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Aliases for LYRM9 Gene

Aliases for LYRM9 Gene

  • LYR Motif Containing 9 2 3 5
  • C17orf108 3 4
  • Chromosome 17 Open Reading Frame 108 2
  • LYR Motif-Containing Protein 9 3
  • UPF0631 Protein C17orf108 3
  • HSD24 3

External Ids for LYRM9 Gene

Previous HGNC Symbols for LYRM9 Gene

  • C17orf108

Previous GeneCards Identifiers for LYRM9 Gene

  • GC17M026206

Summaries for LYRM9 Gene

GeneCards Summary for LYRM9 Gene

LYRM9 (LYR Motif Containing 9) is a Protein Coding gene. An important paralog of this gene is ENSG00000266202.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LYRM9 Gene

Genomics for LYRM9 Gene

Regulatory Elements for LYRM9 Gene

Enhancers for LYRM9 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around LYRM9 on UCSC Golden Path with GeneCards custom track

Promoters for LYRM9 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for LYRM9 Gene

27,878,314 bp from pter
27,894,752 bp from pter
16,439 bases
Minus strand

Genomic View for LYRM9 Gene

Genes around LYRM9 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LYRM9 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LYRM9 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LYRM9 Gene

Proteins for LYRM9 Gene

  • Protein details for LYRM9 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    LYR motif-containing protein 9
    Protein Accession:
    Secondary Accessions:
    • A6NJT7
    • Q6X7B8

    Protein attributes for LYRM9 Gene

    78 amino acids
    Molecular mass:
    9374 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAP20058.1; Type=Erroneous translation; Note=Wrong choice of CDS.; Evidence={ECO:0000305}; Sequence=EAW51051.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for LYRM9 Gene

Post-translational modifications for LYRM9 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for LYRM9 Gene

No data available for DME Specific Peptides for LYRM9 Gene

Domains & Families for LYRM9 Gene

Gene Families for LYRM9 Gene

Protein Domains for LYRM9 Gene


Suggested Antigen Peptide Sequences for LYRM9 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the complex I LYR family. LYRM9 subfamily.
  • Belongs to the complex I LYR family. LYRM9 subfamily.
genes like me logo Genes that share domains with LYRM9: view

Function for LYRM9 Gene

Phenotypes for LYRM9 Gene

genes like me logo Genes that share phenotypes with LYRM9: view

Animal Models for LYRM9 Gene

MGI Knock Outs for LYRM9:

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for LYRM9 Gene

Localization for LYRM9 Gene

Subcellular locations from

Jensen Localization Image for LYRM9 Gene COMPARTMENTS Subcellular localization image for LYRM9 gene
Compartment Confidence
mitochondrion 3
cytosol 1
extracellular 1
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for LYRM9 Gene

Pathways & Interactions for LYRM9 Gene

SuperPathways for LYRM9 Gene

No Data Available

Interacting Proteins for LYRM9 Gene

Gene Ontology (GO) - Biological Process for LYRM9 Gene


No data available for Pathways by source and SIGNOR curated interactions for LYRM9 Gene

Drugs & Compounds for LYRM9 Gene

No Compound Related Data Available

Transcripts for LYRM9 Gene

Unigene Clusters for LYRM9 Gene

LYR motif containing 9:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for LYRM9 Gene

No ASD Table

Relevant External Links for LYRM9 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for LYRM9 Gene

mRNA expression in normal human tissues for LYRM9 Gene

Protein differential expression in normal tissues from HIPED for LYRM9 Gene

This gene is overexpressed in Peripheral blood mononuclear cells (42.1) and Frontal cortex (13.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for LYRM9 Gene

NURSA nuclear receptor signaling pathways regulating expression of LYRM9 Gene:


SOURCE GeneReport for Unigene cluster for LYRM9 Gene:

genes like me logo Genes that share expression patterns with LYRM9: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for LYRM9 Gene

Orthologs for LYRM9 Gene

This gene was present in the common ancestor of chordates.

Orthologs for LYRM9 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LYRM9 34
  • 90.6 (n)
  • 93.59 (a)
LYRM9 35
  • 94 (a)
(Canis familiaris)
Mammalia LYRM9 34
  • 94.44 (n)
  • 97.44 (a)
-- 35
  • 97 (a)
(Mus musculus)
Mammalia Lyrm9 34
  • 89.74 (n)
  • 91.03 (a)
Lyrm9 16
Lyrm9 35
  • 91 (a)
(Pan troglodytes)
Mammalia LYRM9 34
  • 99.15 (n)
  • 98.72 (a)
-- 35
  • 76 (a)
(Rattus norvegicus)
Mammalia Lyrm9 34
  • 86.32 (n)
  • 91.03 (a)
(Monodelphis domestica)
Mammalia -- 35
  • 76 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 83 (a)
(Gallus gallus)
Aves LYRM9 34
  • 75.76 (n)
  • 81.82 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia lyrm9 34
  • 72.65 (n)
  • 75.64 (a)
(Danio rerio)
Actinopterygii lyrm9 34
  • 66.23 (n)
  • 64.94 (a)
lyrm9 35
  • 64 (a)
Species where no ortholog for LYRM9 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for LYRM9 Gene

Gene Tree for LYRM9 (if available)
Gene Tree for LYRM9 (if available)

Paralogs for LYRM9 Gene

Paralogs for LYRM9 Gene Pseudogenes for LYRM9 Gene

genes like me logo Genes that share paralogs with LYRM9: view

Variants for LYRM9 Gene

Sequence variations from dbSNP and Humsavar for LYRM9 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs15133 -- 27,878,616(+) AGGGA(A/T)GTGCC utr-variant-3-prime
rs1053201 -- 27,878,504(-) GGGAT(C/T)TGAGT utr-variant-3-prime
rs4063521 -- 27,893,329(+) CAGGG(G/T)AACGC upstream-variant-2KB, utr-variant-5-prime
rs3751972 -- 27,879,388(+) AATGG(A/C)TCTTC utr-variant-3-prime
rs3751973 -- 27,879,721(+) GATAG(A/T)GATAA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for LYRM9 Gene

Variant ID Type Subtype PubMed ID
esv1008106 CNV deletion 20482838
nsv2015 CNV deletion 18451855

Variation tolerance for LYRM9 Gene

Residual Variation Intolerance Score: 84% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.75; 15.88% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for LYRM9 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LYRM9 Gene

Disorders for LYRM9 Gene

Relevant External Links for LYRM9

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for LYRM9 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for LYRM9 Gene

Publications for LYRM9 Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 65
  2. Fraction of exhaled nitric oxide values in childhood are associated with 17q11.2-q12 and 17q12-q21 variants. (PMID: 24315451) van der Valk R.J. … de Jongste J.C. (J. Allergy Clin. Immunol. 2014) 3 65
  3. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 4 65
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 65

Products for LYRM9 Gene

Sources for LYRM9 Gene

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