Set Analyses:
GeneALaCart
GeneDecks
VarElect
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 


MAATS1 Gene

protein-coding   GIFtS: 42
GCID: GC03P119422

MYCBP-Associated, Testis Expressed 1

(Previous names: chromosome 3 open reading frame 15, MYCBP/AMY-1-associated,...)
(Previous symbol: C3orf15)
Pneumococci & Pneumococcal Diseases Congress
  See related disease
at
MalaCards
 

Aliases
for MAATS1 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus
Aliases
MYCBP-Associated, Testis Expressed 11 2     AAT-12 3
C3orf151 2 3 5     MYCBP/AMY-1-Associated Testis-Expressed Protein 12 3
AMY-1-Associating Protein Expressed In Testis 11 2 3     Chromosome 3 Open Reading Frame 151
AAT12 3 5     AAT1-alpha2
MYCBP/AMY-1-Associated, Testis Expressed 11 2     AAT1alpha2
MYCBP-Binding Protein1 2     SPATA262
Spermatogenesis Associated 261 2     Protein MAATS12

External Ids:    HGNC: 240101   Entrez Gene: 898762   Ensembl: ENSG000001838337   OMIM: 6099105   UniProtKB: Q7Z4T93   

Export aliases for MAATS1 gene to outside databases


Summaries
for MAATS1 gene

(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus
GeneCards Summary for MAATS1 Gene:
MAATS1 (MYCBP-associated, testis expressed 1) is a protein-coding gene. Diseases associated with MAATS1 include atherosclerosis.

UniProtKB/Swiss-Prot: MAAT1_HUMAN, Q7Z4T9
Function: Isoform 4 may play a role in spermatogenesis

Gene Wiki entry for MAATS1 (C3orf15) Gene


Genomic Views
for MAATS1 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000003.12  NT_005612.17  NC_018914.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for MAATS1
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for MAATS1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MAATS1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3q12-q13.3   Ensembl cytogenetic band:  3q13.33   HGNC cytogenetic band: 3q12-q13.3

MAATS1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
MAATS1 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P119422:  view genomic region     (about GC identifiers)

Start:
 119,421,869 bp from pter      End:
 119,485,949 bp from pter
Size:
 64,081 bases      Orientation:
 plus strand

Proteins
for MAATS1 gene

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus
UniProtKB/Swiss-Prot: MAAT1_HUMAN, Q7Z4T9 (See protein sequence)
Recommended Name: Protein MAATS1  
Size: 603 amino acids; 70999 Da
Subunit: Interacts with MYCBP and AKAP1. Isoform 4 is part of a complex containing MYCBP, AKAP1 and PRKAR2B.
Isoform 3 does not interact with MYCBP
Secondary accessions: A0AVK2 A8K1J9 B3KP23 B4DG52 B4DZ14 C9JUG4 Q68DX2 Q8TD41 Q96A45 Q96JE8
Alternative promoter usage, Alternative splicing: 8 isoforms:  Q7Z4T9-1   Q7Z4T9-2   Q7Z4T9-3   Q7Z4T9-4   Q7Z4T9-6   Q7Z4T9-7   Q7Z4T9-8   Q7Z4T9-5   
(May be produced by alternative promoter usage)

Explore the universe of human proteins at neXtProt for MAATS1: NX_Q7Z4T9

Explore proteomics data for MAATS1 at MOPED

Post-translational modifications: 

  • Isoform 4 is phosphorylated by PKA1
  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

    • See MAATS1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_203528.2  
    ENSEMBL proteins: 
     ENSP00000273390   ENSP00000419520   ENSP00000419489   ENSP00000418601   ENSP00000419972  
     ENSP00000419554  

    MAATS1 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for MAATS1
    OriGene Protein Over-expression Lysate for MAATS1
    OriGene MassSpec for MAATS1
    OriGene Custom Protein Services for MAATS1
    GenScript Custom Purified and Recombinant Proteins Services for MAATS1
    Novus Biologicals MAATS1 Protein
    Novus Biologicals MAATS1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

    MAATS1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for MAATS1
    OriGene Custom Antibody Services for MAATS1
    Novus Biologicals MAATS1 Antibodies
    Search for Antibodies for MAATS1 at Abcam
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibodies for MAATS1
    LSBio Antibodies in human, mouse, rat for MAATS1

    MAATS1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for MAATS1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for MAATS1
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.

    Domains /
    Families
    for MAATS1 gene

    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus    		 1 InterPro protein domain:
     IPR026720 AAT1

    Graphical View of Domain Structure for InterPro Entry Q7Z4T9

    ProtoNet protein and cluster: Q7Z4T9


    MAATS1 for domains           About GeneDecksing


    Function
    for MAATS1 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus
    Molecular Function:

         UniProtKB/Swiss-Prot Summary: MAAT1_HUMAN, Q7Z4T9
    Function: Isoform 4 may play a role in spermatogenesis

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004014adenosylmethionine decarboxylase activity ----
    GO:0005515protein binding IPI12223483
         
    MAATS1 for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MAATS1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MAATS1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for MAATS1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for MAATS1

    miRNA
    Products:            		Block miRNA regulation of human, mouse, rat MAATS1 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate MAATS1
    SwitchGear 3'UTR luciferase reporter plasmid: MAATS1 3' UTR sequence
    Inhib. RNA
    Products:            		OriGene RNAi products in human, mouse, rat for MAATS1
    Predesigned siRNA for gene silencing in human, mouse, rat MAATS1

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for MAATS1

    Clone
    Products:             		 OriGene clones in human, mouse for MAATS1 (see all 7)
    OriGene ORF clones in mouse, rat for MAATS1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for MAATS1
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MAATS1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAATS1

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for MAATS1
    Browse ESI BIO Cell Lines and PureStem Progenitors for MAATS1 
    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAATS1


    Localization
    for MAATS1 gene

    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus
    Subcellular locations from UniProtKB/Swiss-Prot
    MAAT1_HUMAN, Q7Z4T9: Cytoplasm. Mitochondrion. Note=Isoform 4 is found in the mitochondria and localized in the
    neck of the sperm

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IEA--

    MAATS1 for ontologies           About GeneDecksing


    Pathways & Interactions
    for MAATS1 gene

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus


        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for MAATS1
    Interactions:

        Search GeneGlobe Interaction Network for MAATS1

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for MAATS1 (Q7Z4T91, 3 ENSP000002733904) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    MYCBPQ994171, 3, ENSP000003807024EBI-2119735,EBI-716185 I2D: score=3 STRING: ENSP00000380702
    AKAP1Q92667-21, ENSP000003377364EBI-2119735,EBI-2120060 I2D: score=1 STRING: ENSP00000337736
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    PRKAR2BP313233, ENSP000002657174I2D: score=1 STRING: ENSP00000265717
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008295spermidine biosynthetic process ----

    MAATS1 for ontologies           About GeneDecksing



    Drugs & Compounds
    for MAATS1 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for MAATS1 (MAAT1)



    Transcripts
    for MAATS1 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus
    REFSEQ mRNAs for MAATS1 gene: 
    NM_033364.3  

    Unigene Cluster for MAATS1:

    MYCBP-associated, testis expressed 1
    Hs.341906  [show with all ESTs]
    Unigene Representative Sequence: NM_033364
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000468630(uc010hqy.2) ENST00000273390(uc003ede.4 uc011bje.2)
    ENST00000482573(uc010hqz.3 uc011bjd.2 uc003edg.4 uc003edh.4)
    ENST00000463700(uc003edc.2) ENST00000482927 ENST00000488533 ENST00000469659(uc010hqx.1)
    ENST00000475093 ENST00000483134(uc010hra.2) ENST00000498167 ENST00000461322
    ENST00000470948 ENST00000482995 ENST00000472117 ENST00000496010 ENST00000475543


    miRNA
    Products:             		 Block miRNA regulation of human, mouse, rat MAATS1 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate MAATS1
    SwitchGear 3'UTR luciferase reporter plasmid: MAATS1 3' UTR sequence
    Inhib. RNA
    Products:             		OriGene RNAi products in human, mouse, rat for MAATS1
    Predesigned siRNA for gene silencing in human, mouse, rat MAATS1
    Clone
    Products:             		 OriGene clones in human, mouse for MAATS1 (see all 7)
    OriGene ORF clones in mouse, rat for MAATS1
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for MAATS1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for MAATS1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAATS1
    Primer
    Products:            		OriGene qSTAR qPCR primer pairs in human, mouse for MAATS1
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat MAATS1
      QuantiTect SYBR Green Assays in human, mouse, rat MAATS1
      QuantiFast Probe-based Assays in human, mouse, rat MAATS1

    Additional mRNA sequence: 

    AB063296.1 AB063297.1 AB063298.1 AF440403.1 AF497717.1 AK055558.1 AK289914.1 AK294413.1 
    AK302699.1 AK303997.1 AK309317.1 AK311599.1 BC126394.1 BX647600.1 CR749242.1 

    9 DOTS entries:

    DT.100743411  DT.102980  DT.202858  DT.99974028  DT.92417071  DT.95357480  DT.100008349  DT.100731571 
    DT.120862959 

    Selected AceView cDNA sequences (see all 54):

    AA913367 AW072384 AL713141 W01352 AW105127 BF476019 NM_033364 AW139311 
    CA950011 AW263635 CK430532 BU680335 AW189056 BX508434 CR749242 AI220489 
    AA969248 N62817 CD103392 BX647600 AI703327 AI635030 AF440403 AW118110 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for MAATS1 (see all 8)    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14a · 14b ^ 15 ^ 16 ^ 17 ^ 18 ^ 19a · 19b ·
    SP1:              -                             -           -                                                           -                 -           -     -   
    SP2:              -                             -           -                 -     -     -     -     -                 -                 -           -     -   
    SP3:              -                             -           -                                                                                                   
    SP4:                                                        -                                                                                                   
    SP5:              -                             -                                                                                                               

    ExUns: 19c ^ 20 ^ 21a · 21b · 21c · 21d
    SP1:  -                                 
    SP2:  -                                 
    SP3:                                    
    SP4:                                    
    SP5:                                    


    ECgene alternative splicing isoforms for MAATS1

    Expression
    for MAATS1 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    MAATS1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    MAATS1 Expression
    About this image

    MAATS1 Protein expression data from MOPED1, PaxDb2 and MaxQB3:     About this image

    MAATS1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.341906

    UniProtKB/Swiss-Prot: MAAT1_HUMAN, Q7Z4T9
    Tissue specificity: Isoform 1 is strongly expressed in the liver. Isoform 4 is widely expressed, but strongly
    expressed in all spermatogenesis-related tissues, including the testis, the epithelium of cauda and the corpus
    epididymis, as well as the spermatid and mature sperm. Isoform 4 is also expressed in Leydig cells. Isoform 3 is
    expressed in the testis

        Custom PCR Arrays for MAATS1
    Primer
    Products:    		OriGene qSTAR qPCR primer pairs in human, mouse for MAATS1
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat MAATS1
    QuantiTect SYBR Green Assays in human, mouse, rat MAATS1
    QuantiFast Probe-based Assays in human, mouse, rat MAATS1
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAATS1

    Orthologs
    for MAATS1 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus
    This gene was present in the common ancestor of animals.

    Orthologs for MAATS1 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Maats11 , 5 RIKEN cDNA 4932425I24 gene5
    MYCBP-associated, testis expressed 11    		 80.53(n)1
    76.74(a)1    		   16 (26.71 cM)5
    3202141  NM_001081025.11  NP_001074494.11 
     382977545 
    chicken
    (Gallus gallus)    		 Aves C1H3ORF151 chromosome 1 open reading frame, human C3orf15 69.03(n)
    63.5(a)    		   427953  XM_425525.4  XP_425525.4 
    lizard
    (Anolis carolinensis)    		 Reptilia MAATS16
    		 MYCBP-associated, testis expressed 1
    		 60(a)
    		 1 ↔ 1
    		 GL343414.1(211192-272654)
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia maats11 MYCBP-associated, testis expressed 1 64.6(n)
    62.25(a)    		   100151718  NM_001127421.1  NP_001120893.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii BQ419805.12   -- 74.15(n)    BQ419805.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG151456
    CG151446
    (see all 3)    		 --
    		 15(a)
    14(a)
    (see all 3)    		 many → 1
    many → 1
    (see all 3)    		 2L(17529311-17532234)
    2L(17525585-17529070)


    ENSEMBL Gene Tree for MAATS1 (if available)
    TreeFam Gene Tree for MAATS1 (if available)

    Paralogs
    for MAATS1 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for MAATS1 gene
    1 SIMAP similar gene for MAATS1 using alignment to 5 protein entries:     MAAT1_HUMAN (see all proteins):
    C3orf15

    MAATS1 for paralogs           About GeneDecksing



    Genomic Variants
    for MAATS1 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus
    Selected SNPs for MAATS1 (see all 1302)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 3 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs2003337091,2
    		C--119419914(+) CAGATC/TGACCC 1 -- us2k10--------
    rs1147812881,2
    		C,F--119420013(+) TTACCA/GGTGCA 1 -- us2k12Minor allele frequency- G:0.03WA NA 238
    rs1166492441,2
    		F--119420019(+) GTGCAT/CGCAGC 1 -- us2k11Minor allele frequency- C:0.03WA 118
    rs1511468841,2
    		--119420024(+) TGCAGC/GTCCCA 1 -- us2k10--------
    rs1146262141,2
    		C,F--119420073(+) CTCACG/ACAGAC 1 -- us2k11Minor allele frequency- A:0.02NA 120
    rs1401256881,2
    		--119420082(+) ACCCTC/GTTAGA 1 -- us2k10--------
    rs1814347581,2
    		--119420089(+) TAGAGC/TTGTAT 1 -- us2k10--------
    rs1861772691,2
    		--119420122(+) GCTCAC/TTCCGG 1 -- us2k10--------
    rs731920401,2
    		C,F--119420209(+) TGAGCG/AGTTCT 1 -- us2k15Minor allele frequency- A:0.08NA CSA WA 243
    rs1131893941,2
    		C--119420394(+) TTCCCT/-TTACT 1 -- us2k11Minor allele frequency- -:0.50CSA 2

    HapMap Linkage Disequilibrium report for MAATS1 (119421869 - 119485949 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for MAATS1: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing MAATS1
    DNA2.0 Custom Variant and Variant Library Synthesis for MAATS1

    Disorders / Diseases
    for MAATS1 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus    		 OMIM gene information: 609910    OMIM disorders: --

    1 disease for MAATS1:    About MalaCards
    atherosclerosis


    MAATS1 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    The International Symposium on Pneumococci and Pneumococcal Diseases (ISPPD) 9 - 13 March 2014

    Export disorders for MAATS1 gene to outside databases

    Publications
    for MAATS1 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus
    PubMed articles for MAATS1 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with MAATS1)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. AAT-1, a novel testis-specific AMY-1-binding protein, forms a quaternary complex between AMY-1, A-kinase anchor protein 84 and a regulatory subunit of cAMP-dependent protein kinase and is phosphorylated by its kinase. (PubMed id 12223483)1, 2, 3, 9 Yukitake H.... Ariga H. (J. Biol. Chem. 2002)
    2. Structure and characterization of AAT-1 isoforms. (PubMed id 15863901)1, 2, 9 Matsuda E.... Ariga H. (Biol. Pharm. Bull. 2005)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    4. Are polymorphic markers within the alpha-1-antitrypsin gene associated with risk of human immunodeficiency virus disease? (PubMed id 14551891)1, 3 Hayes V.M. and Gardiner-Garden M. (J. Infect. Dis. 2003)
    5. Protein interaction discovery using parallel analysis of translated ORFs (PLATO). (PubMed id 23503679)1 Zhu J....Elledge S.J. (Nat. Biotechnol. 2013)
    6. The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (BMC Genomics 2007)
    7. The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)2 Muzny D.M....Gibbs R.A. (Nature 2006)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    9. Progression of atherosclerosis is associated with variation in the alpha1-antitrypsin gene. (PubMed id 12692006)1 Talmud P.J....SyvAonne M. (Arterioscler. Thromb. Vasc. Biol. 2003)
    10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

    External Searches for MAATS1 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing MAATS1 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 89876 HGNC: 24010 AceView: C3orf15 Ensembl:ENSG00000183833 euGenes: HUgn89876
    ECgene: MAATS1 H-InvDB: MAATS1

    Other Databases showing MAATS1 gene

    (According to HUGE)
    About This Section

    TryGeneCards Plus    		   --

    Specialized Databases showing MAATS1 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for MAATS1 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for MAATS1 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus    		Patent Information for MAATS1 gene:
    Search GeneIP for patents involving MAATS1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for MAATS1 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus
     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for MAATS1   OriGene RNAi products in human, mouse, rat for MAATS1  
     Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for MAATS1  
     OriGene MassSpec something-or-other for MAATS1   OriGene clones in human, mouse for MAATS1  
     OriGene qSTAR qPCR primer pairs in human, mouse for MAATS1   OriGene Purified Protein for MAATS1  
     OriGene ORF clones in mouse, rat for MAATS1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for MAATS1   OriGene Custom Protein Services for MAATS1  

         		 
     Block miRNA regulation of human, mouse, rat MAATS1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing MAATS1
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat MAATS1 Predesigned siRNA for gene silencing in human, mouse, rat MAATS1
     QuantiFast Probe-based Assays in human, mouse, rat MAATS1 QuantiTect SYBR Green Assays in human, mouse, rat MAATS1
     Custom PCR Arrays for MAATS1 Search Chromatin IP Primers for MAATS1
     Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat MAATS1 Search GeneGlobe Interaction Network for MAATS1
     Search Regulatory tfbs for MAATS1
     GenScript Custom Purified and Recombinant Proteins Services for MAATS1 GenScript Custom cDNA clones with any tag delivered in your preferred vector Services for MAATS1
     GenScript Custom Assay Services for MAATS1 GenScript Custom overexpressing Cell Line Services for MAATS1
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for MAATS1 (MAAT1)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     MAATS1 antibodies
     MAATS1 proteins
     MAATS1 lysates
     Search for Antibodies for MAATS1 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for MAATS1
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Browse Proteins at Cloud-Clone Corp.
     Browse Antibodies at Cloud-Clone Corp.
     Browse ELISAs at Cloud-Clone Corp.
     Browse CLIAs at Cloud-Clone Corp.



     Browse ESI BIO Cell Lines and PureStem Progenitors for MAATS1
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for MAATS1
     SwitchGear 3'UTR luciferase reporter plasmids for MAATS1
     Browse SwitchGear Promoter luciferase reporter plasmids for MAATS1
     ThermoFisher Antibodies for MAATS1
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat MAATS1
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for MAATS1
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for MAATS1
     LSBio Antibodies in human, mouse, rat for MAATS1
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Copyright © 1996-2014 , Weizmann Institute of Science. All Rights Reserved.
    Hot genes      Disease genes      MAATS1 gene at Home site.
    Version: 3.12.136 22 July 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4