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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

MACC1 Gene

protein-coding   GIFtS: 50
GCID: GC07M020140

Metastasis Associated In Colon Cancer 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Metastasis Associated In Colon Cancer 11 2
SH3 Domain-Containing Protein 7a52 3
7A52
SH3BP4L2
Metastasis-Associated In Colon Cancer Protein 12
Putative Binding Protein 7a52

External Ids:    HGNC: 302151   Entrez Gene: 3463892   Ensembl: ENSG000001837427   OMIM: 6126465   UniProtKB: Q6ZN283   

Export aliases for MACC1 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for MACC1 Gene:
MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860)
pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility,
invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent
prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 (PubMed
19098908)).(supplied by OMIM, Mar 2009)

GeneCards Summary for MACC1 Gene: 
MACC1 (metastasis associated in colon cancer 1) is a protein-coding gene. Diseases associated with MACC1 include colon cancer, and lung adenocarcinoma. GO annotations related to this gene include growth factor activity. An important paralog of this gene is SH3BP4.

UniProtKB/Swiss-Prot: MACC1_HUMAN, Q6ZN28
Function: Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cell
motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and
metastasis in vivo




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007819.17  NC_018918.2  NT_079592.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the MACC1 gene promoter:
         c-Fos   AML1a   AP-1   Pbx1a   CUTL1   E4BP4   Gfi-1   c-Jun   NF-Y   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): MACC1 promoter sequence
   Search SABiosciences Chromatin IP Primers for MACC1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MACC1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p21.1   Ensembl cytogenetic band:  7p21.1   HGNC cytogenetic band: 7p15.3

MACC1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MACC1 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M020140:  view genomic region     (about GC identifiers)

Start:
20,174,278 bp from pter      End:
20,257,027 bp from pter
Size:
82,750 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 20,225,621-20,308,353     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MACC1_HUMAN, Q6ZN28 (See protein sequence)
Recommended Name: Metastasis-associated in colon cancer protein 1  
Size: 852 amino acids; 96639 Da
Subunit: Interacts with FASLG
Subcellular location: Cytoplasm. Nucleus. Note=Mainly found in the cytoplasm in non-metastasizing tumors
Sequence caution: Sequence=BAC87646.1; Type=Erroneous initiation; Sequence=EAW93719.1; Type=Erroneous gene model
prediction;
Secondary accessions: A8MUS5 B2RNR9 Q6ZQN8 Q7Z5A5

Explore the universe of human proteins at neXtProt for MACC1: NX_Q6ZN28

Explore proteomics data for MACC1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q6ZN28

  • MACC1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    MACC1 Protein Expression
    REFSEQ proteins: NP_877439.3  
    ENSEMBL proteins: 
     ENSP00000383185   ENSP00000328410   ENSP00000466864  

    Human Recombinant Protein Products for MACC1: 
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    Novus Biologicals MACC1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for MACC1 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--

    MACC1 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. ELISAs for MACC1 
    Cloud-Clone Corp. CLIAs for MACC1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR001452 SH3_domain
     IPR011511 SH3_2

    Graphical View of Domain Structure for InterPro Entry Q6ZN28

    ProtoNet protein and cluster: Q6ZN28

    UniProtKB/Swiss-Prot: MACC1_HUMAN, Q6ZN28
    Similarity: Contains 1 SH3 domain


    MACC1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MACC1_HUMAN, Q6ZN28
    Function: Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cell
    motility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and
    metastasis in vivo

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008083growth factor activity IEA--
         
    MACC1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for MACC1:
     G0/1 arrest  Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for MACC1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MACC1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MACC1 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MACC1 

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidMACC1 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MACC1

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for MACC1 (Q6ZN283 ENSP000003284104) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FASLGP480233, ENSP000003566944I2D: score=1 STRING: ENSP00000356694
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0051781positive regulation of cell division IEA--

    MACC1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for MACC1

    Search CenterWatch for drugs/clinical trials and news about MACC1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for MACC1 gene: 
    NM_182762.3  

    Unigene Cluster for MACC1:

    Metastasis associated in colon cancer 1
    Hs.598388  [show with all ESTs]
    Unigene Representative Sequence: NM_182762
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000400331(uc003sus.4 uc010kug.3) ENST00000332878 ENST00000589011
    ENST00000471019 ENST00000483317
    miRNA
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    8/44 QIAGEN miScript miRNA Assays for microRNAs that regulate MACC1 (see all 44):
    hsa-miR-323-3p hsa-miR-3130-5p hsa-miR-200a hsa-miR-500a hsa-miR-141 hsa-miR-629* hsa-miR-3116 hsa-miR-186
    SwitchGear 3'UTR luciferase reporter plasmidMACC1 3' UTR sequence
    Inhib. RNA
    Products:
         
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    GenScript: all cDNA clones in your preferred vector: MACC1 (NM_182762)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MACC1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MACC1
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MACC1
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MACC1

    Additional mRNA sequence: 

    AF086401.1 AJ313524.1 AK131400.1 AL359055.1 BC137090.1 BC144470.1 

    8 DOTS entries:

    DT.95302272  DT.91689187  DT.426227  DT.91997661  DT.102839597  DT.121126655  DT.121128236  DT.99983432 

    16 AceView cDNA sequences:

    BX282333 AJ313524 BX116250 BQ685117 AK128850 NM_182762 AK131400 AW451643 
    BI094701 BF335033 BF334738 BF358454 AI344046 BE144725 AI434612 BQ329753 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    MACC1 expression in normal human tissues (normalized intensities)      MACC1 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAAATAGAGT
    MACC1 Expression
    About this image


    MACC1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/7 selected tissues (see all 7) fully expand
     
     Lung (Respiratory System)
             alveolar macrophages   
     
     Inner Cell Mass (Early Embryonic Tissues)
             Line H9 (WA09)
     
     Kidney (Urinary System)
             Ureteric Bud
     
     Bone (Muscoskeletal System)
             Zeugopod Epiphyseal End
     
     Blood (Respiratory System)
             alveolar macrophages   

    See MACC1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for MACC1

    SOURCE GeneReport for Unigene cluster: Hs.598388

    UniProtKB/Swiss-Prot: MACC1_HUMAN, Q6ZN28
    Tissue specificity: Preferentially expressed in metastasizing tumors

        SABiosciences Custom PCR Arrays for MACC1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MACC1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for MACC1 gene from 5/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Macc11 , 5 metastasis associated in colon cancer 11, 5 81.86(n)1
    76.85(a)1
      12 (63.48 cM)5
    2384551  NM_001163136.11  NP_001156608.11 
     1194434105 
    chicken
    (Gallus gallus)
    Aves MACC11 metastasis associated in colon cancer 1 68.74(n)
    64.23(a)
      420604  XM_418705.3  XP_418705.3 
    lizard
    (Anolis carolinensis)
    Reptilia MACC16
    metastasis associated in colon cancer 1
    61(a)
    1 ↔ 1
    6(29079369-29152558)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.328362 Xenopus laevis transcribed sequence with weak similarity more 72.95(n)    BJ643085.1 
    zebrafish
    (Danio rerio)
    Actinopterygii macc11 metastasis associated in colon cancer 1 55.84(n)
    46.98(a)
      558777  NM_001199766.1  NP_001186695.1 


    ENSEMBL Gene Tree for MACC1 (if available)
    TreeFam Gene Tree for MACC1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for MACC1 gene
    SH3BP42  
    1 SIMAP similar gene for MACC1 using alignment to 1 protein entry:     MACC1_HUMAN:
    SH3BP4

    MACC1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/1639 SNPs in MACC1 are shown (see all 1639)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0426244
    ----see VAR_0426242 R T mis40--------
    rs1487419061,2
    --20174056(+) AAAACA/GTCTGA 1 -- int10--------
    rs9946711,2
    C,F,O,H--20174067(-) TCAATG/CCTCAC 1 -- int19Minor allele frequency- C:0.02MN NS EA NA WA 856
    rs1810304581,2
    --20174071(+) GCATTC/GAGTAT 1 -- int10--------
    rs69603371,2
    C,F,A,H--20174091(+) GGGAGT/CAAACC 1 -- int119Minor allele frequency- C:0.23NS EA NA WA CSA 2342
    rs1422784041,2
    --20174121(+) CTCTGA/CTAAGA 1 -- int10--------
    rs1512362481,2
    --20174411(+) CAGAGC/TCTTGA 1 -- ut310--------
    rs9946701,2
    C,F,A,H--20174433(-) CTTTTC/TTCTGT 1 -- ut316Minor allele frequency- T:0.08NS EA WA 658
    rs732764051,2
    C,F--20174446(+) AGCCAT/GAGATT 1 -- ut312Minor allele frequency- G:0.10WA 120
    rs119758511,2
    C,F,H--20174508(+) AAAACG/ATGATA 1 -- ut3113Minor allele frequency- A:0.07NS EA NA WA 1760

    HapMap Linkage Disequilibrium report for MACC1 (20174278 - 20257027 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 7 variations for MACC1:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2734101CNV Deletion23290073
    esv2734100CNV Deletion23290073
    nsv5650CNV Insertion18451855
    nsv520265CNV Loss19592680
    nsv887833CNV Loss21882294
    nsv830919CNV Loss17160897
    nsv887832CNV Loss21882294


    Human Gene Mutation Database (HGMD): MACC1
    SABiosciences Cancer Mutation PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing MACC1
    DNA2.0 Custom Variant and Variant Library Synthesis for MACC1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612646    OMIM disorders: --

    7 diseases for MACC1:    About MalaCards
    colon cancer    lung adenocarcinoma    peritonitis    colorectal cancer
    adenocarcinoma    hepatocellular carcinoma    lung cancer

    1 disease from the University of Copenhagen DISEASES database for MACC1:
    Colorectal cancer

    MACC1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): MACC1

    Export disorders for MACC1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for MACC1 gene, integrated from 9 sources (see all 34):
    (articles sorted by number of sources associating them with MACC1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening. (PubMed id 19807924)1, 2 Voss M....Janssen O. (2009)
    2. MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis. (PubMed id 19098908)1, 2 Stein U.... Schlag P.M. (2009)
    3. Metastasis-associated in colon cancer-1 upregulation p redicts a poor prognosis of gastric cancer, and promotes tumor cell proliferatio n and invasion. (PubMed id 23457029)1 Wang L....Liao W. (2013)
    4. MACC1 mRNA levels predict cancer recurrence after rese ction of colorectal cancer liver metastases. (PubMed id 23665971)1 Isella C....Muratore A. (2013)
    5. High intratumoral metastasis-associated in colon cance r-1 expression predicts poor outcomes of cryoablation therapy for advanced hepat ocellular carcinoma. (PubMed id 23414367)1 Yang Y.P....Hu K.Q. (2013)
    6. SNPs in the coding region of the metastasis-inducing g ene MACC1 and clinical outcome in colorectal cancer. (PubMed id 22838389)1 Schmid F....Stein U. (2012)
    7. MicroRNA-143 targets MACC1 to inhibit cell invasion an d migration in colorectal cancer. (PubMed id 22533346)1 Zhang Y....Jiang B. (2012)
    8. Correlation of MACC1 and MET expression in rectal canc er after neoadjuvant chemoradiotherapy. (PubMed id 22493396)1 Kawamura M....Kusunoki M. (2012)
    9. In vivo imaging of colorectal cancer growth and metast asis by targeting MACC1 with shRNA in xenografted mice. (PubMed id 22484916)1 Pichorner A....Stein U. (2012)
    10. [Expression and clinical significance of metastasis-as sociated in colon cancer 1 (MACC1) in HBV-related hepatocellular carcinoma]. (PubMed id 23291068)1 Chang X.J....Yang Y.P. (2012)

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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 346389 HGNC: 30215 AceView: 7A5 Ensembl:ENSG00000183742 euGenes: HUgn346389
    ECgene: MACC1 H-InvDB: MACC1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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    About This Section
    NameDescription
    PharmGKB entry for MACC1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
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    Patent Information for MACC1 gene:
    Search GeneIP for patents involving MACC1

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