Aliases for MAEL Gene
External Ids for MAEL Gene
Previous GeneCards Identifiers for MAEL Gene
GeneCards Summary for MAEL Gene
MAEL (Maelstrom Spermatogenic Transposon Silencer) is a Protein Coding gene.
UniProtKB/Swiss-Prot for MAEL Gene
Plays a central role during spermatogenesis by repressing transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Its association with piP-bodies suggests a participation in the secondary piRNAs metabolic process. Required for the localization of germ-cell factors to the meiotic nuage (By similarity).