Aliases for LST1 Gene
External Ids for LST1 Gene
Previous GeneCards Identifiers for LST1 Gene
The protein encoded by this gene is a membrane protein that can inhibit the proliferation of lymphocytes. Expression of this gene is enhanced by lipopolysaccharide, interferon-gamma, and bacteria. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
GeneCards Summary for LST1 Gene
LST1 (Leukocyte Specific Transcript 1) is a Protein Coding gene. Diseases associated with LST1 include hyperbilirubinemia, rotor type, digenic.
UniProtKB/Swiss-Prot for LST1 Gene
Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation.