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Aliases for MAB21L3 Gene

Aliases for MAB21L3 Gene

  • Mab-21-Like 3 (C. Elegans) 2 3
  • C1orf161 3 4
  • Chromosome 1 Open Reading Frame 161 2

External Ids for MAB21L3 Gene

Previous HGNC Symbols for MAB21L3 Gene

  • C1orf161

Previous GeneCards Identifiers for MAB21L3 Gene

  • GC01P116655
  • GC01P116111

Summaries for MAB21L3 Gene

GeneCards Summary for MAB21L3 Gene

MAB21L3 (Mab-21-Like 3 (C. Elegans)) is a Protein Coding gene. An important paralog of this gene is MAB21L1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MAB21L3 Gene

Genomics for MAB21L3 Gene

Genomic Location for MAB21L3 Gene

116,075,792 bp from pter
116,135,240 bp from pter
59,449 bases
Plus strand

Genomic View for MAB21L3 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for MAB21L3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MAB21L3 Gene

No data available for Regulatory Elements for MAB21L3 Gene

Proteins for MAB21L3 Gene

  • Protein details for MAB21L3 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein mab-21-like 3
    Protein Accession:
    Secondary Accessions:
    • Q5TDL7

    Protein attributes for MAB21L3 Gene

    362 amino acids
    Molecular mass:
    42357 Da
    Quaternary structure:
    No Data Available

neXtProt entry for MAB21L3 Gene

Proteomics data for MAB21L3 Gene at MOPED

Post-translational modifications for MAB21L3 Gene

No Post-translational modifications

Other Protein References for MAB21L3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MAB21L3 Gene

Domains & Families for MAB21L3 Gene

Protein Domains for MAB21L3 Gene


Suggested Antigen Peptide Sequences for MAB21L3 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the mab-21 family.
  • Belongs to the mab-21 family.
genes like me logo Genes that share domains with MAB21L3: view

No data available for Gene Families for MAB21L3 Gene

Function for MAB21L3 Gene

Gene Ontology (GO) - Molecular Function for MAB21L3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with MAB21L3: view

Phenotypes for MAB21L3 Gene

genes like me logo Genes that share phenotypes with MAB21L3: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MAB21L3

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MAB21L3 Gene

Localization for MAB21L3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for MAB21L3 Gene

Pathways & Interactions for MAB21L3 Gene

SuperPathways for MAB21L3 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MAB21L3 Gene


No data available for Pathways by source and SIGNOR curated interactions for MAB21L3 Gene

Drugs & Compounds for MAB21L3 Gene

No Compound Related Data Available

Transcripts for MAB21L3 Gene

mRNA/cDNA for MAB21L3 Gene

(5) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for MAB21L3 Gene

Mab-21-like 3 (C. elegans):
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for MAB21L3

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for MAB21L3 Gene

No ASD Table

Relevant External Links for MAB21L3 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MAB21L3 Gene

mRNA expression in normal human tissues for MAB21L3 Gene

mRNA differential expression in normal tissues according to GTEx for MAB21L3 Gene

This gene is overexpressed in Esophagus - Mucosa (x12.2), Liver (x5.9), and Vagina (x5.9).

SOURCE GeneReport for Unigene cluster for MAB21L3 Gene Hs.376194

genes like me logo Genes that share expression patterns with MAB21L3: view

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for MAB21L3 Gene

Orthologs for MAB21L3 Gene

This gene was present in the common ancestor of animals.

Orthologs for MAB21L3 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MAB21L3 35
  • 82.4 (n)
  • 78.03 (a)
MAB21L3 36
  • 75 (a)
(Canis familiaris)
Mammalia MAB21L3 35
  • 85.08 (n)
  • 83.43 (a)
MAB21L3 36
  • 76 (a)
(Mus musculus)
Mammalia Mab21l3 35
  • 79.65 (n)
  • 76.52 (a)
Mab21l3 16
Mab21l3 36
  • 65 (a)
(Pan troglodytes)
Mammalia MAB21L3 35
  • 99.17 (n)
  • 98.9 (a)
MAB21L3 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Mab21l3 35
  • 79.93 (n)
  • 76.52 (a)
(Monodelphis domestica)
Mammalia MAB21L3 36
  • 61 (a)
(Ornithorhynchus anatinus)
Mammalia MAB21L3 36
  • 54 (a)
(Gallus gallus)
Aves MAB21L3 35
  • 71.43 (n)
  • 66.39 (a)
MAB21L3 36
  • 58 (a)
(Anolis carolinensis)
Reptilia MAB21L3 36
  • 65 (a)
(Danio rerio)
Actinopterygii mab21l3 35
  • 61.72 (n)
  • 57.7 (a)
mab21l3 36
  • 54 (a)
(Caenorhabditis elegans)
Secernentea mab-21 36
  • 21 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 22 (a)
Species with no ortholog for MAB21L3:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for MAB21L3 Gene

Gene Tree for MAB21L3 (if available)
Gene Tree for MAB21L3 (if available)

Paralogs for MAB21L3 Gene

Paralogs for MAB21L3 Gene

genes like me logo Genes that share paralogs with MAB21L3: view

Variants for MAB21L3 Gene

Sequence variations from dbSNP and Humsavar for MAB21L3 Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs911222 -- 116,098,654(+) AAGGA(C/T)GGGGT intron-variant
rs911223 -- 116,098,752(+) GATGC(C/T)TGAAT intron-variant
rs911224 -- 116,098,903(+) TCCTG(A/C)GTAAA intron-variant
rs927201 -- 116,099,537(-) TCCCA(A/G)TAGTG intron-variant
rs983760 -- 116,134,047(+) GCTTC(C/G)CTGGT utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for MAB21L3 Gene

Variant ID Type Subtype PubMed ID
esv27976 CNV Loss 19812545
nsv831126 CNV Gain 17160897

Variation tolerance for MAB21L3 Gene

Residual Variation Intolerance Score: 70.67% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.35; 26.64% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for MAB21L3 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MAB21L3 Gene

Disorders for MAB21L3 Gene

Relevant External Links for MAB21L3

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with MAB21L3: view

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MAB21L3 Gene

Publications for MAB21L3 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 2 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 67
  3. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 67
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 67
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 67

Products for MAB21L3 Gene

Sources for MAB21L3 Gene

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