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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

LYAR Gene

protein-coding   GIFtS: 51
GCID: GC04M004269

Ly1 Antibody Reactive

(Previous name: Ly1 antibody reactive homolog (mouse))
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Ly1 Antibody Reactive1 2
Ly1 Antibody Reactive Homolog (Mouse)1
ZC2HC22
ZLYAR2
Cell Growth-Regulating Nucleolar Protein2
Ly1 Antibody Reactive Homolog2

External Ids:    HGNC: 260211   Entrez Gene: 556462   Ensembl: ENSG000001452207   UniProtKB: Q9NX583   

Export aliases for LYAR gene to outside databases

Previous GC identifers: GC04M004146 GC04M004262 GC04M004333 GC04M004387 GC04M004206


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for LYAR Gene: 
LYAR (Ly1 antibody reactive) is a protein-coding gene. Diseases associated with LYAR include colon adenocarcinoma, and adenocarcinoma. GO annotations related to this gene include metal ion binding.

Gene Wiki entry for LYAR Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000004.11  NT_006051.18  NC_018915.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the LYAR gene promoter:
         TBP   AML1a   Ik-2   MyoD   Meis-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidLYAR promoter sequence
   Search SABiosciences Chromatin IP Primers for LYAR

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LYAR


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 4p16.3   Ensembl cytogenetic band:  4p16.3   HGNC cytogenetic band: 4p16.3

LYAR Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
LYAR gene location

GeneLoc information about chromosome 4         GeneLoc Exon Structure

GeneLoc location for GC04M004269:  view genomic region     (about GC identifiers)

Start:
4,269,428 bp from pter      End:
4,291,896 bp from pter
Size:
22,469 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: LYAR_HUMAN, Q9NX58 (See protein sequence)
Recommended Name: Cell growth-regulating nucleolar protein  
Size: 379 amino acids; 43615 Da
Subcellular location: Nucleus, nucleolus
Secondary accessions: D3DVS4 Q6FI78 Q9NYS1

Explore the universe of human proteins at neXtProt for LYAR: NX_Q9NX58

Explore proteomics data for LYAR at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NX58

  • LYAR Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    LYAR Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001139197.1  NP_060286.1  

    ENSEMBL proteins: 
     ENSP00000345917   ENSP00000420902   ENSP00000397367  

    Human Recombinant Protein Products for LYAR: 
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    OriGene Protein Over-expression Lysate for LYAR
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    Novus Biologicals LYAR Protein
    Novus Biologicals LYAR Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for LYAR 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005730nucleolus IDA--

    LYAR for ontologies           About GeneDecksing



    LYAR Antibody Products: 
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    Browse Kits and Assays available from EMD Millipore
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    Cloud-Clone Corp. ELISAs for LYAR 
    Cloud-Clone Corp. CLIAs for LYAR


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ZC2HC: Zinc fingers, C2HC-type containing

    1 InterPro protein domain:
     IPR014898 Znf_C2H2_LYAR

    Graphical View of Domain Structure for InterPro Entry Q9NX58

    ProtoNet protein and cluster: Q9NX58

    UniProtKB/Swiss-Prot: LYAR_HUMAN, Q9NX58
    Similarity: Contains 2 C2HC-type zinc fingers


    LYAR for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0046872metal ion binding IEA--
         
    LYAR for ontologies           About GeneDecksing


    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for LYAR 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for LYAR

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for LYAR 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for LYAR 

    miRNA
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    SwitchGear 3'UTR luciferase reporter plasmidLYAR 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for LYAR
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LYAR

    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 2): LYAR (NM_001145725)
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                         Customized lentivirus expression plasmids for stable overexpression of LYAR 

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    Search LifeMap BioReagents cell lines for LYAR
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LYAR


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for LYAR

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    5/181 Interacting proteins for LYAR (Q9NX582, 3 ENSP000003459174) via UniProtKB, MINT, STRING, and/or I2D (see all 181)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    GNL3Q9BVP22, 3, ENSP000003957724MINT-6488590 I2D: score=1 STRING: ENSP00000395772
    RPL21P467782, 3, ENSP000003460274MINT-6488590 I2D: score=1 STRING: ENSP00000346027
    ZBTB16Q055162, 3MINT-65657 I2D: score=5 
    ZHX1Q9UKY12, 3MINT-65658 I2D: score=5 
    RPL18AQ025432, 3MINT-6488590 I2D: score=2 
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for LYAR

    Search CenterWatch for drugs/clinical trials and news about LYAR

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for LYAR gene (2 alternative transcripts): 
    NM_001145725.1  NM_017816.2  

    Unigene Cluster for LYAR:

    Ly1 antibody reactive
    Hs.425427  [show with all ESTs]
    Unigene Representative Sequence: AK000432
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000502917 ENST00000343470(uc011bvx.2 uc003ght.3) ENST00000513174
    ENST00000452476(uc011bvy.2)
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat LYAR
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate LYAR
    SwitchGear 3'UTR luciferase reporter plasmidLYAR 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for LYAR
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LYAR
    Clone
    Products:
         
    OriGene clones in human, mouse for LYAR (see all 14)
    OriGene ORF clones in mouse, rat for LYAR
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): LYAR (NM_001145725)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for LYAR
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LYAR
    Sirion Biotech Customized lentivirus for stable overexpression of LYAR 
                         Customized lentivirus expression plasmids for stable overexpression of LYAR 
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for LYAR
    OriGene qSTAR qPCR primer pairs in human, mouse for LYAR
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat LYAR
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LYAR
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LYAR

    Additional mRNA sequence: 

    AF229835.1 AK000432.1 AK290750.1 AL136750.1 BC015796.2 CR533548.1 

    8 DOTS entries:

    DT.410315  DT.100776371  DT.102823585  DT.92434601  DT.92434604  DT.95165954  DT.100776370  DT.100035677 

    24/111 AceView cDNA sequences (see all 111):

    NM_017816 BQ220279 AI708352 CR616708 AI688625 AK000432 CB135957 AW294480 
    CR605760 AL136750 AI183462 BF197522 AI382479 BP354367 BM974170 CR609495 
    AA424566 AF229835 BM823927 BQ439081 BM798263 BM460597 CA418080 AA424663 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for LYAR    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12
    SP1:        -                                                                     
    SP2:                                                                              
    SP3:                                                                              


    ECgene alternative splicing isoforms for LYAR

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    LYAR expression in normal human tissues (normalized intensities)      LYAR embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGAAATCTC
    LYAR Expression
    About this image


    LYAR expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Ovary (Reproductive System)
             Secondary Oocyte Antral Follicle
     
     Liver (Hepatobiliary System)
             Liver Lobule
     
     Gonad
             Secondary Oocyte Antral Follicle
     
     Eye (Sensory Organs)
             Mature Rod Cells Outer Nuclear Layer
     
     Testis (Reproductive System)

    See LYAR Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for LYAR

    SOURCE GeneReport for Unigene cluster: Hs.425427
        SABiosciences Custom PCR Arrays for LYAR
    Primer
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    OriGene qPCR primer pairs and template standards for LYAR
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LYAR

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for LYAR gene from 10/20 species (see all 20)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Lyar1 , 5 Ly1 antibody reactive clone1, 5 77.87(n)1
    75.2(a)1
      5 (20.29 cM)5
    170891  NM_025281.31  NP_079557.21 
     382204705 
    chicken
    (Gallus gallus)
    Aves LYAR1 Ly1 antibody reactive homolog (mouse) 67.04(n)
    60.28(a)
      422846  XM_420792.3  XP_420792.2 
    lizard
    (Anolis carolinensis)
    Reptilia LYAR6
    --
    --
    85(a)
    37(a)
    many → 1
    many → 1
    GL343236.1(653554-660176)
    GL343236.1(641567-648588)
    African clawed frog
    (Xenopus laevis)
    Amphibia BU901561.12   -- 78.68(n)    BU901561.1 
    zebrafish
    (Danio rerio)
    Actinopterygii AF332588.12   -- 73.8(n)   393652  AF332588.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG129091 CG12909 48.83(n)
    40.33(a)
      36087  NM_136729.3  NP_610573.1 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_C16C10.81 Protein C16C10.8 48.86(n)
    40.64(a)
      175531  NM_065428.3  NP_497829.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes (YCR087C-A)4 Putative protein of unknown function; green fluorescent more   --   3(264467-264006) 850449  NP_010011.1 
    thale cress
    (Arabidopsis thaliana)
    eudicotyledons AT2G193851 zinc ion binding protein 45.93(n)
    37.33(a)
      816457  NM_127496.2  NP_565451.1 
    rice
    (Oryza sativa)
    Liliopsida Os01g05832001 hypothetical protein 42.25(n)
    28.09(a)
      4324202  NM_001049951.1  NP_001043416.2 


    ENSEMBL Gene Tree for LYAR (if available)
    TreeFam Gene Tree for LYAR (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for LYAR gene

    LYAR for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for LYAR
    PGOHUM00000240114


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/691 SNPs in LYAR are shown (see all 691)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 4 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0230814
    ----see VAR_0230812 H R mis40--------
    rs778498841,2
    --4222128(+) CAGTAT/ATTTTC 1 -- int11Minor allele frequency- A:0.00CSA 1
    rs29801591,2
    --4229455(+) gaggcG/Aagtgg 1 -- us2k11Minor allele frequency- A:0.50NA 2
    rs29164321,2
    --4229456(-) tccacT/Acgcct 1 -- us2k11Minor allele frequency- A:0.50NA 2
    rs1160971191,2
    C,F--4246440(+) GGCACA/CGTGGC 1 -- int11Minor allele frequency- C:0.01NA 120
    rs68297911,2
    C,F--4246487(+) caggcG/Agatca 1 -- int12Minor allele frequency- A:0.50WA 4
    rs1874289721,2
    --4246659(+) TGAGAC/TTGTGC 1 -- int10--------
    rs1906582101,2
    --4246684(+) CTGGGC/TGACAG 1 -- int10--------
    rs731940781,2
    --4246813(+) AAAAAC/TTTTTT 1 -- int10--------
    rs802219561,2
    C,F--4246887(+) GAATAT/CATTTT 1 -- ut311Minor allele frequency- C:0.02NA 120

    HapMap Linkage Disequilibrium report for LYAR (4269428 - 4291896 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for LYAR:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv10437CNV Gain18304495
    dgv1566e1CNV Complex17122850

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing LYAR
    DNA2.0 Custom Variant and Variant Library Synthesis for LYAR

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    3 diseases for LYAR:    About MalaCards
    colon adenocarcinoma    adenocarcinoma    breast cancer


    LYAR for disorders           About GeneDecksing


    Export disorders for LYAR gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for LYAR gene, integrated from 9 sources (see all 31):
    (articles sorted by number of sources associating them with LYAR)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (2001)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Functional proteomic analysis of human nucleolus. (PubMed id 12429849)1, 2 Scherl A.... Diaz J.-J. (2002)
    5. LYAR, a novel nucleolar protein with zinc finger DNA-binding motifs, is involved in cell growth regulation. (PubMed id 8491376)1, 3 Su L....Weissman I.L. (1993)
    6. VCP phosphorylation-dependent interaction partners pre vent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (2013)
    7. Targeted ubiquitination and degradation of G-protein-c oupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex. (PubMed id 22952844)1 Wu Z....Ma L. (2012)
    8. Charting the landscape of tandem BRCT domain-mediated protein interactions. (PubMed id 22990118)1 Woods N.T....Monteiro A.N. (2012)
    9. Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S....Dorf M.E. (2011)
    10. Interactome study suggests multiple cellular functions of hepatoma-derived growth factor (HDGF). (PubMed id 21907836)1 Zhao J....Yang P. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
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    Aliases
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    NCBI Bookshelf
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 55646 HGNC: 26021 AceView: LYAR Ensembl:ENSG00000145220 euGenes: HUgn55646
    ECgene: LYAR H-InvDB: LYAR

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for LYAR Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for LYAR gene:
    Search GeneIP for patents involving LYAR

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

     
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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