Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

LYRM7 Gene

protein-coding   GIFtS: 42
GCID: GC05P130536

LYR Motif Containing 7

(Previous names: chromosome 5 open reading frame 31, Lyrm7 homolog (mouse))
(Previous symbol: C5orf31)
  Search for LYRM7
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
LYR Motif Containing 71 2     Chromosome 5 Open Reading Frame 311
C5orf311 2 3     Lyrm7 Homolog (Mouse)1
MZM1L2 3     Complex III Assembly Factor LYRM72
LYR Motif-Containing Protein 72 3     Lyrm7 Homolog2

External Ids:    HGNC: 280721   Entrez Gene: 906242   Ensembl: ENSG000001866877   UniProtKB: Q5U5X03   

Export aliases for LYRM7 gene to outside databases

Previous GC identifer: GC05P125697


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for LYRM7 Gene: 
LYRM7 (LYR motif containing 7) is a protein-coding gene.

UniProtKB/Swiss-Prot: LYRM7_HUMAN, Q5U5X0
Function: Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII)
complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it
prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner
membrane




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000005.9  NC_018916.2  NT_034772.6  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the LYRM7 gene promoter:
         STAT1   Sox5   GATA-3   ATF-2   E4BP4   Evi-1   MZF-1   Nkx6-1   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidLYRM7 promoter sequence
   Search SABiosciences Chromatin IP Primers for LYRM7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LYRM7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 5q23.3   Ensembl cytogenetic band:  5q23.3   HGNC cytogenetic band: 5q31.1

LYRM7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
LYRM7 gene location

GeneLoc information about chromosome 5         GeneLoc Exon Structure

GeneLoc location for GC05P130536:  view genomic region     (about GC identifiers)

Start:
130,506,503 bp from pter      End:
130,541,119 bp from pter
Size:
34,617 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: LYRM7_HUMAN, Q5U5X0 (See protein sequence)
Recommended Name: Complex III assembly factor LYRM7  
Size: 104 amino acids; 11955 Da
Subunit: Interacts with UQCRFS1
Subcellular location: Mitochondrion matrix
Secondary accessions: A8MPQ9 Q86Y68

Explore the universe of human proteins at neXtProt for LYRM7: NX_Q5U5X0

Explore proteomics data for LYRM7 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q5U5X0

  • LYRM7 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    LYRM7 Protein Expression
    REFSEQ proteins: NP_859056.2  
    ENSEMBL proteins: 
     ENSP00000368688   ENSP00000423283   ENSP00000423991  

    Human Recombinant Protein Products for LYRM7: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for LYRM7
    OriGene Custom MassSpec 
    OriGene Custom Protein Services for LYRM7
    GenScript Custom Purified and Recombinant Proteins Services for LYRM7
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for LYRM7 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion ----
    GO:0005759mitochondrial matrix IEA--

    LYRM7 for ontologies           About GeneDecksing



    LYRM7 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for LYRM7
    GenScript Custom Superior Antibodies Services for LYRM7
    Novus Biologicals LYRM7 Antibody
    Abcam antibodies for LYRM7
    Cloud-Clone Corp. Antibodies for LYRM7 
    Search ThermoFisher Antibodies for LYRM7
    Search LSBio for Antibodies for LYRM7 

    Assay Products for LYRM7: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for LYRM7
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for LYRM7
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for LYRM7 
    Cloud-Clone Corp. CLIAs for LYRM7


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    LYRM: LYR motif containing

    1 InterPro protein domain:
     IPR008011 Complex1_LYR

    Graphical View of Domain Structure for InterPro Entry Q5U5X0

    ProtoNet protein and cluster: Q5U5X0

    UniProtKB/Swiss-Prot: LYRM7_HUMAN, Q5U5X0
    Similarity: Belongs to the complex I LYR family


    LYRM7 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: LYRM7_HUMAN, Q5U5X0
    Function: Assembly factor required for Rieske Fe-S protein UQCRFS1 incorporation into the cytochrome b-c1 (CIII)
    complex. Functions as a chaperone, binding to this subunit within the mitochondrial matrix and stabilizing it
    prior to its translocation and insertion into the late CIII dimeric intermediate within the mitochondrial inner
    membrane

    Phenotypes:
         1 GenomeRNAi human phenotype for LYRM7:

     Increased homologous recombina 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for LYRM7 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for LYRM7

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for LYRM7 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for LYRM7 

    miRNA
    Products:
        
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat LYRM7
    8/28 QIAGEN miScript miRNA Assays for microRNAs that regulate LYRM7 (see all 28):
    hsa-miR-607 hsa-miR-4311 hsa-miR-539 hsa-miR-520d-5p hsa-miR-548v hsa-miR-192 hsa-miR-1257 hsa-miR-373*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for LYRM7
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LYRM7

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for LYRM7
    Sirion Biotech Customized adenovirus for overexpression of LYRM7

    Clone
    Products:
         
    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene clones in human, mouse for LYRM7 (see all 6)
    OriGene ORF clones in mouse, rat for LYRM7
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: LYRM7 (NM_181705)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for LYRM7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LYRM7
    Sirion Biotech Customized lentivirus for stable overexpression of LYRM7 
                         Customized lentivirus expression plasmids for stable overexpression of LYRM7 

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for LYRM7
    Search LifeMap BioReagents cell lines for LYRM7
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LYRM7


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for LYRM7

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for LYRM7

    Search CenterWatch for drugs/clinical trials and news about LYRM7

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for LYRM7 gene: 
    NM_181705.2  

    Unigene Cluster for LYRM7:

    LYR motif containing 7
    Hs.115467  [show with all ESTs]
    Unigene Representative Sequence: NM_181705
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000379380(uc003kvg.1) ENST00000510516 ENST00000507584 ENST00000521227

    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat LYRM7
    8/28 QIAGEN miScript miRNA Assays for microRNAs that regulate LYRM7 (see all 28):
    hsa-miR-607 hsa-miR-4311 hsa-miR-539 hsa-miR-520d-5p hsa-miR-548v hsa-miR-192 hsa-miR-1257 hsa-miR-373*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for LYRM7
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LYRM7
    Clone
    Products:
         
    OriGene clones in human, mouse for LYRM7 (see all 6)
    OriGene ORF clones in mouse, rat for LYRM7
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: LYRM7 (NM_181705)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for LYRM7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LYRM7
    Sirion Biotech Customized lentivirus for stable overexpression of LYRM7 
                         Customized lentivirus expression plasmids for stable overexpression of LYRM7 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for LYRM7
    OriGene qSTAR qPCR primer pairs in human, mouse for LYRM7
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat LYRM7
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LYRM7
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LYRM7

    Additional mRNA sequence: 

    AK000803.1 AK056991.1 BC022429.1 BC037930.1 BC047079.1 

    12 DOTS entries:

    DT.202732  DT.99940844  DT.105355  DT.87015741  DT.100747273  DT.411620  DT.95272690  DT.99987657 
    DT.40264062  DT.425193  DT.120841943  DT.120841981 

    24/72 AceView cDNA sequences (see all 72):

    BM804279 AI816072 AA416991 AK000803 BE907078 AA383033 AA470056 AW675551 
    BU753991 BI597308 BG251501 NM_181705 BC037930 BG292249 AL598635 BI599224 
    H49981 BU945402 BI603906 BM874669 BG203284 BQ010941 BI224922 BG714922 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for LYRM7    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2a · 2b ^ 3 ^ 4 ^ 5a · 5b · 5c · 5d
    SP1:                                                                              
    SP2:                                                                              
    SP3:                          -                                                   
    SP4:                                                  -                           
    SP5:                                            -     -                           


    ECgene alternative splicing isoforms for LYRM7

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    LYRM7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AATTCAGGTC
    LYRM7 Expression
    About this image


    See LYRM7 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for LYRM7

    SOURCE GeneReport for Unigene cluster: Hs.115467
        SABiosciences Custom PCR Arrays for LYRM7
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for LYRM7
    OriGene qSTAR qPCR primer pairs in human, mouse for LYRM7
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat LYRM7
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LYRM7
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LYRM7
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LYRM7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for LYRM7 gene from 6/11 species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Lyrm71 , 5 LYR motif containing 71, 5 86.22(n)1
    83.65(a)1
      11 (32.13 cM)5
    755301  NM_029327.31  NP_083603.21 
     548268665 
    chicken
    (Gallus gallus)
    Aves LYRM71 Lyrm7 homolog (mouse) 72.11(n)
    70.41(a)
      768932  XM_001231595.2  XP_001231596.1 
    lizard
    (Anolis carolinensis)
    Reptilia LYRM76
    Uncharacterized protein
    67(a)
    1 ↔ 1
    2(31309064-31315144)
    African clawed frog
    (Xenopus laevis)
    Amphibia AW638504.12   -- 80.09(n)    AW638504.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1655971 zgc:165597 61.81(n)
    61.17(a)
      100002948  NM_001098759.1  NP_001092229.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG341506
    --
    29(a)
    1 ↔ 1
    3R(20639984-20640652)


    ENSEMBL Gene Tree for LYRM7 (if available)
    TreeFam Gene Tree for LYRM7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/702 SNPs in LYRM7 are shown (see all 702)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 5 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs100432441,2
    C,F--130504709(+) TGAGAT/CGCAAA 1 -- us2k17Minor allele frequency- C:0.33NA WA CSA 246
    rs100646261,2
    C,F--130504768(+) aggggG/Tcaaag 1 -- us2k1 tfbs32Minor allele frequency- T:0.24WA 120
    rs1479260331,2
    --130504859(+) GTTGAC/GATGTT 1 -- us2k10--------
    rs1906244291,2
    --130504929(+) GTAGAA/CCCTTG 1 -- us2k10--------
    rs1822919091,2
    --130505029(+) CCATTA/GTTTGG 1 -- us2k10--------
    rs77340191,2
    C,F,A--130505083(+) aaaccA/Ttcttc 1 -- us2k16Minor allele frequency- T:0.19NA WA CSA 246
    rs754185011,2
    F--130505093(+) CAATTT/CTCCTT 1 -- us2k11Minor allele frequency- C:0.02WA 118
    rs1174791771,2
    C,F--130505100(+) CCTTAC/TGCTGG 1 -- us2k11Minor allele frequency- T:0.03EA 120
    rs1142082151,2
    C,F--130505136(+) TCTACA/GTGTTC 1 -- us2k11Minor allele frequency- G:0.07WA 118
    rs77341771,2
    C,F,A,H--130505154(+) actgcC/Tcttac 1 -- us2k117Minor allele frequency- T:0.24NS EA NA WA CSA 1866

    HapMap Linkage Disequilibrium report for LYRM7 (130506503 - 130541119 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for LYRM7:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv882884CNV Loss21882294
    dgv6326n71CNV Loss21882294
    nsv882885CNV Gain21882294
    nsv882883CNV Gain21882294
    dgv1852e1CNV Complex17122850

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing LYRM7
    DNA2.0 Custom Variant and Variant Library Synthesis for LYRM7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    LYRM7 for disorders           About MalaCards

    LYRM7 for disorders           About GeneDecksing

    Genetic Association Database (GAD): LYRM7
    Human Genome Epidemiology (HuGE) Navigator: LYRM7 (2 documents)

    Export disorders for LYRM7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for LYRM7 gene, integrated from 9 sources (see all 11):
    (articles sorted by number of sources associating them with LYRM7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. LYRM7/MZM1L is a UQCRFS1 chaperone involved in the last steps of mitochondrial Complex III assembly in human cells. (PubMed id 23168492)1, 2, 3 Sanchez E....Fernandez-Vizarra E. (2013)
    2. Genetic variants in nuclear-encoded mitochondrial gen es influence AIDS progression. (PubMed id 20877624)1, 4 Hendrickson S.L....O'Brien S.J. (2010)
    3. Coeliac disease associated risk variants in TNFAIP3 and REL implicate altered NF-{kappa}B signalling. (PubMed id 19240061)1, 4 Trynka G....Wijmenga C. (2009)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    5. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    6. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
    7. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    8. Framingham Heart Study 100K Project: genome-wide associations for blood pressure and arterial stiffness. (PubMed id 17903302)4 Levy D....Mitchell G.F. (2007)
    9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (2004)
    10. The DNA sequence and comparative analysis of human chromosome 5. (PubMed id 15372022)2 Schmutz J.... Rubin E.M. (2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 90624 HGNC: 28072 AceView: LOC90624 Ensembl:ENSG00000186687 euGenes: HUgn90624
    ECgene: LYRM7 H-InvDB: LYRM7

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for LYRM7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for LYRM7 gene:
    Search GeneIP for patents involving LYRM7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
     Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for LYRM7  
     OriGene qPCR primer pairs and template standards for LYRM7   OriGene Protein Over-expression Lysate for LYRM7  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for LYRM7  
     OriGene qSTAR qPCR primer pairs in human, mouse for LYRM7   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for LYRM7   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for LYRM7   OriGene Custom Protein Services for LYRM7  

     
     
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat LYRM7
     QIAGEN SeqTarget long-range PCR primers for resequencing LYRM7
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LYRM7
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LYRM7
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LYRM7
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LYRM7
     GenScript Custom Purified and Recombinant Proteins Services for LYRM7 GenScript cDNA clones with any tag delivered in your preferred vector for LYRM7
     GenScript Custom Assay Services for LYRM7 GenScript Custom Superior Antibodies Services for LYRM7
     GenScript Custom overexpressing Cell Line Services for LYRM7 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in LYRM7 promoter
     Search Chromatin IP Primers for LYRM7
     RT2 qPCR Primer Assay in human, mouse, rat LYRM7
     Search GNC Networks for LYRM7
     SABiosciences Custom PCR Arrays for LYRM7
     Search Tocris compounds for LYRM7
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     LYRM7 antibodies
     Antibodies for LYRM7
     See all of Abcam's Antibodies, Kits and Proteins for LYRM7
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Proteins for LYRM7
     Antibodies for LYRM7
     ELISAs for LYRM7
     CLIAs for LYRM7
     Search LifeMap BioReagents cell lines for LYRM7
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LYRM7
     Browse SwitchGear 3'UTR luciferase reporter plasmids for LYRM7
     SwitchGear Promoter luciferase reporter plasmids for LYRM7
     Search ThermoFisher Antibodies for LYRM7
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LYRM7
     inGenious Targeting Laboratory - Custom generated mouse model solutions for LYRM7
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for LYRM7
    Customized:
     lentivirus for stable overexpression of LYRM7
     lentivirus expression plasmids for stable overexpression of LYRM7
     adenovirus for overexpression of LYRM7
     Search LSBio for Antibodies for LYRM7
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
           
    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

    View Random Gene

    Category
    (GIFtS: 73)
    transforming growth factor, beta 1
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      LYRM7 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4