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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

MAEL Gene

protein-coding GIFtS: 47
GCID: GC01P166958

maelstrom spermatogenic transposon silencer

(Previous name: maelstrom homolog (Drosophila) )

Explore 5 diseases affiliated with
MAEL via

MalaCards

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Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Maelstrom Spermatogenic Transposon Silencer¹ ²		RP11-102C16.1²
CT128¹ ²		Cancer/Testis Antigen 128²
SPATA35¹ ²		Maelstrom Homolog²
FLJ14904¹		Protein Maelstrom Homolog²
Maelstrom Homolog (Drosophila)¹		Spermatogenesis Associated 35²

External Ids:	HGNC: 25929¹	Entrez Gene: 84944²	Ensembl: ENSG00000143194⁷	OMIM: 611368⁵	UniProtKB: Q96JY0³

Export aliases for MAEL gene to outside databases

Previous GC identifers: GC01P163691 GC01P165224 GC01P138205

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: MAEL_HUMAN, Q96JY0

Function: Plays a central role during spermatogenesis by repressing transposable elements and prevent their

mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the

repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and

govern the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a

participation in the secondary piRNAs metabolic process. Required for localization of germ-cell factors to the meiotic

nuage (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_004487.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the MAEL gene promoter:
Pbx1a FAC1 E2F E2F-1 CBF-A CBF-B CP1A RSRFC4 CBF(2)
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: MAEL promoter sequence

Search SABiosciences Chromatin IP Primers for MAEL

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAEL

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q24.1 Ensembl cytogenetic band: 1q24.1 HGNC cytogenetic band: 1q24.1

MAEL Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MAEL gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01P166958: view genomic region (about GC identifiers)

Start:	166,958,346 bp from pter	End:	166,991,451 bp from pter
Size:	33,106 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: MAEL_HUMAN, Q96JY0 (See protein sequence)

Recommended Name: Protein maelstrom homolog

Size: 434 amino acids; 49219 Da

Subunit: Interacts with SMARCB1, SIN3B and DDX4. Interacts with piRNA-associated proteins TDRD1, PIWIL1 and PIWIL2 (By

similarity)

Subcellular location: Cytoplasm. Nucleus. Note=Component of the meiotic nuage, also named P granule, a

germ-cell-specific organelle required to repress transposon during meiosis. Specifically localizes to piP-bodies, a

subset of the nuage which contains secondary piRNAs (By similarity)

Sequence caution: Sequence=CAH69955.1; Type=Erroneous gene model prediction;

1 PDB 3D structure from and Proteopedia for MAEL:

2CTO (3D)

Secondary accessions: B4DY43 Q49AP9 Q5VZP8 Q9UIW6

Alternative splicing: 3 isoforms: Q96JY0-1 Q96JY0-2 Q96JY0-3 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MAEL: NX_Q96JY0

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q96JY0

MAEL Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_116247.1

ENSEMBL proteins:

ENSP00000356846 ENSP00000402143 ENSP00000356844

Human Recombinant Protein Products:

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	Novus Biologicals MAEL Protein Novus Biologicals MAEL Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for MAEL

Gene Ontology (GO): 5/12 cellular component terms (GO ID links to tree view) (see all 12): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000785	chromatin	IEA	--
GO:0001741	XY body	IEA	--
GO:0005634	nucleus	ISS	--
GO:0005730	NOT nucleolus	IDA	--
GO:0005737	cytoplasm	ISS	--

MAEL for ontologies About GeneDecksing

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	Uscn ELISAs and CLIAs for MAEL

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

MAEL for domains About GeneDecksing

2 InterPro domains/families:

IPR009071 HMG_superfamily

IPR024970 Maelstrom

Graphical View of Domain Structure for InterPro Entry Q96JY0

ProtoNet protein and cluster: Q96JY0

UniProtKB/Swiss-Prot: MAEL_HUMAN, Q96JY0

Similarity: Belongs to the maelstrom family

Similarity: Contains 1 HMG box DNA-binding domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: MAEL_HUMAN, Q96JY0

Function: Plays a central role during spermatogenesis by repressing transposable elements and prevent their

mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the

repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and

govern the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a

participation in the secondary piRNAs metabolic process. Required for localization of germ-cell factors to the meiotic

nuage (By similarity)

miRNA Products:		OriGene 3'-UTR Clone: MAEL Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MAEL
		1 QIAGEN miScript miRNA Assays for microRNA that regulate MAEL:
		hsa-miR-624*
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Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MAEL (see all 7) OriGene shRNA RFP: MAEL OriGene siRNA: MAEL
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Gene Editing
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		Search LifeMap BioReagents cell lines for MAEL

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAEL

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003677	DNA binding	IEA	--
GO:0005515	protein binding	--	--

MAEL for ontologies About GeneDecksing

Animal Models:
3 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Mael):

cellular

endocrine/exocrine gland

reproductive system

MAEL for phenotypes About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for MAEL

STRING Interaction Network Preview (showing 5 interactants - click image to see 8)

5/8 Interacting proteins for MAEL (Q96JY0³ ENSP00000356846⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 8)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
SIN3B	O75182³, ENSP00000369131⁴	I2D: score=1 STRING: ENSP00000369131
SMARCB1	Q12824³, ENSP00000263121⁴	I2D: score=1 STRING: ENSP00000263121
TDRD1	Q9BXT4³, ENSP00000251864⁴	I2D: score=1 STRING: ENSP00000251864
PIWIL2	Q8TC59³, ENSP00000349208⁴	I2D: score=1 STRING: ENSP00000349208
PIWIL1	Q96J94³, ENSP00000245255⁴	I2D: score=1 STRING: ENSP00000245255

About this table

Gene Ontology (GO): 5/16 biological process terms (GO ID links to tree view) (see all 16): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	IEA	--
GO:0000902	cell morphogenesis	IEA	--
GO:0006974	response to DNA damage stimulus	IEA	--
GO:0007128	meiotic prophase I	IEA	--
GO:0007129	synapsis	IEA	--

MAEL for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for MAEL
Search CenterWatch for drugs/clinical trials and news about MAEL

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
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Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for MAEL gene:

NM_032858.1

Unigene Cluster for MAEL:

Maelstrom spermatogenic transposon silencer

Hs.651245 [show with all ESTs]

Unigene Representative Sequence: BC034310

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000367872(uc021peh.1 uc001gdy.1 uc001gdz.1) ENST00000447624

ENST00000491055(uc009wvf.1) ENST00000487826 ENST00000367870

miRNA Products:		OriGene 3'-UTR Clone: MAEL Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MAEL
		1 QIAGEN miScript miRNA Assays for microRNA that regulate MAEL:
		hsa-miR-624*
		SwitchGear 3'UTR luciferase reporter plasmid: MAEL 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MAEL (see all 7) OriGene shRNA RFP: MAEL OriGene siRNA: MAEL
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MAEL

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		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAEL
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAEL

Additional cDNA sequence:

AK027810.1 AK131066.1 AK302253.1 AL133073.1 BC028595.2 BC034310.1 DQ076156.2 GU383113.1

GU383114.1

7 DOTS entries:

DT.413784 DT.91818096 DT.97837568 DT.100790988 DT.99946801 DT.100020079 DT.121440223

24/147 AceView cDNA sequences (see all 147):

AA416959 BP371250 CR624981 BI825432 BP369554 AA470046 CR597287 AW134538

BP371654 AA393260 AA398518 BP370827 BI829160 AA608981 AI138893 AA421199

CR614428 BP371720 CA488170 AL133073 BP369150 AI769054 AA412123 BP369432

GeneLoc Exon Structure

5/9 Alternative Splicing Database (ASD) splice patterns (SP) for MAEL (see all 9) About this scheme

ExUns:	1a	·	1b	·	1c	^	2	^	3a	·	3b	^	4	^	5a	·	5b	·	5c	·	5d	^	6	^	7a	·	7b	^	8	^	9a	·	9b	·	9c	^	10	^	11	^	12	^	13a	·	13b	^	14a	·	14b
SP1:																																			-
SP2:																																			-		-
SP3:																																			-		-
SP4:																																			-		-
SP5:																																			-		-

ECgene alternative splicing isoforms for MAEL

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

MAEL expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AAGAAAATGA

About this image

MAEL expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Intermediate limb mesenchymal cells (ILM cells) (Primary Cell)

Bone, Cartilage, Limb

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See MAEL Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MAEL

SOURCE GeneReport for Unigene cluster: Hs.651245

UniProtKB/Swiss-Prot: MAEL_HUMAN, Q96JY0

Tissue specificity: Testis-specific. Expressed in various cancer cell lines, probably due to demethylation of its

promoter

SABiosciences Custom PCR Arrays for MAEL

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAEL

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for MAEL gene from 4/12 species (see all 12) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Mael^{1 , 5}	maelstrom homolog (Drosophila)^{1, 5}	89.63(n)¹ 89.86(a)¹		1 (73.56 cM)⁵ 98558¹ NM_175296.4¹ NP_780505.1¹ 166201385⁵
chicken (Gallus gallus)	Aves	MAEL¹	maelstrom homolog (Drosophila)	61.76(n) 52.87(a)		418446 XM_416657.3 XP_416657.2
lizard (Anolis carolinensis)	Reptilia	MAEL⁶	--	53(a)	1 ↔ 1	1(186884952-186885767)
fruit fly (Drosophila melanogaster)	Insecta	mael⁶	maelstrom	16(a)	1 ↔ 1	3L(22717333-22719334)

ENSEMBL Gene Tree for MAEL (if available)
TreeFam Gene Tree for MAEL (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs6427049^1,2	C,F,A,H,	--	166956593(+)	`AATAGC/TTCATT`	1	--	us2k¹		8		NA WA CSA EA	368
rs6669886^1,2	C,F,H,	--	166956710(+)	`GCTACT/CCTCAA`	1	--	us2k¹		10		NS EA NA CSA WA	738
rs6656999^1,2	C,F,A,	--	166956807(+)	`GTCAAC/GCAGTT`	1	--	us2k¹		9		NA WA CSA EA	370
rs144150326^1,2		--	166956851(+)	`TTCAGA/TTCCTT`	1	--	us2k¹		0	--	--	--	--
rs184046663^1,2		--	166956931(+)	`ACAAAA/CATTAG`	1	--	us2k¹		0	--	--	--	--
rs138779981^1,2		--	166957141(+)	`AAATAC/TCACAA`	1	--	us2k¹		0	--	--	--	--
rs10918606^1,2	C,F,A,H,	--	166957249(+)	`TACTAA/GGAATG`	1	--	us2k¹		11		NA WA CSA EA	484
rs12121480^1,2	H	--	166957258(+)	`tggtaG/Cgctgc`	1	--	us2k¹		4		NS EA	416
rs141829313^1,2		--	166957267(+)	`GCATCA/GTTAGA`	1	--	us2k¹		0	--	--	--	--
rs11578707^1,2	C,H	--	166957305(+)	`aattaG/Agccag`	1	--	us2k¹		5		NS EA NA	404

HapMap Linkage Disequilibrium report for MAEL (166958346 - 166991451 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 1 variation for MAEL
1 CNV: 8338

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MAEL

DNA2.0 Custom Variant and Variant Library Synthesis for MAEL

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

MAEL for disorders           About GeneDecksing

OMIM gene information: 611368    OMIM disorders: --

5 diseases for MAEL:    About MalaCards

gonorrhea essential hypertension hypertension t-cell leukemia

leukemia

Human Genome Epidemiology (HuGE) Navigator: MAEL (3 documents)

Export disorders for MAEL gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for MAEL gene, integrated from 9 sources (see all 13):
(articles sorted by number of sources associating them with MAEL)

Utopia: connect your pdf to the dynamic
world of online information

Identification of a novel human cancer/testis gene MAEL that is regulated by DNA methylation. (PubMed id 19693694)^{1, 2, 3} Xiao L....Zhang J. (2009)
Mouse maelstrom, a component of nuage, is essential fo r spermatogenesis and transposon repression in meiosis. (PubMed id 18694567)^{1, 3} Soper S.F....Bortvin A. (2008)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{1, 2} Gregory S.G.... Bentley D.R. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)^{1, 3} Strausberg R.L....Marra M.A. (2002)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
Follow-up of a major linkage peak on chromosome 1 rev eals suggestive QTLs associated with essential hypertension: GenNet study. (PubMed id 19536175)¹ Ehret G.B....Chakravarti A. (2009)
Pre-B-cell leukemia homeobox 1 (PBX1) shows functional and possible genetic association with bone mineral density variation. (PubMed id 19064610)¹ Cheung C.L....Kung A.W. (2009)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)¹ Barbe L....Andersson-Svahn H. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 84944	HGNC: 25929	AceView: FLJ14904	Ensembl:ENSG00000143194	euGenes: HUgn84944
ECgene: MAEL	H-InvDB: MAEL

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for MAEL	Pharmacogenomics, SNPs, Pathways

Intellectual Property for MAEL gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for MAEL gene:
Search GeneIP for patents involving MAEL

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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for MAEL gene

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for MAEL gene

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for MAEL gene

Disorders / Diseases
for MAEL gene

Publications
for MAEL gene

Intellectual Property
for MAEL gene

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