LTK Gene
protein-coding GIFtS: 62
GCID: GC15M041795
|
|
leukocyte receptor tyrosine kinase(Previous name: leukocyte tyrosine kinase )
| |
Aliases
for LTK gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Leukocyte Receptor Tyrosine Kinase1 2 | | TYK11 2 3 5 | | Protein Tyrosine Kinase 12 3 | | EC 2.7.10.13 8 | | Leukocyte Tyrosine Kinase1 | | Leukocyte Tyrosine Kinase Receptor2 |
Export aliases for LTK gene to outside databasesPrevious GC identifers: GC15M037163 GC15M034691 GC15M039374 GC15M039511 GC15M039583 GC15M018644 |
Summaries
for LTK gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for LTK:
The protein encoded by this gene is a member of the ros/insulin receptor family of tyrosine kinases. Tyrosine-specificphosphorylation of proteins is a key to the control of diverse pathways leading to cell growth and differentiation.Multiple transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq, Oct 2008)
UniProtKB/Swiss-Prot: LTK_HUMAN, P29376Function: Orphan receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known.Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors,such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cellsurvival. Signaling appears to involve the PI3 kinase pathway. Involved in regulation of the secretory pathwayinvolving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport
Gene Wiki entry for LTK (Leukocyte receptor tyrosine kinase)
|
Genomic Views
for LTK gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010194.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the LTK gene promoter:
E2F-4 E2F-3a NF-1 E2F-5 Pax-5 Brachyury E2F-2 Evi-1 E2F E2F-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for LTK
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LTK |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q15.1-q21.1 Ensembl cytogenetic band: 15q15.1 HGNC cytogenetic band: 15q15.1-q21.1LTK Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15M041795: view genomic region
(about GC identifiers)
Start:
|
41,795,836 bp from pter |
End:
|
41,806,085 bp from pter |
Size:
|
10,250 bases |
Orientation:
|
minus strand |
|
Proteins
for LTK gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: LTK_HUMAN, P29376 (See
protein sequence)Recommended Name: Leukocyte tyrosine kinase receptor precursor Size: 864 amino acids; 91681 Da
Subunit: Homodimer when bound to ligand (Probable). Part of a complex including LTK, TNK2 and GRB2, in which GRB2promotes LTK recruitment by TNK2
Subcellular location: Membrane; Single-pass type I membrane protein
Miscellaneous: Transgenic mice expressing human LTK show specific activation (tyrosine phosphorylation, kinaseactivity, membrane localization and homooligomerization) in heart combined with cardiac hypertrophy, cardiomyocytedegeneration
Secondary accessions: A6NNJ8 B4DL89 E9PFX4Alternative splicing: 5 isoforms: P29376-1 P29376-2 P29376-3 P29376-4 P29376-5 Explore the universe of human proteins at neXtProt for LTK: NX_P29376
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P29376
4/5 DME Specific Peptides for LTK (P29376) (see all 5)
LTK Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001129157.1 NP_002335.2 NP_996844.1
ENSEMBL proteins: ENSP00000347293 ENSP00000263800 ENSP00000458111 ENSP00000392196
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
LTK for ontologies About GeneDecksing
LTK Antibody Products:
Assay Products for LTK: |
Protein
Domains /
Families
for LTK gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
LTK for domains About GeneDecksing
5/8 InterPro domains/families (see all 8):Graphical View of Domain Structure for InterPro Entry P29376ProtoNet protein and cluster: P29376 2 Blocks protein families: IPB002011 Receptor tyrosine kinase IPB008266 Tyrosine protein kinase
UniProtKB/Swiss-Prot: LTK_HUMAN, P29376Similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. Insulin receptor subfamilySimilarity: Contains 1 protein kinase domain |
Function
for LTK gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: LTK_HUMAN, P29376Function: Orphan receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known.Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors,such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cellsurvival. Signaling appears to involve the PI3 kinase pathway. Involved in regulation of the secretory pathwayinvolving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transportCatalytic activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate Genatlas biochemistry entry for LTK:tyrosine kinase,receptor type,leukocyte
Enzyme Number (IUBMB): EC 2.7.10.11 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for LTK (see all 10)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for LTK (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): LTK (NM_001135685) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for LTK | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LTK |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LTK |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
LTK for ontologies About GeneDecksing
5 GenomeRNAi human phenotypes for LTK:
|
Pathways & Interactions
for LTK gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for LTK
STRING Interaction
Network Preview (showing 5 interactants - click image to see 10)
5/10 Interacting proteins for LTK (P293762, 3 ENSP000002638004) via UniProtKB, MINT, STRING, and/or I2D (see all 10)About this table
Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8): About this table
LTK for ontologies About GeneDecksing
|
Drugs & Compounds
for LTK gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
LTK for compounds About GeneDecksing
 Browse Tocris compounds for LTK
1 Novoseek chemical compound relationship for LTK gene About this table
Search CenterWatch for drugs/clinical trials and news about LTK
|
Transcripts
for LTK gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for LTK gene (3 alternative transcripts): NM_001135685.1 NM_002344.5 NM_206961.3 Unigene Cluster for LTK: Leukocyte receptor tyrosine kinase Hs.434481 [show with all ESTs]Unigene Representative Sequence: NM_0023446 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000355166(uc001zob.3 uc010ucx.1) ENST00000263800 ENST00000563518(uc001zoa.3 uc010bcg.2)
ENST00000561619 ENST00000453182 ENST00000569283
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for LTK (see all 10)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for LTK (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): LTK (NM_001135685) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for LTK | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LTK |
Additional cDNA sequence: AK296892.1 AK314006.1 BC143903.1 D16105.1 X52213.1 X60702.1 3 DOTS entries: DT.406078 DT.92417941 DT.100652500 24 AceView cDNA sequences: BX280153 BQ069815 D16105 NM_206961 BQ918753 CA394397 NM_002344 CR611113 BI462072 AL547896 BX353410 BC045607 BI765396 X52213 X60702 AW451303 BG024154 BX329448 BX389612 AI439603 BX344889 AL572671 BX344888 AI365420
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for LTK About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13a | · | 13b | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 |
|---|
|
| SP1: | | | | | | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | - | | - | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for LTK
|
Expression
for LTK gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| LTK expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GGGAGCACTG
About this image
See LTK Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for LTK
SOURCE GeneReport for Unigene cluster: Hs.434481
UniProtKB/Swiss-Prot: LTK_HUMAN, P29376Tissue specificity: Expressed in non-hematopoietic cell lines and T- and B-cell lines
SABiosciences Custom PCR Arrays for LTK
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for LTK
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat LTK | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LTK | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LTK | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LTK |
Orthologs
for LTK gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for LTK gene from 5/11 species (see all 11) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
LTK1 |
leukocyte receptor tyrosine kinase |
62.35(n)
63.59(a) |
|
423216 XM_421140.3 XP_421140.3 |
lizard
(Anolis carolinensis) |
Reptilia |
LTK6 |
-- |
40(a) |
1 ↔ 1 |
1(41513958-41585098) |
zebrafish
(Danio rerio) |
Actinopterygii |
ltk6 |
leukocyte tyrosine kinase |
31(a) |
1 ↔ 1 |
17(31459694-31542579) |
fruit fly
(Drosophila melanogaster) |
Insecta |
Alk6 |
Alk |
18(a) |
1 → many |
2R(12512798-12527516) |
worm
(Caenorhabditis elegans) |
Secernentea |
scd-23 |
protein kinase |
36(a) |
|
V(6635869-6642021) -- |
ENSEMBL Gene Tree for LTK (if available)
TreeFam Gene Tree for LTK (if available) |
Paralogs
for LTK gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for LTK gene
- INSR2 ROR12 ROS12 NTRK22 IGF1R2 DDR12 NTRK32 ROR22
- INSRR2 DDR22 MUSK2 ALK2 NTRK12
18/45 SIMAP similar genes for LTK using alignment to 3 protein entries: LTK_HUMAN (see all proteins)
(see all similar genes):EML4-ALK variant 7 KIF5B-ALK PPFIBP1-ALK SQSTM1-ALK EML4-ALK EML4-ALK variant 6
EML4/ALK fusion TFG/ALK fusion FLT1 FLT4 ALK MET
tec TXK DKFZp434L0319 PTK7 ABL1 BTK kinase deficient isoform 6
LTK for paralogs About GeneDecksing
|
Genomic Variants
for LTK gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for LTK (41795836 - 41806085 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for LTK
2 CNVs: 7060 29977
Human Gene Mutation Database (HGMD): LTK
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing LTK |
|
Disorders
/ Diseases
for LTK gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
LTK for disorders About GeneDecksing
OMIM gene information: 151520
OMIM disorders: --
UniProtKB/Swiss-Prot: LTK_HUMAN, P29376
Note=Genetic variations in LTK that cause up-regulation of the PI3K pathway may possibly contribute tosusceptibility to abnormal proliferation of self-reactive B-cells and, therefore, to systemic lupus erythematosus(SLE). SLE is a chronic, inflammatory and often febrile multisystemic disorder of connective tissue, thought torepresent a failure of the regulatory mechanisms of the autoimmune system
11  diseases for LTK: About MalaCardsnon-hodgkin lymphoma systemic lupus erythematosus reticulosarcoma lupus erythematosus
hodgkin's lymphoma breast carcinoma choroiditis gastric cancer
lung cancer carcinoma neuronitis
4 Novoseek disease relationships for LTK gene About this table
Human Genome Epidemiology (HuGE) Navigator: LTK (1 document)
Tumor Gene Database (TGDB): LTK
Export disorders for LTK gene to outside databases
|
Publications
for LTK gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for LTK gene, integrated from 9 sources (see all 40):
(articles sorted by number of sources associating them with LTK) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Human ltk: gene structure and preferential expression in human leukemic cells. (PubMed id 2320375)1, 2, 3 Maru Y.... Takaku F. (1990)
- Gain-of-function polymorphism in mouse and human Ltk: implications for the pathogenesis of systemic lupus erythematosus. (PubMed id 14695357)1, 2, 9 Li N....Hirose S. (2004)
- The phosphatidylinositol 3' kinase pathway is required for the survival signal of leukocyte tyrosine kinase. (PubMed id 9223670)1, 2, 9 Ueno H....Hirai H. (1997)
- Differently spliced cDNAs of human leukocyte tyrosine kinase receptor tyrosine kinase predict receptor proteins with and without a tyrosine kinase domain and a soluble receptor protein. (PubMed id 7685902)1, 2, 9 Toyoshima H.... Hirai H. (1993)
- Cytoplasmic ACK1 interaction with multiple receptor t yrosine kinases is mediated by Grb2: an analysis of ACK1 effects on Axl signali ng. (PubMed id 19815557)1, 2, 9 Pao-Chun L....Manser E. (2009)
- Human ltk receptor tyrosine kinase binds to PLC-gamma 1, PI3-K, GAP and Raf-1 in vivo. (PubMed id 8084603)1, 2, 9 Kozutsumi H....Hirai H. (1994)
- Identification and chromosomal mapping of new human tyrosine kinase genes. (PubMed id 2156206)1, 2, 9 Krolewski J.J.... Dalla-Favera R. (1990)
- Heart-specific activation of LTK results in cardiac h ypertrophy, cardiomyocyte degeneration and gene reprogramming in transgenic mic e. (PubMed id 10445845)1, 2 Honda H....Hirai H. (1999)
- The ltk gene encodes a novel receptor-type protein tyrosine kinase. (PubMed id 1655406)1, 2 Krolewski J.J. and Dalla-Favera R. (1991)
- Growth and survival signals transmitted via two distinct NPXY motifs within leukocyte tyrosine kinase, an insulin receptor-related tyrosine kinase. (PubMed id 8910363)1, 9 Ueno H....Hirai H. (1996)
|
External Searches for LTK gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing LTK gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing LTK gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing LTK gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
|
About This Section
| Patent Information for LTK gene:
Search GeneIP for patents involving LTK
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for LTK gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | OriGene Antibodies for LTK | | OriGene shRNA RFP for LTK | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for LTK | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for LTK | | | OriGene Protein Over-expression Lysate for LTK | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for LTK | | OriGene 3'-UTR Clone for LTK | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for LTK | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for LTK | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for LTK | | OriGene Custom Protein Services for LTK | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat LTK | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing LTK | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LTK | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LTK | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LTK | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LTK |
| |
 |  |  |  | |
| | | | Search Tocris compounds for LTK |
| |  |  |  |  | | | | |
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 | | | LTK Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LTK |
|  |  |  | | | | ThermoFisher Antibodies for LTK |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LTK |
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