Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MAD2L1BP Gene

protein-coding   GIFtS: 50
GCID: GC06P043597

MAD2L1 binding protein
 Explore 2 diseases affiliated with
MAD2L1BP via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for MAD2L1BP    

Aliases
for MAD2L1BP gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
MAD2L1 Binding Protein1 2     DJ261G23.11
CMT21 2 3     RP1-261G23.62
KIAA01101 3     MAD2L1-Binding Protein2
Caught By MAD2 Protein2 3     

External Ids:    HGNC: 210591   Entrez Gene: 95872   Ensembl: ENSG000001246887   UniProtKB: Q150133   

Export aliases for MAD2L1BP gene to outside databases

Previous GC identifers: GC06P043598 GC06P043650 GC06P043711 GC06P043316


Summaries
for MAD2L1BP gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for MAD2L1BP:
The protein encoded by this gene was identified as a binding protein of the MAD2 mitotic arrest deficient-like 1
(MAD2/MAD2L1). MAD2 is a key component of the spindle checkpoint that delays the onset of anaphase until all the
kinetochores are attached to the spindle. This protein may interact with the spindle checkpoint and coordinate cell
cycle events in late mitosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
(provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: MD2BP_HUMAN, Q15013
Function: May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding
MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex

Gene Wiki entry for MAD2L1BP


Genomic Views
for MAD2L1BP gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_007592.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MAD2L1BP gene promoter:
         NRSF form 1   NRSF form 2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): MAD2L1BP promoter sequence
   Search SABiosciences Chromatin IP Primers for MAD2L1BP

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAD2L1BP


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.1   Ensembl cytogenetic band:  6p21.1   HGNC cytogenetic band: 6p21.1

MAD2L1BP Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MAD2L1BP gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P043597:  view genomic region     (about GC identifiers)

Start:
 43,597,277 bp from pter      End:
 43,608,689 bp from pter
Size:
 11,413 bases      Orientation:
 plus strand

Proteins
for MAD2L1BP gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: MD2BP_HUMAN, Q15013 (See protein sequence)
Recommended Name: MAD2L1-binding protein  
Size: 274 amino acids; 31052 Da
Subunit: Interacts with MAD2L1
Subcellular location: Nucleus. Cytoplasm, cytoskeleton, spindle. Note=During early mitosis, unevenly distributed
throughout the nucleoplasm. From metaphase to anaphase, concentrated on the spindle
Developmental stage: During the cell cycle, levels increase and then remain constant until late mitosis after which
they drop
Sequence caution: Sequence=BAG59665.1; Type=Erroneous initiation;
1 PDB 3D structure from and Proteopedia for MAD2L1BP:
2QYF (3D)    
Secondary accessions: B4DLV3 E9PAT7 Q6IBB1
Alternative splicing: 2 isoforms:  Q15013-1   Q15013-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for MAD2L1BP: NX_Q15013

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q15013

    • MAD2L1BP Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_001003690.1  NP_055443.1  

    ENSEMBL proteins: 
     ENSP00000410818   ENSP00000361244  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: MAD2L1BP
    OriGene Protein Over-expression Lysate (see all 2): MAD2L1BP
    OriGene Custom Protein Services for MAD2L1BP 
    GenScript Custom Purified and Recombinant Proteins Services for MAD2L1BP
    Novus Biologicals MAD2L1BP Proteins
    Novus Biologicals MAD2L1BP Lysates
    Browse Sino Biological Recombinant Proteins
    ProSpec Recombinant Protein for MAD2L1BP
    Uscn Proteins for MAD2L1BP

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA10942595
    GO:0005737cytoplasm IDA10942595
    GO:0005819spindle IEA--


    MAD2L1BP for ontologies           About GeneDecksing



    MAD2L1BP Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for MAD2L1BP 
    GenScript Custom Superior Antibodies Services for MAD2L1BP
    Novus Biologicals MAD2L1BP Antibodies
    Abcam antibodies for MAD2L1BP 
    Uscn Antibodies for MAD2L1BP
    ThermoFisher Antibodies for MAD2L1BP

    Assay Products for MAD2L1BP: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for MAD2L1BP
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for MAD2L1BP

    Protein Domains /
    Families
    for MAD2L1BP gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    MAD2L1BP for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR009511 MAD1/Cdc20-bound-Mad2-bd

    Graphical View of Domain Structure for InterPro Entry Q15013

    ProtoNet protein and cluster: Q15013

    UniProtKB/Swiss-Prot: MD2BP_HUMAN, Q15013
    Similarity: Belongs to the MAD2L1BP family


    Function
    for MAD2L1BP gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: MD2BP_HUMAN, Q15013
    Function: May function to silence the spindle checkpoint and allow mitosis to proceed through anaphase by binding
    MAD2L1 after it has become dissociated from the MAD2L1-CDC20 complex

    miRNA
    Products:            		 OriGene 3'-UTR Clone (see all 2): MAD2L1BP
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MAD2L1BP
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate MAD2L1BP:
    hsa-miR-4314 hsa-miR-3157-5p
    SwitchGear 3'UTR luciferase reporter plasmid: MAD2L1BP 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MAD2L1BP (see all 7)
    OriGene shRNA RFP: MAD2L1BP
    OriGene siRNA: MAD2L1BP
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MAD2L1BP

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for MAD2L1BP

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAD2L1BP (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAD2L1BP (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): MAD2L1BP (NM_001003690)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MAD2L1BP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAD2L1BP 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for MAD2L1BP
    Search LifeMap BioReagents cell lines for MAD2L1BP

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAD2L1BP

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI19060904


    MAD2L1BP for ontologies           About GeneDecksing



    Pathways & Interactions
    for MAD2L1BP gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MAD2L1BP

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/19 Interacting proteins for MAD2L1BP (Q150131, 2, 3 ENSP000004108184) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    KRT15P190122, 3, ENSP000002540434MINT-68374 I2D: score=5 STRING: ENSP00000254043
    SGOL2Q562F62, 3MINT-8211808 MINT-8211761 I2D: score=1 
    KAT5Q929932, 3MINT-64193 I2D: score=5 
    KIAA1377Q9P2H02, 3MINT-64195 I2D: score=5 
    PTNP212462, 3MINT-64189 I2D: score=5 
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007093mitotic cell cycle checkpoint IMP18022368
    GO:0007096regulation of exit from mitosis IMP12456649


    MAD2L1BP for ontologies           About GeneDecksing



    Drugs & Compounds
    for MAD2L1BP gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MAD2L1BP
    Search CenterWatch for drugs/clinical trials and news about MAD2L1BP / MD2BP 

    Transcripts
    for MAD2L1BP gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for MAD2L1BP gene (2 alternative transcripts): 
    NM_001003690.1  NM_014628.2  

    Unigene Clusters for MAD2L1BP:

    MAD2L1 binding protein
    Hs.122346  [show with all ESTs], Hs.715485
    Unigene Representative Sequences: NM_001003690, AK297172
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000451025(uc003ovu.3) ENST00000372171(uc003ovv.3) ENST00000508232


    miRNA
    Products:             		 OriGene 3'-UTR Clone (see all 2): MAD2L1BP
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MAD2L1BP
    2 QIAGEN miScript miRNA Assays for microRNAs that regulate MAD2L1BP:
    hsa-miR-4314 hsa-miR-3157-5p
    SwitchGear 3'UTR luciferase reporter plasmid: MAD2L1BP 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MAD2L1BP (see all 7)
    OriGene shRNA RFP: MAD2L1BP
    OriGene siRNA: MAD2L1BP
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MAD2L1BP
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAD2L1BP (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAD2L1BP (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector (see all 2): MAD2L1BP (NM_001003690)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MAD2L1BP
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAD2L1BP 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MAD2L1BP
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MAD2L1BP
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAD2L1BP
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAD2L1BP

    Additional cDNA sequence: AK297172.1 

    9 DOTS entries:

    DT.101957052  DT.100787342  DT.317149  DT.100787337  DT.100787341  DT.100787338  DT.121405644  DT.121405365 
    DT.95373520 

    24/229 AceView cDNA sequences (see all 229):

    BM809395 CR605087 BQ945849 BF941669 BM559214 BQ183719 BE264993 BQ688762 
    BC002904 AI311810 AI017834 BM793738 BF314371 BU173954 BG388904 BX282156 
    AA749168 CR601298 BE732337 BM726186 BE254750 CA397952 BM682613 BM915708 

    GeneLoc Exon Structure


    Expression
    for MAD2L1BP gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MAD2L1BP expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TGGCTGTGAC

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    MAD2L1BP expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    ES04(HES-4) (Embryonic Stem Cell)Early Embryo, Inner Cell Mass
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See MAD2L1BP Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MAD2L1BP

    SOURCE GeneReport for Unigene clusters: Hs.122346 Hs.715485
        SABiosciences Custom PCR Arrays for MAD2L1BP
    Primer
    Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MAD2L1BP
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MAD2L1BP
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAD2L1BP
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAD2L1BP
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAD2L1BP

    Orthologs
    for MAD2L1BP gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for MAD2L1BP gene from 4/12 species (see all 12)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Mad2l1bp1 , 5 MAD2L1 binding protein1, 5 81.37(n)1
    79.85(a)1    		   17 (22.88 cM)5
    665911  NM_025649.31  NP_079925.21 
     461473905 
    chicken
    (Gallus gallus)    		 Aves MAD2L1BP1 MAD2L1 binding protein 65.43(n)
    63.43(a)    		   421448  XM_419498.3  XP_419498.1 
    lizard
    (Anolis carolinensis)    		 Reptilia MAD2L1BP6
    		 --
    		 56(a)
    		 1 ↔ 1
    		 1(230920800-230926257)
    zebrafish
    (Danio rerio)    		 Actinopterygii CABZ01113413.16
    		 --
    		 26(a)
    		 1 ↔ 1
    		 13(33919983-33925003)


    ENSEMBL Gene Tree for MAD2L1BP (if available)
    TreeFam Gene Tree for MAD2L1BP (if available) 

    Paralogs
    for MAD2L1BP gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    		  --

    Genomic Variants
    for MAD2L1BP gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/253 NCBI SNPs in MAD2L1BP are shown (see all 253)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs22322131,2
    		F,--43595289(-) TGTCCG/ACTTCA 2 -- us2k1 int13Minor allele frequency- A:0.06WA NA EA 358
    rs22322121,2
    		--43595500(-) GAAAAC/ATAAAA 2 -- int1 us2k12Minor allele frequency- A:0.20CSA WA 120
    rs22322111,2
    		F,--43595585(-) CATGAA/GGTGGA 2 -- us2k1 int13Minor allele frequency- G:0.14CSA WA 122
    rs22322101,2
    		--43595589(-) ACACCA/GTGAAG 2 -- int1 us2k10--------
    rs2011685221,2
    		--43595599(+) TGTTA-/AGGAGATT 2 -- int1 us2k10--------
    rs1397859111,2
    		C,--43595637(+) CTTTT-/AATC  
                ATTTT     		2 -- us2k1 int10--------
    rs1442928361,2
    		--43595829(+) GGCACA/GGAGGC 2 -- us2k1 int10--------
    rs117531051,2
    		C,H--43595930(+) accccA/Gtctct 2 -- us2k1 int10--------
    rs1821829111,2
    		C,--43595937(+) CTCTAA/CTAAAA 2 -- us2k1 int10--------
    rs117531061,2
    		H--43595939(+) ctactA/Gaaaat 2 -- int1 us2k10--------

    HapMap Linkage Disequilibrium report for MAD2L1BP (43597277 - 43608689 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for MAD2L1BP: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MAD2L1BP
    DNA2.0 Custom Variant and Variant Library Synthesis for MAD2L1BP

    Disorders / Diseases
    for MAD2L1BP gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    MAD2L1BP for disorders           About GeneDecksing

    2 diseases for MAD2L1BP:    About MalaCards
    hepatocellular carcinoma    carcinoma


    Export disorders for MAD2L1BP gene to outside databases

    Publications
    for MAD2L1BP gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MAD2L1BP gene, integrated from 9 sources (see all 30):
    (articles sorted by number of sources associating them with MAD2L1BP)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of a MAD2-binding protein, CMT2, and its role in mitosis. (PubMed id 12456649)1, 2, 3, 9 Habu T.... Matsumoto T. (2002)
    2. Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 7788527)1, 2, 3 Nagase T....Kotani H. (1995)
    3. p31comet blocks Mad2 activation through structural mimicry. (PubMed id 18022368)1, 2 Yang M.... Luo X. (2007)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    6. Role of phosphorylation of Cdc20 in p31(comet)-stimula ted disassembly of the mitotic checkpoint complex. (PubMed id 22566641)1 Miniowitz-Shemtov S....Hershko A. (2012)
    7. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    8. Depletion of p31comet protein promotes sensitivity to antimitotic drugs. (PubMed id 22544748)1 Ma H.T....Poon R.Y. (2012)
    9. p31comet-mediated extraction of Mad2 from the MCC prom otes efficient mitotic exit. (PubMed id 22100920)1 Westhorpe F.G....Taylor S.S. (2011)
    10. p31comet Promotes disassembly of the mitotic checkpoi nt complex in an ATP-dependent process. (PubMed id 21300909)1 Teichner A....Hershko A. (2011)

    External Searches for MAD2L1BP gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing MAD2L1BP gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9587 HGNC: 21059 AceView: MAD2L1BP Ensembl:ENSG00000124688 euGenes: HUgn9587
    ECgene: MAD2L1BP H-InvDB: MAD2L1BP

    Other Databases showing MAD2L1BP gene

    (According to HUGE)
    About This Section
    HUGE: KIAA0110

    Specialized Databases showing MAD2L1BP gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for MAD2L1BP Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for MAD2L1BP gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for MAD2L1BP gene:
    Search GeneIP for patents involving MAD2L1BP

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for MAD2L1BP gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for MAD2L1BP  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MAD2L1BP   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MAD2L1BP  
     OriGene Protein Over-expression Lysate for MAD2L1BP   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for MAD2L1BP   OriGene 3'-UTR Clone for MAD2L1BP  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MAD2L1BP   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MAD2L1BP  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     OriGene Purified Protein for MAD2L1BP   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for MAD2L1BP   OriGene Custom Protein Services for MAD2L1BP  
     OriGene Custom Immunoassay Development  

         		 
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MAD2L1BP
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MAD2L1BP
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAD2L1BP
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MAD2L1BP
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAD2L1BP
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAD2L1BP
     GenScript Custom Purified and Recombinant Proteins Services for MAD2L1BP GenScript cDNA clones with any tag delivered in your preferred vector for MAD2L1BP
     GenScript Custom Assay Services for MAD2L1BP GenScript Custom Superior Antibodies Services for MAD2L1BP
     GenScript Custom overexpressing Cell Line Services for MAD2L1BP CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in MAD2L1BP promoter
     Search Chromatin IP Primers for MAD2L1BP
     RT2 qPCR Primer Assay in human, mouse, rat MAD2L1BP
     Search GNC Networks for MAD2L1BP
     SABiosciences Custom PCR Arrays for MAD2L1BP
     Search Tocris compounds for MAD2L1BP
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     MAD2L1BP antibodies
     MAD2L1BP proteins
     MAD2L1BP lysates
     Antibodies for MAD2L1BP
     See all of Abcam's Antibodies, Kits and Proteins for MAD2L1BP
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Recombinant Protein for MAD2L1BP




     MAD2L1BP Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for MAD2L1BP
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAD2L1BP
     SwitchGear 3'UTR luciferase reporter plasmids for MAD2L1BP
     SwitchGear Promoter luciferase reporter plasmids for MAD2L1BP
     ThermoFisher Antibodies for MAD2L1BP
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAD2L1BP
           
    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Copyright © 1996-2013 , Weizmann Institute of Science. All Rights Reserved.
    Hot genes      Disease genes      MAD2L1BP gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4