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LSM14A Gene

protein-coding   GIFtS: 46
GCID: GC19P034663

LSM14A, SCD6 Homolog A (S. Cerevisiae)

(Previous names: chromosome 19 open reading frame 13, family with sequence...)
(Previous symbols: C19orf13, FAM61A)
  Search for LSM14A
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
LSM14A, SCD6 Homolog A (S. Cerevisiae)1 2     RNA-Associated Protein 55A2 3
C19orf131 2 3     Chromosome 19 Open Reading Frame 131
FAM61A1 2 3     LSM14 Homolog A (SCD6, S. Cerevisiae)1
Family With Sequence Similarity 61, Member A1 2     alphaSNBP2
Protein SCD6 Homolog2 3     LSM14 Homolog A2
Putative Alpha-Synuclein-Binding Protein2 3     Protein LSM14 Homolog A2
RAP552 3     RNA-Associated Protein 552
RAP55A2 3     AlphaSNBP3
hRAP552 3     Protein FAM61A3
hRAP55A2 3     

External Ids:    HGNC: 244891   Entrez Gene: 260652   Ensembl: ENSG000002571037   OMIM: 6106775   UniProtKB: Q8ND563   

Export aliases for LSM14A gene to outside databases

Previous GC identifers: GC19P039359 GC19P031161


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for LSM14A Gene:
Sm-like proteins were identified in a variety of organisms based on sequence homology with the Sm protein family
(see SNRPD2; 601061). Sm-like proteins contain the Sm sequence motif, which consists of 2 regions separated by a
linker of variable length that folds as a loop. The Sm-like proteins are thought to form a stable heteromer
present in tri-snRNP particles, which are important for pre-mRNA splicing.(supplied by OMIM, Mar 2008)

GeneCards Summary for LSM14A Gene:
LSM14A (LSM14A, SCD6 homolog A (S. cerevisiae)) is a protein-coding gene. GO annotations related to this gene include double-stranded DNA binding and single-stranded RNA binding. An important paralog of this gene is LSM14B.

UniProtKB/Swiss-Prot: LS14A_HUMAN, Q8ND56
Function: Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for
non-translating mRNAs




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the LSM14A gene promoter:
         AML1a   NRSF form 1   HSF1 (long)   NRSF form 2   YY1   N-Myc   POU2F1   POU2F1a   FOXJ2 (long isoform)   HSF1short   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidLSM14A promoter sequence
   Search Chromatin IP Primers for LSM14A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat LSM14A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.11   Ensembl cytogenetic band:  19q13.11   HGNC cytogenetic band: 19q13.12

LSM14A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
LSM14A gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P034663:  view genomic region     (about GC identifiers)

Start:
34,663,352 bp from pter      End:
34,720,420 bp from pter
Size:
57,069 bases      Orientation:
plus strand

1 alternative location:
Chr19+,NW_003315963 20,188-77,263     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: LS14A_HUMAN, Q8ND56 (See protein sequence)
Recommended Name: Protein LSM14 homolog A  
Size: 463 amino acids; 50530 Da
Subunit: Component of a ribonucleoprotein (RNP) complex (By similarity)
Sequence caution: Sequence=BAB55066.1; Type=Erroneous initiation;
Secondary accessions: Q76LX7 Q96AR3 Q96K73 Q96SN5 Q9UFR3
Alternative splicing: 2 isoforms:  Q8ND56-1   Q8ND56-2   

Explore the universe of human proteins at neXtProt for LSM14A: NX_Q8ND56

Explore proteomics data for LSM14A at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See LSM14A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001107565.1  NP_056393.2  

    ENSEMBL proteins: 
     ENSP00000468130   ENSP00000446451   ENSP00000446271   ENSP00000413964   ENSP00000466725  

    LSM14A Human Recombinant Protein Products:

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    Novus Biologicals LSM14A Protein
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for LSM14A 

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    Search eBioscience for ELISAs for LSM14A 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    Selected InterPro protein domains (see all 6):
     IPR025609 Lsm14_N
     IPR025761 FFD_box
     IPR025768 TFG_box
     IPR010920 LSM_dom
     IPR019050 FDF_dom

    Graphical View of Domain Structure for InterPro Entry Q8ND56

    ProtoNet protein and cluster: Q8ND56

    UniProtKB/Swiss-Prot: LS14A_HUMAN, Q8ND56
    Domain: The LSM14 domain and the RGG repeats are required for accumulation in P-bodies, and the region containing
    the FDF motif is responsible for cytoplasmic retention
    Similarity: Belongs to the LSM14 family
    Similarity: Contains 1 DFDF domain


    Find genes that share domains with LSM14A           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: LS14A_HUMAN, Q8ND56
    Function: Essential for formation of P-bodies, cytoplasmic structures that provide storage sites for
    non-translating mRNAs

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003690double-stranded DNA binding IEA--
    GO:0003725double-stranded RNA binding IEA--
    GO:0003727single-stranded RNA binding IEA--
    GO:0044822poly(A) RNA binding IDA--
         
    Find genes that share ontologies with LSM14A           About GenesLikeMe


    Phenotypes:
         1 MGI phenotypic allele for Lsm14a (no phenotypes)

    Find genes that share phenotypes with LSM14A           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for LSM14A
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    miRNA
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    miRTarBase miRNAs that target LSM14A:
    hsa-mir-320c (MIRT036176), hsa-mir-615-3p (MIRT039909), hsa-mir-26a-5p (MIRT050086), hsa-mir-196a-5p (MIRT048221), hsa-mir-15b-5p (MIRT046444), hsa-mir-17-5p (MIRT050982), hsa-mir-182-5p (MIRT047190)

    Block miRNA regulation of human, mouse, rat LSM14A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate LSM14A (see all 33):
    hsa-miR-300 hsa-miR-16-1* hsa-miR-9 hsa-miR-155 hsa-miR-433 hsa-miR-3163 hsa-miR-1298 hsa-miR-3136-5p
    SwitchGear 3'UTR luciferase reporter plasmidLSM14A 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for LSM14A
    Predesigned siRNA for gene silencing in human, mouse, rat LSM14A

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 2): LSM14A (NM_015578)
    Sino Biological Human cDNA Clone for LSM14A
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LSM14A

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LSM14A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    LS14A_HUMAN, Q8ND56: Cytoplasm. Cytoplasm, P-body. Note=Targeted to stress granules (SGs) in response to cellular
    stress
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    Gene Ontology (GO): 4 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000932cytoplasmic mRNA processing body IDA16484376
    GO:0005737cytoplasm IDA--
    GO:0010494cytoplasmic stress granule IDA16484376
    GO:0043231intracellular membrane-bounded organelle IDA--

    Find genes that share ontologies with LSM14A           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for LSM14A
    Interactions:

        Search GeneGlobe Interaction Network for LSM14A

    Selected Interacting proteins for LSM14A (Q8ND563) via UniProtKB, MINT, STRING, and/or I2D (see all 31)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ENSG00000172850Q9Y3333I2D: score=1 
    ENSG00000224979Q9Y3333I2D: score=1 
    ENSG00000225998Q9Y3333I2D: score=1 
    ENSG00000231502Q9Y3333I2D: score=1 
    ENSG00000236826Q9Y3333I2D: score=1 
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    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006417regulation of translation IEA--
    GO:0007275multicellular organismal development IEA--
    GO:0033962cytoplasmic mRNA processing body assembly IMP17074753
    GO:0039529RIG-I signaling pathway IEA--
    GO:0051607defense response to virus ----

    Find genes that share ontologies with LSM14A           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for LSM14A (LS14A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for LSM14A gene (2 alternative transcripts): 
    NM_001114093.1  NM_015578.2  

    8 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000589878 ENST00000540746 ENST00000544216(uc002nva.4 uc002nvc.4)
    ENST00000433627(uc002nvb.4 uc010xru.2) ENST00000586157 ENST00000588582
    ENST00000585887 ENST00000590416
    miRNA
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    Block miRNA regulation of human, mouse, rat LSM14A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate LSM14A (see all 33):
    hsa-miR-300 hsa-miR-16-1* hsa-miR-9 hsa-miR-155 hsa-miR-433 hsa-miR-3163 hsa-miR-1298 hsa-miR-3136-5p
    SwitchGear 3'UTR luciferase reporter plasmidLSM14A 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat LSM14A
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    GenScript: all cDNA clones in your preferred vector (see all 2): LSM14A (NM_015578)
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    Primer
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat LSM14A
      QuantiTect SYBR Green Assays in human, mouse, rat LSM14A
      QuantiFast Probe-based Assays in human, mouse, rat LSM14A

    Selected AceView cDNA sequences (see all 320):

    AW150395 BM834805 AA770570 AB069975 CA419532 AA744743 BG054966 AI654540 
    AA745865 BE907270 CD515912 AA382815 AA327383 N72416 AA636001 AI581633 
    AI745698 AA446971 BU679586 BQ023329 BI493124 AA337392 AI619616 AI686027 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    LSM14A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCATACCTGC
    LSM14A Expression
    About this image

    LSM14A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    LSM14A Protein Expression
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LSM14A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of eukaryotes.

    Orthologs for LSM14A gene from Selected species (see all 19)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Lsm14a1 , 5 LSM14 homolog A (SCD6, S. cerevisiae)1, 5 90.5(n)1
    94.74(a)1
      7 (19.56 cM)5
    670701  NM_025948.21  NP_080224.11 
     343446465 
    chicken
    (Gallus gallus)
    Aves LSM14A1 LSM14A, SCD6 homolog A (S. cerevisiae) 84.13(n)
    91.3(a)
      415781  NM_001012778.1  NP_001012796.1 
    lizard
    (Anolis carolinensis)
    Reptilia LSM14A6
    LSM14A, SCD6 homolog A (S. cerevisiae)
    85(a)
    1 ↔ 1
    GL344074.1(33545-48268)
    African clawed frog
    (Xenopus laevis)
    Amphibia MGC533502 hypothetical protein MGC53350 79.7(n)    BC042251.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufa10g112 Danio rerio mRNA similar to DKFZP434D1335 protein (cDNA more 77.24(n)    BC047185.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta tral6
    trailer hitch
    22(a)
    1 → many
    3L(12508159-12514054)
    worm
    (Caenorhabditis elegans)
    Secernentea car-16
    Protein CAR-1 (car-1) mRNA, complete cds
    44(a)
    1 → many
    I(12904470-12906358) WBGene00012484
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes SCD66
    Protein containing an Lsm domain; negatively regul...
    30(a)
    1 → many
    XVI(792687-793736) YPR129W
    rice
    (Oryza sativa)
    Liliopsida AK102802.12   -- 77.02(n)    AK102802.1 


    ENSEMBL Gene Tree for LSM14A (if available)
    TreeFam Gene Tree for LSM14A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for LSM14A gene
    LSM14B2  
    1 SIMAP similar gene for LSM14A using alignment to 4 protein entries:     LS14A_HUMAN (see all proteins):
    LSM14B

    Find genes that share paralogs with LSM14A           About GenesLikeMe


    2 Pseudogenes.org Pseudogenes for LSM14A
    PGOHUM00000261888 PGOHUM00000243764


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for LSM14A (see all 1164)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1839183451,2
    C--34661457(+) GTGAGA/GCTGTC 2 -- us2k10--------
    rs1145064591,2
    F--34661488(+) AATTCA/GACTTC 2 -- us2k11Minor allele frequency- G:0.04WA 118
    rs1852096491,2
    --34661517(+) TGAAAC/TAGGGA 2 -- us2k10--------
    rs1149830091,2
    F--34661536(+) CCTTTC/TTTTGT 2 -- us2k11Minor allele frequency- T:0.04WA 118
    rs1432749601,2
    C--34661871(+) TTAAGG/TAGATG 2 -- us2k10--------
    rs711656301,2
    C--34662097(+) TTTTTT/-GAGAC 2 -- us2k11Minor allele frequency- -:0.00NA 2
    rs1899189481,2
    C--34662288(+) AGACGA/GGGTTT 2 -- us2k10--------
    rs1507349421,2
    --34662361(+) AAGTAC/GTGGGA 2 -- us2k10--------
    rs1159708711,2
    F--34662405(+) TTAGAT/CTTTAA 2 -- us2k11Minor allele frequency- C:0.06WA 118
    rs356903591,2
    C,F,H--34662450(+) TACTGG/TGGGCA 2 -- us2k114Minor allele frequency- T:0.13NS EA NA 1696

    HapMap Linkage Disequilibrium report for LSM14A (34663352 - 34720420 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for LSM14A:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv509737CNV Insertion20534489
    nsv2467CNV Insertion18451855

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing LSM14A
    DNA2.0 Custom Variant and Variant Library Synthesis for LSM14A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610677    OMIM disorders: --

    1 disease from the University of Copenhagen DISEASES database for LSM14A:
    Primary biliary cirrhosis

    Find genes that share disorders with LSM14A           About GenesLikeMe


    Export disorders for LSM14A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for LSM14A gene, integrated from 10 sources (see all 37):
    (articles sorted by number of sources associating them with LSM14A)
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    1. RAP55: insights into an evolutionarily conserved protein family. (PubMed id 18723115)1, 2 Marnef A.... Ladomery M.R. (Int. J. Biochem. Cell Biol. 2009)
    2. RAP55, a cytoplasmic mRNP component, represses translation in Xenopus oocytes. (PubMed id 17074753)1, 2 Tanaka K.J....Tsujimoto M. (J. Biol. Chem. 2006)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    4. RNA-associated protein 55 (RAP55) localizes to mRNA processing bodies and stress granules. (PubMed id 16484376)1, 2 Yang W.H.... Bloch D.B. (RNA 2006)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    8. The HECT type ubiquitin ligase NEDL2 is degraded by anaphase-promoting complex/cyclosome (APC/C)-Cdh1, and its tight regulation maintains the metaphase to anaphase transition. (PubMed id 24163370)1 Lu L....Zhang L. (J. Biol. Chem. 2013)
    9. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (Cell 2012)
    10. Comparative large scale characterization of plant versus mammal proteins reveals similar and idiosyncratic N-I+-acetylation features. (PubMed id 22223895)2 Bienvenut W.V....Giglione C. (amp 2012)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 26065 HGNC: 24489 AceView: C19orf13 Ensembl:ENSG00000257103 euGenes: HUgn26065
    ECgene: LSM14A H-InvDB: LSM14A

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for LSM14A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for LSM14A gene:
    Search GeneIP for patents involving LSM14A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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