Aliases for LSM2 Gene
External Ids for LSM2 Gene
Previous HGNC Symbols for LSM2 Gene
Previous GeneCards Identifiers for LSM2 Gene
This gene encodes a member of the LSm family of RNA-binding proteins. LSm proteins form stable heteromers that bind specifically to the 3'-terminal oligo(U) tract of U6 snRNA and may play a role in pre-mRNA splicing by mediating U4/U6 snRNP formation. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 19. [provided by RefSeq, Nov 2011]
GeneCards Summary for LSM2 Gene
LSM2 (LSM2 Homolog, U6 Small Nuclear RNA And MRNA Degradation Associated) is a Protein Coding gene. Diseases associated with LSM2 include Spinal Muscular Atrophy and Rheumatic Disease. Among its related pathways are mRNA Splicing - Major Pathway and Deadenylation-dependent mRNA decay. GO annotations related to this gene include poly(A) RNA binding and Ral GTPase binding.
UniProtKB/Swiss-Prot for LSM2 Gene
Binds specifically to the 3-terminal U-tract of U6 snRNA. May be involved in pre-mRNA splicing.