External Ids for LYPD8 Gene
Previous GeneCards Identifiers for LYPD8 Gene
GeneCards Summary for LYPD8 Gene
LYPD8 (LY6/PLAUR Domain Containing 8) is a Protein Coding gene. Among its related pathways are Metabolism of proteins and Post-translational modification- synthesis of GPI-anchored proteins.
UniProtKB/Swiss-Prot for LYPD8 Gene
Secreted protein specifically required to prevent invasion of Gram-negative bacteria in the inner mucus layer of the colon epithelium, a portion of the large intestine which is free of commensal microbiota. Prevents invasion of flagellated microbiota by binding to the flagellum of bacteria, such as P.mirabilis, thereby inhibiting bacterial motility in the intestinal lumen. Segregation of intestinal bacteria and epithelial cells in the colon is required to preserve intestinal homeostasis.