Aliases for LSM14A Gene
External Ids for LSM14A Gene
Previous HGNC Symbols for LSM14A Gene
Previous GeneCards Identifiers for LSM14A Gene
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family (see SNRPD2; 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.[supplied by OMIM, Mar 2008]
GeneCards Summary for LSM14A Gene
LSM14A (LSM14A, MRNA Processing Body Assembly Factor) is a Protein Coding gene. Diseases associated with LSM14A include Autoimmune Disease Of Urogenital Tract. GO annotations related to this gene include poly(A) RNA binding and double-stranded RNA binding. An important paralog of this gene is LSM14B.
UniProtKB/Swiss-Prot for LSM14A Gene
Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for non-translating mRNAs.