MACROD1 Gene
protein-coding GIFtS: 46
GCID: GC11M063767
|
|
MACRO domain containing 1
| |
Aliases
for MACROD1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| MACRO Domain Containing 11 2 | | LRP161 2 3 | | MACRO Domain-Containing Protein 12 3 | | O-Acetyl-ADP-Ribose Deacetylase MACROD12 | | EC 3.5.1.-3 | | Protein LRP163 |
Export aliases for MACROD1 gene to outside databasesPrevious GC identifers: GC11M063523 GC11M060094 |
Summaries
for MACROD1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: MACD1_HUMAN, Q9BQ69Function: Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysineresidues in histones and other proteins. Plays a role in estrogen signaling. Binds to androgen receptor (AR) andamplifies the transactivation function of AR in response to androgen. May play an important role in carcinogenesisand/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. Couldbe an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction. Could be involvedin invasive growth by down-regulating CDH1 in endometrial cancer cells. Enhances ESR1-mediated transcription activity
|
Genomic Views
for MACROD1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_167190.1
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the MACROD1 gene promoter:
Sp1 Bach2 NF-kappaB PPAR-gamma1 POU2F1 c-Myb PPAR-gamma2 NF-kappaB1
Other transcription factors
Search SABiosciences Chromatin IP Primers for MACROD1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MACROD1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11q11 Ensembl cytogenetic band: 11q13.1 HGNC cytogenetic band: 11q13.1MACROD1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M063767: view genomic region
(about GC identifiers)
Start:
|
63,766,030 bp from pter |
End:
|
63,933,585 bp from pter |
Size:
|
167,556 bases |
Orientation:
|
minus strand |
|
Proteins
for MACROD1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: MACD1_HUMAN, Q9BQ69 (See
protein sequence)Recommended Name: O-acetyl-ADP-ribose deacetylase MACROD1 Size: 325 amino acids; 35505 Da
Subunit: Interacts with ESR1; Interacts in a manner that is estrogen independent but is enhanced by estrogen. Interacts(via macro domain) with AR
Miscellaneous: Overexpression may promote MCF-7 cells proliferation. There is an approximate one-third increase of theinvasive capacity of MACROD1-overexpressing cells. The expression of CDH1 is repressed by MACROD1. Further analyzesdemonstrats that MACROD1 inhibits CDH1 transactivation in a dose dependent manner. Inhibition is abolished by estrogendeprivation, indicating that the down-regulation of CDH1 transcription by MACROD1 requires ESR1 mediation. Binding ofESR1 to the CDH1 promoter is antagonized by MACROD1, suggesting that MACROD1 could interfere with ESR1-mediatedtranscription. Knockdown of MACROD1 leads to impaired AR function and greatly attenuates the coactivation of AR byother AR coactivators such as UXT and NCOA1. This interference also markedly inhibits the androgen-stimulatedproliferation of androgen-sensitive LNCaP prostate cancer cells. MACROD1 knockdown does not significantly affect thegrowth rate of AR-negative PC-3 prostate cancer cells
Sequence caution: Sequence=AAH03188.1; Type=Erroneous initiation; Note=Translation N-terminally extended;Sequence=AAH03188.1; Type=Erroneous initiation;
1 PDB 3D structure from  and Proteopedia  for MACROD1:2X47 (3D)
Secondary accessions: Q9UH96Explore the universe of human proteins at neXtProt for MACROD1: NX_Q9BQ69
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BQ69
MACROD1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_054786.2
ENSEMBL proteins: ENSP00000255681
Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005739 | mitochondrion |
IEA | -- |
MACROD1 for ontologies About GeneDecksing
MACROD1 Antibody Products:
Assay Products for MACROD1: |
Protein
Domains /
Families
for MACROD1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
MACROD1 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry Q9BQ69ProtoNet protein and cluster: Q9BQ69 1 Blocks protein family: IPB002589 Protein of unknown function Appr-1
UniProtKB/Swiss-Prot: MACD1_HUMAN, Q9BQ69Similarity: Contains 1 Macro domain |
Function
for MACROD1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: MACD1_HUMAN, Q9BQ69Function: Deacetylates O-acetyl-ADP ribose, a signaling molecule generated by the deacetylation of acetylated lysineresidues in histones and other proteins. Plays a role in estrogen signaling. Binds to androgen receptor (AR) andamplifies the transactivation function of AR in response to androgen. May play an important role in carcinogenesisand/or progression of hormone-dependent cancers by feed-forward mechanism that activates ESR1 transactivation. Couldbe an ESR1 coactivator, providing a positive feedback regulatory loop for ESR1 signal transduction. Could be involvedin invasive growth by down-regulating CDH1 in endometrial cancer cells. Enhances ESR1-mediated transcription activityEnzyme regulation: Subject to competitive inhibition by the product ADP-riboseBiophysicochemical properties: Kinetic parameters: KM=373 uM for O-acetyl-ADP-ribose;Induction: Overexpressed by estrogens in breast cancer MCF-7 cells, probably via an activation of nuclear receptors forsteroids (ESR1 but not ESR2). Significantly increased by estrogens in ESR1-positive Ishikawa endometrial cancer cells.Up-regulated in 17-beta-estradiol-responsive BG-1 ovarian cancer cells but down-regulated in estrogen-resistant SKOV3ovarian cancer cells. Induced by androgenEnzyme Number (IUBMB): EC 3.5.1.-1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MACROD1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MACROD1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
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Synthesis Service for MACROD1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MACROD1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MACROD1 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
MACROD1 for ontologies About GeneDecksing
|
Pathways & Interactions
for MACROD1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for MACROD1
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
2 Interacting proteins for MACROD1 (Q9BQ691, 3 ENSP000002556814) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0042278 | purine nucleoside metabolic process |
IDA | -- |
MACROD1 for ontologies About GeneDecksing
|
Drugs & Compounds
for MACROD1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for MACROD1
Search CenterWatch for drugs/clinical trials and news about MACROD1 / MACD1
|
Transcripts
for MACROD1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for MACROD1 gene: NM_014067.3 Unigene Cluster for MACROD1: MACRO domain containing 1 Hs.602898 [show with all ESTs]Unigene Representative Sequence: AL8330178 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000255681(uc001nyh.3) ENST00000542105 ENST00000538042 ENST00000541041
ENST00000543422 ENST00000545464 ENST00000542359 ENST00000538595
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MACROD1 (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MACROD1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: MACROD1 (NM_014067) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MACROD1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MACROD1 |
Additional cDNA sequence: AF086206.1 AF202922.2 AL833017.1 BC000270.1 BC003188.1 BC007297.1 BC008316.1 15 DOTS entries: DT.91762287 DT.112929 DT.120741840 DT.75100064 DT.95335120 DT.40132281 DT.100751626 DT.75154589 DT.91762269 DT.120741897 DT.40316156 DT.446438 DT.97805164 DT.97825025 DT.97770464 24/136 AceView cDNA sequences (see all 136): BM710028 BF939311 BM920848 AI469181 AF086206 BQ186613 AF202922 BC000270 BM785075 BE501142 BE550014 BE466565 BM740794 BQ637198 BQ772767 BF590037 NM_014067 AI479573 BC007297 BM781625 BQ012354 BU616535 CA432714 BU072540
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for MACROD1 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 |
|---|
|
| SP1: | | | | | | | | | | | | | - | | | | | | | | | | | | |
| SP2: | | | | | | | | | - | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for MACROD1
|
Expression
for MACROD1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| MACROD1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAAGGAGATG
About this image
See MACROD1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MACROD1
SOURCE GeneReport for Unigene cluster: Hs.602898
SABiosciences Custom PCR Arrays for MACROD1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MACROD1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat MACROD1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MACROD1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MACROD1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MACROD1 |
Orthologs
for MACROD1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for MACROD1 gene from 8/27 species (see all 27) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
lizard
(Anolis carolinensis) |
Reptilia |
MACROD16 |
-- |
69(a) |
1 ↔ 1 |
GL343555.1(34990-49812) |
African clawed frog
(Xenopus laevis) |
Amphibia |
MGC686972 |
hypothetical protein MGC68697 |
73.63(n) |
|
BC060026.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
zgc659602 |
hypothetical protein MGC65960 |
71.86(n) |
|
393521 BC056529.1 |
honey bee
(Apis mellifera) |
Insecta |
---- |
-- |
39(a)15(a) |
1 ↔ manypossible ortholog |
Group1.34(61052-62323) GroupUn.882(32447-61334) |
worm
(Caenorhabditis elegans) |
Secernentea |
B0035.36 |
Protein B0035.3 |
44(a) |
1 → many |
IV(11314055-11315028) |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT2G406006 |
appr-1-p processing enzyme family protein |
28(a) |
possible ortholog |
2(16946870-16948561) |
rice
(Oryza sativa) |
Liliopsida |
-- |
appr-1-p processing enzyme family protein, putativ... |
32(a) |
possible ortholog |
3(12476735-12478853) |
E. coli
(Escherichia coli) |
Gamma proteobacteria |
ymdB6 |
O-acetyl-ADP-ribose deacetylase; RNase III inhibit... |
44(a) |
possible ortholog |
Chromosome(1105043-1105576) b1045 |
ENSEMBL Gene Tree for MACROD1 (if available)
TreeFam Gene Tree for MACROD1 (if available) |
Paralogs
for MACROD1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for MACROD1 gene
- GDAP22 MACROD22
1 SIMAP similar gene for MACROD1 using alignment to 1 protein entry: MACD1_HUMAN:MACROD2
MACROD1 for paralogs About GeneDecksing
|
Genomic Variants
for MACROD1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for MACROD1 (63766030 - 63933585 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for MACROD1
2 CNVs: 4750 4751 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MACROD1 |
|
Disorders
/ Diseases
for MACROD1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
MACROD1 for disorders About GeneDecksing
OMIM gene information: 610400
OMIM disorders: --
UniProtKB/Swiss-Prot: MACD1_HUMAN, Q9BQ69
Note=A chromosomal aberration involving MACROD1 is found in acute leukemia. Translocation t(11;21)(q13;q22)that forms a RUNX1-MACROD1 fusion protein
14  diseases for MACROD1: About MalaCardsestrogen resistance monocytic leukemia endometrial cancer ovarian carcinoma
leukemia t-cell leukemia ovarian cancer prostate cancer
breast cancer retinitis prostatitis tuberculosis
carcinoma mycobacterium tuberculosis
Export disorders for MACROD1 gene to outside databases
|
Publications
for MACROD1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for MACROD1 gene, integrated from 9 sources (see all 22):
(articles sorted by number of sources associating them with MACROD1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Differential induction of LRP16 by liganded and unliganded estrogen receptor alpha in SKOV3 ovarian carcinoma cells. (PubMed id 19403568)1, 2 Tian L.... Han W. (2009)
- The single-macro domain protein LRP16 is an essential cofactor of androgen receptor. (PubMed id 19022849)1, 2 Yang J....Han W.-D. (2009)
- Estrogenically regulated LRP16 interacts with estrogen receptor alpha and enhances the receptor's transcriptional activity. (PubMed id 17914104)1, 2 Han W.D....Mu Y.M. (2007)
- LRP16 is fused to RUNX1 in monocytic leukemia cell line with t(11;21)(q13;q22). (PubMed id 17532767)1, 2 Imagama S.... Naoe T. (2007)
- Mechanism of transcriptional regulation of LRP16 gene expression by 17-beta estradiol in MCF-7 human breast cancer cells. (PubMed id 15691879)1, 3 Zhao Y.L....Pan C.Y. (2005)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Up-regulation of LRP16 mRNA by 17beta-estradiol through activation of estrogen receptor alpha (ERalpha), but not ERbeta, and promotion of human breast cancer MCF-7 cell proliferation: a preliminary report. (PubMed id 12790785)1, 2 Han W.-D.... Pan C.-Y. (2003)
- The application of RACE technique to clone the full-length cDNA of a novel leukemia associated gene LRP16. (PubMed id 12578638)1, 2 Han W.-D.... Jin H.J. (2001)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- Identification of macrodomain proteins as novel O-acetyl-ADP-ribose deacetylases. (PubMed id 21257746)2 Chen D.... Ahel I. (2011)
|
External Searches for MACROD1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing MACROD1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing MACROD1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing MACROD1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for MACROD1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for MACROD1 gene:
Search GeneIP for patents involving MACROD1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for MACROD1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for MACROD1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for MACROD1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for MACROD1 | | | OriGene Protein Over-expression Lysate for MACROD1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for MACROD1 | | OriGene 3'-UTR Clone for MACROD1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for MACROD1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for MACROD1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MACROD1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MACROD1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MACROD1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MACROD1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MACROD1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MACROD1 |
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| | | | Search Tocris compounds for MACROD1 |
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 | | | MACROD1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MACROD1 |
|  |  |  | | | | Search ThermoFisher Antibodies for MACROD1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MACROD1 |
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