Aliases for MAFA Gene
Aliases for MAFA Gene
- MAF BZIP Transcription Factor A 2 3 5
- V-Maf Avian Musculoaponeurotic Fibrosarcoma Oncogene Homolog A 2 3
- Pancreatic Beta-Cell-Specific Transcriptional Activator 3 4
- Transcription Factor RIPE3b1 3 4
- V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog A 4
- Transcription Factor MafA 3
- RIPE3b1 3
- HMafA 3
External Ids for MAFA Gene
- HGNC: 23145
- Entrez Gene: 389692
- Ensembl: ENSG00000182759
- OMIM: 610303
- UniProtKB: Q8NHW3
Previous GeneCards Identifiers for MAFA Gene
- GC08U900345
- GC08M144617
- GC08M144582
- GC08M144511
- GC08M139764
Summaries for MAFA Gene
-
MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene (INS; MIM 176730) (Olbrot et al., 2002 [PubMed 12011435]).[supplied by OMIM, Mar 2008]
GeneCards Summary for MAFA Gene
MAFA (MAF BZIP Transcription Factor A) is a Protein Coding gene. Diseases associated with MAFA include Fibrosarcoma and Monogenic Diabetes. Among its related pathways are Type II diabetes mellitus and Tacrolimus/Cyclosporine Pathway, Pharmacodynamics. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and sequence-specific DNA binding. An important paralog of this gene is MAF.
UniProtKB/Swiss-Prot for MAFA Gene
-
Acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Involved either as an oncogene or as a tumor suppressor, depending on the cell context.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MAFA Gene
Genomics for MAFA Gene
Regulatory Elements for MAFA Gene
Enhancers for MAFA Gene
- Elite enhancer and/or Elite enhancer-gene association
Download GeneHancer data dump
Enhancers around MAFA on UCSC Golden Path with GeneCards custom track
Regulatory Element Products
Genomic Location for MAFA Gene
- Chromosome:
- 8
- Start:
- 143,419,182 bp from pter
- End:
- 143,430,432 bp from pter
- Size:
- 11,251 bases
- Orientation:
- Minus strand
Genomic View for MAFA Gene
Genes around MAFA on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 8q24.3 by Ensembl
- 8q24.3 by Entrez Gene
- 8q24.3 by HGNC
MAFA Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MAFA Gene
Proteins for MAFA Gene
-
Protein details for MAFA Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8NHW3-MAFA_HUMAN
- Recommended name:
- Transcription factor MafA
- Protein Accession:
- Q8NHW3
Protein attributes for MAFA Gene
- Size:
- 353 amino acids
- Molecular mass:
- 36982 Da
- Quaternary structure:
-
- Binds DNA as a homodimer. Interacts with NEUROD1, PCAF and PDX1.
Protein Expression for MAFA Gene
Post-translational modifications for MAFA Gene
- Ser-14 and Ser-65 appear to be the major phosphorylation sites. Phosphorylated by MAPK13 on serine and threonine residues (Probable). Phosphorylation by GSK3 requires prior phosphorylation of Ser-65 by another kinase. Phosphorylation proceeds then from Ser-61 to Thr-57, Thr-53 and Ser-49. GSK3-mediated phosphorylation increases its transcriptional activity through the recruitment of the coactivator PCAF, is required for its transforming activity and leads to its degradation through a ubiquitin/proteasome-dependent pathway.
- Ubiquitinated, leading to its degradation by the proteasome.
- Modification sites at PhosphoSitePlus
- Modification sites at neXtProt
Other Protein References for MAFA Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for MAFA
-
Custom Antibody ServicesOriGene Antibodies for MAFA
- Novus Biologicals Antibodies for MAFA
- Invitrogen Antibodies for MAFA
- antibodies-online Antibodies for MAFA: See all 52
- Search GeneTex for Antibodies for MAFA
-
Santa Cruz Biotechnology (SCBT) Antibodies for MAFA
Protein Products
-
OriGene Purified Proteins for MAFA
- Search Origene for MassSpec and Protein Over-expression Lysates for MAFA
- Origene Custom Protein Services for MAFA
- antibodies-online Proteins for MAFA: See all 7
- Search antibodies-online for peptides
- Search GeneTex for Proteins for MAFA
Assay Products
- antibodies-online Kits for MAFA: See all 10
No data available for DME Specific Peptides for MAFA Gene
Domains & Families for MAFA Gene
Gene Families for MAFA Gene
Protein Domains for MAFA Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for MAFA Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q8NHW3- Family:
-
- Belongs to the bZIP family. Maf subfamily.
Function for MAFA Gene
Molecular function for MAFA Gene
- UniProtKB/Swiss-Prot Function:
- Acts as a transcriptional factor. Specifically binds the insulin enhancer element RIPE3b and activates insulin gene expression. Cooperates synergistically with NEUROD1 and PDX1. Phosphorylation by GSK3 increases its transcriptional activity and is required for its oncogenic activity. Involved either as an oncogene or as a tumor suppressor, depending on the cell context.
- UniProtKB/Swiss-Prot Induction:
- Up-regulated by glucose.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding | IEA | -- |
| GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding | IEA | -- |
| GO:0003677 | DNA binding | IDA | 12368292 |
| GO:0003700 | transcription factor activity, sequence-specific DNA binding | TAS | 12368292 |
| GO:0042803 | protein homodimerization activity | TAS | 12368292 |
Phenotypes for MAFA Gene
- MGI mutant phenotypes for MAFA:
- inferred from 4 alleles
- GenomeRNAi human phenotypes for MAFA:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MAFA
-
-
ViGene Biosciences lentiviral particle packaged cDNA for MAFA gene
-
ViGene Biosciences ready-to-package AAV shRNAs for MAFA gene
- Search ViGene Biosciences for MAFA
CRISPR Products
-
OriGene CRISPR knockouts for MAFA
-
Santa Cruz Biotechnology (SCBT) CRISPR for MAFA
- GenScript: Design CRISPR guide RNA sequences for MAFA
Targeted motifs for MAFA Gene
HOMER Transcription Factor Regulatory Elements motif MAFA
- Consensus sequence: TGCTGACTCA Submotif: canonical Cell Type: Islet GEO ID: GSE30298
miRNA Products
- Search ViGene Biosciences for MAFA
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for MAFA
- Browse OriGene Inhibitory RNA Products For MAFA
-
ViGene Biosciences ready-to-package AAV shRNAs for MAFA gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for MAFA
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MAFA
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Cell Line Products
-
Horizon Cell Lines for MAFA
-
ViGene Biosciences adenoviral particle packaged cDNA for MAFA gene
-
ViGene Biosciences lentiviral particle packaged cDNA for MAFA gene
-
ViGene Biosciences ready-to-package AAV shRNAs for MAFA gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA and Transcription Factor Targets for MAFA Gene
Localization for MAFA Gene
Subcellular locations from UniProtKB/Swiss-Prot for MAFA Gene
- Nucleus. Note=Detected in nuclei of pancreas islet beta cells. {ECO:0000250}.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytosol | 2 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005634 | nucleus | IDA | 12368292 |
Pathways & Interactions for MAFA Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Regulation of beta-cell development | ||
| 2 | Type II diabetes mellitus | ||
| 3 | Tacrolimus/Cyclosporine Pathway, Pharmacodynamics | ||
| 4 | Developmental Biology | ||
Pathways by source for MAFA Gene
1 BioSystems pathway for MAFA Gene
3 Reactome pathways for MAFA Gene
2 PharmGKB pathways for MAFA Gene
2 KEGG pathways for MAFA Gene
Interacting Proteins for MAFA Gene
SIGNOR curated interactions for MAFA Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006351 | transcription, DNA-templated | IEA | -- |
| GO:0006355 | regulation of transcription, DNA-templated | TAS | 12368292 |
| GO:0006366 | transcription from RNA polymerase II promoter | IEA | -- |
| GO:0007263 | nitric oxide mediated signal transduction | IDA | 17941991 |
| GO:0009749 | response to glucose | IDA | 12368292 |
Transcripts for MAFA Gene
mRNA/cDNA for MAFA Gene
- (1) REFSEQ mRNAs :
- (0) Additional mRNA sequences :
- -
- (1) Selected AceView cDNA sequences:
- (2) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for MAFA Gene
CRISPR Products
-
OriGene CRISPR knockouts for MAFA
-
Santa Cruz Biotechnology (SCBT) CRISPR for MAFA
- GenScript: Design CRISPR guide RNA sequences for MAFA
miRNA Products
- Search ViGene Biosciences for MAFA
Inhibitory RNA Products
- Origene RNAi, siRNA, and shRNA products in human, mouse, rat for MAFA
- Browse OriGene Inhibitory RNA Products For MAFA
-
ViGene Biosciences ready-to-package AAV shRNAs for MAFA gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for MAFA
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MAFA
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Flow Cytometry Products
Expression for MAFA Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Pancreas (Endocrine System)
- Immature Beta Progenitor Cells Dorsal Pancreatic Bud
- Immature Beta Progenitor Cells Ventral Pancreatic Bud
- Mature Beta Cells Islets of Langerhans
- Beta-like cells(Zhang D et. al. 2009)
-
Skeletal Muscle (Muscoskeletal System)
mRNA differential expression in normal tissues according to GTEx for MAFA Gene
This gene is overexpressed in Muscle - Skeletal (x30.3) and Testis (x6.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for MAFA Gene
NURSA nuclear receptor signaling pathways regulating expression of MAFA Gene:
MAFASOURCE GeneReport for Unigene cluster for MAFA Gene:
Hs.521914Evidence on tissue expression from TISSUES for MAFA Gene
- Pancreas(3.1)
Primer Products
-
OriGene qPCR primer pairs for MAFA
No data available for Protein differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MAFA Gene
Orthologs for MAFA Gene
This gene was present in the common ancestor of animals.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | -- 35 |
|
ManyToMany | |
| dog (Canis familiaris) |
Mammalia | MAFA 34 35 |
|
||
| cow (Bos Taurus) |
Mammalia | MAFA 34 35 |
|
||
| mouse (Mus musculus) |
Mammalia | Mafa 34 16 35 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Mafa 34 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | MAFA 35 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | MAFA 34 35 |
|
||
| tropical clawed frog (Silurana tropicalis) |
Amphibia | mafa 34 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | mafa 34 35 |
|
||
| mafl 34 |
|
||||
| fruit fly (Drosophila melanogaster) |
Insecta | tj 35 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | maf-1 35 |
|
OneToMany | |
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 35 |
|
ManyToMany |
- Species where no ortholog for MAFA was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- lizard (Anolis carolinensis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- platypus (Ornithorhynchus anatinus)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
Paralogs for MAFA Gene
Variants for MAFA Gene
| SNP ID | Clin | Chr 08 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs1000236441 | -- | 143,430,275(+) | GGCAG(A/G)CGGTG | reference, synonymous-codon | |
| rs1000880922 | -- | 143,431,486(+) | GGGCG(A/G)GGCCC | upstream-variant-2KB | |
| rs1000936167 | -- | 143,431,289(+) | GGCTC(A/T)GACGC | upstream-variant-2KB | |
| rs1000975846 | -- | 143,428,747(+) | GGAGG(A/G)GGCAG | utr-variant-3-prime | |
| rs1001598046 | -- | 143,429,203(+) | CCCGC(A/G)CCCGC | utr-variant-3-prime |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv1199n67 | CNV | gain | 20364138 |
| esv2668424 | CNV | deletion | 23128226 |
| esv3619107 | CNV | gain | 21293372 |
| nsv1112971 | CNV | deletion | 24896259 |
| nsv1144240 | CNV | deletion | 24896259 |
| nsv470247 | CNV | loss | 18288195 |
| nsv612768 | CNV | loss | 21841781 |
| nsv612769 | CNV | loss | 21841781 |
| nsv824765 | CNV | gain | 20364138 |
| nsv950012 | CNV | deletion | 24416366 |
Gene Damage Index Score:
4.03;
60.44% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for MAFA Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- MAFA
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MAFA Gene
Disorders for MAFA Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| fibrosarcoma |
|
|
| monogenic diabetes |
|
|
Search MAFA in MalaCards
View complete list of genes associated with diseases
Relevant External Links for MAFA
No data available for UniProtKB/Swiss-Prot and Genatlas for MAFA Gene
Publications for MAFA Gene
- Mutations in MAFA and IAPP are not a common cause of monogenic diabetes. (PMID: 19573128) Garin I. … Perez de Nanclares G. (Diabet. Med. 2009) 3 22 46 64
- Synergistic activation of the insulin gene promoter by the beta-cell enriched transcription factors MafA, Beta2, and Pdx1. (PMID: 15993959) Aramata S. … Kataoka K. (Biochim. Biophys. Acta 2005) 3 4 22 64
- MafA is a glucose-regulated and pancreatic beta-cell-specific transcriptional activator for the insulin gene. (PMID: 12368292) Kataoka K. … Handa H. (J. Biol. Chem. 2002) 3 4 22 64
- Role of MafA in pancreatic beta-cells. (PMID: 19393272) Kaneto H. … Matsuhisa M. (Adv. Drug Deliv. Rev. 2009) 3 22 64
- PDX-1 functions as a master factor in the pancreas. (PMID: 18508668) Kaneto H. … Matsuhisa M. (Front. Biosci. 2008) 3 22 64
Products for MAFA Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
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- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
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- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
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- Custom Antibody ServicesOriGene Antibodies for MAFA
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for MAFA
- Search Origene for MassSpec and Protein Over-expression Lysates for MAFA
- Origene Custom Protein Services for MAFA
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- OriGene qPCR primer pairs for MAFA
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- GenScript: Next-day shipping cDNA ORF clone for MAFA in any vector
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- GenScript Custom overexpressing Cell Line Services for MAFA
- GenScript: Design CRISPR guide RNA sequences for MAFA
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
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- Sino Biological Transfection Reagents
- Novus Biologicals Antibodies for MAFA
- Novus Biologicals proteins and lysates for MAFA
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- antibodies-online Antibodies for MAFA: See all 52
- antibodies-online Kits for MAFA: See all 10
- antibodies-online Proteins for MAFA: See all 7
- Search antibodies-online for peptides
- Search GeneTex for Antibodies for MAFA
- Search GeneTex for Proteins for MAFA
- ViGene Biosciences adenoviral particle packaged cDNA for MAFA gene
- ViGene Biosciences lentiviral particle packaged cDNA for MAFA gene
- ViGene Biosciences ready-to-package AAV shRNAs for MAFA gene
- Search ViGene Biosciences for MAFA
- Santa Cruz Biotechnology (SCBT) Antibodies for MAFA
- Search Santa Cruz Biotechnology (SCBT) for MAFA siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for MAFA
- Horizon Cell Lines for MAFA
- Cyagen custom Knockout/knockin (KOKI) mouse models for MAFA
- VectorBuilder custom plasmid, inducible vectors for MAFA
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MAFA
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
Sources for MAFA Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) RNAdb
- (29) ASD
- (30) ECgene
- (31) GeneAnnot
- (32) CGAP SAGE
- (33) SOURCE
- (34) HomoloGene
- (35) PanEnsembl
- (36) euGenes
- (37) SGD
- (38) FlyBase
- (39) WormBase
- (40) Pseudogene
- (41) DGV
- (42) dbSNP
- (43) GenAtlas
- (44) GeneTests
- (45) HGMD
- (46) GAD
- (47) LSDB
- (48) BGMUT
- (49) HuGE
- (50) eBioscience
- (51) Atlas
- (52) Cell Signaling Technology
- (53) GenBank
- (54) H-invDB
- (55) HORDE
- (56) HUGE
- (57) IMGT
- (58) Leiden
- (59) MILLIPORE
- (60) miRBase
- (61) DME
- (62) NCBI
- (63) OriGene
- (64) PubMed
- (65) R&D Systems
- (66) TGDB
- (67) Tocris
- (68) Abcam
- (69) Novus
- (70) ProSpec
- (71) Sino Biological
- (72) GenScript
- (73) Qiagen
- (74) Cloud-Clone Corp.
- (75) Enzo Life Sciences
- (76) OCA
- (77) Proteopedia
- (78) MOPED
- (79) SPIRE
- (80) neXtProt
- (81) Reactome
- (82) GeneGo (Thomson Reuters)
- (83) fRNAdb
- (84) DISEASES
- (85) SIMAP
- (86) GenomeRNAi
- (87) LifeMap
- (88) miRTarBase
- (89) MalaCards
- (90) Invitrogen
- (91) BitterDB
- (92) Vector BioLabs
- (93) ESI-BIO
- (94) RefSeq
- (95) BioSystems
- (96) MaxQB
- (97) IUPHAR
- (98) BioGPS
- (99) Illumina
- (100) COMPARTMENTS
- (101) HOMER
- (102) PaxDb
- (103) ApexBio
- (104) Addgene
- (105) antibodies-online
- (106) CYP
- (107) NONCODE
- (108) SwitchGear Genomics
- (109) TreeFam
- (110) PathCards
- (111) GeneReviews
- (112) GeneTex
- (113) Taconic Biosciences
- (114) GTEx
- (115) ProteomicsDB
- (116) SCBT
- (117) DGIdb
- (118) ClinicalTrials
- (119) FDA Approved Drugs
- (120) RVIS
- (121) SIGNOR
- (122) diseasecard
- (123) NIH Rare Diseases
- (124) Orphanet
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- (126) GTR
- (127) Disease Ontology
- (128) Genetics Home Reference
- (129) MeSH
- (130) MedlinePlus
- (131) CDC
- (132) NINDS
- (133) NCBI Bookshelf
- (134) ClinVar
- (135) Gene Damage Index
- (136) ViGene Biosciences
- (137) HPO
- (138) UDN
- (139) VISTA
- (140) FANTOM5
- (141) ENCODE
- (142) ProSci
- (143) Horizon
- (144) NURSA
- (145) IID
- (146) Cyagen
- (147) VectorBuilder
- (148) SNPedia
- (149) BRCA Exchange
- (150) St John's Lab
- (151) CIViC
- (152) ProteoGenix
- (153) dbSUPER
- (154) TISSUES
- (155) Gene ORGANizer