MAATS1 Gene

Aliases
for MAATS1 gene

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
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Summaries
for MAATS1 gene

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Genomic Views
for MAATS1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:

NC_000003.11  NT_005612.17  NC_018914.2  

Browse SwitchGear Promoter luciferase reporter plasmids

DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MAATS1

MAATS1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P119422:  view genomic region     (about GC identifiers)

Proteins
for MAATS1 gene

(According to ¹UniProtKB, HORDE, ²neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, antibodies-online, and/or GeneTex,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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Explore the universe of human proteins at neXtProt for MAATS1: NX_Q7Z4T9

Explore proteomics data for MAATS1 at MOPED

Post-translational modifications: 

MAATS1 Human Recombinant Protein Products:

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	Browse Proteins at Cloud-Clone Corp.
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	antibodies-online proteins for MAATS1 (2 products)
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MAATS1 Antibody Products:

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	ThermoFisher Antibodies for MAATS1
	antibodies-online antibodies for MAATS1 (16 products)

MAATS1 Assay Products:

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	Browse Enzo Life Sciences for kits & assays
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	Search eBioscience for ELISAs for MAATS1
	Search antibodies-online for kits for MAATS1

Domains /
Families
for MAATS1 gene

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GenesLikeMe)
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ProtoNet protein and cluster: Q7Z4T9

Function
for MAATS1 gene

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
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     Gene Ontology (GO): 2 molecular function terms:    About this table

genOway: Develop your customized and physiologically relevant rodent model for MAATS1

miRNA Products:		Block miRNA regulation of human, mouse, rat MAATS1 using miScript Target Protectors
		Search for qRT-PCR Assays for microRNAs that regulate MAATS1
		SwitchGear 3'UTR luciferase reporter plasmid: MAATS1 3' UTR sequence

Inhib. RNA Products:		OriGene RNAi products in human, mouse, rat for MAATS1
		Predesigned siRNA for gene silencing in human, mouse, rat MAATS1

Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for MAATS1

Clone Products:		OriGene clones in human, mouse for MAATS1 (see all 7) OriGene ORF clones in mouse, rat for MAATS1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript Custom all cDNA clones Services for MAATS1
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for MAATS1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAATS1

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for MAATS1
		Browse ESI BIO Cell Lines and PureStem Progenitors for MAATS1

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAATS1

Localization
for MAATS1 gene

(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
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Gene Ontology (GO): 1 cellular component term:    About this table

Pathways & Interactions
for MAATS1 gene

(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GenesLikeMe, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene, Sets of similar genes according to GenesLikeMe)
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Gene Ontology (GO): 1 biological process term:    About this table

Drugs & Compounds
for MAATS1 gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, Sets of similar genes according to GenesLikeMe)
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Transcripts
for MAATS1 gene

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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Expression
for MAATS1 gene

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GenesLikeMe, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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MAATS1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: --

About this image

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for MAATS1
		Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat MAATS1
		QuantiTect SYBR Green Assays in human, mouse, rat MAATS1
		QuantiFast Probe-based Assays in human, mouse, rat MAATS1

In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAATS1

Orthologs
for MAATS1 gene

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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Paralogs
for MAATS1 gene

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68,Sets of similar genes according to GenesLikeMe)
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Paralogs for MAATS1 gene

1 SIMAP similar gene for MAATS1 using alignment to 5 protein entries:     MAAT1_HUMAN (see all proteins):

C3orf15

Find genes that share paralogs with MAATS1           About GenesLikeMe

Genomic Variants
for MAATS1 gene

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for MAATS1 (see all 1302)    About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 3 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs2003337091,2	C	--	119419914(+)	CAGATC/TGACCC	1	--	us2k1		0	--	--	--	--
rs1147812881,2	C,F	--	119420013(+)	TTACCA/GGTGCA	1	--	us2k1		2		WA NA	238
rs1166492441,2	F	--	119420019(+)	GTGCAT/CGCAGC	1	--	us2k1		1		WA	118
rs1511468841,2		--	119420024(+)	TGCAGC/GTCCCA	1	--	us2k1		0	--	--	--	--
rs1146262141,2	C,F	--	119420073(+)	CTCACG/ACAGAC	1	--	us2k1		1		NA	120
rs1401256881,2		--	119420082(+)	ACCCTC/GTTAGA	1	--	us2k1		0	--	--	--	--
rs1814347581,2		--	119420089(+)	TAGAGC/TTGTAT	1	--	us2k1		0	--	--	--	--
rs1861772691,2		--	119420122(+)	GCTCAC/TTCCGG	1	--	us2k1		0	--	--	--	--
rs731920401,2	C,F	--	119420209(+)	TGAGCG/AGTTCT	1	--	us2k1		5		NA CSA WA	243
rs1131893941,2	C	--	119420394(+)	TTCCCT/-TTACT	1	--	us2k1		1		CSA	2

HapMap Linkage Disequilibrium report for MAATS1 (119421869 - 119485949 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for MAATS1: --

Site Specific Mutation Identification with PCR Assays

SeqTarget long-range PCR primers for resequencing MAATS1

DNA2.0 Custom Variant and Variant Library Synthesis for MAATS1

Disorders / Diseases
for MAATS1 gene

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB, Sets of similar genes according to GenesLikeMe)
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Publications
for MAATS1 gene

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for MAATS1 gene, integrated from 10 sources (see all 12): (articles sorted by number of sources associating them with MAATS1)

Utopia: connect your pdf to the dynamic world of online information

1. AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex between AMY-1, A-kinase anchor protein 84 and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase. (PubMed id 12223483)^{1, 2, 3, 9} Yukitake H.... Ariga H. (J. Biol. Chem. 2002)
2. Structure and characterization of AAT-1 isoforms. (PubMed id 15863901)^{1, 2, 9} Matsuda E.... Ariga H. (Biol. Pharm. Bull. 2005)
3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (Nat. Genet. 2004)
4. Are polymorphic markers within the alpha-1-antitrypsin gene associated with risk of human immunodeficiency virus disease? (PubMed id 14551891)^{1, 3} Hayes V.M. and Gardiner-Garden M. (J. Infect. Dis. 2003)
5. Protein interaction discovery using parallel analysis of translated ORFs (PLATO). (PubMed id 23503679)¹ Zhu J....Elledge S.J. (Nat. Biotechnol. 2013)
6. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (BMC Genomics 2007)
7. The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)² Muzny D.M....Gibbs R.A. (Nature 2006)
8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S.... Malek J. (Genome Res. 2004)
9. Progression of atherosclerosis is associated with variation in the alpha1-antitrypsin gene. (PubMed id 12692006)¹ Talmud P.J....SyvAonne M. (Arterioscler. Thromb. Vasc. Biol. 2003)
10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

External Searches for MAATS1 gene

Genome Databases showing MAATS1 gene

Other Databases showing MAATS1 gene

Specialized Databases showing MAATS1 gene

Products
for MAATS1 gene

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, eBioscience, antibodies-online, GeneTex, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from genOway)
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