MACC1 Gene
protein-coding GIFtS : 49
GCID: GC07 M020140
metastasis associated in colon cancer 1
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Aliasesfor MACC1 gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Metastasis Associated In Colon Cancer 1 1 2 7A51 2 SH3BP4L1 2 SH3 Domain-Containing Protein 7a52 3 Metastasis-Associated In Colon Cancer Protein 12 Putative Binding Protein 7a52
Export aliases for MACC1 gene to outside databases
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Summariesfor MACC1 gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section Entrez Gene summary for MACC1 : MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 (PubMed 19098908)).(supplied by OMIM, Mar 2009) UniProtKB/Swiss-Prot: MACC1_HUMAN, Q6ZN28 Function : Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cellmotility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genomic Viewsfor MACC1 gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000007.13 NC_018918.1 NT_007819.17 NT_079592.2 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the MACC1 gene promoter: c-Fos AML1a AP-1 Pbx1a CUTL1 E4BP4 Gfi-1 c-Jun NF-Y Other transcription factors Search SABiosciences Chromatin IP Primers for MACC1 Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MACC1
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 7p21.1 Ensembl cytogenetic band: 7p21.1 HGNC cytogenetic band: 7p15.3 MACC1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 7 GeneLoc Exon Structure
GeneLoc location for GC07M020140: view genomic region
(about GC identifiers )
Start:
20,174,278 bp from pter
End:
20,257,027 bp from pter
Size:
82,750 bases
Orientation:
minus strand
1 alternative location : Chr 7-,CRA_TCAG 20,225,621-20,308,353
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Proteinsfor MACC1 gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: MACC1_HUMAN, Q6ZN28 (See
protein sequence )Recommended Name: Metastasis-associated in colon cancer protein 1 Size : 852 amino acids; 96639 Da
Subunit : Interacts with FASLG
Subcellular location : Cytoplasm. Nucleus. Note=Mainly found in the cytoplasm in non-metastasizing tumors
Sequence caution : Sequence=BAC87646.1; Type=Erroneous initiation; Sequence=EAW93719.1; Type=Erroneous gene modelprediction;
Secondary accessions : A8MUS5 B2RNR9 Q6ZQN8 Q7Z5A5Explore the universe of human proteins at neXtProt for MACC1: NX_Q6ZN28 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q6ZN28 MACC1 Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins: NP_877439.3 ENSEMBL proteins: ENSP00000383185 ENSP00000328410 ENSP00000466864 Human Recombinant Protein Products: Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view) : About this table
MACC1 for ontologies About GeneDecksing MACC1 Antibody Products: Assay Products for MACC1:
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Protein
Domains / Familiesfor MACC1 gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
MACC1 for domains About GeneDecksing 2 InterPro domains/families :
Graphical View of Domain Structure for InterPro Entry Q6ZN28 ProtoNet protein and cluster: Q6ZN28
UniProtKB/Swiss-Prot: MACC1_HUMAN, Q6ZN28 Similarity : Contains 1 SH3 domain
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Functionfor MACC1 gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: MACC1_HUMAN, Q6ZN28 Function : Acts as a transcription activator for MET and as a key regulator of HGF-MET signaling. Promotes cellmotility, proliferation and hepatocyte growth factor (HGF)-dependent scattering in vitro and tumor growth and metastasis in vivo
Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for MACC1 (see all 2 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for MACC1OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: MACC1 (NM_182762 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MACC1 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat MACC1
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MACC1
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0008083 growth factor activity
IEA --
MACC1 for ontologies About GeneDecksing 2 GenomeRNAi human phenotypes for MACC1 :
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Pathways & Interactionsfor MACC1 gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for MACC1 STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)1 Interacting protein for MACC1 (Q6ZN28 3 ENSP00000328410 4 ) via UniProtKB, MINT, STRING , and/or I2D About this table Gene Ontology (GO): 3 biological process terms (GO ID links to tree view) : About this table
GO ID Qualified GO term Evidence PubMed IDs GO:0006351 transcription, DNA-dependent
IEA -- GO:0006355 regulation of transcription, DNA-dependent
IEA -- GO:0051781 positive regulation of cell division
IEA --
MACC1 for ontologies About GeneDecksing
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Drugs & Compoundsfor MACC1 gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for MACC1 Search CenterWatch for drugs/clinical trials and news about MACC1
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Transcriptsfor MACC1 gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
OriGene ,
SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for MACC1 gene: NM_182762.3 Unigene Cluster for MACC1:
Metastasis associated in colon cancer 1 Hs.598388 [show with all ESTs ] Unigene Representative Sequence: NM_182762 5 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000400331 (uc003sus.4 uc010kug.3 ) ENST00000332878 ENST00000589011 ENST00000471019 ENST00000483317 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for MACC1 (see all 2 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for MACC1OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector: MACC1 (NM_182762 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for MACC1 Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat MACC1
Additional cDNA sequence: AF086401.1 AJ313524.1 AK131400.1 AL359055.1 BC137090.1 BC144470.1
8 DOTS entries : DT.95302272 DT.91689187
DT.426227 DT.91997661 DT.102839597 DT.121126655 DT.121128236 DT.99983432 16 AceView cDNA sequences :
BX116250 BX282333 AJ313524 AK131400 AK128850 BQ685117 NM_182762 AW451643 BF335033 BI094701 BF334738 BE144725 BF358454 AI344046 AI434612 BQ329753 GeneLoc Exon Structure
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Expression for MACC1 gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section MACC1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: AAAATAGAGT
About this image MACC1 expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table 1 LifeMap In Vivo Development Anatomical Compartment/Cell Tissue Anatomical Compartment
Cell Category (developmental path) Bone Zeugopod Epiphyseal End Bone Expression: Positive Negative
Selective markerExperimental details:
Curated
Microarrays
In-situ hybridization
Stem Cell Differentiation: 2 LifeMap Cells Name Category Line H9 (WA09) (Embryonic Stem Cell)Early Embryo, Inner Cell Mass Human kidney epithelial cell spheroids (Kidney spheroids for... )
See MACC1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for MACC1 SOURCE GeneReport for Unigene cluster: Hs.598388 UniProtKB/Swiss-Prot: MACC1_HUMAN, Q6ZN28 Tissue specificity : Preferentially expressed in metastasizing tumors SABiosciences Custom PCR Arrays for MACC1 Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for MACC1Browse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat MACC1 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat MACC1 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat MACC1 In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MACC1
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Orthologsfor MACC1 gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of chordates.
Orthologs for MACC1 gene from 4/12 species (see all 12 ) About this table
Organism
Taxonomic classification
Gene
Description
Human Similarity
Orthology Type
Details
chicken (Gallus gallus)
Aves
MACC11
metastasis associated in colon cancer 1
68.74(n) 64.23(a)
 
420604 XM_418705.3 XP_418705.3
lizard (Anolis carolinensis)
Reptilia
MACC16
--
62(a)
1 ↔ 1
6(29083541-29105343)
African clawed frog (Xenopus laevis)
Amphibia
Xl.328362
Xenopus laevis transcribed sequence with weak similarity more
72.95(n)
 
BJ643085.1
zebrafish (Danio rerio)
Actinopterygii
macc11
metastasis associated in colon cancer 1
55.84(n) 46.98(a)
 
558777 NM_001199766.1 NP_001186695.1
ENSEMBL Gene Tree for MACC1 (if available)TreeFam Gene Tree for MACC1 (if available)
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Paralogsfor MACC1 gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for MACC1 gene SH3BP4 2 1 SIMAP similar gene for MACC1 using alignment to 1 protein entry: MACC1_HUMAN :SH3BP4
MACC1 for paralogs About GeneDecksing
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genomic Variantsfor MACC1 gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 7 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for MACC1 (20174278 - 20257027 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 2 variations for MACC1 2 CNVs : 52187 52188 Human Gene Mutation Database (HGMD) : MACC1 SABiosciences Cancer Mutation PCR Assays
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Disorders
/ Diseasesfor MACC1 gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
MACC1 for disorders About GeneDecksing
OMIM gene information: 612646
OMIM disorders : --8 diseases for MACC1 : About MalaCards colon cancer lung adenocarcinoma ovarian carcinoma hepatocellular carcinoma peritonitis colorectal cancer adenocarcinoma carcinoma 1 disease from the University of Copenhagen DISEASES database for MACC1 :Colorectal cancer Export disorders for MACC1 gene to outside databases
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Publicationsfor MACC1 gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for MACC1 gene, integrated from 9 sources (see all 28 ): (articles sorted by number of sources associating them with MACC1) Utopia : connect your pdf to the dynamic world of online information
Identification of SH3 domain interaction partners of human FasL (CD178) by phage display screening. (PubMed id 19807924) 1 , 2 Voss M....Janssen O. (2009) MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis. (PubMed id 19098908) 1 , 2 Stein U.... Schlag P.M. (2009) Integrative marker analysis allows risk assessment for metastasis in stage II colon cancer. (PubMed id 23095620) 1 Nitsche U....Janssen K.P. (2012) A common variant of the MACC1 gene is significantly as sociated with overall survival in colorectal cancer patients. (PubMed id 22251819) 1 Lang A.H....Muendlein A. (2012) MiR-1 downregulation cooperates with MACC1 in promotin g MET overexpression in human colon cancer. (PubMed id 22179665) 1 Migliore C....Giordano S. (2012) [Prognostic value of MACC1 and c-met expressions in no n-small cell lung cancer]. (PubMed id 22814258) 1 Hu X....Liu Y. (2012) MicroRNA-143 targets MACC1 to inhibit cell invasion an d migration in colorectal cancer. (PubMed id 22533346) 1 Zhang Y....Jiang B. (2012) Correlation of MACC1 and MET expression in rectal canc er after neoadjuvant chemoradiotherapy. (PubMed id 22493396) 1 Kawamura M....Kusunoki M. (2012) In vivo imaging of colorectal cancer growth and metast asis by targeting MACC1 with shRNA in xenografted mice. (PubMed id 22484916) 1 Pichorner A....Stein U. (2012) Effects of metastasis-associated in colon cancer 1 in hibition by small hairpin RNA on ovarian carcinoma OVCAR-3 cells. (PubMed id 21923915) 1 Zhang R....Huang H. (2011)
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
External Searches for MACC1 gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Genome Databases showing MACC1 gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Other Databases showing MACC1 gene
(According to HUGE )
About This Section --
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Specialized Databases showing MACC1 gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for MACC1 Pharmacogenomics, SNPs, Pathways
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
About This Section Patent Information for MACC1 gene: Search GeneIP for patents involving MACC1 GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
Jump to Section...
Aliases
Databases
Disorders / Diseases
Domains / Families
Drugs / Compounds
Expression
Function
Genomic Views
Intellectual Property
Orthologs
Paralogs
Pathways / Interactions
Products
Proteins
Publications
Search Box
Summaries
Transcripts
Variants
TOP
BOTTOM
Productsfor MACC1 gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
OriGene Antibodies for MACC1 OriGene shRNA RFP for MACC1 OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for MACC1 OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for MACC1 OriGene Protein Over-expression Lysate for MACC1 Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for MACC1 OriGene 3'-UTR Clone for MACC1 OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for MACC1 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for MACC1 Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs OriGene Purified Protein for MACC1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for MACC1 OriGene Custom Protein Services for MACC1 OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MACC1 Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MACC1 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MACC1 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat MACC1 QIAGEN QuantiFast Probe-based Assays in human , mouse , rat MACC1 QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat MACC1
Search Tocris compounds for MACC1
MACC1 Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MACC1
ThermoFisher Antibodies for MACC1
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat MACC1
Jump to Section...
Aliases for MACC1
Databases for MACC1
Disorders / Diseases for MACC1
Domains / Families for MACC1
Drugs / Compounds for MACC1
Expression for MACC1
Function for MACC1
Genomic Views for MACC1
Intellectual Property for MACC1
Orthologs for MACC1
Paralogs for MACC1
Pathways / Interactions for MACC1
Products for MACC1
Proteins for MACC1
Publications for MACC1
Search Box for MACC1
Summaries for MACC1
Transcripts for MACC1
Variants for MACC1
TOP
BOTTOM