LRWD1 Gene
protein-coding GIFtS: 44
GCID: GC07P102105
|
|
leucine-rich repeats and WD repeat domain containing 1
| |
Aliases
for LRWD1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Leucine-Rich Repeats And WD Repeat Domain Containing 11 2 | | DKFZp434K18151 | | ORCA1 2 3 | | Centromere Protein 332 | | CENP-331 2 | | Leucine-Rich Repeat And WD Repeat-Containing Protein 12 | | Origin Recognition Complex-Associated Protein2 3 | | Origin Recognition Complex Associated2 | | ORC-Associated Protein2 3 | | |
Export aliases for LRWD1 gene to outside databasesPrevious GC identifers: GC07P101893 GC07P096695 |
Summaries
for LRWD1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: LRWD1_HUMAN, Q9UFC0Function: Associated component of the origin recognition complex (ORC) required to recruit and stabilize the ORCcomplex to chromatin. Probably required for the association of ORC on chromatin during G1 to establish pre-replicationcomplex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histonemethylation repressive marks on heterochromatin: binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 andH4K20me3 in a cooperative manner with DNA methylation. It is unclear whether it recognizes and binds these repressivemarks by itself or needs additional factors
|
Genomic Views
for LRWD1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007933.15 NT_079596.2
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the LRWD1 gene promoter:
p53 SRF (504 AA) GCNF Lmo2 GATA-2 HEN1 FAC1 GCNF-1 GCNF-2
Other transcription factors
Search SABiosciences Chromatin IP Primers for LRWD1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LRWD1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q22.1 Ensembl cytogenetic band: 7q22.1 HGNC cytogenetic band: 7q22.1LRWD1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P102105: view genomic region
(about GC identifiers)
Start:
|
102,105,376 bp from pter |
End:
|
102,113,615 bp from pter |
Size:
|
8,240 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 101,465,691-101,473,913 |
|
Proteins
for LRWD1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: LRWD1_HUMAN, Q9UFC0 (See
protein sequence)Recommended Name: Leucine-rich repeat and WD repeat-containing protein 1 Size: 647 amino acids; 70861 Da
Subunit: Component of the ORC complex
Subcellular location: Nucleus. Chromosome, centromere. Chromosome, telomere. Note=Localizes to heterochromatin duringG1 phase. Restricted to centromeres or telomeres as cells progress though S phase. When cells enter mitosis,relocalizes to centromeres
Secondary accessions: A8K4K2 B2R9G2 Q8N0T9 Q8WV43 Q96GJ2Explore the universe of human proteins at neXtProt for LRWD1: NX_Q9UFC0
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9UFC0
LRWD1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_690852.1
ENSEMBL proteins: ENSP00000292616 ENSP00000420650 ENSP00000418204 ENSP00000417913 ENSP00000420729 ENSP00000420544 ENSP00000420373
Human Recombinant Protein Products:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IDA | -- | | GO:0005664 | nuclear origin of replication recognition complex |
IDA | -- | | GO:0005721 | centromeric heterochromatin |
IDA | -- | | GO:0031933 | telomeric heterochromatin |
IDA | -- |
LRWD1 for ontologies About GeneDecksing
LRWD1 Antibody Products:
Assay Products for LRWD1: |
Protein
Domains /
Families
for LRWD1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
LRWD1 for domains About GeneDecksing
5/6 InterPro domains/families (see all 6):Graphical View of Domain Structure for InterPro Entry Q9UFC0ProtoNet protein and cluster: Q9UFC0 UniProtKB/Swiss-Prot: LRWD1_HUMAN, Q9UFC0Domain: The WD repeats are required for the interaction with ORC componentsSimilarity: Belongs to the LRWD1 familySimilarity: Contains 4 LRR (leucine-rich) repeatsSimilarity: Contains 5 WD repeats |
Function
for LRWD1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: LRWD1_HUMAN, Q9UFC0Function: Associated component of the origin recognition complex (ORC) required to recruit and stabilize the ORCcomplex to chromatin. Probably required for the association of ORC on chromatin during G1 to establish pre-replicationcomplex (preRC) and to heterochromatic sites in post-replicated cells. Binds a combination of DNA and histonemethylation repressive marks on heterochromatin: binds histone H3 and H4 trimethylation marks H3K9me3, H3K27me3 andH4K20me3 in a cooperative manner with DNA methylation. It is unclear whether it recognizes and binds these repressivemarks by itself or needs additional factors
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for LRWD1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for LRWD1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: LRWD1 (NM_152892) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for LRWD1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LRWD1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LRWD1 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
LRWD1 for ontologies About GeneDecksing
|
Pathways & Interactions
for LRWD1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for LRWD1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 15)
5/748 Interacting proteins for LRWD1 (Q9UFC02 ENSP000002926164) via UniProtKB, MINT, STRING, and/or I2D (see all 748)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000080 | G1 phase of mitotic cell cycle |
IMP | -- | | GO:0006270 | DNA replication initiation |
TAS | -- | | GO:0006325 | chromatin organization |
IMP | -- | | GO:0016568 | chromatin modification |
IEA | -- | | GO:0071169 | establishment of protein localization to chromatin |
IDA | -- |
LRWD1 for ontologies About GeneDecksing
|
Drugs & Compounds
for LRWD1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for LRWD1
Search CenterWatch for drugs/clinical trials and news about LRWD1
|
Transcripts
for LRWD1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for LRWD1 gene: NM_152892.1 Unigene Cluster for LRWD1: Leucine-rich repeats and WD repeat domain containing 1 Hs.274135 [show with all ESTs]Unigene Representative Sequence: AB2093799 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000292616(uc003uzn.3) ENST00000463739 ENST00000464107 ENST00000473880
ENST00000476270 ENST00000485808 ENST00000485417 ENST00000488689 ENST00000468175
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for LRWD1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for LRWD1
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: LRWD1 (NM_152892) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for LRWD1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LRWD1 |
Additional cDNA sequence: AB209379.1 AK290967.1 AK313771.1 AL133057.1 BC009436.1 BC018769.1 BC030547.1 18 DOTS entries: DT.100824847 DT.100884207 DT.102840197 DT.111585 DT.91842362 DT.92055183 DT.100824851 DT.100884206 DT.92330191 DT.97864593 DT.100824852 DT.100833157 DT.95358806 DT.100824831 DT.100039328 DT.100824832 DT.100824842 DT.91954606 24/243 AceView cDNA sequences (see all 243): CR620752 AL528301 BM764234 BM912168 BE855868 AI693780 BM845853 BQ940501 CD244224 BQ219016 AL133057 BM845875 BI827109 BI831009 BG900470 BQ083203 AL539519 BG331815 BM848360 BM835310 BM547405 BM848366 BM926877 AL554650
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for LRWD1 (see all 8) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11a | · | 11b | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16a | · | 16b | · | 16c |
|---|
|
| SP1: | | | | | | | | | - | | - | | | | | | | | | | - | | | | | | | | - | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP2: | | | | | | | | | | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for LRWD1
|
Expression
for LRWD1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| LRWD1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GTGAACACAG
About this image
See LRWD1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for LRWD1
SOURCE GeneReport for Unigene cluster: Hs.274135
SABiosciences Custom PCR Arrays for LRWD1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for LRWD1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat LRWD1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LRWD1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LRWD1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LRWD1 |
Orthologs
for LRWD1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for LRWD1 gene from 4/12 species (see all 12) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Lrwd11 , 5 |
leucine-rich repeats and WD repeat domain containing more1, 5 |
80.59(n)1
78.42(a)1 |
|
5 (75.80 cM)5
717351 NM_027891.41 NP_082167.21
1361227725 |
chicken
(Gallus gallus) |
Aves |
LRWD11 |
leucine-rich repeats and WD repeat domain containing more |
54.78(n)
48.91(a) |
|
417511 XM_415759.3 XP_415759.2 |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.319912 |
Xenopus laevis transcribed sequence with weak similarity more |
73.34(n) |
|
BJ611774.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
lrwd11 |
leucine-rich repeats and WD repeat domain containing more |
49.56(n)
38.41(a) |
|
327124 XM_678221.5 XP_683313.4 |
ENSEMBL Gene Tree for LRWD1 (if available)
TreeFam Gene Tree for LRWD1 (if available) |
Paralogs
for LRWD1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for LRWD1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 7 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for LRWD1 (102105376 - 102113615 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 4 variations for LRWD1
4 CNVs: 36585 4553 31385 70020 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing LRWD1 |
|
Disorders
/ Diseases
for LRWD1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
LRWD1 for disorders About GeneDecksing
5  diseases for LRWD1: About MalaCardstooth erosion dental caries nocardiosis gastroenteritis
rosacea
1 disease from the University of Copenhagen DISEASES database for LRWD1:Sertoli cell-only syndrome Export disorders for LRWD1 gene to outside databases
|
Publications
for LRWD1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for LRWD1 gene, integrated from 9 sources (see all 23):
(articles sorted by number of sources associating them with LRWD1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Quantitative interaction proteomics and genome-wide p rofiling of epigenetic histone marks and their readers. (PubMed id 20850016)1, 2, 3 Vermeulen M....Mann M. (2010)
- A WD-repeat protein stabilizes ORC binding to chromat in. (PubMed id 20932478)1, 2, 3 Shen Z....Prasanth S.G. (2010)
- Expression of lrwd1 in mouse testis and its centrosom al localization. (PubMed id 20180869)1, 3 Teng Y.N....Kuo T.Y. (2010)
- Leucine-rich repeat and WD repeat-containing protein 1 is recruited to pericentric heterochromatin by trimethylated lysine 9 of histon e H3 and maintains heterochromatin silencing. (PubMed id 22427655)1 Chan K.M. and Zhang Z. (2012)
- A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
- Dynamic association of ORCA with prereplicative comple x components regulates DNA replication initiation. (PubMed id 22645314)1 Shen Z....Prasanth S.G. (2012)
- Orc2 protects ORCA from ubiquitin-mediated degradation . (PubMed id 22935713)1 Shen Z. and Prasanth S.G. (2012)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (2010)
|
External Searches for LRWD1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing LRWD1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing LRWD1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing LRWD1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for LRWD1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for LRWD1 gene:
Search GeneIP for patents involving LRWD1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for LRWD1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for LRWD1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for LRWD1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for LRWD1 | | | OriGene Protein Over-expression Lysate for LRWD1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for LRWD1 | | OriGene 3'-UTR Clone for LRWD1 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for LRWD1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for LRWD1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for LRWD1 | | OriGene Custom Protein Services for LRWD1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat LRWD1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing LRWD1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat LRWD1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat LRWD1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat LRWD1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat LRWD1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for LRWD1 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | LRWD1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for LRWD1 |
|  |  |  | | | | Search ThermoFisher Antibodies for LRWD1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat LRWD1 |
|
|
|
|
