Aliases for MAATS1 Gene
Aliases for MAATS1 Gene
- MYCBP Associated And Testis Expressed 1 2 3 5
- AMY-1-Associating Protein Expressed In Testis 1 2 3 4
- MYCBP/AMY-1-Associated Testis-Expressed Protein 1 3 4
- MYCBP/AMY-1-Associated, Testis Expressed 1 2 3
- MYCBP-Associated, Testis Expressed 1 2 3
- Spermatogenesis Associated 26 2 3
- MYCBP-Binding Protein 2 3
- Protein MAATS1 3 4
- C3orf15 3 4
- CFAP91 3 4
External Ids for MAATS1 Gene
- HGNC: 24010
- Entrez Gene: 89876
- Ensembl: ENSG00000183833
- OMIM: 609910
- UniProtKB: Q7Z4T9
Previous HGNC Symbols for MAATS1 Gene
- C3orf15
Previous GeneCards Identifiers for MAATS1 Gene
- GC03P119422
Summaries for MAATS1 Gene
GeneCards Summary for MAATS1 Gene
MAATS1 (MYCBP Associated And Testis Expressed 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include adenosylmethionine decarboxylase activity.
UniProtKB/Swiss-Prot for MAATS1 Gene
-
May regulate cilium motility through its role in the assembly of the axonemal radial spokes.
-
Isoform 4: May play a role in spermatogenesis.
Additional gene information for MAATS1 Gene
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MAATS1 Gene
Genomics for MAATS1 Gene
GeneHancer (GH) Regulatory Elements for MAATS1 Gene
Regulatory Element Products
Genomic Locations for MAATS1 Gene
- chr3:119,703,022-119,767,102
- (GRCh38/hg38)
- Size:
- 64,081 bases
- Orientation:
- Plus strand
- chr3:119,421,869-119,485,949
- (GRCh37/hg19)
Genomic View for MAATS1 Gene
- Cytogenetic band:
-
- 3q13.33 by Ensembl
- 3q13.33 by Entrez Gene
- 3q13.33 by HGNC


RefSeq DNA sequence for MAATS1 Gene
Proteins for MAATS1 Gene
-
Protein details for MAATS1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q7Z4T9-CFA91_HUMAN
- Recommended name:
- Cilia- and flagella-associated protein 91
- Protein Accession:
- Q7Z4T9
- A0AVK2
- A8K1J9
- B3KP23
- B4DG52
- B4DZ14
- C9JUG4
- Q68DX2
- Q8TD41
- Q96A45
- Q96JE8
Protein attributes for MAATS1 Gene
- Size:
- 603 amino acids
- Molecular mass:
- 70999 Da
- Quaternary structure:
-
- Interacts with MYCBP and AKAP1. Isoform 4 is part of a complex containing MYCBP, AKAP1 and PRKAR2B. Isoform 3 does not interact with MYCBP.
Protein Expression for MAATS1 Gene
Post-translational modifications for MAATS1 Gene
- Isoform 4 is phosphorylated by PKA.
Other Protein References for MAATS1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for MAATS1
- Invitrogen Antibodies for MAATS1
- Search GeneTex for Antibodies for MAATS1
Protein Products
-
OriGene Purified Proteins for MAATS1
- Search Origene for MassSpec and Protein Over-expression Lysates for MAATS1
- Origene Custom Protein Services for MAATS1
- antibodies-online: Search results for 4 available C3orf15 Proteins ranked by validation data
- Compare Top C3orf15 Proteins
-
Quality Products:
- Search GeneTex for Proteins for MAATS1
-
Abcam proteins for MAATS1
Assay Products
No data available for DME Specific Peptides for MAATS1 Gene
Domains & Families for MAATS1 Gene
Gene Families for MAATS1 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Protein Domains for MAATS1 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for MAATS1 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for MAATS1 Gene
Function for MAATS1 Gene
Molecular function for MAATS1 Gene
- UniProtKB/Swiss-Prot Function:
- May regulate cilium motility through its role in the assembly of the axonemal radial spokes.
- UniProtKB/Swiss-Prot Function:
- Isoform 4: May play a role in spermatogenesis.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 12223483 |
Phenotypes for MAATS1 Gene
- GenomeRNAi human phenotypes for MAATS1:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MAATS1
-
-
ViGene Biosciences lentiviral particle packaged cDNA for MAATS1 gene
-
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CRISPR Products
-
OriGene CRISPR knockouts for MAATS1
- genomics-online: gRNA clones - Search results for available C3orf15 gene related products
- Applied Biological Materials CRISPR for MAATS1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MAATS1
- GenScript: Design CRISPR guide RNA sequences for MAATS1
miRNA for MAATS1 Gene
- miRTarBase miRNAs that target MAATS1
miRNA Products
- Search ViGene Biosciences for MAATS1
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MAATS1
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- genomics-online: shRNA clones - Search results for available C3orf15 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for MAATS1 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for MAATS1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MAATS1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available C3orf15 gene related products
- orf clones - Search results for available C3orf15 gene related products
- Applied Biological Materials Clones for MAATS1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for MAATS1
-
ViGene Biosciences adenoviral particle packaged cDNA for MAATS1 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for MAATS1 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for MAATS1 gene
No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for MAATS1 Gene
Localization for MAATS1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for MAATS1 Gene
- Cytoplasm. Mitochondrion. Cytoplasm, cytoskeleton, cilium axoneme.
- Isoform 4: Mitochondrion. Note=Localized in the neck of the sperm. {ECO:0000269 PubMed:12223483}.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0001536 | colocalizes_with radial spoke stalk | ISS | -- |
GO:0005737 | cytoplasm | IEA | -- |
GO:0005739 | mitochondrion | IEA | -- |
GO:0005856 | cytoskeleton | IEA | -- |
GO:0005930 | axoneme | ISS | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for MAATS1 Gene
Pathways & Interactions for MAATS1 Gene
Interacting Proteins for MAATS1 Gene
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0003341 | cilium movement | ISS | -- |
No data available for Pathways by source and SIGNOR curated interactions for MAATS1 Gene
Transcripts for MAATS1 Gene
mRNA/cDNA for MAATS1 Gene
- (5) REFSEQ mRNAs :
- (15) Additional mRNA sequences :
- (54) Selected AceView cDNA sequences:
- (16) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for MAATS1 Gene
CRISPR Products
-
OriGene CRISPR knockouts for MAATS1
- genomics-online: gRNA clones - Search results for available C3orf15 gene related products
- Applied Biological Materials CRISPR for MAATS1
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MAATS1
- GenScript: Design CRISPR guide RNA sequences for MAATS1
miRNA Products
- Search ViGene Biosciences for MAATS1
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MAATS1
- Browse OriGene Inhibitory RNA Products For MAATS1
- genomics-online: shRNA clones - Search results for available C3orf15 gene related products
-
ViGene Biosciences ready-to-package AAV shRNAs for MAATS1 gene
Clone Products
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- VectorBuilder custom plasmid, inducible vectors for MAATS1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MAATS1
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- genomics-online: cdna clones - Search results for available C3orf15 gene related products
- orf clones - Search results for available C3orf15 gene related products
- Applied Biological Materials Clones for MAATS1
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
ExUns: | 1a | · | 1b | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13a | · | 13b | ^ | 14a | · | 14b | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19a | · | 19b | · |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||
SP2: | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
SP3: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
SP4: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
SP5: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
SP6: | - | - | ||||||||||||||||||||||||||||||||||||||||||||||||||
SP7: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
SP8: |
ExUns: | 19c | ^ | 20 | ^ | 21a | · | 21b | · | 21c | · | 21d |
---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | ||||||||||
SP2: | - | ||||||||||
SP3: | |||||||||||
SP4: | |||||||||||
SP5: | |||||||||||
SP6: | - | ||||||||||
SP7: | - | ||||||||||
SP8: |
Expression for MAATS1 Gene
mRNA differential expression in normal tissues according to GTEx for MAATS1 Gene
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for MAATS1 Gene
NURSA nuclear receptor signaling pathways regulating expression of MAATS1 Gene:
MAATS1SOURCE GeneReport for Unigene cluster for MAATS1 Gene:
Hs.341906mRNA Expression by UniProt/SwissProt for MAATS1 Gene:
Q7Z4T9-CFA91_HUMANEvidence on tissue expression from TISSUES for MAATS1 Gene
- Lung(4.1)
- Nervous system(4.1)
Primer Products
-
OriGene qPCR primer pairs for MAATS1
- genomics-online: primer clones - Search results for available C3orf15 gene related products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and Phenotype-based relationships between genes and organs from Gene ORGANizer for MAATS1 Gene
Orthologs for MAATS1 Gene
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
chimpanzee (Pan troglodytes) |
Mammalia | MAATS1 33 34 |
|
||
dog (Canis familiaris) |
Mammalia | NR1I2 33 |
|
||
MAATS1 34 |
|
OneToOne | |||
cow (Bos Taurus) |
Mammalia | MAATS1 33 34 |
|
||
mouse (Mus musculus) |
Mammalia | Maats1 33 16 34 |
|
||
rat (Rattus norvegicus) |
Mammalia | Maats1 33 |
|
||
oppossum (Monodelphis domestica) |
Mammalia | MAATS1 34 |
|
OneToOne | |
platypus (Ornithorhynchus anatinus) |
Mammalia | MAATS1 34 |
|
OneToOne | |
chicken (Gallus gallus) |
Aves | C1H3ORF15 33 |
|
||
MAATS1 34 |
|
OneToOne | |||
lizard (Anolis carolinensis) |
Reptilia | MAATS1 34 |
|
OneToOne | |
tropical clawed frog (Silurana tropicalis) |
Amphibia | maats1 33 |
|
||
zebrafish (Danio rerio) |
Actinopterygii | si:dkey-265i7.2 33 |
|
||
MAATS1 34 |
|
OneToOne | |||
fruit fly (Drosophila melanogaster) |
Insecta | CG15145 34 |
|
OneToMany | |
CG15144 34 |
|
OneToMany | |||
CG15143 34 |
|
OneToMany | |||
sea squirt (Ciona savignyi) |
Ascidiacea | -- 34 |
|
OneToOne |
- Species where no ortholog for MAATS1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for MAATS1 Gene
(1) SIMAP similar genes for MAATS1 Gene using alignment to 5 proteins:
No data available for Paralogs for MAATS1 Gene
Variants for MAATS1 Gene
SNP ID | Clin | Chr 03 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs1000029982 | -- | 119,738,964(+) | T/C | intron_variant | |
rs1000047424 | -- | 119,745,620(+) | A/G | intron_variant | |
rs1000052118 | -- | 119,761,511(+) | G/C | intron_variant | |
rs1000058370 | -- | 119,736,481(+) | T/C | intron_variant | |
rs1000105916 | -- | 119,719,942(+) | A/C | intron_variant |
Additional Variant Information for MAATS1 Gene
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MAATS1 Gene
Disorders for MAATS1 Gene
Additional Disease Information for MAATS1
No disorders were found for MAATS1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MAATS1 Gene
Publications for MAATS1 Gene
- AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex with AMY-1, A-kinase anchor protein 84, and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase. (PMID: 12223483) Yukitake H … Ariga H (The Journal of biological chemistry 2002) 2 3 4 22 58
- Structure and characterization of AAT-1 isoforms. (PMID: 15863901) Matsuda E … Ariga H (Biological & pharmaceutical bulletin 2005) 3 4 22 58
- A conserved CaM- and radial spoke associated complex mediates regulation of flagellar dynein activity. (PMID: 17967944) Dymek EE … Smith EF (The Journal of cell biology 2007) 2 3 58
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- Are polymorphic markers within the alpha-1-antitrypsin gene associated with risk of human immunodeficiency virus disease? (PMID: 14551891) Hayes VM … Gardiner-Garden M (The Journal of infectious diseases 2003) 2 3 58
Products for MAATS1 Gene
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- Invitrogen Antibodies for MAATS1
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Cyagen custom Knockout/knockin (KOKI) mouse models for MAATS1
- VectorBuilder custom plasmid, inducible vectors for MAATS1
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for MAATS1
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for 12 available C3orf15 Antibodies ranked by validation data
- Compare Top C3orf15 Antibodies
- Quality Products:
- antibodies-online: Search results for available C3orf15 related products ranked by validation data
- antibodies-online: Search results for 4 available C3orf15 Proteins ranked by validation data
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- Search GeneTex for Antibodies for MAATS1
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- genomics-online: cdna clones - Search results for available C3orf15 gene related products
- orf clones - Search results for available C3orf15 gene related products
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Sources for MAATS1 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
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- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew