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Aliases for LY75-CD302 Gene

Aliases for LY75-CD302 Gene

  • LY75-CD302 Readthrough 2 3 5

External Ids for LY75-CD302 Gene

Previous GeneCards Identifiers for LY75-CD302 Gene

  • GC02U902275
  • GC02M160629
  • GC02M160630

Summaries for LY75-CD302 Gene

Entrez Gene Summary for LY75-CD302 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring lymphocyte antigen 75 (LY75) and CD302 molecule (CD302) genes. Alternative splicing results in multiple transcript variants encoding fusion products that share sequence identity with each individual gene product. [provided by RefSeq, Nov 2010]

GeneCards Summary for LY75-CD302 Gene

LY75-CD302 (LY75-CD302 Readthrough) is a Protein Coding gene. An important paralog of this gene is LY75.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LY75-CD302 Gene

Genomics for LY75-CD302 Gene

Regulatory Elements for LY75-CD302 Gene

Enhancers for LY75-CD302 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH02F159932 0.8 Ensembl 12.4 -28.5 -28545 2.2 PKNOX1 TBL1XR1 MTA2 EBF1 SP1 POLR2A EED IKZF1 SPI1 LY75 LY75-CD302 LOC105373717
GH02F159945 0.6 ENCODE 12.4 -42.1 -42090 2.5 JUND JUN STAT3 LY75 LY75-CD302 LOC105373717
GH02F159878 0.7 ENCODE 11.8 +25.4 25391 1.2 TBP PKNOX1 TBL1XR1 BMI1 EBF1 ZIC2 RELA CREM MTA2 ZBED1 LY75 LY75-CD302 WDSUB1 ENSG00000227055
GH02F159902 1.1 ENCODE 0.8 -0.1 -96 4.9 PKNOX1 WRNIP1 SIN3A ARID4B DMAP1 ZNF48 ETS1 ZNF143 SP5 MIER2 LY75 BTF3L4P2 LY75-CD302 LOC105373717
GH02F159895 0.3 FANTOM5 0.4 +9.0 9041 0.1 TBP PKNOX1 MTA2 ZBED1 ASH2L JUNB TBX21 ZBTB40 RELA OSR2 LY75 LY75-CD302 ENSG00000227055
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around LY75-CD302 on UCSC Golden Path with GeneCards custom track

Promoters for LY75-CD302 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000601063 356 2001 TBP PKNOX1 WRNIP1 SIN3A BMI1 ETS1 EGR1 ZNF143 SMAD5 TBX21

Genomic Location for LY75-CD302 Gene

159,768,628 bp from pter
159,904,756 bp from pter
136,129 bases
Minus strand

Genomic View for LY75-CD302 Gene

Genes around LY75-CD302 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LY75-CD302 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LY75-CD302 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LY75-CD302 Gene

Proteins for LY75-CD302 Gene

Post-translational modifications for LY75-CD302 Gene

No Post-translational modifications

Other Protein References for LY75-CD302 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for LY75-CD302 Gene

Domains & Families for LY75-CD302 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for LY75-CD302 Gene

Function for LY75-CD302 Gene

Phenotypes for LY75-CD302 Gene

genes like me logo Genes that share phenotypes with LY75-CD302: view

Animal Model Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LY75-CD302 Gene

Localization for LY75-CD302 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for LY75-CD302 Gene

Pathways & Interactions for LY75-CD302 Gene

SuperPathways for LY75-CD302 Gene

No Data Available

Interacting Proteins for LY75-CD302 Gene

Gene Ontology (GO) - Biological Process for LY75-CD302 Gene


No data available for Pathways by source and SIGNOR curated interactions for LY75-CD302 Gene

Transcripts for LY75-CD302 Gene

mRNA/cDNA for LY75-CD302 Gene

(2) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for LY75-CD302 Gene

No ASD Table

Relevant External Links for LY75-CD302 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for LY75-CD302 Gene

mRNA expression in normal human tissues for LY75-CD302 Gene

genes like me logo Genes that share expression patterns with LY75-CD302: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for LY75-CD302 Gene

Orthologs for LY75-CD302 Gene

This gene was present in the common ancestor of animals.

Orthologs for LY75-CD302 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 35
  • 99 (a)
(Canis familiaris)
Mammalia -- 35
  • 80 (a)
(Bos Taurus)
Mammalia LY75 35
  • 79 (a)
(Mus musculus)
Mammalia Ly75 35
  • 76 (a)
(Monodelphis domestica)
Mammalia -- 35
  • 67 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 57 (a)
(Gallus gallus)
Aves LY75 35
  • 50 (a)
(Anolis carolinensis)
Reptilia -- 35
  • 56 (a)
-- 35
  • 35 (a)
(Danio rerio)
Actinopterygii ly75 35
  • 36 (a)
(Caenorhabditis elegans)
Secernentea clec-48 35
  • 26 (a)
clec-49 35
  • 26 (a)
clec-50 35
  • 26 (a)
clec-52 35
  • 23 (a)
clec-53 35
  • 23 (a)
clec-51 35
  • 22 (a)
clec-148 35
  • 21 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 23 (a)
Species where no ortholog for LY75-CD302 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for LY75-CD302 Gene

Gene Tree for LY75-CD302 (if available)
Gene Tree for LY75-CD302 (if available)

Paralogs for LY75-CD302 Gene

Paralogs for LY75-CD302 Gene

genes like me logo Genes that share paralogs with LY75-CD302: view

Variants for LY75-CD302 Gene

Sequence variations from dbSNP and Humsavar for LY75-CD302 Gene

SNP ID Clin Chr 02 pos Sequence Context AA Info Type
rs10048669 -- 159,813,381(+) tattc(A/G)tttcc intron-variant
rs10084194 -- 159,786,616(+) ggcat(A/G)agcca intron-variant
rs10168271 -- 159,872,675(+) ACATG(C/T)GTGGG intron-variant
rs10168385 -- 159,874,787(+) taaat(A/T)tatgt intron-variant
rs10169681 -- 159,782,065(+) AGTTC(A/G)GCACC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for LY75-CD302 Gene

Variant ID Type Subtype PubMed ID
dgv1176e212 CNV loss 25503493
esv1001679 CNV deletion 20482838
esv1275142 CNV insertion 17803354
esv1586275 CNV insertion 17803354
esv1681534 CNV deletion 17803354
esv2358013 CNV deletion 18987734
esv2665197 CNV deletion 23128226
esv2721034 CNV deletion 23290073
esv3893504 CNV loss 25118596
nsv1010774 CNV gain 25217958
nsv1116803 CNV deletion 24896259
nsv437546 CNV loss 16327808
nsv470497 CNV loss 18288195
nsv834436 CNV loss 17160897

Variation tolerance for LY75-CD302 Gene

Residual Variation Intolerance Score: 26.4% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for LY75-CD302 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LY75-CD302 Gene

Disorders for LY75-CD302 Gene

Relevant External Links for LY75-CD302

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for LY75-CD302 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for LY75-CD302 Gene

Publications for LY75-CD302 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T. … Taylor T.D. (PLoS ONE 2010) 3 64
  2. Hodgkin's lymphoma cell lines express a fusion protein encoded by intergenically spliced mRNA for the multilectin receptor DEC-205 (CD205) and a novel C-type lectin receptor DCL-1. (PMID: 12824192) Kato M. … Hart D.N.J. (J. Biol. Chem. 2003) 3 64

Products for LY75-CD302 Gene

Sources for LY75-CD302 Gene

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