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EPCAM Gene

protein-coding GIFtS: 56

GC02P047425

epithelial cell adhesion molecule
(Previous names: antigen identified by monoclonal antibody AUA1, tumor-associated calcium signal transducer 1 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbols: M4S1, MIC18, TACSTD1)

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
17-1A ^¹
323/A3 ^¹
CD326 ^¹
CO-17A ^¹, ²
CO17-1A ^²
EGP ^², ³
EGP-2 ^¹, ²
EGP34 ^¹, ²
EGP40 ^¹, ²
ESA ^¹, ²
Ep-CAM ^¹, ²
GA733-2 ^¹, ², ³
HEA125 ^¹
KS1/4 ^¹, ²
KSA ^¹, ², ³
Ly74 ^¹
M1S2 ^³
M4S1 ^², ³
MH99 ^¹
MIC18 ^², ³
MK-1 ^¹, ²
MOC31 ^¹
TACST-1 ^¹, ²
TACSTD1 ^²
TROP1 ^¹, ², ³
hEGP-2 ^²

Descriptions
Adenocarcinoma-associated antigen ^², ³
CD326 antigen ^³
Cell surface glycoprotein Trop-1 ^³
Epithelial cell surface antigen ^³
Epithelial glycoprotein ^³
KS 1/4 antigen ^³
Major gastrointestinal tumor-associated protein GA733-2 ^³
antigen identified by monoclonal antibody AUA1 ^¹
carcinoma-associated antigen GA733-2 ^²
epithelial cell adhesion molecule ^²
human epithelial glycoprotein-2 ^²
membrane component, chromosome 4, surface marker (35kD glycoprotein) ^²
tumor-associated calcium signal transducer 1 ^¹, ²

External Ids
HGNC: 11529¹
Entrez Gene: 4072²
UniProtKB: P16422³
Ensembl: ENSG00000119888⁷

Search outside databases for aliases for EPCAM gene

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for EPCAM:

This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least

two type I membrane proteins. This antigen is expressed on most normal epithelial cells and

gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion

molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas.

Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq]

UniProtKB/Swiss-Prot: TACD1_HUMAN, P16422

Function: GA733 tumor-associated antigen gene family may function as growth factor receptors

Gene Wiki entry for EPCAM (Tumor-associated_calcium_signal_transducer_1)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p21 Ensembl cytogenetic band: 2p21 HGNC cytogenetic band: 2p21

EPCAM Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 2 GeneLoc Exon Structure

GeneLoc location for GC02P047425: (about GC identifiers)

Start:	47,425,801 bp from pter
End:	47,467,661 bp from pter
Size:	41,861 bases
Orientation:	plus strand

RefSeq DNA sequence:

NC_000002.10 NT_022184.14

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: TACD1_HUMAN, P16422 (See protein sequence)

Recommended Name: Tumor-associated calcium signal transducer 1 precursor

Size: 314 amino acids; 34932 Da

Subunit: Monomer

Subcellular location: Membrane; Single-pass type I membrane protein

Secondary accessions: P18180 Q6FG26 Q6FG49 Q96C47 Q9UCD0

REFSEQ proteins: NP_002345.2

ENSEMBL proteins:

ENSP00000263735 ENSP00000385476

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	R&D Systems Recombinant & Natural Proteins for EPCAM (EpCAM/TROP-1)
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (EpCAM)
	Human Recombinant Proteins from Abnova (TACSTD1)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

2 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	TAS	1729376
GO:0016021	integral to membrane	IEA	--

About this table

Antibodies for EPCAM:

	Invitrogen Antibodies for EPCAM
	Millipore Mono- and Polyclonal Antibodies for the study of EPCAM
	Sigma-Aldrich Antibodies for EPCAM
	R&D Systems Antibodies for EPCAM (EpCAM/TROP-1)
	Cell Signaling Technology (CST) Antibodies for EPCAM
	Antibodies from Abcam (EpCAM), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (TACSTD1)
	Novus Biologicals Antibodies for EPCAM

Assays for EPCAM:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	R&D Systems ELISAs for EPCAM (EpCAM/TROP-1) (see all)
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P16422

ProtoNet protein and cluster: P16422

1 Blocks protein family: IPB000716 Thyroglobulin type-1

UniProtKB/Swiss-Prot: TACD1_HUMAN, P16422

Similarity: Contains 1 thyroglobulin type-1 domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (EPCAM)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002354

Applied Biosystems Silencer® siRNAs for EPCAM

Sigma-Aldrich siRNA and siRNA Panels for EPCAM

Sigma-Aldrich shRNA for EPCAM

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for EPCAM
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_002354
Myc/DDK tagged cDNA clone in CMV expression vector: NM_002354
untagged cDNA clones in CMV expression vector (see all 2): NM_002354

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_002354

UniProtKB/Swiss-Prot: TACD1_HUMAN, P16422

Function: GA733 tumor-associated antigen gene family may function as growth factor receptors

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Gene Network Central^TM Interacting Genes and Proteins Network for EPCAM

5/12 Interacting proteins for EPCAM (ENSP00000263735³) via UniProtKB, MINT, and/or STRING (see all 12 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
TP53	ENSP00000269305³	STRING (score=.85)
TCF7L2	ENSP00000344823³	STRING (score=.847)
CD79A	ENSP00000221972³	STRING (score=.842)
HLA-C	ENSP00000365402³	STRING (score=.814)
CDH1	ENSP00000268794³	STRING (score=.744)

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for EPCAM
4 Novoseek chemical compound relationships for EPCAM gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
adecatumumab	86.71	2	16937114 (1), 16102830 (1)
exotoxin-a	32.44	1	11093823 (1)
p003	0.00	1	17361206 (1)
thymidine	0.00	1	16034560 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (EPCAM)
		Browse for Gene Knock-down Tools from Millipore
		Browse Abnova for Chimera RNAi Products

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_002354

Sigma-Aldrich siRNA and siRNA Panels for EPCAM

Sigma-Aldrich shRNA for EPCAM

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_002354

REFSEQ mRNAs for EPCAM gene:

NM_002354.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_002354

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_002354
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_002354
                                 untagged cDNA clones in CMV expression vector (see all 2): NM_002354

Additional cDNA sequence:

AK026585.1 BC014785.1 CR542259.1 CR542283.1 CR593061.1 CR626162.1 M26481.1 M32306.1

M32325.1 M33011.1 X14758.1

13 DOTS entries:

DT.87014014 DT.218154 DT.100824777 DT.100824778 DT.95197888 DT.100824775 DT.91770051 DT.95306990

DT.91866556 DT.100807173 DT.87016265 DT.120994666 DT.40235087

24/435 AceView cDNA sequences (see all 435 ):

AA847578 CR593061 W32964 BQ778631 W39707 BM854437 AI951481 AI721217

CR542283 BE843159 CA942830 AL047838 BM751257 BQ778413 AI978632 AW167961

BM818348 AW168044 BM843988 BC014785 CB159310 CD108409 AA424668 AI264210

Unigene Cluster for EPCAM:

Epithelial cell adhesion molecule

Hs.542050 [show with all ESTs]

Unigene Representative Sequence: NM_002354

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for EPCAM

ExUns:	1	^	2a	·	2b	·	2c	^	3	^	4a	·	4b	·	4c	·	4d	^	5	^	6	^	7	^	8	^	9	^	10
SP1:							-				-
SP2:
SP3:			-		-		-				-
SP4:											-

About this scheme

ECgene alternative splicing isoforms for EPCAM

2 Ensembl transcripts including schematic representations:

ENST00000263735 ENST00000405271

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

EPCAM expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for EPCAM

¹ / ²

3 probe-sets matching EPCAM gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
575_s_at²	U95-A	1	1.00	1.00	1.00	1.00	--	--	--	--	--
201839_s_at²	U133-A	1	1.00	1.00	--	--	--	--	--	--	--
201839_s_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks EPCAM for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: AGTTTGTTAG

SOURCE GeneReport for Unigene cluster: Hs.542050
UniProtKB/Swiss-Prot: TACD1_HUMAN, P16422
Tissue specificity: This protein is expressed in almost all epithelial cell membranes but not on
mesodermal or neural cell membranes. Found on the surface of adenocarcinomas

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for EPCAM gene from 5/9 species (see all 9 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	EPCAM¹	--	epithelial cell adhesion molecule	87.5(n) 82.64(a)	481360 XM_538481.2 XP_538481.2
chimpanzee (Pan troglodytes)	EPCAM¹	--	epithelial cell adhesion molecule	98.97(n) 97.59(a)	459214 XM_515458.2 XP_515458.2
cow (Bos taurus)	EPCAM¹	--	epithelial cell adhesion molecule	86.94(n) 82.8(a)	514039 NM_001035290.1 NP_001030367.1
rat (Rattus norvegicus)	Tacstd1¹	--	tumor-associated calcium signal transducer 1	79.41(n) 82.17(a)	171577 NM_138541.1 NP_612550.1
mouse (Mus musculus)	Epcam^{1, 5}	17⁵	epithelial cell adhesion molecule^{1, 5}	79.62(n)¹ 81.85(a)¹	17075¹ NM_008532.2¹ NP_032558.2¹ AJ489452⁵ AJ489453⁵ (see all 15)

About this table Species with no ortholog for EPCAM

ENSEMBL Gene Tree for EPCAM

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for EPCAM gene

TACSTD2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/124 NCBI SNPs in EPCAM are shown (see all 124 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 30)

AB	SNP ID	Valid	Chr 2 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
	rs1126497^1,2	A,C,F,H,O	47454610(+)	`CTCCAC/TGTGCT`	1	T/M	mis¹		18		MN EU EA WA NA	1880
--	rs1421^1,2	A,C,F,H,O	47467374(-)	`CAAATA/GTATGA`	1	--	ut3¹		10		MN NA EU EA WA	1116
	rs3814359^1,2	C,F,H	47449628(-)	`TGAAGC/ACTTGA`	1	--	ng5¹		6		MN EA EU WA	774
	rs11554292^1,2	F,H	47467521(-)	`AATGTT/AACACA`	1	--	ut3¹ ese³		4		EU EA WA	418
	rs3203645^1,2	H	47467471(+)	`CAGATC/TTAATG`	1	--	ut3¹		5		MN EU EA WA	602
	rs13033384^1,2	C	47449606(+)	`CCTTCC/TCCCCA`	1	--	ng5¹ trp³		0	--	--	--	--
	rs1126913^1,2	H	47467553(+)	`CTTCCA/CCAGTA`	1	--	ut3¹ ese³		4		MN EU EA	476
	rs7584256^1,2	A,C,F,H	47465728(+)	`ATGTCC/TATTAA`	1	--	int¹		11		EU EA WA NA	980
	rs3923559^1,2	A,C,F,H	47460278(-)	`CTAATC/TTATTG`	1	--	int¹		8		EU EA WA	838
	rs3924917^1,2	A,C,F,H	47466382(+)	`TGTGTA/GTCTTT`	1	--	int¹		12		EU EA WA NA	1050

About this table

HapMap Linkage Disequilibrium images for EPCAM (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 185535

10/51 Novoseek disease relationships for EPCAM gene (see all 51 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
carcinoma	67.19	90	17586680 (5), 17683191 (4), 17600130 (3), 18508581 (2) (see all 55)
colorectal carcinoma	59.86	14	17361206 (3), 15570423 (2), 12673686 (1), 7539133 (1) (see all 9)
malignant ascites	59.44	3	19443405 (1), 17410361 (1), 17900673 (1)
tumors	59.31	139	17361206 (5), 11948467 (4), 15557427 (4), 17213811 (4) (see all 72)
cancer	52.02	70	16775119 (6), 17211480 (3), 17213811 (3), 17069841 (2) (see all 36)
gastrointestinal carcinoma	51.27	6	11080501 (1), 16034560 (1), 10811480 (1)
colon carcinoma	45.98	5	16971804 (1), 16404366 (1), 15637741 (1)
ovarian cancer	43.54	15	14581349 (5), 9873999 (1), 16678891 (1), 9139849 (1) (see all 9)
metastasis	42.96	22	9109790 (3), 11439361 (3), 9873999 (2), 18383834 (2) (see all 12)
adenocarcinoma	42.91	26	19443410 (6), 15569986 (2), 15637741 (2), 15955212 (2) (see all 16)

About this table

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/261 PubMed articles for EPCAM gene (see all 261 ):

Retroposition in a family of carcinoma-associated antigen genes. (PubMed id 8382772)^{1, 2, 3, 4} Linnenbach A.J.... Huebner K. (1993)
Determination of disulfide bond assignments and N-glycosylation sites of the human gastrointestinal carcinoma antigen GA733-2 (CO17-1A, EGP, KS1-4, KSA, and Ep-CAM). (PubMed id 11080501)^{1, 3, 4} Chong J.M. and Speicher D.W. (2001)
Epithelial glycoprotein is a member of a family of epithelial cell surface antigens homologous to nidogen, a matrix adhesion protein. (PubMed id 2108441)^{1, 3, 4} Simon B.... Brand S.J. (1990)
Molecular cloning of cDNA for the carcinoma-associated antigen GA733- 2. (PubMed id 2333300)^{1, 3, 4} Szala S.... Linnenbach A.J. (1990)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Assignment of TACSTD1 (alias TROP1, M4S1) to human chromosome 2p21 and refinement of mapping of TACSTD2 (alias TROP2, M1S1) to human chromosome 1p32 by in situ hybridization. (PubMed id 11306819)^{2, 3} Calabrese G....Alberti S. (2001)
Isolation, partial characterization, and molecular cloning of a human colon adenocarcinoma cell-surface glycoprotein recognized by the C215 mouse monoclonal antibody. (PubMed id 7693697)^{3, 4} Bjork P.... Kalland T. (1993)
Molecular cloning and characterization of a human adenocarcinoma/epithelial cell surface antigen complementary DNA. (PubMed id 2463074)^{3, 4} Strnad J.... Gadski R.A. (1989)
Sequence investigation of the major gastrointestinal tumor-associated antigen gene family, GA733. (PubMed id 2911574)^{3, 4} Linnenbach A.J.... Koprowski H. (1989)
Isolation and characterization of a cDNA encoding the KS1/4 epithelial carcinoma marker. (PubMed id 2469722)^{3, 4} Perez M.S. and Walker L.E. (1989)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 4072	HGNC: 11529	AceView: TACSTD1	Ensembl:ENSG00000119888	euGenes: HUgn4072
ECgene: EPCAM	H-InvDB: EPCAM

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
ATLAS Chromosomes in Cancer entry for EPCAM	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for EPCAM
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for EPCAM:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for EPCAM-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for EPCAM		Antibodies for EPCAM
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for EPCAM		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (TACSTD1)
	Antibodies (TACSTD1)
	Search for Chimera RNAi
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Antibodies & Assays for EPCAM

	Recombinant Proteins (EpCAM)
	Antibodies (EpCAM)

Search OriGene for EPCAM

Search Tocris compounds for EPCAM

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for EPCAM

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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EPCAM Gene at Home site.
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EPCAM Gene

protein-coding GIFtS: 56

Aliases &
Descriptions
for EPCAM

Summaries
for EPCAM

Genomic Location
for EPCAM

Proteins
for EPCAM

Protein Domains/
Families
for EPCAM

Gene Function
for EPCAM

Pathways & Interactions
for EPCAM

Drugs & Compounds
for EPCAM

Transcripts
for EPCAM

Expression
for EPCAM

Orthologs
for EPCAM

Paralogs
for EPCAM

SNPs/Variants
for EPCAM

Disorders & Mutations
for EPCAM

Medical News
for EPCAM

Publications
for EPCAM

Search for EPCAM

Genome Databases showing EPCAM

Other Databases showing EPCAM

Specialized Databases showing EPCAM

Licensable Technologies
for EPCAM

Services
for EPCAM

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

EPCAM (Gene Symbol)
17-1A
323/A3
CD326
CO-17A
CO17-1A
EGP
EGP-2
EGP34
EGP40
ESA
Ep-CAM
GA733-2
HEA125
KS1/4
KSA
Ly74
M1S2
M4S1
MH99
MIC18
MK-1
MOC31
TACST-1
TACSTD1
TROP1
hEGP-2
Adenocarcinoma-associated antigen
CD326 antigen
Cell surface glycoprotein Trop-1
Epithelial cell surface antigen
Epithelial glycoprotein
KS 1/4 antigen
Major gastrointestinal tumor-associated protein GA733-2
antigen identified by monoclonal antibody AUA1
carcinoma-associated antigen GA733-2
epithelial cell adhesion molecule
human epithelial glycoprotein-2
membrane component, chromosome 4, surface marker (35kD glycoprotein)
tumor-associated calcium signal transducer 1

EPCAM Gene

protein-coding GIFtS: 56

Aliases & Descriptionsfor EPCAM

Summariesfor EPCAM

Genomic Locationfor EPCAM

Proteinsfor EPCAM

Protein Domains/Familiesfor EPCAM

Gene Functionfor EPCAM

Pathways & Interactionsfor EPCAM

Drugs & Compoundsfor EPCAM

Transcriptsfor EPCAM

Expression for EPCAM

Orthologsfor EPCAM

Paralogsfor EPCAM

SNPs/Variantsfor EPCAM

Disorders & Mutationsfor EPCAM

Medical Newsfor EPCAM

Publicationsfor EPCAM

Search for EPCAM

Genome Databases showing EPCAM

Other Databases showing EPCAM

Specialized Databases showing EPCAM

Licensable Technologiesfor EPCAM

Servicesfor EPCAM

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for EPCAM

Summaries
for EPCAM

Genomic Location
for EPCAM

Proteins
for EPCAM

Protein Domains/
Families
for EPCAM

Gene Function
for EPCAM

Pathways & Interactions
for EPCAM

Drugs & Compounds
for EPCAM

Transcripts
for EPCAM

Expression
for EPCAM

Orthologs
for EPCAM

Paralogs
for EPCAM

SNPs/Variants
for EPCAM

Disorders & Mutations
for EPCAM

Medical News
for EPCAM

Publications
for EPCAM

Licensable Technologies
for EPCAM

Services
for EPCAM