Home
GeneCards Guide
Suite
- MalaCards
- GeneALaCart
- GeneDecks
- GeneIP
- GeneLoc
Terms and Conditions
- Terms of Use
- 3rd Party Notice
About Us
- GeneCards Team
- Our Publications
- Citing GeneCards
- Licensing Agreement
- Weizmann Institute
- LifeMap Sciences Inc
User Feedback
Mirror sites

Set Analyses:

Generates a file of GeneCards annotations for your list of genes

Advanced Search

Search By

Section (entire)

for

All GeneCards Within gene subset (to enable gene prioritization):
or upload a file of gene symbols

Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

MAATS1 Gene

protein-coding GIFtS: 43
GCID: GC03P119422

MYCBP-Associated, Testis Expressed 1

(Previous names: chromosome 3 open reading frame 15, MYCBP/AMY-1-associated,...)
(Previous symbol: C3orf15)

1 related disease
at

MalaCards

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, ¹⁰fRNAdb, ¹²H-InvDB, ¹³NCBI, ¹⁴NONCODE, and/or ¹⁵RNAdb)
About This Section

Aliases
MYCBP-Associated, Testis Expressed 1¹ ²		AAT-1² ³
C3orf15¹ ² ³ ⁵		MYCBP/AMY-1-Associated Testis-Expressed Protein 1² ³
AMY-1-Associating Protein Expressed In Testis 1¹ ² ³		Chromosome 3 Open Reading Frame 15¹
AAT1² ³ ⁵		AAT1-alpha²
MYCBP/AMY-1-Associated, Testis Expressed 1¹ ²		AAT1alpha²
MYCBP-Binding Protein¹ ²		SPATA26²
Spermatogenesis Associated 26¹ ²		Protein MAATS1²

External Ids:	HGNC: 24010¹	Entrez Gene: 89876²	Ensembl: ENSG00000183833⁷	OMIM: 609910⁵	UniProtKB: Q7Z4T9³

Export aliases for MAATS1 gene to outside databases

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for MAATS1 Gene:

MAATS1 (MYCBP-associated, testis expressed 1) is a protein-coding gene. Diseases associated with MAATS1 include atherosclerosis. GO annotations related to this gene include protein binding.

UniProtKB/Swiss-Prot: MAAT1_HUMAN, Q7Z4T9

Function: Isoform 4 may play a role in spermatogenesis

Gene Wiki entry for MAATS1 (C3orf15) Gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000003.11 NT_005612.16 NC_018914.2

Regulatory elements:

Search SABiosciences Regulatory transcription factor binding sites for MAATS1
Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids

Search SABiosciences Chromatin IP Primers for MAATS1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAATS1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q12-q13.3 Ensembl cytogenetic band: 3q13.33 HGNC cytogenetic band: 3q12-q13.3

MAATS1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MAATS1 gene location

GeneLoc information about chromosome 3 GeneLoc Exon Structure

GeneLoc location for GC03P119422: view genomic region (about GC identifiers)

Start:	119,421,869 bp from pter	End:	119,485,949 bp from pter
Size:	64,081 bases	Orientation:	plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE ¹MOPED, ²PaxDb, and ³MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: MAAT1_HUMAN, Q7Z4T9 (See protein sequence)

Recommended Name: Protein MAATS1

Size: 603 amino acids; 70999 Da

Subunit: Interacts with MYCBP and AKAP1. Isoform 4 is part of a complex containing MYCBP, AKAP1 and PRKAR2B. Isoform 3

does not interact with MYCBP

Subcellular location: Cytoplasm. Mitochondrion. Note=Isoform 4 is found in the mitochondria and localized in the neck

of the sperm

Secondary accessions: A0AVK2 A8K1J9 B3KP23 B4DG52 B4DZ14 C9JUG4 Q68DX2 Q8TD41 Q96A45 Q96JE8

Alternative promoter usage, Alternative splicing: 8 isoforms: Q7Z4T9-1 Q7Z4T9-2 Q7Z4T9-3 Q7Z4T9-4 Q7Z4T9-6 Q7Z4T9-7 Q7Z4T9-8 Q7Z4T9-5

(May be produced by alternative promoter usage)

Explore the universe of human proteins at neXtProt for MAATS1: NX_Q7Z4T9

Explore proteomics data for MAATS1 at MOPED

Post-translational modifications:

UniProtKB: Isoform 4 is phosphorylated by PKA

View modification sites using PhosphoSitePlus

View neXtProt modification sites for NX_Q7Z4T9

MAATS1 Protein expression data from MOPED¹, PaxDb² and MAXQB³ : About this image

REFSEQ proteins: NP_203528.2

ENSEMBL proteins:

ENSP00000273390 ENSP00000419520 ENSP00000419489 ENSP00000418601 ENSP00000419972

ENSP00000419554

Human Recombinant Protein Products for MAATS1:

	Browse Purified and Recombinant Proteins at EMD Millipore
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	OriGene Purified Protein for MAATS1 OriGene Protein Over-expression Lysate for MAATS1 OriGene MassSpec for MAATS1 OriGene Custom Protein Services for MAATS1
	GenScript Custom Purified and Recombinant Proteins Services for MAATS1
	Novus Biologicals MAATS1 Protein Novus Biologicals MAATS1 Lysates
	Browse Sino Biological Recombinant Proteins Browse Sino Biological Cell Lysates
	Browse ProSpec Recombinant Proteins
	Browse Proteins at Cloud-Clone Corp.

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005739	mitochondrion	IEA	--

MAATS1 for ontologies About GeneDecksing

MAATS1 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for MAATS1
	GenScript Custom Superior Antibodies Services for MAATS1
	Novus Biologicals MAATS1 Antibodies
	Abcam antibodies for MAATS1
	Browse Antibodies at Cloud-Clone Corp.
	ThermoFisher Antibodies for MAATS1
	LSBio Antibodies in human, mouse, rat for MAATS1

Assay Products for MAATS1:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Assay Services for MAATS1
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for MAATS1
	Browse Enzo Life Sciences for kits & assays
	Browse ELISAs at Cloud-Clone Corp. Browse CLIAs at Cloud-Clone Corp.

(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

1 InterPro protein domain:

IPR026720 AAT1

Graphical View of Domain Structure for InterPro Entry Q7Z4T9

ProtoNet protein and cluster: Q7Z4T9

MAATS1 for domains About GeneDecksing

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: MAAT1_HUMAN, Q7Z4T9

Function: Isoform 4 may play a role in spermatogenesis

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004014	adenosylmethionine decarboxylase activity	--	--
GO:0005515	protein binding	IPI	12223483

MAATS1 for ontologies About GeneDecksing

Animal Models:

inGenious Targeting Laboratory - Custom generated mouse model solutions for MAATS1

inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MAATS1

miRNA Products:
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MAATS1
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate MAATS1
		SwitchGear 3'UTR luciferase reporter plasmid: MAATS1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for MAATS1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MAATS1
		Sirion Biotech Custom design and validation of potent shRNA sequences against MAATS1

Gene Editing Products:			DNA2.0 Custom Protein Engineering Service for MAATS1
			Sirion Biotech Customized adenovirus for overexpression of MAATS1 Customized adenovirus for potent knockdown of MAATS1

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene clones in human, mouse for MAATS1 (see all 7) OriGene ORF clones in mouse, rat for MAATS1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript Custom all cDNA clones Services for MAATS1
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for MAATS1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAATS1

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for MAATS1
		Search LifeMap BioReagents cell lines for MAATS1
		Sirion Biotech Customized stable knockdown cell line services for MAATS1 Customized inducible knockdown cell line services for MAATS1 Customized stable overexpressing cell line services for MAATS1 Customized inducible overexpressing cell line services for MAATS1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAATS1

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for MAATS1

STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

4 Interacting proteins for MAATS1 (Q7Z4T9^{1, 3} ENSP00000273390⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
MYCBP	Q99417¹^,³, ENSP00000380702⁴	EBI-2119735,EBI-716185 I2D: score=3 STRING: ENSP00000380702
AKAP1	Q92667-2¹, ENSP00000337736⁴	EBI-2119735,EBI-2120060 I2D: score=1 STRING: ENSP00000337736
MYC	P01106³, ENSP00000367207⁴	I2D: score=1 STRING: ENSP00000367207
PRKAR2B	P31323³, ENSP00000265717⁴	I2D: score=1 STRING: ENSP00000265717

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0008295	spermidine biosynthetic process	--	--

MAATS1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, IUPHAR, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for MAATS1 (MAAT1)

Search CenterWatch for drugs/clinical trials and news about MAATS1 / MAAT1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for MAATS1 gene:

NM_033364.3

Unigene Cluster for MAATS1:

MYCBP-associated, testis expressed 1

Hs.341906 [show with all ESTs]

Unigene Representative Sequence: NM_033364

16 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000468630(uc010hqy.2) ENST00000273390(uc003ede.4 uc011bje.2)

ENST00000482573(uc010hqz.3 uc011bjd.2 uc003edg.4 uc003edh.4)

ENST00000463700(uc003edc.2) ENST00000482927 ENST00000488533 ENST00000469659(uc010hqx.1)

ENST00000475093 ENST00000483134(uc010hra.2) ENST00000498167 ENST00000461322

ENST00000470948 ENST00000482995 ENST00000472117 ENST00000496010 ENST00000475543

miRNA Products:
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat MAATS1
		Search QIAGEN for miScript miRNA Assays for microRNAs that regulate MAATS1
		SwitchGear 3'UTR luciferase reporter plasmid: MAATS1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene RNAi products in human, mouse, rat for MAATS1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MAATS1
		Sirion Biotech Custom design and validation of potent shRNA sequences against MAATS1

Clone Products:		OriGene clones in human, mouse for MAATS1 (see all 7) OriGene ORF clones in mouse, rat for MAATS1 OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript Custom all cDNA clones Services for MAATS1
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for MAATS1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAATS1

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for MAATS1
		Search SABiosciences RT² qPCR Primer Assays in human, mouse, rat MAATS1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAATS1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAATS1

Additional mRNA sequence:

AB063296.1 AB063297.1 AB063298.1 AF440403.1 AF497717.1 AK055558.1 AK289914.1 AK294413.1

AK302699.1 AK303997.1 AK309317.1 AK311599.1 BC126394.1 BX647600.1 CR749242.1

9 DOTS entries:

DT.100743411 DT.102980 DT.202858 DT.99974028 DT.92417071 DT.95357480 DT.100008349 DT.100731571

DT.120862959

24/54 AceView cDNA sequences (see all 54):

AW072384 CA950011 W01352 AW139311 BF476019 CK430532 AA913367 AW105127

AL713141 AW189056 NM_033364 BU680335 AW263635 CD359794 AI635030 AW118110

N62817 AI126652 AI703327 AA725754 BX508434 AF497717 AW664020 CR749242

GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for MAATS1 (see all 8) About this scheme

ExUns:	1a	·	1b	^	2a	·	2b	^	3	^	4	^	5	^	6	^	7a	·	7b	^	8	^	9a	·	9b	^	10	^	11	^	12	^	13a	·	13b	^	14a	·	14b	^	15	^	16	^	17	^	18	^	19a	·	19b	·
SP1:					-										-				-																				-						-				-		-
SP2:					-										-				-						-		-		-		-		-						-						-				-		-
SP3:					-										-				-
SP4:																			-
SP5:					-										-

ExUns:	19c	^	20	^	21a	·	21b	·	21c	·	21d
SP1:	-
SP2:	-
SP3:
SP4:
SP5:

ECgene alternative splicing isoforms for MAATS1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

MAATS1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>^2/3
CGAP TAG: --

About this image

See MAATS1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for MAATS1

SOURCE GeneReport for Unigene cluster: Hs.341906

UniProtKB/Swiss-Prot: MAAT1_HUMAN, Q7Z4T9

Tissue specificity: Isoform 1 is strongly expressed in the liver. Isoform 4 is widely expressed, but strongly expressed

in all spermatogenesis-related tissues, including the testis, the epithelium of cauda and the corpus epididymis, as

well as the spermatid and mature sperm. Isoform 4 is also expressed in Leydig cells. Isoform 3 is expressed in the

testis

SABiosciences Custom PCR Arrays for MAATS1

Primer Products:		OriGene qSTAR qPCR primer pairs in human, mouse for MAATS1
		Search SABiosciences RT² qPCR Primer Assays in human, mouse, rat MAATS1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAATS1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAATS1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAATS1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for MAATS1 gene from 5/12 species (see all 12) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
mouse (Mus musculus)	Mammalia	Maats1⁵ Spata26¹	RIKEN cDNA 4932425I24 gene⁵ spermatogenesis associated 26¹	80.53(n)¹ 76.74(a)¹		16 (26.71 cM)⁵ 320214¹ NM_001081025.1¹ NP_001074494.1¹ 38297754⁵
chicken (Gallus gallus)	Aves	C1H3orf15¹	chromosome 1 open reading frame, human C3orf15	68.96(n) 63.43(a)		427953 XM_425525.3 XP_425525.3
lizard (Anolis carolinensis)	Reptilia	C3ORF15⁶	Uncharacterized protein	59(a)	1 ↔ 1	GL343414.1(211192-272654)
zebrafish (Danio rerio)	Actinopterygii	BQ419805.1²	--	74.15(n)		BQ419805.1
fruit fly (Drosophila melanogaster)	Insecta	CG15145⁶ CG15144⁶ (see all 3)	--	14(a) 12(a) (see all 3)	many → 1 many → 1 (see all 3)	2L(17529311-17532234) 2L(17525585-17529070)

ENSEMBL Gene Tree for MAATS1 (if available)
TreeFam Gene Tree for MAATS1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for MAATS1 gene

1 SIMAP similar gene for MAATS1 using alignment to 5 protein entries: MAAT1_HUMAN (see all proteins):

C3orf15

MAATS1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, ⁴UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 3 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
VAR_030243⁴		--	--	see VAR_030243	2	A P	mis⁴		0	--	--	--	--
rs200333709^1,2	C	--	119419914(+)	`CAGATC/TGACCC`	1	--	us2k¹		0	--	--	--	--
rs114781288^1,2	C,F	--	119420013(+)	`TTACCA/GGTGCA`	1	--	us2k¹		2		WA NA	238
rs116649244^1,2	F	--	119420019(+)	`GTGCAT/CGCAGC`	1	--	us2k¹		1		WA	118
rs151146884^1,2		--	119420024(+)	`TGCAGC/GTCCCA`	1	--	us2k¹		0	--	--	--	--
rs114626214^1,2	C,F	--	119420073(+)	`CTCACG/ACAGAC`	1	--	us2k¹		1		NA	120
rs140125688^1,2		--	119420082(+)	`ACCCTC/GTTAGA`	1	--	us2k¹		0	--	--	--	--
rs181434758^1,2		--	119420089(+)	`TAGAGC/TTGTAT`	1	--	us2k¹		0	--	--	--	--
rs186177269^1,2		--	119420122(+)	`GCTCAC/TTCCGG`	1	--	us2k¹		0	--	--	--	--
rs73192040^1,2	C,F	--	119420209(+)	`TGAGCG/AGTTCT`	1	--	us2k¹		5		NA CSA WA	243

HapMap Linkage Disequilibrium report for MAATS1 (119421869 - 119485949 bp)

Structural Variations
Database of Genomic Variants (DGV) variations for MAATS1: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MAATS1

DNA2.0 Custom Variant and Variant Library Synthesis for MAATS1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

MAATS1 for disorders           About GeneDecksing

OMIM gene information: 609910    OMIM disorders: --

2 diseases for MAATS1:    About MalaCards

atherosclerosis

Export disorders for MAATS1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for MAATS1 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with MAATS1)

Utopia: connect your pdf to the dynamic
world of online information

AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex between AMY-1, A-kinase anchor protein 84 and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase. (PubMed id 12223483)^{1, 2, 3, 9} Yukitake H.... Ariga H. (2002)
Structure and characterization of AAT-1 isoforms. (PubMed id 15863901)^{1, 2, 9} Matsuda E.... Ariga H. (2005)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
Are polymorphic markers within the alpha-1-antitrypsin gene associated with risk of human immunodeficiency virus disease? (PubMed id 14551891)^{1, 3} Hayes V.M. and Gardiner-Garden M. (2003)
Protein interaction discovery using parallel analysis of translated ORFs (PLATO). (PubMed id 23503679)¹ Zhu J....Elledge S.J. (2013)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)² Muzny D.M....Gibbs R.A. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
Progression of atherosclerosis is associated with variation in the alpha1-antitrypsin gene. (PubMed id 12692006)¹ Talmud P.J....Syvanne M. (2003)
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 89876	HGNC: 24010	AceView: C3orf15	Ensembl:ENSG00000183833	euGenes: HUgn89876
ECgene: MAATS1	H-InvDB: MAATS1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for MAATS1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for MAATS1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for MAATS1 gene:
Search GeneIP for patents involving MAATS1

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section


	EMD Millipore Custom Antibody & Bulk Services
	EMD Millipore Preclinical / Clinical Development Services
	EMD Millipore Immunoassay Services
	EMD Millipore Target Screening & Profiling Services

	Browse Antibodies		Browse Cell Culture Products
	Browse ELISAs		Browse Flow Cytometry Kits
	Browse Primer Pairs		Browse Kinase Activity Assays/Reagents
	Browse ELISpot Kits/Development Modules		Browse TFB/Immunoprecipitation Assays
	Browse Apoptosis Detection Kits/Reagents		Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents
	Browse DNA Damage/Repair Kits/Reagents		Browse Multiplex/Array Assay Kits/Reagents
	Browse Cell Selection/Detection Kits/Reagents		Browse Secondary Antibodies/Controls/Staining Reagents
	Browse Protease Activity Assays and Reagents		Browse Recombinant/Natural Proteins
	Browse Stem Cell Products		Browse Tocris Biochemicals & Compounds
	Browse cDNA Clones		Browse Proteome Profiler Antibody Arrays

	Browse OriGene Antibodies		OriGene RNAi products in human, mouse, rat for MAATS1
	Browse OriGene qPCR primer pairs and template standards		OriGene Protein Over-expression Lysate for MAATS1
	OriGene MassSpec something-or-other for MAATS1		OriGene clones in human, mouse for MAATS1
	OriGene qSTAR qPCR primer pairs in human, mouse for MAATS1		OriGene Purified Protein for MAATS1
	OriGene ORF clones in mouse, rat for MAATS1		OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
	OriGene Custom Antibody Services for MAATS1		OriGene Custom Protein Services for MAATS1

	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat MAATS1
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing MAATS1
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat MAATS1
	QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat MAATS1
	QIAGEN QuantiFast Probe-based Assays in human, mouse, rat MAATS1
	QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat MAATS1

	GenScript Custom Purified and Recombinant Proteins Services for MAATS1		GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for MAATS1
	GenScript Custom Assay Services for MAATS1		GenScript Custom Superior Antibodies Services for MAATS1
	GenScript Custom overexpressing Cell Line Services for MAATS1		CloneReady with Over 120,000 Genes
	Gene Synthesis: Any Gene in Any Vector		Vector-based siRNA and miRNA, Ready for Transfection
	Gene Mutant Library, Variants up to 10^11		Plasmid Preparation
	Custom Peptide Services

Search for Antibodies & Assays

	Search Regulatory tfbs for MAATS1
	Search Chromatin IP Primers for MAATS1
	Search RT² qPCR Primer Assays in human, mouse, rat MAATS1
	Search GNC Networks for MAATS1
	SABiosciences Custom PCR Arrays for MAATS1

Search Tocris compounds for MAATS1 (MAAT1)

	Browse Sino Biological Proteins and Antibodies
	Browse Sino Biological Cell Lysates
	Browse Sino Biological cDNA Clones
	4000+ Proteins
	Search Sino Biological for antibodies, proteins & pathways
	Protein Production Services
	Transfection Reagents
	Protein A/G/L resins
	Isotyping reagents

Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

	Novus Tissue Slides
	MAATS1 antibodies
	MAATS1 proteins
	MAATS1 lysates

	Antibodies for MAATS1
	See all of Abcam's Antibodies, Kits and Proteins for MAATS1
	Custom Antibody / Protein Production Service
	Bulk Purchasing
	Advantages of Rabbit Monoclonal antibodies
	Abcam protocols and scientific support

Browse ProSpec Recombinant Proteins

	Browse Proteins at Cloud-Clone Corp.
	Browse Antibodies at Cloud-Clone Corp.
	Browse ELISAs at Cloud-Clone Corp.
	Browse CLIAs at Cloud-Clone Corp.

Search LifeMap BioReagents cell lines for MAATS1

	Gene Synthesis
	Protein Engineering
	Variant Library Synthesis
	Codon Optimization
	Protein Production and Purification

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAATS1

	SwitchGear 3'UTR luciferase reporter plasmids for MAATS1
	Browse SwitchGear Promoter luciferase reporter plasmids for MAATS1

ThermoFisher Antibodies for MAATS1

Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAATS1

	inGenious Targeting Laboratory - Custom generated mouse model solutions for MAATS1
	inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for MAATS1

Customized:

	stable knockdown cell line services for MAATS1
	inducible knockdown cell line services for MAATS1
	design and validation of potent shRNA sequences against MAATS1
	adenovirus for potent knockdown of MAATS1
	stable overexpressing cell line services for MAATS1
	inducible overexpressing cell line services for MAATS1
	adenovirus for overexpression of MAATS1

LSBio Antibodies in human, mouse, rat for MAATS1

GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013

View Random Gene

Category			TGFB1 (GIFtS: 73) transforming growth factor, beta 1
GIFtS Group

The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes MAATS1 gene at Home site.

hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4

Advanced Search

Export list of displayed genes

MAATS1 Gene

MYCBP-Associated, Testis Expressed 1

Aliases
for MAATS1 gene

Summaries
for MAATS1 gene

Genomic Views
for MAATS1 gene

Proteins
for MAATS1 gene

Protein Domains /
Families
for MAATS1 gene

Function
for MAATS1 gene

Pathways & Interactions
for MAATS1 gene

Drugs & Compounds
for MAATS1 gene

Transcripts
for MAATS1 gene

Expression
for MAATS1 gene

Orthologs
for MAATS1 gene

Paralogs
for MAATS1 gene

Genomic Variants
for MAATS1 gene

Disorders / Diseases
for MAATS1 gene

Publications
for MAATS1 gene

External Searches for MAATS1 gene

Genome Databases showing MAATS1 gene

Other Databases showing MAATS1 gene

Specialized Databases showing MAATS1 gene

Intellectual Property
for MAATS1 gene

Products
for MAATS1 gene

View Random Gene

Advanced Search

Export list of displayed genes

MAATS1 Gene

MYCBP-Associated, Testis Expressed 1

Aliasesfor MAATS1 gene

Summariesfor MAATS1 gene

Genomic Viewsfor MAATS1 gene

Proteinsfor MAATS1 gene

Protein Domains /Familiesfor MAATS1 gene

Functionfor MAATS1 gene

Pathways & Interactionsfor MAATS1 gene

Drugs & Compoundsfor MAATS1 gene

Transcriptsfor MAATS1 gene

Expression for MAATS1 gene

Orthologsfor MAATS1 gene

Paralogsfor MAATS1 gene

Genomic Variantsfor MAATS1 gene

Disorders / Diseasesfor MAATS1 gene

Publicationsfor MAATS1 gene

External Searches for MAATS1 gene

Genome Databases showing MAATS1 gene

Other Databases showing MAATS1 gene

Specialized Databases showing MAATS1 gene

Intellectual Propertyfor MAATS1 gene

Productsfor MAATS1 gene

View Random Gene

Aliases
for MAATS1 gene

Summaries
for MAATS1 gene

Genomic Views
for MAATS1 gene

Proteins
for MAATS1 gene

Protein Domains /
Families
for MAATS1 gene

Function
for MAATS1 gene

Pathways & Interactions
for MAATS1 gene

Drugs & Compounds
for MAATS1 gene

Transcripts
for MAATS1 gene

Expression
for MAATS1 gene

Orthologs
for MAATS1 gene

Paralogs
for MAATS1 gene

Genomic Variants
for MAATS1 gene

Disorders / Diseases
for MAATS1 gene

Publications
for MAATS1 gene

Intellectual Property
for MAATS1 gene

Products
for MAATS1 gene