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MADCAM1 Gene

protein-coding GIFtS: 53

GC19P000450

mucosal vascular addressin cell adhesion molecule 1
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
MACAM1 ^¹, ²
MAdCAM-1 ^³
hMAdCAM-1 ^³

Descriptions
mucosal addressin cell adhesion molecule-1 ^²
mucosal vascular addressin cell adhesion molecule 1 ^²

External Ids
HGNC: 6765¹
Entrez Gene: 8174²
UniProtKB: Q13477³
Ensembl: ENSG00000099866⁷

Search outside databases for aliases for MADCAM1 gene

Previous GC identifers: GC19P000507 GC19P000531 GC19P000436 GC19P000448 GC19P000449

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for MADCAM1:

The protein encoded by this gene is an endothelial cell adhesion molecule that interacts

preferentially with the leukocyte beta7 integrin LPAM-1 (alpha4beta7), L-selectin, and VLA-4

(alpha4beta1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues. It is a

member of the immunoglobulin family and is similar to ICAM1 and VCAM1. At least seven

alternatively spliced transcripts encoding different protein isoforms have been found for this

gene, but the full-length nature of some variants has not been determined. [provided by RefSeq]

UniProtKB/Swiss-Prot: MADCA_HUMAN, Q13477

Function: Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte

traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can

bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of

leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin

alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the MADCAM1 gene

Entrez Gene cytogenetic band: 19p13.3 Ensembl cytogenetic band: 19p13.3 HGNC cytogenetic band: 19p13.3

MADCAM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19P000450: (about GC identifiers)

Start:	447,490 bp from pter
End:	456,343 bp from pter
Size:	8,854 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000019.8 NT_011255.14

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: MADCA_HUMAN, Q13477 (See protein sequence)

Recommended Name: Mucosal addressin cell adhesion molecule 1 precursor

Size: 382 amino acids; 40155 Da

Subunit: Homodimer (Probable)

Subcellular location: Membrane; Single-pass type I membrane protein

PDB structure from and Proteopedia :

1BQS (3D)

1GSM (3D)

Secondary accessions: A5PKV4 O60222 O75867

Alternative splicing: 2 isoforms: Q13477-1 Q13477-2 (Additional isoforms seem to exist)

Post-translational modifications:

The Ser/Thr-rich mucin-like domain may provide possible sites for O-glycosylation (By similarity)¹

REFSEQ proteins (2 alternative transcripts):

NP_570116.2 NP_570118.1

ENSEMBL proteins:

ENSP00000346203 ENSP00000372131 ENSP00000215637 ENSP00000304247 ENSP00000372130

Human Recombinant Proteins

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	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (MAdCAM1)
	Browse Abnova for Human Recombinant Proteins

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

3 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005624	membrane fraction	TAS	8502297
GO:0005886	plasma membrane	EXP	12588680
GO:0016021	integral to membrane	IEA	--

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Antibodies for MADCAM1:

	Invitrogen Antibodies for MADCAM1
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse Antibodies at Sigma-Aldrich
	R&D Systems Antibodies for MADCAM1 (MAdCAM-1)
	Antibodies from Abcam (MAdCAM1), each with their Abpromise^SM
	Browse Abnova for Monoclonal and Polyclonal Antibodies
	Search Novus for antibodies for MADCAM1

Assays for MADCAM1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q13477

ProtoNet protein and cluster: Q13477

1 Blocks protein family: IPB003599 Immunoglobulin subtype

UniProtKB/Swiss-Prot: MADCA_HUMAN, Q13477

Similarity: Contains 2 Ig-like (immunoglobulin-like) domains

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MADCAM1)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_130760

Applied Biosystems Silencer® siRNAs for MADCAM1

Sigma-Aldrich siRNA for MADCAM1

Sigma-Aldrich shRNA Panels and shRNA for MADCAM1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_130760
Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_130760
untagged cDNA clones in CMV expression vector (see all 3): NM_130760

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_130760

UniProtKB/Swiss-Prot: MADCA_HUMAN, Q13477

Function: Cell adhesion leukocyte receptor expressed by mucosal venules, helps to direct lymphocyte

traffic into mucosal tissues including the Peyer patches and the intestinal lamina propria. It can

bind both integrin alpha-4/beta-7 and L-selectin, regulating both the passage and retention of

leukocytes. Isoform 2, lacking the mucin-like domain, may be specialized in supporting integrin

alpha-4/beta-7-dependent adhesion strengthening, independent of L-selectin binding

Genatlas biochemistry entry for MADCAM1:

mucosal vascular addressin cell adhesion molecule 1,ligand for leukocyte B7 integrin (LPAM-1) L

selectin,VLA-4 on myeloid cells,with two alternatively spliced forms,homing leukocytes to mucosal

inflammed tissues

1 Gene Ontology (GO) molecular function term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005515	protein binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for MADCAM1

5/29 Interacting proteins for MADCAM1 (ENSP00000346203³) via UniProtKB, MINT, and/or STRING (see all 29 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
ITGA4	ENSP00000233573³	STRING (score=.999)
ITGB7	ENSP00000267082³	STRING (score=.99)
NKX2-3	ENSP00000342828³	STRING (score=.987)
SELL	ENSP00000236147³	STRING (score=.973)
LTBR	ENSP00000228918³	STRING (score=.965)

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006955	immune response	TAS	8502297
GO:0007155	cell adhesion	TAS	8502297
GO:0007165	signal transduction	TAS	8502297

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for MADCAM1
5 Novoseek chemical compound relationships for MADCAM1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
tripeptide	36.29	2	9873398 (1), 11573247 (1)
rantes	28.26	1	12537753 (1)
manganese	2.70	3	7512373 (2), 12699089 (1)
sulfate	0.02	1	9466573 (1)
nitric oxide	0.00	1	11481030 (1)

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(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (MADCAM1)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 3): NM_130760

Sigma-Aldrich siRNA for MADCAM1

Sigma-Aldrich shRNA Panels and shRNA for MADCAM1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_130760 NM_130762

REFSEQ mRNAs for MADCAM1 gene (2 alternative transcripts):

NM_130760.2 NM_130762.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_130760 NM_130762

               OriGene GFP tagged cDNA clones in CMV expression vector (see all 2): NM_130760
                                 Myc/DDK tagged cDNA clones in CMV expression vector (see all 2): NM_130760
                                 untagged cDNA clones in CMV expression vector (see all 3): NM_130760

Additional cDNA sequence:

AK092211.1 AY732484.1 AY819760.1 BC136408.1 BC137506.1 BC137507.1 BC142629.1 BC144065.1

DQ076657.1 U43628.1 U82483.1

4 DOTS entries:

DT.409211 DT.92360074 DT.99932820 DT.99965995

18 AceView cDNA sequences:

NM_130762 AI131233 BI821776 AW340299 AA678836 AA928768 BM702750 NM_130760

U82483 AA668527 U43628 AA705935 NM_130761 AK092211 AW340202 T54621

T54705 BE173884

highest scoring ESTs for MADCAM1:

AA668527 AA705935 AK092211 AW340202 BM702750 U43628 U82483 AA928768 AI131233 AW340299

Unigene Cluster for MADCAM1:

Mucosal vascular addressin cell adhesion molecule 1

Hs.102598 [show with all ESTs]

Unigene Representative Sequence: AK092211

GeneLoc Exon Structure

5 Ensembl transcripts including schematic representations:

ENST00000354255 ENST00000382684 ENST00000215637 ENST00000346144 ENST00000382683

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
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MADCAM1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for MADCAM1

¹ / ² / ³

3 probe-sets matching MADCAM1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
34429_at²^{, 3}	U95-A	1	1.00	1.00	1.00	1.00	AC005775	0.20	1.00	0.72	1
208037_s_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_007164	0.20	1.00	0.72	1
208037_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: TCTCACGTCT

SOURCE GeneReport for Unigene cluster: Hs.102598
Expression variation in blood from EXPOLDB for MADCAM1
UniProtKB/Swiss-Prot: MADCA_HUMAN, Q13477
Tissue specificity: Highly expressed on high endothelial venules (HEV) and lamina propia venules
found in the small intestine, and to a lesser extent in the colon and spleen. Very low levels of
expression found in pancreas and brain. Not expressed in the thymus, prostate, ovaries, testis,
heart, placenta, lung, liver, skeletal muscle, kidneys or peripheral blood leukocytes

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for MADCAM1 gene from 3 species

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	MADCAM1¹	--	mucosal vascular addressin cell adhesion molecule 1	69.54(n) 61.42(a)	485103 NM_001024639.1 NP_001019810.1
rat (Rattus norvegicus)	Madcam1¹	--	mucosal vascular addressin cell adhesion molecule 1	62.9(n) 56.27(a)	54266 NM_019317.1 NP_062190.1
mouse (Mus musculus)	Madcam1^{1, 5}	10 (43.00 cM)⁵	mucosal vascular addressin cell adhesion molecule 1^{1, 5}	63.09(n)¹ 53.04(a)¹	17123¹ NM_013591.1¹ NP_038619.1¹ AK137028⁵ AK156096⁵ (see all 15)

About this table Species with no ortholog for MADCAM1

ENSEMBL Gene Tree for MADCAM1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

UniProtKB/Swiss-Prot: MADCA_HUMAN, Q13477

Polymorphism: The number of repeats in the mucin domain varies between 5 and 8 repeats

10/70 NCBI SNPs in MADCAM1 are shown (see all 70 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 34)

AB	SNP ID	Valid	Chr 19 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs758503^1,2	A,C,F,H	446722(+)	`CAGGGG/TGCCTC`	2	--	ng5¹		6		EU EA WA NA	598
	rs758502^1,2	A,C,F	446600(+)	`CAGGCT/CTGCTA`	2	--	ng5¹		3		MN NA	366
--	rs1140823^1,2	A,C,F	456071(+)	`ctctgT/Ctcaca`	2	--	ut3¹ ese³		1		MN	184
	rs3745925^1,2	C,F,H	452900(-)	`GCGTGG/TGCCCA`	2	P/H	mis¹ int¹ ese³		5		EA EU WA	1880
--	rs9653134^1,2	A	445574(+)	`CACCCC/TGGGCC`	2	--	ng5¹		0	--	--	--	--
	rs7246543^1,2	A,C,F,H	455830(+)	`CCCACC/GTATCA`	2	T/T	syn¹		5		EU EA WA NA	484
	rs2302217^1,2	A,C,F	449524(+)	`TCCCCG/AGCAGC`	2	P/P	syn¹ ese³		6		EA NA	1820
	rs12982646^1,2	C,F,H	450978(+)	`ACCCGG/AGAGGT`	2	--	int¹		4		EU EA WA	420
	rs6510810^1,2	A,C,F	451359(+)	`CTCAGC/TTTCCT`	2	--	int¹		2		EA	180
--	rs2392801^1,2	A,C	454917(+)	`gtggcA/Gtgtgc`	2	--	int¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for MADCAM1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 102670

10/16 Novoseek disease relationships for MADCAM1 gene (see all 16 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
inflammatory bowel diseases	67.20	20	11472325 (5), 10562584 (2), 11343233 (2), 11481030 (1) (see all 8)
colitis	49.07	4	16917232 (2), 12625840 (1)
ileitis	46.65	3	16401463 (2), 15699171 (1)
inflammation	43.59	20	10661685 (2), 9036954 (2), 16401463 (2), 10562584 (1) (see all 12)
malt lymphoma	42.31	2	11504840 (1), 14669317 (1)
lymphoma t-cell	40.49	1	10508262 (1)
lymphoma low-grade	40.30	1	11504840 (1)
cholangitis primary sclerosing	35.46	5	11343233 (3), 16750586 (2)
colitis ulcerative	32.07	3	9212736 (1), 19067429 (1), 9214052 (1)
lymphoma	31.49	2	7517418 (1), 7687523 (1)

About this table

Human Genome Epidemiology Navigator: MADCAM1 (2 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/134 PubMed articles for MADCAM1 gene (see all 134 ):

Human mucosal addressin cell adhesion molecule-1 (MAdCAM-1) demonstrates structural and functional similarities to the alpha 4 beta 7-integrin binding domains of murine MAdCAM-1, but extreme divergence of mucin-like sequences. (PubMed id 8609404)^{1, 2, 3, 4} Shyjan A.M....Briskin M.J. (1996)
Genomic organization, chromosomal mapping, and analysis of the 5' promoter region of the human MAdCAM-1 gene. (PubMed id 9162097)^{1, 2, 3, 4} Leung E.... Krissansen G.W. (1997)
The structure of immunoglobulin superfamily domains 1 and 2 of MAdCAM-1 reveals novel features important for integrin recognition. (PubMed id 9655832)^{1, 3, 4} Tan K....Wang J.H. (1998)
A reassessment of the MAdCAM-1 structure and its role in integrin recognition. (PubMed id 11807247)^{1, 3, 4} Dando J.... Brady R.L. (2002)
Cloning of the mucosal addressin MAdCAM-1 from human brain: identification of novel alternatively spliced transcripts. (PubMed id 8989586)^{1, 3, 4} Leung E....Krissansen G.W. (1996)
The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)^{3, 4} Grimwood J.... Lucas S.M. (2004)
Mechanisms of MAdCAM-1 gene expression in human intestinal microvascular endothelial cells. (PubMed id 15483224)^{1, 3} Ogawa H....Rafiee P. (2005)
Structure-function analysis of the integrin beta 7 subunit: identification of domains involved in adhesion to MAdCAM-1. (PubMed id 9233649)^{1, 3} Tidswell M....Erle D.J. (1997)
Human mucosal addressin cell adhesion molecule-1 is preferentially expressed in intestinal tract and associated lymphoid tissue. (PubMed id 9212736)^{1, 3} Briskin M....Ringler D.J. (1997)
CCL25 and CCL28 promote alpha4 beta7-integrin-dependent adhesion of lymphocytes to MAdCAM-1 under shear flow. (PubMed id 18308860)^{1, 3} Miles A....Adams D.H. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 8174	HGNC: 6765	AceView: MADCAM1	Ensembl:ENSG00000099866	euGenes: HUgn8174
ECgene: MADCAM1	H-InvDB: MADCAM1

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for MADCAM1
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for MADCAM1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for MADCAM1-related products

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	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
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MADCAM1 Gene

protein-coding GIFtS: 53

Aliases &
Descriptions
for MADCAM1

Summaries
for MADCAM1

Genomic Location
for MADCAM1

Proteins
for MADCAM1

Protein Domains/
Families
for MADCAM1

Gene Function
for MADCAM1

Pathways & Interactions
for MADCAM1

Drugs & Compounds
for MADCAM1

Transcripts
for MADCAM1

Expression
for MADCAM1

Orthologs
for MADCAM1

Paralogs
for MADCAM1

SNPs/Variants
for MADCAM1

Disorders & Mutations
for MADCAM1

Medical News
for MADCAM1

Publications
for MADCAM1

Search for MADCAM1

Genome Databases showing MADCAM1

Other Databases showing MADCAM1

Specialized Databases showing MADCAM1

Licensable Technologies
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Services
for MADCAM1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

MADCAM1 Gene

protein-coding GIFtS: 53

Aliases & Descriptionsfor MADCAM1

Summariesfor MADCAM1

Genomic Locationfor MADCAM1

Proteinsfor MADCAM1

Protein Domains/Familiesfor MADCAM1

Gene Functionfor MADCAM1

Pathways & Interactionsfor MADCAM1

Drugs & Compoundsfor MADCAM1

Transcriptsfor MADCAM1

Expression for MADCAM1

Orthologsfor MADCAM1

Paralogsfor MADCAM1

SNPs/Variantsfor MADCAM1

Disorders & Mutationsfor MADCAM1

Medical Newsfor MADCAM1

Publicationsfor MADCAM1

Search for MADCAM1

Genome Databases showing MADCAM1

Other Databases showing MADCAM1

Specialized Databases showing MADCAM1

Licensable Technologiesfor MADCAM1

Servicesfor MADCAM1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for MADCAM1

Summaries
for MADCAM1

Genomic Location
for MADCAM1

Proteins
for MADCAM1

Protein Domains/
Families
for MADCAM1

Gene Function
for MADCAM1

Pathways & Interactions
for MADCAM1

Drugs & Compounds
for MADCAM1

Transcripts
for MADCAM1

Expression
for MADCAM1

Orthologs
for MADCAM1

Paralogs
for MADCAM1

SNPs/Variants
for MADCAM1

Disorders & Mutations
for MADCAM1

Medical News
for MADCAM1

Publications
for MADCAM1

Licensable Technologies
for MADCAM1

Services
for MADCAM1