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Aliases for LY75-CD302 Gene

Aliases for LY75-CD302 Gene

  • LY75-CD302 Readthrough 2 3 5

External Ids for LY75-CD302 Gene

Previous GeneCards Identifiers for LY75-CD302 Gene

  • GC02U902275
  • GC02M160629
  • GC02M160630

Summaries for LY75-CD302 Gene

Entrez Gene Summary for LY75-CD302 Gene

  • This locus represents naturally occurring read-through transcription between the neighboring lymphocyte antigen 75 (LY75) and CD302 molecule (CD302) genes. Alternative splicing results in multiple transcript variants encoding fusion products that share sequence identity with each individual gene product. [provided by RefSeq, Nov 2010]

GeneCards Summary for LY75-CD302 Gene

LY75-CD302 (LY75-CD302 Readthrough) is a Protein Coding gene. An important paralog of this gene is LY75.

Additional gene information for LY75-CD302 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LY75-CD302 Gene

Genomics for LY75-CD302 Gene

GeneHancer (GH) Regulatory Elements for LY75-CD302 Gene

Promoters and enhancers for LY75-CD302 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH02I159902 Promoter/Enhancer 1.9 EPDnew Ensembl ENCODE 550.8 -0.1 -96 4.9 PKNOX1 FOXA2 ARID4B SIN3A DMAP1 IRF4 ZNF48 ETS1 ZNF143 ATF7 LY75 LY75-CD302 BTF3L4P2 LOC105373717
GH02I159878 Enhancer 0.7 ENCODE 11.8 +25.4 25391 1.2 PKNOX1 SMAD1 EBF1 BMI1 BATF KLF5 IRF4 RELA NFATC1 ATF7 LY75 LY75-CD302 WDSUB1 ENSG00000227055
GH02I159933 Enhancer 0.6 Ensembl 12.4 -28.9 -28897 0.9 SMARCA5 ZNF687 NR2F1 EBF1 ELF1 DPF2 ATF2 SP1 POLR2A IKZF1 LY75 LY75-CD302 LOC105373717 PLA2R1
GH02I159945 Enhancer 0.5 ENCODE 12.5 -42.1 -42089 2.5 SP1 JUND JUN STAT3 FOSL2 LY75 LY75-CD302 LOC105373717 PLA2R1
GH02I159934 Enhancer 0.2 Ensembl 12.4 -29.5 -29545 0.2 LY75 LY75-CD302 LOC105373717 PLA2R1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data dump

GeneHancers around LY75-CD302 on UCSC Golden Path with GeneCards custom track

Genomic Locations for LY75-CD302 Gene

Genomic Locations for LY75-CD302 Gene
136,129 bases
Minus strand

Genomic View for LY75-CD302 Gene

Genes around LY75-CD302 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LY75-CD302 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LY75-CD302 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LY75-CD302 Gene

Proteins for LY75-CD302 Gene

Post-translational modifications for LY75-CD302 Gene

No Post-translational modifications

Other Protein References for LY75-CD302 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for LY75-CD302 Gene

Domains & Families for LY75-CD302 Gene

Gene Families for LY75-CD302 Gene

Human Protein Atlas (HPA):
  • Predicted membrane proteins

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with LY75-CD302: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for LY75-CD302 Gene

Function for LY75-CD302 Gene

Phenotypes for LY75-CD302 Gene

genes like me logo Genes that share phenotypes with LY75-CD302: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for LY75-CD302 Gene

Localization for LY75-CD302 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LY75-CD302 Gene

Pathways & Interactions for LY75-CD302 Gene

SuperPathways for LY75-CD302 Gene

No Data Available

Interacting Proteins for LY75-CD302 Gene

Gene Ontology (GO) - Biological Process for LY75-CD302 Gene


No data available for Pathways by source and SIGNOR curated interactions for LY75-CD302 Gene

Drugs & Compounds for LY75-CD302 Gene

No Compound Related Data Available

Transcripts for LY75-CD302 Gene

mRNA/cDNA for LY75-CD302 Gene

(2) REFSEQ mRNAs :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for LY75-CD302 Gene

No ASD Table

Relevant External Links for LY75-CD302 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for LY75-CD302 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for LY75-CD302 Gene

genes like me logo Genes that share expression patterns with LY75-CD302: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LY75-CD302 Gene

Orthologs for LY75-CD302 Gene

This gene was present in the common ancestor of animals.

Orthologs for LY75-CD302 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia -- 34
  • 99 (a)
(Canis familiaris)
Mammalia -- 34
  • 80 (a)
(Bos Taurus)
Mammalia LY75 34
  • 79 (a)
(Mus musculus)
Mammalia Ly75 34
  • 76 (a)
(Monodelphis domestica)
Mammalia -- 34
  • 67 (a)
(Ornithorhynchus anatinus)
Mammalia -- 34
  • 57 (a)
(Gallus gallus)
Aves LY75 34
  • 50 (a)
(Anolis carolinensis)
Reptilia -- 34
  • 56 (a)
-- 34
  • 35 (a)
(Danio rerio)
Actinopterygii ly75 34
  • 36 (a)
(Caenorhabditis elegans)
Secernentea clec-48 34
  • 26 (a)
clec-49 34
  • 26 (a)
clec-50 34
  • 26 (a)
clec-52 34
  • 23 (a)
clec-53 34
  • 23 (a)
clec-51 34
  • 22 (a)
clec-148 34
  • 21 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 23 (a)
Species where no ortholog for LY75-CD302 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)

Evolution for LY75-CD302 Gene

Gene Tree for LY75-CD302 (if available)
Gene Tree for LY75-CD302 (if available)

Paralogs for LY75-CD302 Gene

Paralogs for LY75-CD302 Gene

genes like me logo Genes that share paralogs with LY75-CD302: view

Variants for LY75-CD302 Gene

Sequence variations from dbSNP and Humsavar for LY75-CD302 Gene

SNP ID Clin Chr 02 pos Variation AA Info Type
rs1000020040 -- 159,868,591(-) A/T intron_variant
rs1000026673 -- 159,789,003(-) T/C intron_variant
rs1000049809 -- 159,868,944(-) A/G intron_variant
rs1000050244 -- 159,869,602(-) C/T intron_variant
rs1000054858 -- 159,880,291(-) A/C intron_variant

Structural Variations from Database of Genomic Variants (DGV) for LY75-CD302 Gene

Variant ID Type Subtype PubMed ID
dgv1176e212 CNV loss 25503493
esv1001679 CNV deletion 20482838
esv1275142 CNV insertion 17803354
esv1586275 CNV insertion 17803354
esv1681534 CNV deletion 17803354
esv2358013 CNV deletion 18987734
esv2665197 CNV deletion 23128226
esv2721034 CNV deletion 23290073
esv3893504 CNV loss 25118596
nsv1010774 CNV gain 25217958
nsv1116803 CNV deletion 24896259
nsv437546 CNV loss 16327808
nsv470497 CNV loss 18288195
nsv834436 CNV loss 17160897

Variation tolerance for LY75-CD302 Gene

Residual Variation Intolerance Score: 26.4% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for LY75-CD302 Gene

Human Gene Mutation Database (HGMD)
SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LY75-CD302 Gene

Disorders for LY75-CD302 Gene

Additional Disease Information for LY75-CD302

No disorders were found for LY75-CD302 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for LY75-CD302 Gene

Publications for LY75-CD302 Gene

  1. Expression of conjoined genes: another mechanism for gene regulation in eukaryotes. (PMID: 20967262) Prakash T … Taylor TD (PloS one 2010) 3 58
  2. Hodgkin's lymphoma cell lines express a fusion protein encoded by intergenically spliced mRNA for the multilectin receptor DEC-205 (CD205) and a novel C-type lectin receptor DCL-1. (PMID: 12824192) Kato M … Hart DN (The Journal of biological chemistry 2003) 3 58

Products for LY75-CD302 Gene

Sources for LY75-CD302 Gene

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