	12368292
GO:0007263	nitric oxide mediated signal transduction	IDA	17941991
GO:0009749	response to glucose stimulus	IDA	12368292
GO:0030073	insulin secretion	IDA	17941991
GO:0045944	positive regulation of transcription from RNA polymerase II promoter	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for MAFA
1 Novoseek chemical compound relationship for MAFA gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
glucose	44.41	39	8613527 (4), 17682063 (4), 12368292 (3), 8289826 (2) (see all 9)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MAFA)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (MAFA)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_201589

Sigma-Aldrich siRNA for MAFA

Sigma-Aldrich shRNA for MAFA

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_201589

REFSEQ mRNAs for MAFA gene:

NM_201589.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_201589

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_201589
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_201589
                                 untagged cDNA clone in CMV expression vector: NM_201589

1 DOTS entry:

DT.97838907

1 AceView cDNA sequence:

AI761030

highest scoring ESTs for MAFA:

BE676631 BM052845 BM127748 AA452554 AI761030 AI805256 BE621358 BM052615 NM_201589 BM126790

Unigene Cluster for MAFA:

V-maf musculoaponeurotic fibrosarcoma oncogene homolog A (avian)

Hs.670866 [show with all ESTs]

Unigene Representative Sequence: NM_201589

GeneLoc Exon Structure

1 Ensembl transcript including schematic representation:

ENST00000333480

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

MAFA expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for MAFA

¹ / ³ Data from (Publications) and GNF BioGPS
About these images

About these images

CGAP SAGE TAG: TCGGTGCGCG

SOURCE GeneReport for Unigene cluster: Hs.670866

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for MAFA gene from 3 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
rat (Rattus norvegicus)	Mafa¹	--	v-maf musculoaponeurotic fibrosarcoma oncogene homolog more	90.88(n) 94.3(a)	366949 XM_345846.2 XP_345847.2
mouse (Mus musculus)	Mafa^{1, 5}	15⁵	v-maf musculoaponeurotic fibrosarcoma oncogene family, more^{1, 5}	91.93(n)¹ 95.16(a)¹	378435¹ NM_194350.1¹ NP_919331.1¹ AB086961⁵ BC156190⁵ (see all 6)
zebrafish (Danio rerio)	mafl²	--	v-maf musculoaponeurotic fibrosarcoma (avian) oncogene more	82.63(n)	114468 AB006324.2

About this table Species with no ortholog for MAFA

ENSEMBL Gene Tree for MAFA

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for MAFA gene

NRL² MAF² MAFB²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/21 NCBI SNPs in MAFA are shown (see all 21 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 57)

AB	SNP ID	Valid	Chr 8 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs1994448^1,2	A,C,F,H	144585526(+)	`GTCCCA/GGAGGG`	1	--	ng3¹		3		EA WA	294
--	rs2054844^1,2	A,C	144584725(+)	`CCGGCG/TTGTGG`	1	--	ng3¹		0	--	--	--	--
--	rs7386685^1,2	C	144582532(+)	`TGGCAC/GCGGGG`	1	--	ng5¹		0	--	--	--	--
--	rs7830682^1,2	C	144584346(+)	`TCCCAC/GACCCG`	1	--	ng3¹		0	--	--	--	--
	rs11774314^1,2	H	144585259(+)	`CACGGT/CGCCGC`	1	--	ng3¹		4		EU EA WA	412
--	rs4874115^1,2	--	144582428(+)	`TTAGAA/TATCAC`	1	--	ng5¹		0	--	--	--	--
	rs35541709^1,2	--	144585257(+)	`GTCACA/GGCGCC`	1	--	ng3¹		0	--	--	--	--
--	rs62521874^1,2	--	144582681(+)	`CGTGCA/CCTTGG`	1	G/C	mis¹		0	--	--	--	--
--	rs59176601^1,2	--	144583124(+)	`GGTGG-/TGGGCGGC`	2	H/ H/P	fra¹		0	--	--	--	--
--	rs34540942^1,2	--	144585160(+)	`AGCAA-/TTTAAA`	1	--	ng3¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for MAFA (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 610303

2 Novoseek disease relationships for MAFA gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
fibrosarcoma	58.66	4	18778246 (1), 17131142 (1), 17149590 (1), 18851698 (1)
insulinoma	47.28	1	14765989 (1)

About this table

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/38 PubMed articles for MAFA gene (see all 38 ):

MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene. (PubMed id 12368292)^{1, 3, 4} Kataoka K.... Handa H. (2002)
Synergistic activation of the insulin gene promoter by the beta-cell enriched transcription factors MafA, Beta2, and Pdx1. (PubMed id 15993959)^{1, 3, 4} Aramata S....Kataoka K. (2005)
GSK-3-mediated phosphorylation enhances Maf-transforming activity. (PubMed id 18042454)^{3, 4} Rocques N....Pouponnot C. (2007)
The islet beta cell-enriched MafA activator is a key regulator of insulin gene transcription. (PubMed id 15665000)^{3, 4} Zhao L....Stein R. (2005)
Identification of beta-cell-specific insulin gene transcription factor RIPE3b1 as mammalian MafA. (PubMed id 12011435)^{3, 4} Olbrot M.... Sharma A. (2002)
Phosphorylation of MafA is essential for its transcriptional and biological properties. (PubMed id 11416124)^{3, 4} Benkhelifa S....Felder-Schmittbuhl M.P. (2001)
FoxA2, Nkx2.2, and PDX-1 regulate islet beta-cell-specific mafA expression through conserved sequences located between base pairs -8118 and -7750 upstream from the transcription start site. (PubMed id 16847327)^{1, 3} Raum J.C....Stein R. (2006)
PDX-1 functions as a master factor in the pancreas. (PubMed id 18508668)^{1, 3} Kaneto H....Matsuhisa M. (2008)
MafA and MafB regulate Pdx1 transcription through the Area II control region in pancreatic beta cells. (PubMed id 18522939)³ Vanhoose A.M....Stein R. (2008)
A new MAFia in cancer. (PubMed id 18701893)³ Eychene A....Pouponnot C. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 389692	HGNC: 23145	AceView: MAFA	Ensembl:ENSG00000182759	euGenes: HUgn389692
ECgene: MAFA	H-InvDB: MAFA

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for MAFA	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for MAFA
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for MAFA:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for MAFA-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for MAFA		Antibodies for MAFA
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for MAFA		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (MAFA)
	Antibodies (MAFA)
	Chimera RNAi (MAFA)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (MafA, MAFA)
	Antibodies (MafA, MAFA)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for MAFA

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for MAFA

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MAFA Gene

protein-coding GIFtS: 53

Aliases &
Descriptions
for MAFA

Summaries
for MAFA

Genomic Location
for MAFA

Proteins
for MAFA

Protein Domains/
Families
for MAFA

Gene Function
for MAFA

Pathways & Interactions
for MAFA

Drugs & Compounds
for MAFA

Transcripts
for MAFA

Expression
for MAFA

Orthologs
for MAFA

Paralogs
for MAFA

SNPs/Variants
for MAFA

Disorders & Mutations
for MAFA

Medical News
for MAFA

Publications
for MAFA

Search for MAFA

Genome Databases showing MAFA

Other Databases showing MAFA

Specialized Databases showing MAFA

Licensable Technologies
for MAFA

Services
for MAFA

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

MAFA Gene

protein-coding GIFtS: 53

Aliases & Descriptionsfor MAFA

Summariesfor MAFA

Genomic Locationfor MAFA

Proteinsfor MAFA

Protein Domains/Familiesfor MAFA

Gene Functionfor MAFA

Pathways & Interactionsfor MAFA

Drugs & Compoundsfor MAFA

Transcriptsfor MAFA

Expression for MAFA

Orthologsfor MAFA

Paralogsfor MAFA

SNPs/Variantsfor MAFA

Disorders & Mutationsfor MAFA

Medical Newsfor MAFA

Publicationsfor MAFA

Search for MAFA

Genome Databases showing MAFA

Other Databases showing MAFA

Specialized Databases showing MAFA

Licensable Technologiesfor MAFA

Servicesfor MAFA

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for MAFA

Summaries
for MAFA

Genomic Location
for MAFA

Proteins
for MAFA

Protein Domains/
Families
for MAFA

Gene Function
for MAFA

Pathways & Interactions
for MAFA

Drugs & Compounds
for MAFA

Transcripts
for MAFA

Expression
for MAFA

Orthologs
for MAFA

Paralogs
for MAFA

SNPs/Variants
for MAFA

Disorders & Mutations
for MAFA

Medical News
for MAFA

Publications
for MAFA

Licensable Technologies
for MAFA

Services
for MAFA