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Aliases for LSM12 Gene

Aliases for LSM12 Gene

  • LSM12 Homolog (S. Cerevisiae) 2 3
  • Protein LSM12 Homolog 3
  • PNAS-135 3

External Ids for LSM12 Gene

Previous GeneCards Identifiers for LSM12 Gene

  • GC17M039468
  • GC17M042112
  • GC17M037876

Summaries for LSM12 Gene

GeneCards Summary for LSM12 Gene

LSM12 (LSM12 Homolog (S. Cerevisiae)) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LSM12 Gene

Genomics for LSM12 Gene

Regulatory Elements for LSM12 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for LSM12 Gene

Start:
44,034,635 bp from pter
End:
44,067,619 bp from pter
Size:
32,985 bases
Orientation:
Minus strand

Genomic View for LSM12 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for LSM12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LSM12 Gene

Proteins for LSM12 Gene

  • Protein details for LSM12 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q3MHD2-LSM12_HUMAN
    Recommended name:
    Protein LSM12 homolog
    Protein Accession:
    Q3MHD2
    Secondary Accessions:
    • Q86YB1
    • Q96NL5

    Protein attributes for LSM12 Gene

    Size:
    195 amino acids
    Molecular mass:
    21701 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for LSM12 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for LSM12 Gene

Proteomics data for LSM12 Gene at MOPED

Post-translational modifications for LSM12 Gene

  • Ubiquitination at Lys86
  • Modification sites at PhosphoSitePlus

Other Protein References for LSM12 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for LSM12 Gene

Domains for LSM12 Gene

Protein Domains for LSM12 Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for LSM12 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q3MHD2

UniProtKB/Swiss-Prot:

LSM12_HUMAN :
  • Q3MHD2
Family:
  • Belongs to the LSM12 family.
genes like me logo Genes that share domains with LSM12: view

No data available for Gene Families for LSM12 Gene

Function for LSM12 Gene

Phenotypes for LSM12 Gene

GenomeRNAi human phenotypes for LSM12:
genes like me logo Genes that share phenotypes with LSM12: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for LSM12

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Animal Models , Transcription Factor Targeting and HOMER Transcription for LSM12 Gene

Localization for LSM12 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for LSM12 Gene COMPARTMENTS Subcellular localization image for LSM12 gene
Compartment Confidence
cytosol 2
nucleus 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for LSM12 Gene

Pathways for LSM12 Gene

SuperPathways for LSM12 Gene

No Data Available

Gene Ontology (GO) - Biological Process for LSM12 Gene

None

No data available for Pathways by source for LSM12 Gene

Transcripts for LSM12 Gene

Unigene Clusters for LSM12 Gene

LSM12 homolog (S. cerevisiae):
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for LSM12

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for LSM12 Gene

No ASD Table

Relevant External Links for LSM12 Gene

GeneLoc Exon Structure for
LSM12
ECgene alternative splicing isoforms for
LSM12

Expression for LSM12 Gene

mRNA expression in normal human tissues for LSM12 Gene

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for LSM12 Gene

SOURCE GeneReport for Unigene cluster for LSM12 Gene Hs.355570

genes like me logo Genes that share expressions with LSM12: view

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for LSM12 Gene

Orthologs for LSM12 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for LSM12 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LSM12 35
  • 99.83 (n)
  • 100 (a)
LSM12 36
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LSM12 35
  • 98.29 (n)
  • 100 (a)
LSM12 36
  • 100 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LSM12 35
  • 98.63 (n)
  • 100 (a)
LSM12 36
  • 92 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Lsm12 35
  • 97.09 (n)
  • 100 (a)
Lsm12 16
Lsm12 36
  • 100 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia LSM12 36
  • 91 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Lsm12 35
  • 97.09 (n)
  • 100 (a)
chicken
(Gallus gallus)
Aves LSM12 36
  • 94 (a)
OneToOne
TMEM101 35
  • 85.84 (n)
  • 93.78 (a)
lizard
(Anolis carolinensis)
Reptilia LSM12 36
  • 94 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.25564 35
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC394627 35
rainbow trout
(Oncorhynchus mykiss)
Actinopterygii Omy.10493 35
zebrafish
(Danio rerio)
Actinopterygii lsm12a 36
  • 77 (a)
OneToMany
lsm12b 35
  • 78.8 (n)
  • 85.64 (a)
lsm12b 36
  • 85 (a)
OneToMany
wufe01f11 35
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP002167 35
  • 51.55 (n)
  • 45.35 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG14164 36
  • 30 (a)
OneToMany
CG15735 35
  • 46.09 (n)
  • 33.95 (a)
CG15735 36
  • 28 (a)
OneToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes LSM12 36
  • 24 (a)
OneToOne
LSM12 38
Species with no ortholog for LSM12:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for LSM12 Gene

ENSEMBL:
Gene Tree for LSM12 (if available)
TreeFam:
Gene Tree for LSM12 (if available)

Paralogs for LSM12 Gene

genes like me logo Genes that share paralogs with LSM12: view

No data available for Paralogs for LSM12 Gene

Variants for LSM12 Gene

Sequence variations from dbSNP and Humsavar for LSM12 Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs170635 -- 44,038,953(-) CTGCC(A/G)TCTGT intron-variant
rs179267 -- 44,064,006(-) GTTTT(A/C)TATGC intron-variant
rs189051 -- 44,061,070(-) AAAGT(C/G)CTGGA intron-variant
rs228751 -- 44,042,710(-) gcagg(C/T)gcctg intron-variant
rs228752 -- 44,044,712(-) TTTGA(A/G)AAAAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for LSM12 Gene

Variant ID Type Subtype PubMed ID
nsv833454 CNV Loss 17160897
esv2662976 CNV Deletion 23128226

Relevant External Links for LSM12 Gene

HapMap Linkage Disequilibrium report
LSM12

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LSM12 Gene

Disorders for LSM12 Gene

(1) University of Copenhagen DISEASES for LSM12 Gene

genes like me logo Genes that share disorders with LSM12: view

No data available for UniProtKB/Swiss-Prot for LSM12 Gene

Publications for LSM12 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. Novel Sm-like proteins with long C-terminal tails and associated methyltransferases. (PMID: 15225602) Albrecht M. … Lengauer T. (FEBS Lett. 2004) 2 3
  3. A human protein-protein interaction network: a resource for annotating the proteome. (PMID: 16169070) Stelzl U. … Wanker E.E. (Cell 2005) 3
  4. Large-scale analysis of the human ubiquitin-related proteome. (PMID: 16196087) Matsumoto M. … Nakayama K.I. (Proteomics 2005) 3
  5. Large-scale mapping of human protein-protein interactions by mass spectrometry. (PMID: 17353931) Ewing R.M. … Figeys D. (Mol. Syst. Biol. 2007) 3

Products for LSM12 Gene

Sources for LSM12 Gene

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